Saturated Fatty Acid Increases Lung Macrophages and Augments House Dust Mite-Induced Airway Inflammation in Mice Fed with High-Fat Diet

Obesity and Asthma: Microbiome–Metabolome Interactions

(2016) Stephanie A. Shore et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

Metabolic consequences of obesity as an “outside in” mechanism of disease severity in asthma

(2016) Michael C. Peters et al.   EUROPEAN RESPIRATORY JOURNAL

Lipopolysaccharides promote a shift from Th2-derived airway eosinophilic inflammation to Th17-derived neutrophilic inflammation in an ovalbumin-sensitized murine asthma model

(2016) Shengtao Zhao et al.   JOURNAL OF ASTHMA

Current concepts of severe asthma

(2016) Anuradha Ray et al.   JOURNAL OF CLINICAL INVESTIGATION

The relation of saturated fatty acids with low-grade inflammation and cardiovascular disease

(2016) Begoña Ruiz-Núñez et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Targeting inflammation in metabolic syndrome

(2016) Francine K. Welty et al.   Translational Research

The Macrophage Switch in Obesity Development

(2016) Angela Castoldi et al.   Frontiers in Immunology

Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model

(2016) Hiroki Tashiro et al.   PLoS One

Innate and ozone-induced airway hyperresponsiveness in obese mice: role of TNF-α

(2015) Alison Suzanne Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity

(2015) Orla M. Finucane et al.   DIABETES

The “Big Bang” in obese fat: Events initiating obesity-induced adipose tissue inflammation

(2015) Felix M. Wensveen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Obesity shifts house dust mite-induced airway cellular infiltration from eosinophils to macrophages: effects of glucocorticoid treatment

(2015) J. Diaz et al.   IMMUNOLOGIC RESEARCH

Palmitate differentially regulates the polarization of differentiating and differentiated macrophages

(2015) Fangming Xiu et al.   IMMUNOLOGY

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice

(2015) Lei Zhao et al.   Scientific Reports

β2 adrenergic agonist attenuates house dust mite-induced allergic airway inflammation through dendritic cells

(2014) Go Kato et al.   BMC IMMUNOLOGY

Macrophage activation, age and sex effects of immunometabolism in obese asthma

(2014) Hashim A. Periyalil et al.   EUROPEAN RESPIRATORY JOURNAL

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice

(2014) Morgan L. Moon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Identification of Myeloid Cell Subsets in Murine Lungs Using Flow Cytometry

(2013) Rinat Zaynagetdinov et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The role of macrophages in obstructive airways disease: Chronic obstructive pulmonary disease and asthma

(2013) Konstantinos Pappas et al.   CYTOKINE

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

(2013) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Increased Saturated Fatty Acids in Obesity Alter Resolution of Inflammation in Part by Stimulating Prostaglandin Production

(2013) J. Hellmann et al.   JOURNAL OF IMMUNOLOGY

Interleukin-17–producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

(2013) Hye Young Kim et al.   NATURE MEDICINE

Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist

(2013) Brian R Leaker et al.   RESPIRATORY RESEARCH

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

(2012) Kosei Eguchi et al.   Cell Metabolism

Severe asthma: from characteristics to phenotypes to endotypes

(2012) S. Wenzel   CLINICAL AND EXPERIMENTAL ALLERGY

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

(2012) Jun Panee   CYTOKINE

The Cost of Persistent Asthma in Europe: An International Population-Based Study in Adults

(2012) Simone Accordini et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Obese Mexican American Children Have Elevated MCP-1, TNF- , Monocyte Concentration, and Dyslipidemia

(2012) W. L. Breslin et al.   PEDIATRICS

Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation

(2011) Anne E. Dixon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Costs of asthma in the United States: 2002-2007

(2011) Sarah Beth L. Barnett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Molecular Mechanisms by Which Saturated Fatty Acids Modulate TNF-α Expression in Mouse Macrophage Lineage

(2010) Thais Martins Lima-Salgado et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

International Trends in Asthma Mortality Rates in the 5- to 34-Year Age Group

(2009) Meme Wijesinghe et al.   CHEST

Body Mass and Glucocorticoid Response in Asthma

(2008) E. Rand Sutherland et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The relationship between obesity and asthma severity and control in adults

(2008) David M. Mosen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY