4.8 Editorial Material

The Yolk Sac Feeds Pancreatic Tumors

期刊

IMMUNITY
卷 47, 期 2, 页码 217-218

出版社

CELL PRESS
DOI: 10.1016/j.immuni.2017.07.021

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资金

  1. Medical Research Council [MR/N022556/1, G1002033] Funding Source: Medline
  2. MRC [MR/N022556/1] Funding Source: UKRI

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In this issue of Immunity, Zhu et al. (2017) report that tumor-associated macrophages in a mouse model of pancreatic ductal adenocarcinoma (PDAC) originate from both the yolk sac (YS) and bone marrow. Differential ablation of these populations indicates that only the YS-derived macrophages promote PDAC progression and growth.

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