Article
Computer Science, Artificial Intelligence
Lei Yu, Xiang Zhang, Wei Liao, Wen Yang, Gui-Song Xia
Summary: This paper presents an Event-based SAI (E-SAI) method using an event camera, which achieves the seeing-through effect by blurring out off-focus foreground occlusions and recovering in-focus occluded scenes from multi-view images. It addresses the performance deterioration problem caused by dense occlusions and extreme lighting conditions.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
(2023)
Article
Computer Science, Artificial Intelligence
Yu-Lun Liu, Wei-Sheng Lai, Ming-Hsuan Yang, Yung-Yu Chuang, Jia-Bin Huang
Summary: This article presents a learning-based approach to remove unwanted obstructions from images captured by a moving camera. The method leverages motion differences to recover layers and utilizes a deep convolutional neural network for layer reconstruction. Experimental results demonstrate the effectiveness of the proposed method.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
(2022)
Article
Chemistry, Multidisciplinary
Di Wang, Yuhao Li, Guanqing Zhou, Emely Gu, Ruoxi Xia, Buyi Yan, Jizhong Yao, Haiming Zhu, Xinhui Lu, Hin-Lap Yip, Hongzheng Chen, Chang-Zhi Li
Summary: Transparent power windows are developed using a new design of semitransparent organic solar cells, which efficiently utilize solar photons from visible to infrared range for energy generation and saving. These power windows have high color fidelity, outstanding power conversion efficiency, and reject infrared photons. Large-area modules with record-breaking performance have been demonstrated and can contribute to carbon neutrality worldwide.
ENERGY & ENVIRONMENTAL SCIENCE
(2022)
Article
Biochemical Research Methods
Guoyong Yan, Chun-ang Lian, Yi Lan, Pei-Yuan Qian, Lisheng He
Summary: The study analyzed the eye proteome of the dominant hadal endemic snailfish Pseudoliparis swirei from the Mariana Trench, revealing abundant metabolic activities in the eye and its functionality as a visual organ. Additionally, proteins related to extreme environment adaptation were highly expressed in the eye, providing insights into the molecular mechanisms underlying the vision of hadal snailfish.
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Multidisciplinary Sciences
Lujing Chen, Guang Li, Zheng Jiang, King-Wai Yau
Summary: Nonimage-forming vision in mammals is mediated primarily by melanopsin-expressing ipRGCs. The study reveals that in M1-ipRGCs, melanopsin activates phospholipase C-β4 to open TRPC6 and TRPC7 channels, while in M2 and M4-ipRGCs, cyclic nucleotide-mediated phototransduction activates hyperpolarization and cyclic nucleotide-gated channels. Additionally, it is found that the upstream G protein is Gq, which directly activates adenylyl cyclase (AC) for signaling.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Green & Sustainable Science & Technology
Martijn Gerritsen, Henk-Jan Kooij, Martijn Groenleer, Erwin van der Krabben
Summary: This paper explores the evolutionary nature of experimentalist governance and illustrates the diverse evolutionary pathways that experimentalism can take through a case study of energy transition governance in the Netherlands. The paper proposes evolutionary path- and context-mapping as a useful tool for identifying and understanding the multiple pathways of experimentalism.
Article
Chemistry, Medicinal
Marco Bassetto, Jordan Zaluski, Bowen Li, Jianye Zhang, Mohsen Badiee, Philip D. Kiser, Gregory P. Tochtrop
Summary: The visual cycle is essential for vision, and RPE65 plays a crucial role in the isomerization of retinal molecules. Emixustat, a retinoid-mimetic RPE65 inhibitor, has been developed for the treatment of retinopathies. However, its further development is limited by pharmacokinetic issues. By synthesizing novel derivatives and testing their inhibitory activity, we identified a potent secondary amine derivative with resistance to deamination and preserved RPE65 inhibitory activity. This study provides insights into modifying the emixustat molecule to optimize its pharmacological properties.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Computer Science, Information Systems
Monica Lestari Paramita, Kalia Orphanou, Evgenia Christoforou, Jahna Otterbacher, Frank Hopfgartner
Summary: When using Google image search for Covid-19 information, users may see different content based on variations in information needs, geo-locations, and query languages.
INFORMATION PROCESSING & MANAGEMENT
(2021)
Review
Neurosciences
Fatima Abbas, Frans Vinberg
Summary: Animals use visual and olfactory stimuli to guide survival behaviors, with specific signal transduction mechanisms in primary sensory neurons. The olfactory and phototransduction pathways in vertebrates and invertebrates show similarities but also distinct differences in signal transduction and response mechanisms, reflecting their unique adaptations for survival.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2021)
Article
Computer Science, Artificial Intelligence
Samyakh Tukra, Hani J. Marcus, Stamatia Giannarou
Summary: One of the challenges of minimally invasive surgery (MIS) is the limited visual field, and this paper proposes an unsupervised deep learning framework to reconstruct the surgical scene view under occlusions, providing better intraoperative vision for surgeons.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
(2022)
Article
Environmental Studies
Nir Cohen, Tatiana Fogelman, Henrik Lebuhn
Summary: This article discusses the importance of migration industries in understanding urban issues, emphasizing the three key analytical perspectives that the focus on migration industries can provide, and discussing the connection between urbanization of migration studies and migration industries.
Article
Neurosciences
Juan M. Angueyra, Jacob Baudin, Gregory W. Schwartz, Fred Rieke
Summary: This study explores how macaque cone photoreceptors maintain sensitivity under fast saccadic eye movements. The research shows that adaptation causes nonlinearity in cone responses to naturalistic stimuli, depending on stimulus history. A biophysical model can accurately predict cone responses to various stimuli.
JOURNAL OF NEUROSCIENCE
(2022)
News Item
Physics, Multidisciplinary
Lilian Childress, Jack Sankey
Summary: Integrating quantum technology with existing telecom infrastructure is challenging due to a mismatch in operating frequencies. However, an optomechanical resonator now provides a strain-mediated spin-photon interface for long-distance quantum networks.
Article
Entomology
Minjing Su, Feimin Yuan, Tiantian Li, Cong Wei
Summary: Cicadas undergo significant changes in the color and structure of their compound eyes during development. This study used transcriptome analyses to determine the timing and molecular mechanisms underlying this transformation in the cicada Meimuna mongolica. The results shed light on the developmental and adaptive changes in compound eyes in insects and provide insight into their visual abilities in different habitats.
Article
Chemistry, Physical
Malkeshkumar Patel, Vinayak Vitthal Satale, Sangho Kim, Kibum Lee, Joondong Kim
Summary: Solar energy is an abundant and clean energy source that can support current and future energy demands. However, its intermittent nature limits its practical use. To address this issue, researchers have proposed an integrated system combining transparent photovoltaics and transparent photoelectrochemical cells, which can generate clean and continuous energy with high efficiency and good transparency.
JOURNAL OF POWER SOURCES
(2022)
Review
Biotechnology & Applied Microbiology
Jeffrey S. Smith, Robert J. Lefkowitz, Sudarshan Rajagopal
NATURE REVIEWS DRUG DISCOVERY
(2018)
Review
Pharmacology & Pharmacy
Chen Wang, Pan Xu, Luyu Zhang, Jing Huang, Kongkai Zhu, Cheng Luo
FRONTIERS IN PHARMACOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Tian Wang, Juergen Reingruber, Michael L. Woodruff, Anurima Majumderil, Andres Camarena, Nikolai O. Artemyev, Gordon L. Fain, Jeannie Chen
JOURNAL OF BIOLOGICAL CHEMISTRY
(2018)
Article
Multidisciplinary Sciences
Yanyong Kang, Oleg Kuybeda, Parker W. de Waal, Somnath Mukherjee, Ned Van Eps, Przemyslaw Dutka, X. Edward Zhou, Alberto Bartesaghi, Satchal Erramilli, Takefumi Morizumi, Xin Gu, Yanting Yin, Ping Liu, Yi Jiang, Xing Meng, Gongpu Zhao, Karsten Melcher, Oliver P. Ernst, Anthony A. Kossiakoff, Sriram Subramaniam, H. Eric Xu
Article
Medicine, Research & Experimental
Ala Moshiri, Rui Chen, Soohyun Kim, R. Alan Harris, Yumei Li, Muthuswamy Raveendran, Sarah Davis, Qingnan Liang, Ori Pomerantz, Jun Wang, Laura Garzel, Ashley Cameron, Glenn Yiu, J. Timothy Stout, Yijun Huang, Christopher J. Murphy, Jeffrey Roberts, Kota N. Gopalakrishna, Kimberly Boyd, Nikolai O. Artemyev, Jeffrey Rogers, Sara M. Thomasy
JOURNAL OF CLINICAL INVESTIGATION
(2019)
Article
Biochemical Research Methods
Sebastiaan C. de Graaf, Oleg Klykov, Henk van den Toorn, Richard A. Scheltema
JOURNAL OF PROTEOME RESEARCH
(2019)
Article
Biochemistry & Molecular Biology
Mohammadjavad Mohammadi, Hossein Mohammadiarani, Vincent S. Shaw, Richard R. Neubig, Harish Vashisth
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
(2019)
Article
Multidisciplinary Sciences
Kevin D. Schuster, Mohammadjavad Mohammadi, Karyn B. Cahill, Suzanne L. Matte, Alexis D. Maillet, Harish Vashisth, Rick H. Cote
Article
Multidisciplinary Sciences
Sahil Gulati, Krzysztof Palczewski, Andreas Engel, Henning Stahlberg, Lubomir Kovacik
Article
Biochemistry & Molecular Biology
Xin Wang, David C. Plachetzki, Rick H. Cote
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Feixia Chu, Donna Hogan, Richa Gupta, Xiong-Zhuo Gao, Hieu T. Nguyen, Rick H. Cote
JOURNAL OF MOLECULAR BIOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Michael J. Irwin, Richa Gupta, Xiong-Zhuo Gao, Karyn B. Cahill, Feixia Chu, Rick H. Cote
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Richa Gupta, Yong Liu, Huanchen Wang, Christopher T. Nordyke, Ryan Z. Puterbaugh, Wenjun Cui, Krisztina Varga, Feixia Chu, Hengming Ke, Harish Vashisth, Rick H. Cote
JOURNAL OF MOLECULAR BIOLOGY
(2020)
Review
Physiology
Rick H. Cote
Summary: This review article discusses the role of cGMP in the visual signaling pathway of the vertebrate retina, particularly focusing on the metabolism of cGMP in rod and cone photoreceptors. It highlights recent advances in understanding the structural and conformational changes involved in the activation of PDE6 by transducin and the regulation of its lifetime, as well as the potential therapeutic applications of pharmacological compounds targeting PDE6 in inherited retinal diseases.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
(2021)
Article
Biology
Michael Irwin, Xin Wang, Rick Cote
Summary: This study describes the use of silica nanoparticles coated with a phospholipid bilayer to reconstitute and study the GPCR signaling pathway. The use of these lipobeads allows for efficient activation of the pathway and detection of protein-protein interactions. The method has advantages over traditional liposome preparations and is applicable to other membrane-confined signaling pathways.