Article
Biochemistry & Molecular Biology
Soo-Il Kim, Sin-Hye Park, Woojin Na, Yong Chul Shin, Moon-Sik Oh, Young Eun Sim, Yulong Zheng, Ae Hyang Kim, Il-Jun Kang, Young-Hee Kang
Summary: Pangasius hypophthalmus fish skin collagen hydrolysates (fsCH) can retard postmenopausal osteoporosis by inhibiting bone loss and enhancing bone density.
Review
Biology
Mala Nurilmala, Heny Suryamarevita, Hanifah Husein Hizbullah, Agoes M. Jacoeb, Yoshihiro Ochiai
Summary: The utilization of fishery byproducts is important for increasing their commercial values and preventing environmental pollution. Preparing collagen and gelatin from fish skin meets the demand for halal products and offers a satisfactory alternative to bovine sources.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Min-Kyung Kang, Dong-Yeon Kim, Hyeongjoo Oh, Soo-Il Kim, Su-Yeon Oh, Woojin Na, Sin-Hye Park, Kyungho Park, Jun-Il Kim, Ae-Hyang Kim, Young-Hee Kang
Summary: Collagen hydrolysates can mitigate skin aging caused by UV radiation by promoting moisture retention and reducing wrinkle formation. The study showed that fsCH can improve skin issues in UV-B exposed mice and combat skin aging by restoring protein expression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Dafne Wilhelm, Alison Wurtz, Hanane Abouelfarah, Guillaume Sanchez, Catherine Bui, Jean -Baptiste Vincourt
Summary: Collagen, the most abundant organic compound in vertebrate organisms, undergoes post-translational modifications that determine the mechanical properties of connective tissues. The hydroxylation of collagen is catalyzed by the enzyme Prolyl-4hydroxylases (P4HA1-3), with P4HA2 playing a key role in tendon-specific hydroxylation. This tissue-specific regulation of P4HA2 expression contributes to the unique collagen assembly in tendons.
Article
Chemistry, Applied
Zengliu Song, Huanming Liu, Liwen Chen, Leilei Chen, Chunxia Zhou, Pengzhi Hong, Chujin Deng
Summary: The study showed that fermentation pretreatment for collagen extraction is a viable alternative, with slightly higher yields compared to chemical treatment and similar structures and biochemical properties.
Article
Biophysics
Xue Song, Zhaoxuan Li, Yanyan Li, Hu Hou
Summary: Aquatic collagens have gained attention as alternative sources of mammalian collagen due to their low-cost, low-antigenicity, biocompatibility, and biodegradability. A study examined pepsin-soluble collagens from the skins of Oreochromis mossambicus and Gadus macrocephalus, revealing their potential applications in tissue engineering as biomedical materials. The collagens showed similar triple helical structures and good biocompatibility, and promoted cell proliferation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Dermatology
Xinyue Pu, Yan Qu
Summary: This study investigated the potential mechanism and delayed effect of tilapia skin collagen on skin aging in mice. It was found that tilapia skin collagen had a significant impact on improving skin aging, including increasing dermal thickness, improving skin moisture content, and enhancing antioxidant activity. Furthermore, the anti-aging effect of tilapia skin collagen was dose-dependent.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Nataly Reategui-Pinedo, David Salirrosas, Linda Sanchez-Tuesta, Claudio Quinones, Segundo R. Jauregui-Rosas, Gabriela Barraza, Angelita Cabrera, Carmen Ayala-Jara, Renata Miliani Martinez, Andre Rolim Baby, Zulita Adriana Prieto
Summary: The by-products of tilapia farming have been found to be a potential source of collagen for dermocosmetics and pharmaceutical products. Collagen characteristics were studied in three strains of tilapia: red YY males, XX gray females, and the F1 progeny. The F1 progeny showed the most stable and advantageous characteristics for collagen extraction. Evaluations of the triple helix structure showed similar results between the strains and between ages in the adult form of F1. The skin of tilapia in adult form is recommended for collagen extraction sustainably for up to 24 months of age.
Article
Biochemistry & Molecular Biology
Eduardo P. Milan, Murilo A. Rodrigues, Virginia C. A. Martins, Ana M. G. Plepis, Thomas Fuhrmann-Lieker, Marilia M. Horn
Summary: Collagen/mangosteen porous scaffolds were used to mimic a potential hard tissue substitute, with phosphorylation and mangosteen addition enhancing the mineralization process. Successful mineralization was achieved while maintaining the porous structure of the scaffolds.
Article
Engineering, Biomedical
Hongqian Lv, Nan Gao, Qixin Zhou, Yan Wang, Guixia Ling, Peng Zhang
Summary: This study develops rapidly dissolving microneedles (DMNs) using hydrolyzed collagen (HC) as the main raw material, which can deliver collagen to the skin in a simple and minimally invasive way. The DMNs dissolve completely in the skin within 15 min and release drug within approximately 8 h, without causing toxicity or irritation. The drug-loaded DMNs overcome the drawbacks of traditional methods, enabling efficient and safe treatment. The successful preparation and research of HC DMNs have innovative and practical significance in the field of transdermal drug delivery.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Applied
Yu Iwasaki, Mizuho Nakatogawa, Ayaka Shimizu, Yoshio Sato, Yasutaka Shigemura
Summary: This study demonstrated that gelatin ingestion led to significant increases in prolyl-hydroxyproline and hydroxyprolyl-glycine levels in the plasma. Low molecular weight gelatin hydrolysate was more effective in enhancing the concentrations of these peptides.
Article
Chemistry, Multidisciplinary
Araceli Lino-Sanchez, Virginia Gonzalez-Velez, Marisela Velez, Julia Aguilar-Pliego
Summary: In this study, we successfully extracted and characterized natural collagen from fish scales. The obtained collagen had high denaturation temperatures and hydroxyproline contents, making it a valuable alternative for biomedical applications.
Article
Biochemistry & Molecular Biology
K. Sivaraman, C. Shanthi
Summary: This study evaluated the therapeutic effects of purified hydrolysate fraction of fish skin collagen from Clarias batrachus and Pangasius pangasius in inflammatory bowel disease. The results showed that the hydrolysate fraction could counter TNF-alpha induced barrier dysfunction and improve clinical signs of colitis in mice.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Fisheries
Haoji Guo, Qianhui Zhang, Xin Liu, Haoran Zhang, Shuqi Wang, Xiaobo Wen, Fan Lin
Summary: Collagen, as a functional protein, has a high market demand and is widely used in the food, cosmetic, and biomedicine industries. Swim bladder is considered an ideal source for collagen production due to its high collagen content and low risk of infectious pathogens. This study investigated the molecular mechanism of how dietary hydroxyproline (Hyp) promotes collagen deposition in the swim bladder of Nibea coibor. The results showed that Hyp up-regulated collagen synthesis-related genes and affected the amino acid profile in swim bladder cells. These findings provide new insights into the regulatory mechanism of Hyp on collagen deposition and can contribute to the development of nutritional strategies for collagen production from aquatic species.
Article
Biochemistry & Molecular Biology
Jaechul Yoon, Dogeon Yoon, Hyeongjin Lee, JiUn Lee, SeoYul Jo, Dohern Kym, Haejun Yim, Jun Hur, Wook Chun, GeunHyung Kim, Yong Suk Cho
Summary: This study compared the wound healing ability of acellular fish skin graft with bovine collagen skin graft. It found that the acellular fish skin graft had faster healing compared to the bovine collagen skin graft, possibly due to the synergistic effect of its unique biophysical structure and bioactive components.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Engineering, Biomedical
Agnieszka Marcinkowska, Marlena Gauza-Wlodarczyk, Leszek Kubisz, Wieslaw Hedzelek
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2017)
Article
Materials Science, Biomaterials
Marlena Gauza-Wlodarczyk, Leszek Kubisz, Slawornir Mielcarek, Dariusz Wlodarczyk
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2017)
Article
Physics, Multidisciplinary
M. Gauza, L. Kubisz
ACTA PHYSICA POLONICA A
(2010)
Article
Materials Science, Ceramics
Marlena Gauza, Leszek Kubisz
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2011)
Article
Plant Sciences
Roman Holubowicz, Leszek Kubisz, Marlena Gauza, Yilin Tong, Dorota Hojan-Jezierska
NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA
(2014)
Article
Physics, Multidisciplinary
L. Kubisz, R. Holubowicz, M. Gauza, H. Li, D. Hojan-Jezierska, F. Jaroszyk
ACTA PHYSICA POLONICA A
(2012)
Article
Physics, Multidisciplinary
M. Gauza, L. Kubisz
ACTA PHYSICA POLONICA A
(2012)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marlena Gauza, Leszek Kubisz
POLISH JOURNAL OF MEDICAL PHYSICS AND ENGINEERING
(2009)
Article
Psychology, Biological
Piotr Jaskowski, Dariusz Wlodarczyk
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
(2006)
Article
Psychology, Experimental
P Jaskowski, D Wlodarczyk
PERCEPTUAL AND MOTOR SKILLS
(2005)
Article
Psychology, Experimental
D Wlodarczyk, P Jaskowski
PERCEPTUAL AND MOTOR SKILLS
(2002)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)