The Semi-Synthetic Peptide Lin-SB056-1 in Combination with EDTA Exerts Strong Antimicrobial and Antibiofilm Activity against Pseudomonas aeruginosa in Conditions Mimicking Cystic Fibrosis Sputum

Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens

(2017) Joanna E. Payne et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Clinical implications of Pseudomonas aeruginosa location in the lungs of patients with cystic fibrosis

(2017) J. E. Moore et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Increasing Incidence of Multidrug Resistance Among Cystic Fibrosis Respiratory Bacterial Isolates

(2017) W. Cliff Rutter et al.   Microbial Drug Resistance

Analogs of the Frog-skin Antimicrobial Peptide Temporin 1Tb Exhibit a Wider Spectrum of Activity and a Stronger Antibiofilm Potential as Compared to the Parental Peptide

(2017) Lucia Grassi et al.   Frontiers in Chemistry

Esculentin-1a-derived peptides promote clearance ofP. aeruginosainternalized in cystic fibrosis bronchial cells as well as lung cells migration: Biochemical properties and a plausible mode of action

(2016) Floriana Cappiello et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria

(2016) Giovanna Batoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Anti-biofilm properties of the antimicrobial peptide temporin 1Tb and its ability, in combination with EDTA, to eradicateStaphylococcus epidermidisbiofilms on silicone catheters

(2016) Giuseppantonio Maisetta et al.   BIOFOULING

Anti-biofilm peptides as a new weapon in antimicrobial warfare

(2016) Daniel Pletzer et al.   CURRENT OPINION IN MICROBIOLOGY

Membrane-active Antimicrobial Peptides as Template Structures for Novel Antibiotic Agents

(2016) Karl Lohner   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antimicrobial Peptides Under Clinical Trials

(2016) Katarzyna E. Greber et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

In vitro and in vivo activity of EDTA and antibacterial agents against the biofilm of mucoid Pseudomonas aeruginosa

(2016) Zhenqiu Liu et al.   INFECTION

The singular behavior of a β-type semi-synthetic two branched polypeptide: three-dimensional structure and mode of action

(2016) Giorgia Manzo et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Role of Multicellular Aggregates in Biofilm Formation

(2016) Kasper N. Kragh et al.   mBio

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

(2016) Anjali Y. Bhagirath et al.   BMC Pulmonary Medicine

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

(2015) Oana Ciofu et al.   ADVANCED DRUG DELIVERY REVIEWS

Rational modification of a dendrimeric peptide with antimicrobial activity: consequences on membrane-binding and biological properties

(2015) Giovanna Batoni et al.   AMINO ACIDS

d-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

(2015) Antonio Di Grazia et al.   AMINO ACIDS

BaAMPs: the database of biofilm-active antimicrobial peptides

(2015) Mariagrazia Di Luca et al.   BIOFOULING

Managing Pseudomonas aeruginosa respiratory infections in cystic fibrosis

(2015) Katherine M. Langan et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Aspects of pulmonary drug delivery strategies for infections in cystic fibrosis – where do we stand?

(2015) Mareike Klinger-Strobel et al.   Expert Opinion on Drug Delivery

In vitro activity of gentamicin, vancomycin or amikacin combined with EDTA or L-arginine as lock therapy against a wide spectrum of biofilm-forming clinical strains isolated from catheter-related infections

(2015) D. Lebeaux et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cystic fibrosis microbiology: Advances in antimicrobial therapy

(2015) Valerie Waters et al.   Journal of Cystic Fibrosis

The effects of d-Tyrosine combined with amikacin on the biofilms of Pseudomonas aeruginosa

(2015) Pengfei She et al.   MICROBIAL PATHOGENESIS

Enhanced Amphiphilic Profile of a Short β-Stranded Peptide Improves Its Antimicrobial Activity

(2015) Giorgia Manzo et al.   PLoS One

EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care

(2015) Simon Finnegan et al.   Advances in Wound Care

Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume

(2015) Tsiry Rasamiravaka et al.   PLoS One

Novel approaches to combat bacterial biofilms

(2014) Christophe Beloin et al.   CURRENT OPINION IN PHARMACOLOGY

Antimicrobial resistance in the respiratory microbiota of people with cystic fibrosis

(2014) Laura J Sherrard et al.   LANCET

A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056

(2012) Mariano A. Scorciapino et al.   BIOPHYSICAL JOURNAL

Characterization of biofilm-like structures formed by Pseudomonas aeruginosa in a synthetic mucus medium

(2012) Cecily L Haley et al.   BMC MICROBIOLOGY

Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia

(2012) Arianna Pompilio et al.   BMC MICROBIOLOGY

Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype

(2012) Jenny K. Gustafsson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

EDTA chelation reappraisal following new clinical trials and regular use in millions of patients: review of preliminary findings and risk/benefit assessment

(2012) Tammy Born et al.   TOXICOLOGY MECHANISMS AND METHODS

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung

(2012) Sebastian Kirchner et al.   Jove-Journal of Visualized Experiments

Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

(2011) Morten Alhede et al.   PLoS One

Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis

(2010) L. R. Mulcahy et al.   JOURNAL OF BACTERIOLOGY

Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputum

(2010) C. Fung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Iron-binding compounds impair Pseudomonas aeruginosa biofilm formation, especially under anaerobic conditions

(2009) C. Y. O'May et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Dynamic Structure of Disulfide-Removed Linear Analogs of Tachyplesin-I in the Lipid Bilayer from Solid-State NMR†

(2007) Tim Doherty et al.   BIOCHEMISTRY

Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta defensin 3

(2007) Giuseppantonio Maisetta et al.   PEPTIDES