The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation
出版年份 2017 全文链接
标题
The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation
作者
关键词
-
出版物
IMMUNOLOGICAL REVIEWS
Volume 277, Issue 1, Pages 113-127
出版商
Wiley
发表日期
2017-05-02
DOI
10.1111/imr.12550
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intracellular regulation of TNF activity in health and disease
- (2018) Eugene Varfolomeev et al. CYTOKINE
- The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis
- (2017) Yutaka Shimizu et al. HEPATOLOGY
- Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
- (2017) Philip A. Harris et al. JOURNAL OF MEDICINAL CHEMISTRY
- Necroptosis and Inflammation
- (2016) Kim Newton et al. Annual Review of Biochemistry
- DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death
- (2016) Roshan J. Thapa et al. Cell Host & Microbe
- Death receptor 3 mediates necroptotic cell death
- (2016) Sebastian Bittner et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Necrosome core machinery: MLKL
- (2016) Jing Zhang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency
- (2016) Christian Klemann et al. CLINICAL IMMUNOLOGY
- IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1
- (2016) Christiane Koppe et al. HEPATOLOGY
- NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
- (2016) Katerina Vlantis et al. IMMUNITY
- The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
- (2016) Silvia Alvarez-Diaz et al. IMMUNITY
- RIPK1 inhibits ZBP1-driven necroptosis during development
- (2016) Kim Newton et al. NATURE
- RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation
- (2016) Juan Lin et al. NATURE
- Programmed necrosis in inflammation: Toward identification of the effector molecules
- (2016) D. Wallach et al. SCIENCE
- Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling
- (2016) Nieves Peltzer et al. TRENDS IN CELL BIOLOGY
- More to Life than NF-κB in TNFR1 Signaling
- (2016) Adrian T. Ting et al. TRENDS IN IMMUNOLOGY
- Programmed Necrosis in the Cross Talk of Cell Death and Inflammation
- (2015) Francis Ka-Ming Chan et al. Annual Review of Immunology
- NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis
- (2015) Vangelis Kondylis et al. CANCER CELL
- Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis
- (2015) Lily Dara et al. HEPATOLOGY
- Cutting Edge: NF-κB p65 and c-Rel Control Epidermal Development and Immune Homeostasis in the Skin
- (2015) Yenkel Grinberg-Bleyer et al. JOURNAL OF IMMUNOLOGY
- NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
- (2015) Yves Dondelinger et al. MOLECULAR CELL
- Necroptosis and its role in inflammation
- (2015) Manolis Pasparakis et al. NATURE
- The diverse role of RIP kinases in necroptosis and inflammation
- (2015) John Silke et al. NATURE IMMUNOLOGY
- Diagnosis and Treatment in Anhidrotic Ectodermal Dysplasia with Immunodeficiency
- (2015) Tomoki Kawai et al. ALLERGOLOGY INTERNATIONAL
- Regulated Cell Death: Signaling and Mechanisms
- (2014) Avi Ashkenazi et al. Annual Review of Cell and Developmental Biology
- An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation
- (2014) Jiazhen Zhang et al. BIOCHEMICAL JOURNAL
- RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
- (2014) James A. Rickard et al. CELL
- RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
- (2014) Christopher P. Dillon et al. CELL
- Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout
- (2014) H Ehlken et al. CELL DEATH AND DIFFERENTIATION
- Epidermal p65/NF- B signalling is essential for skin carcinogenesis
- (2014) C. Kim et al. EMBO Molecular Medicine
- Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
- (2014) Tom Luedde et al. GASTROENTEROLOGY
- Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways
- (2014) Claudia Günther et al. GUT
- Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF- B Activation via the DNA-Dependent Activator of IFN Regulatory Factors
- (2014) W. J. Kaiser et al. JOURNAL OF IMMUNOLOGY
- Loss of Epithelial RelA Results in Deregulated Intestinal Proliferative/Apoptotic Homeostasis and Susceptibility to Inflammation
- (2014) K. A. Steinbrecher et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
- (2014) S. B. Berger et al. JOURNAL OF IMMUNOLOGY
- Epidermal RelA Specifically Restricts Contact Allergen–Induced Inflammation and Apoptosis in Skin
- (2014) Snehlata Kumari et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
- (2014) Nozomi Takahashi et al. NATURE
- RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
- (2014) Marius Dannappel et al. NATURE
- RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
- (2014) W. J. Kaiser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
- (2014) James A Rickard et al. eLife
- Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
- (2014) Snehlata Kumari et al. eLife
- Paneth Cells: Maestros of the Small Intestinal Crypts
- (2013) Hans C. Clevers et al. Annual Review of Physiology
- Control of Life-or-Death Decisions by RIP1 Kinase
- (2013) Dana E Christofferson et al. Annual Review of Physiology
- TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model
- (2013) F J Cubero et al. CELL DEATH AND DIFFERENTIATION
- Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice
- (2013) Snehlata Kumari et al. IMMUNITY
- Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis
- (2013) Ricardo Weinlich et al. Cell Reports
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
- (2012) Jason W. Upton et al. Cell Host & Microbe
- NEMO Inhibits Programmed Necrosis in an NFκB-Independent Manner by Restraining RIP1
- (2012) Marie Anne O’Donnell et al. PLoS One
- Loss of Caspase-8 Protects Mice Against Inflammation-Related Hepatocarcinogenesis but Induces Non-Apoptotic Liver Injury
- (2011) Christian Liedtke et al. GASTROENTEROLOGY
- The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation
- (2011) Marion C. Bonnet et al. IMMUNITY
- In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8
- (2011) Ian E. Gentle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Successful Treatment with Infliximab for Inflammatory Colitis in a Patient with X-linked Anhidrotic Ectodermal Dysplasia with Immunodeficiency
- (2011) Tomoyuki Mizukami et al. JOURNAL OF CLINICAL IMMUNOLOGY
- cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
- (2011) Maria Feoktistova et al. MOLECULAR CELL
- The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
- (2011) Tencho Tenev et al. MOLECULAR CELL
- FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
- (2011) Patrick-Simon Welz et al. NATURE
- Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
- (2011) Claudia Günther et al. NATURE
- Linear ubiquitination prevents inflammation and regulates immune signalling
- (2011) Björn Gerlach et al. NATURE
- Zalpha-domains: At the intersection between RNA editing and innate immunity
- (2011) Alekos Athanasiadis SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Inflammatory Bowel Disease
- (2010) Arthur Kaser et al. Annual Review of Immunology
- IL-10 family of cytokines
- (2010) Robert Sabat CYTOKINE & GROWTH FACTOR REVIEWS
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- NEMO/IKKγ regulates an early NF-κB-independent cell-death checkpoint during TNF signaling
- (2009) D Legarda-Addison et al. CELL DEATH AND DIFFERENTIATION
- DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB
- (2009) Manuele Rebsamen et al. EMBO REPORTS
- Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
- (2009) Andrew Kovalenko et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
- (2009) Tobias L. Haas et al. MOLECULAR CELL
- Dynamic expression of epidermal caspase 8 simulates a wound healing response
- (2009) Pedro Lee et al. NATURE
- Death receptor signal transducers: nodes of coordination in immune signaling networks
- (2009) Nicholas S Wilson et al. NATURE IMMUNOLOGY
- Epithelial apoptosis: Cause or consequence of ulcerative colitis?
- (2009) Jakob Benedict Seidelin et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
- (2009) D.-W. Zhang et al. SCIENCE
- TNF-α Induces Two Distinct Caspase-8 Activation Pathways
- (2008) Lai Wang et al. CELL
- Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity
- (2008) Eric P. Hanson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
- (2008) Maria A Ermolaeva et al. NATURE IMMUNOLOGY
- IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver
- (2008) T. Luedde et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started