期刊
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
卷 64, 期 1, 页码 4-15出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TBME.2016.2605451
关键词
Acoustic measurements; interferometry; optical resonators; optical sensors; photoacoustic (PA) imaging
资金
- National Institutes of Health [1R01EY019951, 1R24EY022883]
- National Science Foundation [CBET-1055379, DBI-1353952, CBET-1066776, CMMI-0955195, CMMI-0751621]
- Div Of Biological Infrastructure
- Direct For Biological Sciences [1353952] Funding Source: National Science Foundation
Objective: Photoacoustic (PA) imaging emerges as a unique biological samples based on optical absorption contrast. In PA imaging, piezoelectric transducers are commonly used to detect laser-induced ultrasonic waves. However, they typically lack adequate broadband sensitivity at ultrasonic frequency higher than 100 MHz, whereas their bulky size and optically opaque nature cause technical difficulties in integrating PA imaging with conventional optical imaging modalities. To overcome these limitations, optical methods of ultrasound detection were developed and shown their unique applications in PA imaging. Methods: We provide an overview of recent technological advances in optical methods of ultrasound detection and their applications in PA imaging. A general theoretical framework describing sensitivity, bandwidth, and angular responses of optical ultrasound detection is also introduced. Results: Optical methods of ultrasound detection can provide improved detection angle and sensitivity over significantly extended bandwidth. In addition, its versatile variants also offer additional advantages, such as device miniaturization, optical transparency, mechanical flexibility, minimal electrical/ mechanical crosstalk, and potential noncontact PA imaging. Conclusion: The optical ultrasound detection methods discussed in this review and their future evolution may play an important role in PA imaging for biomedical study and clinical diagnosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据