Article
Multidisciplinary Sciences
Hiroyuki Yamamoto, Haruna Akiba, Hiroshi Inagawa, Yasusei Okada
Summary: This is a rare and difficult-to-diagnose case of isolated right ventricular Takotsubo cardiomyopathy. The patient presented with acute right ventricular failure, progressing to cardiogenic shock requiring intensive treatment. Conflicting echocardiographic findings of right ventricular asynergy with right ventricular enlargement despite normal left ventricular wall motion and mild tricuspid regurgitation led to the correct diagnosis. Finally, the patient showed complete recovery with normalization of cardiac structure and function.
Review
Cardiac & Cardiovascular Systems
Fawzi Zghyer, W. Savindu Pasan Botheju, Joshua E. Kiss, Erin D. Michos, Mary C. Corretti, Monica Mukherjee, Allison G. Hays
Summary: Stress cardiomyopathy is a reversible syndrome caused by myocardial injury, usually occurring in response to a stressful event. Neurocardiogenic mechanisms may play an important role in its pathophysiology. Although initially considered relatively benign, research has brought attention to its association with cardiovascular complications.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Critical Care Medicine
Ryan Ruiyang Ling, Kollengode Ramanathan, Wynne Hsing Poon, Chuen Seng Tan, Nicolas Brechot, Daniel Brodie, Alain Combes, Graeme MacLaren
Summary: The majority of adult patients with septic shock and severe sepsis-induced myocardial depression can survive when treated with VA ECMO, while outcomes are poor in adults with septic shock without severe left ventricular depression. Therefore, VA ECMO may be a viable treatment option in carefully selected adult patients with refractory septic shock.
Article
Cardiac & Cardiovascular Systems
Carlos D. Davila, Michele Esposito, Colin S. Hirst, Kevin Morine, Lena Jorde, Sarah Newman, Vikram Paruchuri, Evan Whitehead, Katherine L. Thayer, Navin K. Kapur
Summary: This study examined longitudinal hemodynamic changes in patients with cardiogenic shock receiving AMCS and found that improvement in right atrial pressure was associated with better survival. Baseline right atrial pressure, along with right atrial pressure at 24 hours post device implant and final right atrial pressure, were significant predictors of in-hospital mortality, highlighting the importance of venous congestion as a prognostic marker for mortality in this patient population.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Benedikt Schrage, Jonas Sundermeyer, Benedikt Norbert Beer, Letizia Bertoldi, Alexander Bernhardt, Stefan Blankenberg, Jeroen Dauw, Zouhir Dindane, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Peter Luedike, Enzo Luesebrink, Norman Mangner, Octavian Maniuc, Sven Moebius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, Paul Christian Schulze, Robert H. G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Antonia Wechsler, Ralf Westenfeld, Ephraim Winzer, Dirk Westermann
Summary: This study aimed to evaluate the use of mechanical circulatory support (MCS) for the treatment of non-ischaemic cardiogenic shock (CS). The results showed that the use of MCS was associated with a lower 30-day mortality rate in patients with non-ischaemic CS. However, MCS treatment was also associated with more complications.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Engineering, Biomedical
Gretel Monreal, Steven C. Koenig, Mustafa Ertan Taskin, Charles Shambaugh, Jeffrey A. LaRose, Mark S. Slaughter
Summary: RT Cardiac Systems is developing an intravascular percutaneous mechanical circulatory support (pMCS) device drive system for high-risk percutaneous coronary intervention and emergent cardiogenic shock. The prototype pMCS system has been successfully tested and demonstrated feasibility in terms of engineering design and performance.
Review
Cardiac & Cardiovascular Systems
Sandeep Dayanand, Jasmin M. Martinez, Vincent M. Figueredo, Shuchita Gupta
Summary: Women with acute cardiogenic shock and chronic end-stage heart failure may benefit as much as, or even more than, men from mechanical circulatory support (MCS) devices, despite being usually in a more critical condition upon admission. However, women have been under-represented in clinical trials of MCS devices, and limited evidence suggests they may benefit more from temporary MCS in cases of acute myocardial infarction.
JOURNAL OF CARDIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Danilo Obradovic, Anne Freund, Hans-Josef Feistritzer, Dmitry Sulimov, Goran Loncar, Mohamed Abdel-Wahab, Uwe Zeymer, Steffen Desch, Holger Thiele
Summary: CS is a major concern in acute cardiovascular medicine, with high mortality despite advancements in treatment. Temporary MCS devices may improve clinical outcomes in selected CS patients, but large-scale randomized controlled trials are needed to confirm mortality reduction and further research is necessary to understand the clinical value of MCS in CS.
PROGRESS IN CARDIOVASCULAR DISEASES
(2021)
Article
Medicine, General & Internal
Styliani Syntila, Georgios Chatzis, Birgit Markus, Holger Ahrens, Christian Waechter, Ulrich Luesebrink, Dimitar Divchev, Harald Schuett, Panagiota-Eleni Tsalouchidou, Andreas Jerrentrup, Mariana Parahuleva, Bernhard Schieffer, Konstantinos Karatolios
Summary: This study compared the outcomes of Impella and extracorporeal life support (ECLS) in patients with post-cardiac arrest cardiogenic shock complicating acute myocardial infarction. Impella and ECLS patients had comparable hospital and 12-month survival rates, but Impella patients showed greater left ventricle ejection-fraction improvement and fewer device-related complications. Subgroup analyses indicated that Impella was associated with better survival in patients with lower-risk features.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biology
Gaik Nersesian, Sascha Ott, Alexander Fardman, Pia Lanmueller, Daniel Lewin, Alexander Bernhardt, Fabian Emrich, Gloria Faerber, Gabor Szabo, Mehmet Oezkur, Bernd Panholzer, Sebastian V. Rojas, Diyar Saeed, Bastian Schmack, Gregor Warnecke, Daniel Zimpfer, Herko Grubitzsch, Volkmar Falk, Evgenij Potapov
Summary: Mechanical circulatory support is effective in managing postcardiotomy cardiogenic shock by stabilizing patients' hemodynamics and ensuring adequate organ perfusion. The combination of extracorporeal life support and a microaxial flow pump has emerged as a valuable tool in surgical procedures. This publication provides recommendations for the application and weaning of temporary mechanical circulatory support in cardiogenic shock patients, based on consensus among leading cardiac centers in German-speaking countries.
Article
Cardiac & Cardiovascular Systems
Francesco Santoro, Adriana Mallardi, Alessandra Leopizzi, Enrica Vitale, Thomas Stiermaier, Paolo Trambaiolo, Matteo Di Biase, Ingo Eitel, Natale Daniele Brunetti
Summary: Takotsubo syndrome is a transient left ventricle dysfunction triggered by emotional or physical stress, without significant coronary artery disease. Cardiac imaging tools play a crucial role in diagnosis and management, including coronary angiography for excluding pathological stenosis, and transthoracic echocardiography for early evaluation of left ventricle function.
HEART FAILURE REVIEWS
(2022)
Article
Cardiac & Cardiovascular Systems
Luca Baldetti, Guglielmo Gallone, Stefania Sacchi, Vittorio Pazzanese, Mario Gramegna, Francesco Calvo, Antonio Boccellino, Silvia Ajello, Anna Mara Scandroglio, Alberto Maria Cappelletti
Summary: This case emphasizes the significant role of an intra-aortic balloon pump (IABP) in reducing afterload in acute heart failure with reduced ejection fraction (AHFrEF). AHFrEF patients have high sensitivity to afterload, and removing the IABP can lead to pulmonary edema and cardiogenic shock even after proper decongestion. Initiating angiotensin receptor-neprilysin inhibitor therapy during IABP support can serve as a bridge for weaning such afterload-sensitive patients off the IABP.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
A. Aljehani, T. Kew, S. Baig, H. Cox, L. C. Sommerfeld, B. Ensam, M. Kalla, R. P. Steeds, L. Fabritz
Summary: This study describes the initial presentation and cardiac phenotype of definite and non-definite ARVC patients. It found that patients in the definite ARVC group had more pronounced symptoms, more abnormal electrocardiographic and cardiac imaging features, and a higher incidence of major adverse cardiac events.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Cardiac & Cardiovascular Systems
Driss Laghlam, Olivier Touboul, Morgane Herry, Philippe Estagnasie, Jean-Claude Dib, Mohamed Baccouche, Alain Brusset, Lee S. Nguyen, Pierre Squara
Summary: This study provides a comprehensive overview of patients who developed Takotsubo cardiomyopathy after cardiac surgery. The results show that this complication is rare but serious, occurring mainly after mitral and/or tricuspid valve repair procedures, and is associated with a high rate of cardiogenic shock.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
David A. Baran, Abhishek Jaiswal, Felix Hennig, Evgenij Potapov
Summary: Clinicians and regulators are struggling to develop allocation systems that balance waitlist mortality and donor availability in the face of a chronic donor shortage. This article discusses the characteristics and limitations of current devices used for temporary mechanical circulatory support (tMCS) as a bridging strategy, as well as the evolving outcomes of transplantation following device support. It also reviews and compares heart transplantation allocation schemas in different countries. The article proposes key principles to guide changes in the next generation of donor allocation systems, including calculated scores, time limits on high urgency statuses, emphasis on durable mechanical support therapies, and peer review of exceptions to organ allocation policy.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2022)
