Sortilin, Encoded by the Cardiovascular Risk Gene SORT1, and Its Suggested Functions in Cardiovascular Disease
出版年份 2015 全文链接
标题
Sortilin, Encoded by the Cardiovascular Risk Gene SORT1, and Its Suggested Functions in Cardiovascular Disease
作者
关键词
SORT1, Sortilin, PCSK9, IL6, TNF, LDL-cholesterol
出版物
Current Atherosclerosis Reports
Volume 17, Issue 4, Pages -
出版商
Springer Nature
发表日期
2015-02-21
DOI
10.1007/s11883-015-0496-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Sortilin deficiency improves the metabolic phenotype and reduces hepatic steatosis of mice subjected to diet-induced obesity
- (2015) Liane Rabinowich et al. JOURNAL OF HEPATOLOGY
- Sorting an LDL receptor with bound PCSK9 to intracellular degradation
- (2014) Trond P. Leren ATHEROSCLEROSIS
- The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion
- (2014) Camilla Gustafsen et al. Cell Metabolism
- Association of Low-Density Lipoprotein Cholesterol–Related Genetic Variants With Aortic Valve Calcium and Incident Aortic Stenosis
- (2014) J. Gustav Smith et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Fish Oil and Fenofibrate Prevented Phosphorylation-dependent Hepatic Sortilin 1 Degradation in Western Diet-fed Mice
- (2014) Jibiao Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CELSR2–PSRC1–SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort
- (2014) Prathima Arvind et al. Journal of Cardiology
- 1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue
- (2014) J. Baltes et al. JOURNAL OF CELL SCIENCE
- Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis
- (2014) Martin B. Mortensen et al. JOURNAL OF CLINICAL INVESTIGATION
- Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin
- (2014) Esben M. Quistgaard et al. PROTEIN SCIENCE
- A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm
- (2013) Gregory T. Jones et al. HUMAN MOLECULAR GENETICS
- Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis
- (2013) Roland Klingenberg et al. JOURNAL OF CLINICAL INVESTIGATION
- A genome-wide association study of a coronary artery disease risk variant
- (2013) Ji-Young Lee et al. JOURNAL OF HUMAN GENETICS
- Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice
- (2013) Lipeng Bi et al. JOURNAL OF LIPID RESEARCH
- The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid- Peptide in the Brain
- (2013) A.-S. Carlo et al. JOURNAL OF NEUROSCIENCE
- Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Can Mediate Degradation of the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)
- (2013) Maryssa Canuel et al. PLoS One
- Mutations in the SORT1 gene are unlikely to cause autosomal dominant hypercholesterolemia
- (2012) Kristian Tveten et al. ATHEROSCLEROSIS
- Transferability and Fine Mapping of genome-wide associated loci for lipids in African Americans
- (2012) Adebowale Adeyemo et al. BMC Medical Genetics
- The Sorting Receptor Sortilin Exhibits a Dual Function in Exocytic Trafficking of Interferon-γ and Granzyme A in T Cells
- (2012) Stefanie Herda et al. IMMUNITY
- Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism
- (2012) Alanna Strong et al. JOURNAL OF CLINICAL INVESTIGATION
- Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice
- (2012) Ding Ai et al. JOURNAL OF CLINICAL INVESTIGATION
- A Replication Study of GWAS-Derived Lipid Genes in Asian Indians: The Chromosomal Region 11q23.3 Harbors Loci Contributing to Triglycerides
- (2012) Timothy R. Braun et al. PLoS One
- Dynamics of Rab7b-Dependent Transport of Sorting Receptors
- (2012) Cinzia Progida et al. TRAFFIC
- Association of SNP rs17465637 on Chromosome 1q41 and rs599839 on 1p13.3 with Myocardial Infarction in an American Caucasian Population
- (2011) Annabel Z. Wang et al. ANNALS OF HUMAN GENETICS
- Circulating Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Regulates VLDLR Protein and Triglyceride Accumulation in Visceral Adipose Tissue
- (2011) Anna Roubtsova et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Evaluation of the gene–age interactions in HDL cholesterol, LDL cholesterol, and triglyceride levels: The impact of the SORT1 polymorphism on LDL cholesterol levels is age dependent
- (2011) Brian H. Shirts et al. ATHEROSCLEROSIS
- Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction
- (2011) Christopher J. O'Donnell et al. CIRCULATION
- Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration
- (2011) Aspasia Angelakopoulou et al. EUROPEAN HEART JOURNAL
- BACE1 Retrograde Trafficking Is Uniquely Regulated by the Cytoplasmic Domain of Sortilin
- (2011) Gina M. Finan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The 1p13.3 LDL (C)-Associated Locus Shows Large Effect Sizes in Young Populations
- (2011) Joseph M Devaney et al. PEDIATRIC RESEARCH
- Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking
- (2010) Ekyune Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sort1, Encoded by the Cardiovascular Risk Locus 1p13.3, Is a Regulator of Hepatic Lipoprotein Export
- (2010) Mads Kjolby et al. Cell Metabolism
- Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin
- (2010) A. Wahe et al. JOURNAL OF CELL SCIENCE
- Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor Heterodimer
- (2010) J. V. Larsen et al. MOLECULAR AND CELLULAR BIOLOGY
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
- (2010) Kiran Musunuru et al. NATURE
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus
- (2010) Fadel Tissir et al. NATURE NEUROSCIENCE
- Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin
- (2010) Fenghua Hu et al. NEURON
- Significant impact of chromosomal locus 1p13.3 on serum LDL cholesterol and on angiographically characterized coronary atherosclerosis
- (2009) Axel Muendlein et al. ATHEROSCLEROSIS
- Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease
- (2009) Patrick Linsel-Nitschke et al. ATHEROSCLEROSIS
- The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes
- (2009) Jibin Zeng et al. EXPERIMENTAL CELL RESEARCH
- Large scale replication analysis of loci associated with lipid concentrations in a Japanese population
- (2009) K Nakayama et al. JOURNAL OF MEDICAL GENETICS
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
- (2009) Sekar Kathiresan et al. NATURE GENETICS
- Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain
- (2009) Esben M Quistgaard et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- GGA Autoinhibition Revisited
- (2009) Jacob F. Cramer et al. TRAFFIC
- Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia
- (2008) Chris Wallace et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Endocytosis of Apolipoprotein A-V by Members of the Low Density Lipoprotein Receptor and the Vps10p Domain Receptor Families
- (2008) Stefan K. Nilsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LDL-cholesterol concentrations: a genome-wide association study
- (2008) Manjinder S Sandhu et al. LANCET
- Common variants at 30 loci contribute to polygenic dyslipidemia
- (2008) Sekar Kathiresan et al. NATURE GENETICS
- Newly identified loci that influence lipid concentrations and risk of coronary artery disease
- (2008) Cristen J Willer et al. NATURE GENETICS
- Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
- (2008) Sekar Kathiresan et al. NATURE GENETICS
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- (2008) Eric E Schadt et al. PLOS BIOLOGY
- AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes
- (2007) Maryssa Canuel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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