Article
Geriatrics & Gerontology
Erwin Stolz, Emiel O. Hoogendijk, Hannes Mayerl, Wolfgang Freidl
Summary: Various studies have shown consistent associations between current FI levels, baseline FI levels, and mortality. Additionally, individuals with steeper FI growth have a higher risk of mortality.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Geriatrics & Gerontology
Yun-Ting Huang, Andrew Steptoe, Li Wei, Paola Zaninotto
Summary: This study investigated the association between different levels of polypharmacy and mortality among older adults. The results showed that both polypharmacy and heightened polypharmacy were related to all-cause mortality and cardiovascular disease deaths. Heightened polypharmacy was also related to cancer mortality. The study suggests that greater attention to polypharmacy in general for older people may reduce adverse effects and improve their health.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Review
Food Science & Technology
Noushin Mohammadifard, Marjan Mansourian, Somayyeh Firouzi, Marzieh Taheri, Fahimeh Haghighatdoost
Summary: This study found that an increased intake of dietary carbohydrates is associated with a higher risk of CVD events, especially in women, but not with CVD mortality or CHD events. Higher carbohydrate intake is also linked to an increased risk of stroke, with no significant association found in men.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Immunology
Hayoung Choi, Kyungdo Han, Jin-Hyung Jung, Sang Hyun Park, Sang Hyuk Kim, Hyung Koo Kang, Jang Won Sohn, Dong Wook Shin, Hyun Lee
Summary: The long-term mortality risk in this study was significantly higher in tuberculosis survivors than those in the matched controls, even after adjusting for potential confounders, including behavior habits, income level, body mass index, and comorbidities.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Nutrition & Dietetics
Shaohua Zhao, Shaohua Wang, Xiaorong Yang, Lin Shen
Summary: This study aimed to investigate the independent and combined relationship between trace elements concentrations and all-cause mortality. The results showed an association between multiple trace elements and all-cause mortality, suggesting the need for strengthening the surveillance and management of trace elements.
FRONTIERS IN NUTRITION
(2023)
Article
Pharmacology & Pharmacy
Joyce S. Tsuji, Kristin P. Lennox, Heather N. Watson, Ellen T. Chang
Summary: The assessment of epidemiological studies on low-level arsenic should take into account arsenic metabolism, confounding factors, and potential bias in dose-response relationship. The presence of multiple factors can influence the risk estimate and apparent dose-response in the low-dose range.
Review
Sport Sciences
Leandro Garcia, Matthew Pearce, Ali Abbas, Alexander Mok, Tessa Strain, Sara Ali, Alessio Crippa, Paddy C. Dempsey, Rajna Golubic, Paul Kelly, Yvonne Laird, Eoin McNamara, Samuel Moore, Thiago Herick de Sa, Andrea D. Smith, Katrien Wijndaele, James Woodcock, Soren Brage
Summary: This study aims to estimate the dose-response associations between non-occupational physical activity and chronic disease outcomes and mortality. The results show that even small increases in non-occupational physical activity can significantly reduce the risk of various diseases and mortality compared to being inactive.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Review
Food Science & Technology
Asma Kazemi, Sepideh Soltani, Zeinab Mokhtari, Tauseef Khan, Mahdieh Golzarand, Elham Hosseini, Ahmad Jayedi, Soraiya Ebrahimpour, Masoumeh Akhlaghi
Summary: We conducted a systematic review and meta-analysis to summarize the associations between food sources of fructose and cardiovascular diseases (CVD), cancer, and all-cause mortality risk. The findings indicated that fruit, breakfast cereals, sweets, and yogurt were associated with lower risk of all-cause and/or CVD mortality, while sugar-sweetened beverages (SSBs) had a harmful relationship with all-cause and CVD mortality. Fruit intake also had an inverse link with cancer mortality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Editorial Material
Oncology
Richard C. Wender
Summary: Individuals with more social determinants of poor health are at higher risk for cancer-related death. This article presents a roadmap to reduce the devastating effects of social factors.
Article
Oncology
Yuting Li, Li-liangzi Guo, Kaiyin He, Changbing Huang, Shaohui Tang
Summary: The consumption of sugary beverages, including sugar-sweetened beverages and fruit juice, may increase the overall risk and mortality of cancer, particularly for breast cancer, hepatocellular carcinoma, colorectal cancer, and prostatic cancer.
Review
Food Science & Technology
Sina Naghshi, Mohammad Naemi, Omid Sadeghi, Manije Darooghegi Mofrad, Mehrasa Moezrad, Leila Azadbakht
Summary: This study aimed to investigate the association between calcium intake and mortality risk. The findings suggested that moderate intake of total and dietary calcium were inversely associated with mortality risk, while supplemental calcium intake showed no significant association. Nonlinear relationships were observed between calcium intake and all-cause, CVD, and cancer mortality risk.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Nutrition & Dietetics
Niloofar Eshaghian, Neda Heidarzadeh-Esfahani, Hakimeh Akbari, Gholamreza Askari, Omid Sadeghi
Summary: This study conducted a dose-response meta-analysis to summarize the association between fish intake and prostate cancer risk. A total of 25 prospective cohort studies were included, involving 1,216,474 men. The findings indicated a negative correlation between fish intake and the incidence and mortality of prostate cancer.
FRONTIERS IN NUTRITION
(2023)
Article
Public, Environmental & Occupational Health
Xianmin Wang, Yupeng Luo, Tingting Chen, Kui Zhang
Summary: The meta-analysis suggests that post-diagnosis, but not pre-diagnosis, low-dose aspirin use may reduce cancer-specific mortality, especially in the case of digestive tract cancers.
JOURNAL OF PUBLIC HEALTH
(2021)
Review
Nutrition & Dietetics
Nikan Zargarzadeh, Seyed Mohammad Mousavi, Heitor O. Santos, Dagfinn Aune, Shirin Hasani-Ranjbar, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This study examined the potential dose-response relationship between legume consumption and mortality rates in the general population. The results showed that higher legume intake was associated with a reduced risk of all-cause and stroke mortality, but there was no significant association with cardiovascular disease, coronary heart disease, and cancer mortality.
ADVANCES IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Seyed Mohammad Mousavi, Nikan Zargarzadeh, Somaye Rigi, Emma Persad, Ana Beatriz Pizarro, Shirin Hasani-Ranjbar, Bagher Larijani, Walter C. Willett, Ahmad Esmaillzadeh
Summary: The study found that higher egg consumption was not associated with mortality from all causes, cardiovascular disease, coronary heart disease, stroke, or respiratory disease. However, it was associated with an increased risk of cancer mortality. Each additional egg per week consumption was associated with a 2% and 4% increased risk of all-cause and cancer mortality, respectively. The certainty of the evidence was rated as low to moderate.
ADVANCES IN NUTRITION
(2022)
Correction
Environmental Sciences
Nobuhiko Ban, Enora Clero, Ludovic Vaillant, Wei Zhang, Nobuyuki Hamada, Dale Preston, Dominique Laurier
JOURNAL OF RADIOLOGICAL PROTECTION
(2022)
Review
Neurosciences
Julie Lopes, Klervi Leuraud, Dmitry Klokov, Christelle Durand, Marie-Odile Bernier, Clemence Baudin
Summary: A systematic review and meta-analysis of epidemiological studies suggest that low-to-moderate ionizing radiation exposure in adulthood may increase the risk of non-cancerous central nervous system diseases, such as cerebrovascular diseases and Parkinson's disease.
Article
Biology
Lydia B. Zablotska, Ljubica Zupunski, Klervi Leuraud, Julie Lopes, Joshua Hinkle, Tyler Pugeda, Thomas Delgado, John Olschowka, Jacqueline Williams, M. Kerry O'Banion, John D. Boice, Sarah S. Cohen, Michael T. Mumma, Lawrence T. Dauer, Richard A. Britten, Samuel Stephenson, Klervi Leuraud, Julie Lopes, Joshua Hinkle, Tyler Pugeda, Thomas Delgado, John Olschowka, Jacqueline Williams, M. Kerry O'Banion, John D. Boice, Sarah S. Cohen, Michael T. Mumma, Lawrence T. Dauer, Richard. A. Britten, Samuel Stephenson
Summary: This article summarizes a virtual symposium on the radiation risks of the central nervous system. It discusses the potential neurological complications and psychological consequences of repeated low-dose radiation exposure, emphasizing the need for further research in this area. The symposium highlights new directions for studying mental health disorders, neurodegenerative conditions, and cognitive impairment related to radiation exposure, including occupational exposures and exposures to galactic cosmic rays.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2023)
Article
Oncology
Michael Hauptmann, Graham Byrnes, Elisabeth Cardis, Marie-Odile Bernier, Maria Blettner, Jeremie Dabin, Hilde Engels, Tore S. Istad, Christoffer Johansen, Magnus Kaijser, Kristina Kjaerheim, Neige Journy, Johanna M. Meulepas, Monika Moissonnier, Cecile Ronckers, Isabelle Thierry-Chef, Lucian Le Cornet, Andreas Jahnen, Roman Pokora, Magda Bosch de Basea, Jordi Figuerola, Carlo Maccia, Arvid Nordenskjold, Richard W. Harbron, Choonsik Lee, Steven L. Simon, Amy Berrington de Gonzalez, Joachim Schuz, Ausrele Kesminiene
Summary: The European EPI-CT study aims to assess the risk of brain cancer from CT examinations in children and young adults. Using data from nine European countries, the study found a significant dose-response relationship between CT-related radiation exposure and brain cancer.
Editorial Material
Public, Environmental & Occupational Health
Mary K. Schubauer-Berigan, David B. Richardson, Matthew P. Fox, Lin Fritschi, Irina Guseva Canu, Neil Pearce, Leslie Stayner, Amy Berrington de Gonzalez
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Oncology
Olivier Laurent, Eric Samson, Sylvaine Caer-Lorho, Lucie Fournier, Dominique Laurier, Klervi Leuraud
Summary: Cohort studies of nuclear workers are crucial for studying the health effects of long-term exposures to low doses of ionizing radiation. This study found a significant association between exposure to radiation and increased risk of death from leukaemia and dementia. The association with dementia should be further investigated. Continued follow-up and pooled analyses with similar cohorts will improve the precision of risk estimates.
Editorial Material
Environmental Sciences
Dominique Laurier, Yann Billarand, Dmitry Klokov, Klervi Leuraud
Summary: The use of the LNT model in radiation protection is still debated, but recent research in radiobiology and epidemiology has reinforced our scientific understanding of cancer risks at low doses. In radiobiology, early carcinogenic events show linear responses to doses as low as 10 mGy, while epidemiological studies indicate excess cancer risks at dose levels of 100 mGy or less. Overall, the LNT model does not substantially overestimate risks at low doses, and current scientific knowledge does not contradict its use in the radiological protection system.
JOURNAL OF RADIOLOGICAL PROTECTION
(2023)
Article
Public, Environmental & Occupational Health
Ankura Singh, Rachel Zeig-Owens, Madeline Cannon, Mayris P. Webber, David G. Goldfarb, Robert D. Daniels, David J. Prezant, Paolo Boffetta, Charles B. Hall
Summary: This study compared mortality rates between World Trade Center (WTC)-exposed FDNY firefighters and similarly healthy, non-WTC-exposed/non-FDNY firefighters, and compared mortality in each cohort with the general population. The results showed that both cohorts of firefighters had lower all-cause mortality compared to the general population, and WTC-exposed firefighters had lower mortality rates compared to non-WTC-exposed firefighters.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Kaitlin Kelly-Reif, Stephen J. Bertke, Estelle Rage, Paul A. Demers, Nora Fenske, Veronika Deffner, Michaela Kreuzer, Jonathan Samet, Mary K. Schubauer-Berigan, Ladislav Tomasek, Lydia B. Zablotska, Charles Wiggins, Dominique Laurier, David B. Richardson
Summary: This study is the largest and most up-to-date pooled study of uranium miners, involving 7 cohorts of male uranium miners with 7754 lung cancer deaths and 4.3 million person-years of follow-up. The study found a linear exposure-response relationship between cumulative radon exposure and lung cancer mortality, which is modified by temporal and exposure factors.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Julie Lopes, Clemence Baudin, Juliette Feuardent, Herve Roy, Sylvaine Caer-Lorho, Klervi Leuraud, Marie-Odile Bernier
Summary: Medical personnel in France are occupationally exposed to ionizing radiation, but no study has been conducted to investigate the health risks associated with this exposure. The ORICAMs cohort is a nationwide French longitudinal study that aims to assess the risk of radiation-associated cancer and non-cancer mortality in medical workers. The cohort includes workers monitored for ionizing radiation exposure from 2002 to 2012. Initial analysis shows that the mortality rate among these workers is significantly lower than the national reference rates, but further research is needed to establish a potential relationship between occupational exposure and mortality risk.
Review
Public, Environmental & Occupational Health
Nathan L. DeBono, Robert D. Daniels, Laura E. Beane Freeman, Judith M. Graber, Johnni Hansen, Lauren R. Teras, Tim Driscoll, Kristina Kjaerheim, Paul A. Demers, Deborah C. Glass, David Kriebel, Tracy L. Kirkham, Roland Wedekind, Adalberto M. Filho, Leslie Stayner, Mary K. Schubauer-Berigan
Summary: This study is a meta-analysis of the association between occupational exposure as a firefighter and cancer. The results show that there is epidemiological evidence supporting a causal relationship between being a firefighter and certain cancers, but challenges remain in exposure assessment, confounding, and medical surveillance bias.
SAFETY AND HEALTH AT WORK
(2023)
Article
Medicine, General & Internal
David B. Richardson, Klervi Leuraud, Dominique Laurier, Michael Gillies, Richard Haylock, Kaitlin Kelly-Reif, Stephen Bertke, Robert D. Daniels, Isabelle Thierry-Chef, Monika Moissonnier, Ausrele Kesminiene, Mary K. Schubauer-Berigan
Summary: This multinational study evaluated the association between protracted low dose exposure to ionising radiation and the risk of cancer. The results showed that for every 1 Gy increase in cumulative dose, the mortality rate of solid cancer increased by 52%, with the association potentially being more significant in the low dose range. These findings are of vital importance in strengthening radiation protection.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Nuclear Science & Technology
Isabelle Thierry-Chef, Beate Timmermann, Neige Journy, Marie-Odile Bernier, Richard McNally, Jeremie Dabin, Lorenzo Brualla, Siamak Haghdoost, Adelaida Sarukhan, Karin Haustermans, Inge De Wit, Sofie Isebaert, Yasmin Lassen-Ramshad, Louise Tram Henriksen, Morten Hoyer, Laura Toussaint, Guillaume Boissonnat, Juliette Thariat, Charlotte Demoor-Goldschmidt, Nadia Haddy, Stephanie Bolle, Brice Fresneau, Amel Belhout, Steffen Dreger, Hajo Zeeb, Maria Grazia Andreassi, Jonica Campolo, Eugenio Picano, Andreas Jahnen, Cecile Ronckers, John H. Maduro, Kristina Kjaerheim, Gaute Dohlen, Trude Eid Robsahm, Hilde M. Olerud, Utheya Salini Thevathas, Susmita Afroz, Bjorn Helge Osteras, Uwe Schneider, Linda Walsh, Agnes Dumas, Angela Jackson, Estelle Rage, Marijke De Saint-Hubert, Richard Hardy, Christian Baeumer, Theresa Steinmeier, Suzan Botzenhardt, Martina Wette, Rodney Ortiz, Vadim Chumak
Summary: The use of ionising radiation in medical procedures has greatly benefited paediatric patients, but the long-term health effects need to be evaluated. The HARMONIC project aims to understand the increased risk of cancer and non-cancer effects after exposure to radiation in children with cancer and cardiac defects. It investigates potential endocrine dysfunction, cardiovascular and neurovascular damage, health-related quality of life, and risks of second primary cancers. The project also develops software tools for dose reconstruction and builds a biobank to identify biomarkers of radiation-induced adverse health effects.
EPJ NUCLEAR SCIENCES & TECHNOLOGIES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Clemence Baudin, Blandine Vacquier, Guillemette Thin, Lamine Chenene, Joel Guersen, Isabelle Partarrieu, Martine Louet, Hubert Ducou Le Pointe, Stephanie Mora, Catherine Verdun-Esquer, Juliette Feuardent, Frederic Rousseau, Herve Roy, Lynda Bensefa-Colas, Louis Boyer, Marie-Odile Bernier
Summary: Health workers in France exposed to ionizing radiation account for more than 50% of all workers exposed to man-made radiation. This study aimed to evaluate and characterize the trends in radiation exposure among health workers in France between 2009 and 2019. The study found that the average exposure of health workers decreased over the past decade, but there were discrepancies in trends according to professions, departments, hospitals, and gender.
EUROPEAN RADIOLOGY
(2023)