Article
Clinical Neurology
Lin-Lin Han, Lan Wang, Zhi-Heng Xu, Xiao-Niu Liang, Meng-Wei Zhang, Yun Fan, Yi-Min Sun, Feng-Tao Liu, Wen-Bo Yu, Yi-Lin Tang
Summary: Parkinson's disease patients with subjective cognitive complaint (PD-SCC) exhibit faster deterioration of depression and quality of life than those with normal cognition. Subjective cognitive complaint may serve as an indicator of initial attention and executive function decline in Parkinson's disease.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2021)
Article
Neurosciences
Hua-Hsuan Sun, Mei-Yin Lin, Rui Nouchi, Pei-Ning Wang, Chia-Hsiung Cheng
Summary: Individuals with subjective memory complaints show deficits in automatic inhibitory function at the neurophysiological level, despite normal performance on cognitive tests. This suggests that altered brain function may occur prior to the onset of subjective memory complaints.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Review
Cell Biology
Tara Warren, Roisin McAllister, Amy Morgan, Taranjit Singh Rai, Victoria McGilligan, Matthew Ennis, Christopher Page, Catriona Kelly, Aaron Peace, Bernard M. Corfe, Mark Mc Auley, Steven Watterson
Summary: The overlap between vitamin D and cholesterol metabolism pathways is significant, yet our understanding of their independent and co-regulation is limited. Research highlights the relationships between vitamin D supplementation, total cholesterol, and LDL-C status, as well as the consistency between latitude, vitamin D, and cholesterol status. Furthermore, some results cannot be explained with current knowledge of molecular mechanisms.
Article
Clinical Neurology
Kelsey R. Thomas, Alexandra J. Weigand, Lauren C. Edwards, Emily C. Edmonds, Katherine J. Bangen, Gema Ortiz, Kayla S. Walker, Mark W. Bondi
Summary: This study examines differences in tau PET levels between individuals with subjective memory complaint (SMC) and objective subtle cognitive decline (Obj-SCD). The results show that Obj-SCD+ participants had higher tau levels and rates of tau positivity compared to Obj-SCD- participants, while SMC groups did not differ in tau levels. Additionally, there was very little agreement between SMC and Obj-SCD classifications.
ALZHEIMERS RESEARCH & THERAPY
(2022)
Article
Neurosciences
Young Min Choe, Guk-Hee Suh, Boung Chul Lee, Ihn-Geun Choi, Jun Ho Lee, Hyun Soo Kim, Jaeuk Hwang, Jee Wook Kim
Summary: The study found that in older adults without dementia, subjective memory complaints (SMC) of feeling worse memory performance than others in a similar age group were associated with poor objective cognitive performance and this association was mediated by increased brain amyloid index (API).
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Nutrition & Dietetics
Sreedhar Subramanian, Jonathan M. Rhodes, Joseph M. Taylor, Anna M. Milan, Steven Lane, Martin Hewison, Rene F. Chun, Andrea Jorgensen, Paul Richardson, Darshan Nitchingham, Joseph Aslan, Maya Shah, Coonoor R. Chandrasekar, Amanda Wood, Mike Beadsworth, Munir Pirmohamed
Summary: Vitamin D status is not significantly associated with mortality from COVID-19, but extremely low and high levels may be associated with mortality risks.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Nutrition & Dietetics
Shahid Hussain, Clayton Yates, Moray J. Campbell
Summary: The biological actions of the vitamin D receptor (VDR) have been extensively studied, with roles identified in calcium regulation, cell differentiation, and metabolism. Applying systems biology approaches can provide a more precise understanding of the biological functions of VDR. Top-down analysis of genome-wide data reveals the central role of VDR in biological networks, while bottom-up modeling can explain its function and identify unknown mechanisms.
Article
Biochemistry & Molecular Biology
Nazli Ecem Dal-Bekar, Gul Huray Islekel, Aydan Koken-Avsar, Handan Yarkan-Tugsal, Gamze Tuna, Berrin Zengin, Ahmet Merih Birlik
Summary: Scleroderma is a rare autoimmune disease characterized by progressive fibrosis of the skin and internal organs. Oxidative damage and vitamin D deficiency play important roles in the development of scleroderma. This study comprehensively investigated oxidative DNA damage in scleroderma and evaluated the effects of vitamin D supplementation.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)
Article
Medicine, General & Internal
Hong Su, Haina Wang, Lina Meng
Summary: The study demonstrates that Baduanjin exercise is effective in improving subjective memory complaints among older adults, as well as enhancing memory function, executive function, and general self-efficacy levels.
Article
Neurosciences
Arturo Xose Pereiro, Sonia Valladares-Rodriguez, Alba Felpete, Cristina Lojo-Seoane, Maria Campos-Magdaleno, Sabela Carme Mallo, David Facal, Luis Anido-Rifon, Sylvie Belleville, Onesimo Juncos-Rabadan
Summary: The study found that differentiation based on severity of subjective cognitive complaints (SCCs) in subjective cognitive decline (SCD) can effectively predict cognitive decline progression. Factors such as memory, cognitive reserve, general health, and diagnostic stability play a significant role in the predictive algorithm.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Clinical Neurology
Shaozhen Ji, Hong Sun, Xianglan Jin, Baoxin Chen, Jing Zhou, Jiayi Zhao, Xiao Liang, Wei Shen, Yunling Zhang, Piu Chan
Summary: This study investigated cognitive outcomes in patients with post-stroke subjective cognitive complaints (SCC) within 1 year after stroke and identified factors associated with cognitive recovery. It found that some patients experienced cognitive recovery after stroke, but those with a higher education level reporting SCC earlier had poorer cognitive recovery. Male sex, higher baseline MoCA scores, coffee intake, and thalamus lesions appeared to independently predict cognitive recovery.
FRONTIERS IN NEUROLOGY
(2022)
Article
Pharmacology & Pharmacy
F. Alhussain, M. Alomar, A. Alenazi, M. Aldraihem, L. Alshiha, S. Bashir
Summary: The study aimed to investigate the relationship between vitamin D levels and cognitive function in MS patients. Results showed impaired cognitive performance in MS patients, with vitamin D deficiency potentially predicting cognitive impairment independently.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Nutrition & Dietetics
Beatrice Arosio, Paolo Dionigi Rossi, Evelyn Ferri, Matteo Cesari, Giovanni Vitale
Summary: Vitamin D levels are significantly associated with cognitive decline, with the lowest levels seen in dementia patients and higher levels in mild cognitive impairment patients.
Review
Geriatrics & Gerontology
Juan Huang, Xingxing Yuan, Lin Chen, Binbin Hu, Lijuan Jiang, Ting Shi, Hui Wang, Wei Huang
Summary: Cognitive impairment in Parkinson's disease worsens prognosis and causes burdens for caregivers and economic consequences. Subjective cognitive decline (SCD) has been regarded as an at-risk state for mild cognitive impairment (MCI) and a prodromal stage for dementia in Alzheimer's disease (AD). However, there is a lack of consensus on the definition and evaluation of SCD in Parkinson's disease (PD). This review found an association between PD-SCD and objective cognitive function, suggesting the importance of establishing a guideline for defining and evaluating SCD in PD.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Clinical Neurology
Sujuan Li, Xuelei Xu, Yan Qiu, Ziwei Teng, Jieyu Liu, Hui Yuan, Jindong Chen, Yuxi Tan, Min Yang, Kun Jin, Baoyan Xu, Hui Tang, Ziru Zhao, Bolun Wang, Hui Xiang, Haishan Wu
Summary: This study found that patients with bipolar disorder have higher levels of vitamin D in their serum and these levels are negatively associated with cognitive impairment. For patients with bipolar disorder, more physical activity is less beneficial to cognition than longer resting.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
