Genetic and Syndromic Causes of Obesity and its Management

Early-Onset Obesity: Unrecognized First Evidence for GNAS Mutations and Methylation Changes

(2017) Annette Grüters-Kieslich et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Response to Letter: “Pediatric Obesity—Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline”

(2017) Dennis M. Styne et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Whole exome sequencing identifies a homozygous nonsense variation in ALMS1 gene in a patient with syndromic obesity

(2017) Aneek Das Bhowmik et al.   Obesity Research & Clinical Practice

Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism

(2017) Dennis Löffler et al.   Molecular Metabolism

Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity

(2016) Peter Kühnen et al.   Cell Metabolism

Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity

(2016) Omar Ali et al.   Epigenetics

Prevalence and phenotypic characterization of MC4R variants in a large pediatric cohort

(2016) H Vollbach et al.   INTERNATIONAL JOURNAL OF OBESITY

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

(2016) Peter Kühnen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Absence of mutations in HCRT , HCRTR1 and HCRTR2 in patients with ROHHAD

(2016) Sarah F. Barclay et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A large multiexonic genomic deletion within theALMS1gene causes Alström syndrome in a consanguineous Pakistani family

(2015) K. Nikopoulos et al.   CLINICAL GENETICS

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene

(2015) Martin Wabitsch et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Biologically Inactive Leptin and Early-Onset Extreme Obesity

(2015) Martin Wabitsch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): exome sequencing of trios, monozygotic twins and tumours

(2015) Sarah F. Barclay et al.   Orphanet Journal of Rare Diseases

Screening for Hormonal, Monogenic, and Syndromic Disorders in Obese Infants and Children

(2014) Kelly Mason et al.   PEDIATRIC ANNALS

A Case of Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, Autonomic Dysregulation, and Neural Crest Tumor: Rohhadnet Syndrome

(2012) Ayhan Abaci et al.   Endocrine Practice

Bardet–Biedl syndrome

(2012) Elizabeth Forsythe et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Metformin in Obese Children and Adolescents: The MOCA Trial

(2012) D. Kendall et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Anesthetic considerations for rapid-onset obesity, hypoventilation, hypothalamic dysfunction, and autonomic dysfunction (ROHHAD) syndrome in children

(2012) Arvind Chandrakantan et al.   PEDIATRIC ANESTHESIA

An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity

(2012) Peter Kuehnen et al.   PLoS Genetics

Effects of Metformin on Body Weight and Body Composition in Obese Insulin-Resistant Children: A Randomized Clinical Trial

(2011) J. A. Yanovski et al.   DIABETES

Hypothalamic proopiomelanocortin processing and the regulation of energy balance

(2011) Sharon L. Wardlaw   EUROPEAN JOURNAL OF PHARMACOLOGY

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

(2009) Seongjin Seo et al.   HUMAN MOLECULAR GENETICS