Article
Cardiac & Cardiovascular Systems
Richard L. Weinberg, Robert D. Brook, Melvyn Rubenfire, Kim A. Eagle
Summary: Omega-3 polyunsaturated fatty acids play a key role in heart-healthy diet, and can be obtained through fatty fish consumption or fish oil supplementation. They not only treat hypertriglyceridemia, but also prevent cardiovascular events, with additional benefits such as reducing inflammation and improving plaque stability.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Environmental Sciences
Priyanshi Sikka, Tapan Behl, Sanchay Sharma, Aayush Sehgal, Saurabh Bhatia, Ahmed Al-Harrasi, Sukhbir Singh, Neelam Sharma, Lotfi Aleya
Summary: Ω-3 fatty acids are recognized for their benefits on physical and mental health, primarily obtained from fish and fish products. Adequate intake of Ω-3 fatty acids can improve brain function and neuronal function, reduce depressive symptoms, and have fewer side effects compared to antidepressants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Nutrition & Dietetics
Maja Tomczyk, Jeffery L. Heileson, Miroslaw Babiarz, Philip C. Calder
Summary: Fatty fish and certain species of algae are the only natural sources of EPA and DHA, which have various beneficial effects for athletes. Due to limited intake and fluctuating content, athletes may consider using supplements to ensure sufficient EPA and DHA levels.
Article
Nutrition & Dietetics
Maria Dolores Mesa, Fernando Gil, Pablo Olmedo, Angel Gil
Summary: This study aims to estimate the amount of n-3 LC-PUFA provided by commonly consumed fishes, shrimps, and mollusks, to conduct a risk-benefit analysis of fish consumption. Consuming 2-3 servings of a variety of fishery products per week can help meet recommended n-3 LC-PUFA levels while maintaining a balance to avoid potential risks from contaminants.
Article
Nutrition & Dietetics
Roberta Dourado Cavalcante da Cunha de Sa, Jussara de Jesus Simao, Viviane Simoes da Silva, Talita Mendes de Farias, Maysa Mariana Cruz, Vitor Jaco Antraco, Lucia Armelin-Correa, Maria Isabel Alonso-Vale
Summary: This study found that different ratios of EPA and DHA have different impacts on adipose tissue metabolism, with fish oil rich in EPA instead of DHA effectively reversing changes induced by obesity.
Article
Biochemistry & Molecular Biology
Ines Drenjancevic, Jan Pitha
Summary: In addition to proven medications, omega-3 polyunsaturated fatty acids (n-3 PUFAs) are considered to have additive effects on cardiovascular health. They influence the cardiovascular system through various mechanisms, including effects on metabolism, inflammation, thrombosis, and direct effects on cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Juan Li, Meiru Mao, Jiacheng Li, Ziteng Chen, Ying Ji, Jianglong Kong, Zhijie Wang, Jiaxin Zhang, Yujiao Wang, Wei Liang, Haojun Liang, Linwen Lv, Qiuyang Liu, Ruyu Yan, Hui Yuan, Kui Chen, Yanan Chang, Guogang Chen, Gengmei Xing
Summary: This study assessed the effects of omega-3 fatty acids on alleviating inflammation and lung injury induced by PM2.5 inhalation exposure. It was found that oral administration of DHA and EPA effectively restored normal inflammatory cytokine levels and reduced lung parenchymal lesions in mice exposed to PM2.5.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Sport Sciences
Jon-Kyle Davis, Eric C. Freese, Anthony S. Wolfe, Steven A. Basham, Kimberly M. W. Stein
Summary: The study evaluated the omega-3 PUFA blood concentrations, dietary, and supplement intake of 119 professional basketball players, with many players having insufficient fish consumption per week and only a few players supplementing with omega-3 PUFA.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2021)
Article
Nutrition & Dietetics
Sebastian Andone, Lenard Farczadi, Silvia Imre, Zoltan Bajko, Anca Motataianu, Smaranda Maier, Laura Barcutean, Rodica Balasa
Summary: Stroke prevention is crucial and can be achieved by addressing risk factors, particularly modifiable lifestyle factors. Our study investigated the relationship between ischemic-stroke risk factors and fatty acids in 274 patients using a prospective observational study. We found that age, sex, smoking, atrial fibrillation, dyslipidemia, and previous stroke history were directly related to fatty acids. Smoking had the most significant negative impact, while dyslipidemia and atrial fibrillation had a positive correlation, particularly in female patients and those with recurrent strokes. Better management of risk factors could improve fatty-acid profiles and the balance of Omega-3 and Omega-6 in ischemic stroke patients.
Article
Nutrition & Dietetics
Ayu Kasamatsu, Hiroshi Tachimoto, Mitsuyoshi Urashima
Summary: This study investigated the associations between maternal dietary habits, infant feeding patterns, and serum levels of DHA and other LCPUFAs in 5-6-month-old infants in Japan. It found that frequent consumption of Blue-back fish and/or White fish by lactating mothers, as well as prioritizing breastfeeding, can effectively increase infants' serum DHA levels.
Article
Nutrition & Dietetics
Bojung Seo, Keming Yang, Ka Kahe, Abrar A. Qureshi, Andrew T. Chan, Immaculata De Vivo, Eunyoung Cho, Edward L. Giovannucci, Hongmei Nan
Summary: This study suggests that higher intakes of DHA and consumption of canned tuna are associated with longer leukocyte telomere length (LTL) in US males.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Stephen W. Farrell, Laura F. DeFina, Nathan L. Tintle, David Leonard, Kenneth H. Cooper, Carolyn E. Barlow, William L. Haskell, Andjelka Pavlovic, William S. Harris
Summary: Both this study and a meta-analysis of similar studies found no evidence to suggest that consuming n-3 PUFA-rich fish or using fish oil supplements affects the risk of prostate cancer.
Review
Nutrition & Dietetics
Manoj Kumar, Namrata Pal, Poonam Sharma, Manoj Kumawat, Devojit Kumar Sarma, Bilkees Nabi, Vinod Verma, Rajnarayan R. Tiwari, Swasti Shubham, Bahram Arjmandi, Ravinder Nagpal
Summary: This paper provides insights into the potential role of omega-3 fatty acids in the management of Type-2 diabetes mellitus (T2DM) by influencing gut dysbiosis. By reviewing and discussing the molecular mechanisms and signaling pathways, the paper explores the associations between omega-3 fatty acids, gut dysbiosis, and the pathophysiology of T2DM and its related comorbidities. Moreover, the significance of gut microbiota in T2DM prevention and treatment is highlighted along with the potential of omega-3 fatty acids to positively modulate gut microbiota, leading to the discovery of new targets and therapeutic strategies for T2DM.
Review
Psychiatry
Diego Chambergo-Michilot, Ana Branez-Condorena, Ian Falvy-Bockos, Josmel Pacheco-Mendoza, Vicente A. Benites-Zapata
Summary: The study synthesized evidence from four RCTs on the efficacy of adding omega-3 supplementation to continuous sertraline therapy in adults with depression. Results showed no significant impact on outcomes, with very low certainty of the evidence. Recommendations on providing supplementation remain inconclusive due to insufficient evidence.
PSYCHIATRY RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Sarah Fathima, Ekatherine Prokopiou, Tassos Georgiou
Summary: Diabetic retinopathy is a common complication of type 2 Diabetes Mellitus that can lead to vision loss. The use of anti-oxidants for treatment has not been strongly supported by data. Omega-3 fatty acids have shown promising effects on cardiovascular health and their anti-oxidative and anti-inflammatory properties make them potential therapeutic agents for diabetic retinopathy. However, more clinical trials are needed to fully understand their benefits.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2023)
Article
Multidisciplinary Sciences
Barbara J. Meyer, Mitchell K. Byrne, Carole Collier, Natalie Parletta, Donna Crawford, Pia C. Winberg, David Webster, Karen Chapman, Gayle Thomas, Jean Dally, Marijka Batterham, Ian Farquhar, Anne-Marie Martin, Luke Grant
Correction
Multidisciplinary Sciences
Barbara J. Meyer, Mitchell K. Byrne, Carole Collier, Natalie Parletta, Donna Crawford, Pia C. Winberg, David Webster, Karen Chapman, Gayle Thomas, Jean Dally, Marijka Batterham, Ian Farquhar, Anne-Marie Martin, Luke Grant
Article
Public, Environmental & Occupational Health
Dorota M. Zarnowiecki, Natalie Parletta, James Dollman
PUBLIC HEALTH NUTRITION
(2016)
Letter
Psychiatry
Jerome Sarris, Alan C. Logan, Tasnime N. Akbaraly, G. Paul Amminger, Vicent Balanza-Martinez, Marlene P. Freeman, Joseph Hibbeln, Yutaka Matsuoka, David Mischoulon, Tetsuya Mizoue, Akiko Nanri, Daisuke Nishi, Natalie Parletta, Drew Ramsey, Julia J. Rucklidge, Almudena Sanchez-Villegas, Andrew Scholey, Kuan-Pin Su, Felice N. Jacka
Letter
Pediatrics
Barbara J. Meyer, Mitchell Byrne, Natalie Parletta, Rachel Gow, Joseph R. Hibbeln
JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
(2016)
Article
Neurosciences
R. S. Opie, C. Itsiopoulos, N. Parletta, A. Sanchez-Villegas, T. N. Akbaraly, A. Ruusunen, F. N. Jacka
NUTRITIONAL NEUROSCIENCE
(2017)
Article
Biochemistry & Molecular Biology
Natalie Parletta, Dorota Zarnowiecki, Jihyun Cho, Amy Wilson, Nicholas Procter, Andrea Gordon, Svetlana Bogomolova, Kerin O'Dea, John Strachan, Matt Ballestrin, Andrew Champion, Barbara J. Meyer
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
(2016)
Article
Psychiatry
Natalie Parletta, Yousef Aljeesh, Bernhard T. Baune
FRONTIERS IN PSYCHIATRY
(2016)
Article
Neurosciences
Natalie Parletta, Dorota Zarnowiecki, Jihyun Cho, Amy Wilson, Svetlana Bogomolova, Anthony Villani, Catherine Itsiopoulos, Theo Niyonsenga, Sarah Blunden, Barbara Meyer, Leonie Segal, Bernhard T. Baune, Kerin O'Dea
NUTRITIONAL NEUROSCIENCE
(2019)
Article
Psychology, Developmental
Catherine M. Milte, Natalie Parletta, Jonathan D. Buckley, Alison M. Coates, Ross M. Young, Peter R. C. Howe
JOURNAL OF ATTENTION DISORDERS
(2015)
Article
Multidisciplinary Sciences
Natalie Parletta, Theophile Niyonsenga, Jacques Duff
Article
Neurosciences
Leonie Segal, Asterie Twizeyemariya, Dorota Zarnowiecki, Theo Niyonsenga, Svetlana Bogomolova, Amy Wilson, Kerin O'Dea, Natalie Parletta
NUTRITIONAL NEUROSCIENCE
(2020)
Article
Nutrition & Dietetics
Colin H. Cortie, Mitchell K. Byrne, Carole Collier, Natalie Parletta, Donna Crawford, Pia C. Winberg, David Webster, Karen Chapman, Gayle Thomas, Jean Dally, Marijka Batterham, Anne Marie Martin, Luke Grant, Barbara J. Meyer
Article
Criminology & Penology
Mitchell K. Byrne, Natalie Parletta, David G. Webster, Marijka Batterham, Barbara J. Meyer
PSYCHIATRY PSYCHOLOGY AND LAW
(2015)