A bacteriophages journey through the human body

Viruses comprise an extensive pool of mobile genetic elements in eukaryote cell cultures and human clinical samples

(2017) Jakob Thannesberger et al.   FASEB JOURNAL

Filamentous Bacteriophage as a Novel Therapeutic Tool for Alzheimer's Disease Treatment

(2017) Beka Solomon   JOURNAL OF ALZHEIMERS DISEASE

Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos

(2016) Mahdi Karimi et al.   ADVANCED DRUG DELIVERY REVIEWS

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

Temporal Stability of the Human Skin Microbiome

(2016) Julia Oh et al.   CELL

Human Microbiota-Associated Mice: A Model with Challenges

(2016) Marie-Claire Arrieta et al.   Cell Host & Microbe

Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier

(2016) David S. Hersh et al.   CURRENT PHARMACEUTICAL DESIGN

Spatial disturbances in altered mucosal and luminal gut viromes of diet-induced obese mice

(2016) Min-Soo Kim et al.   ENVIRONMENTAL MICROBIOLOGY

Phage M13 for the treatment of Alzheimer and Parkinson disease

(2016) Joachim Messing   GENE

Viruses and the origin of microbiome selection and immunity

(2016) Steven D Quistad et al.   ISME Journal

Lytic to temperate switching of viral communities

(2016) B. Knowles et al.   NATURE

Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood

(2016) Laura F. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Healthy human gut phageome

(2016) Pilar Manrique et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Significance of Mutualistic Phages for Bacterial Ecology and Evolution

(2016) Nancy Obeng et al.   TRENDS IN MICROBIOLOGY

Eukaryotic association module in phage WO genomes from Wolbachia

(2016) Sarah R. Bordenstein et al.   Nature Communications

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

(2016) Shafiqul Alam Sarker et al.   EBioMedicine

Piggyback-the-Winner in host-associated microbial communities

(2016) Cynthia B Silveira et al.   npj Biofilms and Microbiomes

To kill or not to kill: The balance between lytic and lysogenic viral infection is driven by trophic status

(2016) Jérôme P. Payet et al.   LIMNOLOGY AND OCEANOGRAPHY

Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid

(2016) Maria Carmen Collado et al.   Scientific Reports

Coral Mucus Is a Hot Spot for Viral Infections

(2015) Hanh Nguyen-Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease

(2015) Jason M. Norman et al.   CELL

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

Phage-bacteria interaction network in human oral microbiome

(2015) Jinfeng Wang et al.   ENVIRONMENTAL MICROBIOLOGY

Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

(2015) Marie Boegh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

Early life dynamics of the human gut virome and bacterial microbiome in infants

(2015) Efrem S Lim et al.   NATURE MEDICINE

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Subdiffusive motion of bacteriophage in mucosal surfaces increases the frequency of bacterial encounters

(2015) Jeremy J. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut DNA viromes of Malawian twins discordant for severe acute malnutrition

(2015) Alejandro Reyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophage-Derived Vectors for Targeted Cancer Gene Therapy

(2015) Md Pranjol et al.   Viruses-Basel

Oral Application of T4 Phage Induces Weak Antibody Production in the Gut and in the Blood

(2015) Joanna Majewska et al.   Viruses-Basel

Mammalian Host-Versus-Phage immune response determines phage fate in vivo

(2015) Katarzyna Hodyra-Stefaniak et al.   Scientific Reports

The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease

(2015) Robert P. Dickson et al.   PLoS Pathogens

The human urine virome in association with urinary tract infections

(2015) Tasha M. Santiago-Rodriguez et al.   Frontiers in Microbiology

The human gut virome: a multifaceted majority

(2015) Lesley A. Ogilvie et al.   Frontiers in Microbiology

Microbiota of Human Breast Tissue

(2014) Camilla Urbaniak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Species-specific ant brain manipulation by a specialized fungal parasite

(2014) Charissa de Bekker et al.   BMC EVOLUTIONARY BIOLOGY

Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

(2014) Tu Anh N. Pham et al.   Cell Host & Microbe

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

(2014) Thaher Pelaseyed et al.   IMMUNOLOGICAL REVIEWS

Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens

(2014) J. C. H. Tam et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bacteriophages and medical oncology: targeted gene therapy of cancer

(2014) Babak Bakhshinejad et al.   MEDICAL ONCOLOGY

A Biophysical Basis for Mucus Solids Concentration as a Candidate Biomarker for Airways Disease

(2014) David B. Hill et al.   PLoS One

Viral Communities Associated with Human Pericardial Fluids in Idiopathic Pericarditis

(2014) Laura Fancello et al.   PLoS One

Elevated Levels of Circulating DNA in Cardiovascular Disease Patients: Metagenomic Profiling of Microbiome in the Circulation

(2014) Vasudevan Dinakaran et al.   PLoS One

Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems

(2014) A. Ardeshir et al.   Science Translational Medicine

High occurrence of viruses in the mucus layer of scleractinian corals

(2014) Hanh Nguyen-Kim et al.   Environmental Microbiology Reports

A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes

(2014) Bas E. Dutilh et al.   Nature Communications

Probing the Endocytic Pathways of the Filamentous Bacteriophage in Live Cells Using Ratiometric pH Fluorescent Indicator

(2014) Ye Tian et al.   Advanced Healthcare Materials

Bacteriophages: an underestimated role in human and animal health?

(2014) Marianne De Paepe et al.   Frontiers in Cellular and Infection Microbiology

Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?

(2014) Roman M. Stilling et al.   Frontiers in Cellular and Infection Microbiology

Human milk metagenome: a functional capacity analysis

(2013) Tonya L Ward et al.   BMC MICROBIOLOGY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Translating translational research: mouse models of human disease

(2013) Amanda M Burkhardt et al.   Cellular & Molecular Immunology

Bacteriophage–host interaction: from splendid isolation into a messy reality

(2013) Harald Brüssow   CURRENT OPINION IN MICROBIOLOGY

The cell biology of the intestinal epithelium and its relation to inflammatory bowel disease

(2013) J. Jasper Deuring et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Etiology of Diarrhea in Bangladeshi Infants in the First Year of Life Analyzed Using Molecular Methods

(2013) M. Taniuchi et al.   JOURNAL OF INFECTIOUS DISEASES

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome

(2013) Sheetal R. Modi et al.   NATURE

Resident viruses and their interactions with the immune system

(2013) Breck A Duerkop et al.   NATURE IMMUNOLOGY

Microfabrication of human organs-on-chips

(2013) Dongeun Huh et al.   Nature Protocols

In vitro and in vivo delivery of genes and proteins using the bacteriophage T4 DNA packaging machine

(2013) P. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of Levy walk foraging patterns in human hunter-gatherers

(2013) D. A. Raichlen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid evolution of the human gut virome

(2013) S. Minot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gnotobiotic mouse model of phage-bacterial host dynamics in the human gut

(2013) A. Reyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophage adhering to mucus provide a non-host-derived immunity

(2013) J. J. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens

(2013) F. Randow et al.   SCIENCE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

The New Era of the Lymphatic System: No Longer Secondary to the Blood Vascular System

(2013) I. Choi et al.   Cold Spring Harbor Perspectives in Medicine

Mom Knows Best: The Universality of Maternal Microbial Transmission

(2013) Lisa J. Funkhouser et al.   PLOS BIOLOGY

Pathogenic Simian Immunodeficiency Virus Infection Is Associated with Expansion of the Enteric Virome

(2012) Scott A. Handley et al.   CELL

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Human milk oligosaccharides: Every baby needs a sugar mama

(2012) L. Bode   GLYCOBIOLOGY

Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2

(2012) Kristina A Thomsson et al.   GLYCOBIOLOGY

Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities

(2012) Yan Wei Lim et al.   Journal of Cystic Fibrosis

Convection-enhanced delivery of M13 bacteriophage to the brain

(2012) Alexander Ksendzovsky et al.   JOURNAL OF NEUROSURGERY

Food in an evolutionary context: insights from mother's milk

(2012) Katie Hinde et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

The human microbiome: ecosystem resilience and health

(2012) David A Relman   NUTRITION REVIEWS

The human milk microbiota: Origin and potential roles in health and disease

(2012) Leónides Fernández et al.   PHARMACOLOGICAL RESEARCH

Human Skin Microbiota: High Diversity of DNA Viruses Identified on the Human Skin by High Throughput Sequencing

(2012) Vincent Foulongne et al.   PLoS One

Foraging success of biological Levy flights recorded in situ

(2012) N. E. Humphries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypervariable loci in the human gut virome

(2012) S. Minot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A composite bacteriophage alters colonization by an intestinal commensal bacterium

(2012) B. A. Duerkop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Application of Ecological Theory Toward an Understanding of the Human Microbiome

(2012) E. K. Costello et al.   SCIENCE

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

What is needed for phage therapy to become a reality in Western medicine?

(2012) Harald Brüssow   VIROLOGY

Oral T4-like phage cocktail application to healthy adult volunteers from Bangladesh

(2012) Shafiqul Alam Sarker et al.   VIROLOGY

The Early Settlers: Intestinal Microbiology in Early Life

(2012) Petra A.M.J. Scholtens et al.   Annual Review of Food Science and Technology

Human milk: a source of more life than we imagine

(2012) P.V. Jeurink et al.   Beneficial Microbes

The Evolution of Mutualism in Gut Microbiota Via Host Epithelial Selection

(2012) Jonas Schluter et al.   PLOS BIOLOGY

Diversity and Abundance of Single-Stranded DNA Viruses in Human Feces

(2011) Min-Soo Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The human gut virome: Inter-individual variation and dynamic response to diet

(2011) S. Minot et al.   GENOME RESEARCH

Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein

(2011) I. V. Alymova et al.   GLYCOBIOLOGY

The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis

(2011) Y. H. Sheng et al.   GUT

Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome

(2011) David T Pride et al.   ISME Journal

CFTR anion channel modulates expression of human transmembrane mucin MUC3 through the PDZ protein GOPC

(2011) T. Pelaseyed et al.   JOURNAL OF CELL SCIENCE

Structure of the Three N-Terminal Immunoglobulin Domains of the Highly Immunogenic Outer Capsid Protein from a T4-Like Bacteriophage

(2011) A. Fokine et al.   JOURNAL OF VIROLOGY

Discovery of Cyanophage Genomes Which Contain Mitochondrial DNA Polymerase

(2011) Yi-Wah Chan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

The good viruses: viral mutualistic symbioses

(2011) Marilyn J. Roossinck   NATURE REVIEWS MICROBIOLOGY

Bacterial Meningitis in the United States, 1998–2007

(2011) Michael C. Thigpen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oligosaccharide Binding Proteins from Bifidobacterium longum subsp. infantis Reveal a Preference for Host Glycans

(2011) Daniel Garrido et al.   PLoS One

Predator Cat Odors Activate Sexual Arousal Pathways in Brains of Toxoplasma gondii Infected Rats

(2011) Patrick K. House et al.   PLoS One

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis

(2010) Arthur Kaser et al.   CURRENT OPINION IN GASTROENTEROLOGY

Membrane-tethered mucins have multiple functions on the ocular surface

(2010) Bharathi Govindarajan et al.   EXPERIMENTAL EYE RESEARCH

Mining metagenomic data for novel domains: BACON, a new carbohydrate-binding module

(2010) Luciane V. Mello et al.   FEBS LETTERS

Viral and microbial community dynamics in four aquatic environments

(2010) Beltran Rodriguez-Brito et al.   ISME Journal

Interaction between the extracellular matrix and lymphatics: Consequences for lymphangiogenesis and lymphatic function

(2010) Helge Wiig et al.   MATRIX BIOLOGY

Functional analysis of the highly antigenic outer capsid protein, Hoc, a virus decoration protein from T4-like bacteriophages

(2010) Taheri Sathaliyawala et al.   MOLECULAR MICROBIOLOGY

Viruses in the faecal microbiota of monozygotic twins and their mothers

(2010) Alejandro Reyes et al.   NATURE

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells

(2010) S Bafna et al.   ONCOGENE

Prebiotics and probiotics; modifying and mining the microbiota

(2010) Eamonn M.M. Quigley   PHARMACOLOGICAL RESEARCH

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

(2010) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Micro- and macrorheology of mucus

(2009) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

The putative role of the intestinal microbiota in the irritable bowel syndrome

(2009) S.M. Collins et al.   DIGESTIVE AND LIVER DISEASE

Inflammatory bowel disease, gut bacteria and probiotic therapy

(2009) Caroline Reiff et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease

(2009) Arthur Kaser et al.   SEMINARS IN IMMUNOLOGY

In vivo replication of T4 and T7 bacteriophages in germ-free mice colonized with Escherichia coli

(2009) Marietta Weiss et al.   VIROLOGY

Barrier properties of mucus

(2008) Richard A. Cone   ADVANCED DRUG DELIVERY REVIEWS

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Mucosal Glycan Foraging Enhances Fitness and Transmission of a Saccharolytic Human Gut Bacterial Symbiont

(2008) Eric C. Martens et al.   Cell Host & Microbe

Mucins in the mucosal barrier to infection

(2008) S K Linden et al.   Mucosal Immunology

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Microbial Prevalence, Diversity and Abundance in Amniotic Fluid During Preterm Labor: A Molecular and Culture-Based Investigation

(2008) Daniel B. DiGiulio et al.   PLoS One

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is meconium from healthy newborns actually sterile?

(2008) Esther Jiménez et al.   RESEARCH IN MICROBIOLOGY

Viral diversity and dynamics in an infant gut

(2008) Mya Breitbart et al.   RESEARCH IN MICROBIOLOGY

The role of microbiota in infectious disease

(2008) Bärbel Stecher et al.   TRENDS IN MICROBIOLOGY

Structure and Function of the Cell Surface (Tethered) Mucins

(2007) Christine L. Hattrup et al.   Annual Review of Physiology