Article
Health Care Sciences & Services
Dylan M. Richards, MacKenzie J. Tweardy, Steven R. Steinhubl, David W. Chestek, Terry L. Vanden Hoek, Karen A. Larimer, Stephan W. Wegerich
Summary: The COVID-19 pandemic has accelerated the adoption of innovative healthcare methods, with the development and validation of a COVID-19 decompensation index (CDI) model based on chest patch-derived continuous sensor data showing promising results for predicting COVID-19 hospitalizations in outpatient-managed COVID-19 positive individuals. The machine learning model outperformed standard of care modalities in terms of both event identification and false alarm rate, representing a potential application of machine learning in continuous remote patient monitoring systems.
NPJ DIGITAL MEDICINE
(2021)
Article
Engineering, Electrical & Electronic
Sukhpreet Singh, Michal Kozlowski, Irene Garcia-Lopez, Zhou Jiang, Esther Rodriguez-Villegas
Summary: This study introduces a neck-worn photoplethysmography system for monitoring cardiac and respiratory responses during sleep. The system was compared to a gold-standard commercial multichannel cardiorespiratory polysomnography system to demonstrate its accuracy in measuring heart rate, respiratory rate, and peripheral blood oxygen saturation. The findings show that the neck-based system is able to accurately detect vital signs during sleep, making it a viable option for minimally invasive monitoring.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2021)
Article
Computer Science, Information Systems
Celal Savur, Ruslan Dautov, Kamil Bukum, Xiaojuan Xia, Jean-Philippe Couderc, Gill R. Tsouri
Summary: We propose a new framework for passive monitoring of pulse rate during users' time on their personal mobile devices. The framework captures pulse signals using the front-facing camera while the user is interacting with the device in a normal manner. It does not require subject participation, addressing the problem of low adherence. Various techniques, including signal processing, machine learning classifiers, and deep learning methods, are investigated to suppress user motion and ambient light fluctuations. Clinical study results show that the proposed framework accurately monitors pulse rate, providing a gateway for long-term monitoring without subject participation or dedicated wearable devices.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2023)
Article
Chemistry, Analytical
Brian S. Bradke, Tiffany A. Miller, Bradford Everman
Summary: A new PPG sensor device, SPYDR, was tested for high-motion, high-pressure, low-oxygen, and high-G-force environments. Results showed that SPYDR provided accurate and reliable physiological monitoring in dynamic high-risk environments compared to other sensors, producing high-fidelity data.
Article
Chemistry, Analytical
Valerie A. A. van Es, Richard G. P. Lopata, Enzo Pasquale Scilingo, Mimma Nardelli
Summary: Despite advancements in remote photoplethysmography (rPPG), extracting a reliable pulse rate variability (PRV) signal remains challenging. This study compared eight image-based photoplethysmography (iPPG) methods for pulse rate (PR) and PRV feature extraction. The algorithms were tested on a public dataset, and their performances were evaluated using statistical analysis. The study found that the POS and CHROM techniques were the most robust for PR estimation and assessing autonomic nervous system (ANS) dynamics. It also demonstrated that the Poincare map of PRV series derived from the POS and CHROM methods can reliably characterize vagal tone. This study supports the use of iPPG systems for obtaining clinically useful information about ANS dynamics.
Article
Biochemical Research Methods
Stefan Borik, Patrik Procka, Jakub Kubicek, Christoph Hoog Antink
Summary: The spatial mapping of skin perfusion provides essential information about physiological processes. A hardware device is proposed to modulate the reference biosignal into the audio frequency band, allowing digital cameras or smartphones to be transformed into PPGI measurement systems. This solution enables the synchronous recording of PPGI and other reference signals.
BIOMEDICAL OPTICS EXPRESS
(2022)
Review
Physiology
Nunzia Molinaro, Emiliano Schena, Sergio Silvestri, Fabrizio Bonotti, Damiano Aguzzi, Erika Viola, Fabio Buccolini, Carlo Massaroni
Summary: The measurement of physiological parameters is crucial for assessing health status. Contactless monitoring of vital signs using camera-based systems in the visible range has shown potential in estimating vital signs. Digital cameras can be used as an unobtrusive and easy-to-use technology for monitoring physiological signs.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Pediatrics
Anup C. Katheria, Ana Morales, Sanjay Shashank, Wade D. Rich, Neil N. Finer
Summary: Current guidelines recommend using a cardiac monitor during neonatal resuscitation. Infants assigned to a novel electrocardiogram algorithm had a faster heart rate compared to the conventional algorithm. Although the resuscitation outcomes did not differ, the availability of an earlier heart rate may be beneficial for neonatal providers during high-risk resuscitations.
JOURNAL OF PEDIATRICS
(2022)
Review
Chemistry, Analytical
Ana M. Cabanas, Macarena Fuentes-Guajardo, Katina Latorre, Dayneri Leon, Pilar Martin-Escudero
Summary: Pulse oximetry is widely used in primary and intensive care units, especially during the COVID-19 pandemic. However, factors such as skin color can affect its accuracy. Recent studies have found a positive bias in oxygen saturation measurements in patients with darkly pigmented skin. This review aims to assess the influence of skin pigmentation on the accuracy of pulse oximetry through a systematic review.
Article
Chemistry, Multidisciplinary
Zhifang Du, Hoang Mai Luong, Sina Sabury, Austin L. Jones, Ziyue Zhu, Patchareepond Panoy, Sangmin Chae, Ahra Yi, Hyo Jung Kim, Steven Xiao, Viktor V. Brus, G. N. Manjunatha Reddy, John R. Reynolds, Thuc-Quyen Nguyen
Summary: This paper reports a record-breaking organic photodetector system processed from 2-methyltetrahydrofuran, which exhibits high light detectivity and can be used in medical applications in wearable devices.
ADVANCED MATERIALS
(2023)
Article
Health Care Sciences & Services
Andrea Torres-Robles, Karen Allison, Simon K. Poon, Miranda Shaw, Owen Hutchings, Warwick J. Britton, Andrew Wilson, Melissa Baysari
Summary: This study explores the use, performance, and acceptability of a pulse oximeter for remote monitoring during COVID-19. The results show that both patients and clinicians had positive perceptions of the device, considering it highly acceptable and easy to use. However, some factors such as patient age and device-related characteristics may negatively impact its accuracy.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Agriculture, Dairy & Animal Science
Elzbieta Stefanik, Olga Drewnowska, Barbara Lisowska, Bernard Turek
Summary: Horses are challenging to anaesthetize due to physiological factors, leading to intraoperative gas exchange disturbances and higher post-operative complications and mortality rates compared to other companion animals. Monitoring methods may not be sufficient alone and combining them is necessary to assess the patient's condition comprehensively. New methods like near-infrared spectroscopy (NIRS) show promise in improving gas monitoring during general anaesthesia in horses.
Letter
Medicine, General & Internal
Kathleen C. Lee, Anna U. Morgan, Krisda H. Chaiyachati, David A. Asch, Ruiying A. Xiong, David Do, Austin S. Kilaru, Doreen Lam, Andrew Parambath, Ari B. Friedman, Zachary F. Meisel, Christopher K. Snider, Deena L. Chisholm, Sheila Kelly, Jessica E. Hemmons, Dina Abdel-Rahman, Jeffrey Ebert, Medha Ghosh, Julianne Reilly, Christina J. O'Malley, Lauren Hahn, Nancy M. Mannion, Ann M. Huffenberger, Susan McGinley, Mohan Balachandran, Neda Khan, Judy A. Shea, Nandita Mitra, M. Kit Delgado
Summary: Adding pulse oximetry to symptom-based remote monitoring did not improve survival rates for nonhospitalized Covid-19 patients.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Chemistry, Analytical
Su-Gyeong Yu, So-Eui Kim, Na Hye Kim, Kun Ha Suh, Eui Chul Lee
Summary: Pulse rate variability (PRV) is an indicator of an individual's autonomic nervous system health status, measured using photoplethysmography (PPG) signals. The study showed that PRV analysis performed with lab-based RPPG technology yielded results comparable in quality to analysis via CPPG, with similar temporal and frequency parameters extracted.
Article
Chemistry, Multidisciplinary
Adam Nagy, Peter Foldesy, Imre Janoki, Daniel Terbe, Mate Siket, Miklos Szabo, Judit Varga, Akos Zarandy
Summary: Non-contact visual monitoring of vital signs in neonatology has been studied in ideal scenarios, but motion artifacts and interference in real care situations may affect the accuracy of measurements; the proposed algorithms can detect and classify different conditions, and can measure vital signs using a single camera, maintaining computational efficiency.
APPLIED SCIENCES-BASEL
(2021)
Editorial Material
Anesthesiology
Panicos A. Kyriacou, Peter H. Charlton, Raghda Al-Halawani, Kirk H. Shelley
Summary: Recent reports discuss the inaccuracies of pulse oximetry in patients with varying degrees of skin pigmentation. We provide a summary of literature, discuss potential clinical implications, and suggest ways to improve pulse oximetry to address these shortcomings.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Primary Health Care
Laura C. Armitage, Shaun Davidson, Adam Mahdi, Mirae Harford, Richard McManus, Andrew Farmer, Peter Watkinson, Lionel Tarassenko
Summary: The study emphasizes the importance of measuring night-time blood pressure when assessing individuals for hypertension. It found that not measuring night-time blood pressure puts reverse dippers (those with a rise in blood pressure at night) at risk of failure to diagnose hypertension. Therefore, it is recommended that general practitioners offer ambulatory blood-pressure monitoring (ABPM) to all patients aged >= 60 years as a minimum when assessing for hypertension.
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Article
Critical Care Medicine
James C. Doidge, Doug W. Gould, Zia Sadique, Mark Borthwick, Robert A. Hatch, Fergus J. Caskey, Lui Forni, Robert F. Lawrence, Clare MacEwan, Marlies Ostermann, Paul R. Mouncey, David A. Harrison, Kathryn M. Rowan, J. Duncan Young, Peter J. Watkinson
Summary: This study evaluated the clinical and health economic impacts of transitioning from systemic heparin anticoagulation (SHA) to regional citrate anticoagulation (RCA) for continuous kidney replacement therapy (CKRT) in intensive care units (ICUs). The results showed that transition to RCA was not associated with changes in mortality, but was associated with increases in kidney support duration, advanced cardiovascular support duration, and ICU length of stay.
JOURNAL OF CRITICAL CARE
(2023)
Review
Cardiac & Cardiovascular Systems
Rachel E. Climie, Jordi Alastruey, Christopher C. Mayer, Achim Schwarz, Agne Laucyte-Cibulskiene, Julija Voicehovska, Elisabetta Bianchini, Rosa-Maria Bruno, Peter H. Charlton, Andrea Grillo, Andrea Guala, Magid Hallab, Bernhard Hametner, Piotr Jankowski, Karsten Konigstein, Anna Lebedeva, Ioana Mozos, Giacomo Pucci, Houry Puzantian, Dimitrios Terentes-Printzios, Gunay Yetik-Anacak, Chloe Park, Peter M. Nilsson, Thomas Weber
Summary: Prevention of cardiovascular disease (CVD) is a major public health challenge. Identifying individuals at increased cardiovascular risk at an asymptomatic stage is crucial for minimizing disease progression and burden. Vascular ageing (VA) is the deterioration of vascular structure and function over time and can help identify those at elevated cardiovascular risk. However, VA is seldom measured in routine clinical practice due to lack of consensus and practical issues. This state-of-the-art review aims to increase knowledge about VA and promote its routine measurement.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Computer Science, Information Systems
Kevin Kotzen, Peter H. Charlton, Sharon Salabi, Lea Amar, Amir Landesberg, Joachim A. Behar
Summary: Staging is crucial in diagnosing sleep disorders and managing sleep health. This study proposes an automated approach using raw photoplethysmography (PPG) time series and deep learning for four-class sleep staging. The developed SleepPPG-Net model achieves state-of-the-art performance and opens possibilities for the development of wearable devices for clinical applications.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2023)
Article
Cardiac & Cardiovascular Systems
Tove Hygrell, Fredrik Viberg, Erik Dahlberg, Peter H. Charlton, Katrin Kemp Gudmundsdottir, Jonathan Mant, Josef Lindman Hornlund, Emma Svennberg
Summary: The study aimed to observe the accuracy of an artificial intelligence-based network in predicting paroxysmal atrial fibrillation from a normal sinus rhythm single-lead ECG. The algorithm performed well in predicting paroxysmal AF in a wide age range, but had lower performance in age-homogeneous groups.
Review
Biophysics
Raghda Al-Halawani, Peter H. Charlton, Meha Qassem, Panayiotis A. Kyriacou
Summary: Pulse oximetry is a non-invasive optical technique used to measure arterial oxygen saturation (SpO(2)) in various clinical settings. However, its accuracy may vary in individuals with different skin pigmentations, with decreased accuracy in patients with dark skin. Addressing these inaccuracies can potentially improve clinical outcomes.
PHYSIOLOGICAL MEASUREMENT
(2023)
Article
Chemistry, Analytical
Mantas Rinkevicius, Peter H. H. Charlton, Raquel Bailon, Vaidotas Marozas
Summary: Low-quality PPG signals can lead to inaccurate estimation of PAT during PSG studies. This study developed a PPG signal-quality assessment algorithm and used ECG signals to evaluate the PPG signal quality and investigate its influence on PAT. The results showed that lower PPG signal quality was associated with larger differences in PAT, and using a PPG signal quality-based PAT evaluation method reduced deviations and allowed for larger differences between different sleep stages and events.
Article
Nursing
Jody Ede, M. Clarete, I. Taylor, C. Taylor, B. Kent, P. Watkinson, R. Endacott
NURSING IN CRITICAL CARE
(2023)
Article
Multidisciplinary Sciences
Niall Jackson, Jessica Woods, Peter Watkinson, Andrew Brent, Tim E. A. Peto, A. Sarah Walker, David W. Eyre
Summary: This study aimed to evaluate the frequency of value preferences in recording vital signs in electronic healthcare records (EHRs) and the factors associated with it. Data from Oxford University Hospitals, UK, were analyzed to determine the prevalence of value preferences in blood pressure, heart rate, respiratory rate, and temperature measurements. The study found that there were discrepancies in the recorded values, particularly in temperature measurements. Digit preference and temperature recordings of 36.0 degrees C were more common in certain patient groups and hospital settings. This highlights the need for accurate documentation and adjustments in patient care and research analysis.
SCIENTIFIC REPORTS
(2023)
Review
Medicine, General & Internal
Kara G. Fields, Jie Ma, Tatjana Petrinic, Hassan Alhassan, Anthony Eze, Ankith Reddy, Mona Hedayat, Rui Providencia, Gregory Y. H. Lip, Jonathan P. Bedford, David A. Clifton, Oliver C. Redfern, Benjamin O'Brien, Peter J. Watkinson, Gary S. Collins, Jochen D. Muehlschlegel
Summary: This systematic review aims to critically appraise the methodology and risk of bias in the development and validation of multivariable prediction models for atrial fibrillation after cardiac surgery (AFACS). The findings will be disseminated to improve future studies and provide a clinically useful risk estimation tool.
Review
Cardiac & Cardiovascular Systems
Jordi Alastruey, Peter H. Charlton, Vasiliki Bikia, Birute Paliakaite, Bernhard Hametner, Rosa Maria Bruno, Marijn P. Mulder, Samuel Vennin, Senol Piskin, Ashraf W. Khir, Andrea Guala, Christopher C. Mayer, Jonathan Mynard, Alun D. Hughes, Patrick Segers, Berend E. Westerhof
Summary: Arterial pulse waves (PWs), such as blood pressure and photoplethysmogram (PPG) signals, are rich sources of information for assessing vascular age and identifying individuals at elevated cardiovascular risk. This review explores the possibilities and limitations of reduced-order biophysical models and theoretical and empirical methods for analyzing PW signals and extracting clinically relevant information. Detailed mathematical derivations are provided, demonstrating the relationships between these models and methods. Suggestions for future research are also outlined to fully utilize the potential of modeling and analyzing PW signals for accurate vascular age assessment.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Article
Neurosciences
Charlotte H. Harrison, Maxime Taquet, Paul J. Harrison, Peter J. Watkinson, Matthew J. Rowland
Summary: This study examines the antecedent characteristics of non-traumatic subarachnoid hemorrhage (SAH) patients, compares the risk of SAH between women and men, and investigates if this changes with age. The results show that men have a higher risk of SAH than women overall, particularly in younger adults. However, in the age group over 75 years, women have a higher risk of SAH compared to men.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2023)
Letter
Hematology
Simon J. Stanworth, Akshay Shah, James Doidge, Peter Watkinson
TRANSFUSION MEDICINE
(2023)
Correction
Cardiac & Cardiovascular Systems
Rachel E. Climie, Jordi Alastruey, Christopher C. Mayer, Achim Schwarz, Agne Laucyte-Cibulskiene, Julija Voicehovska, Elisabetta Bianchini, Rosa-Maria Bruno, Peter H. Charlton, Andrea Grillo, Andrea Guala, Magid Hallab, Bernhard Hametner, Piotr Jankowski, Karsten Konigstein, Anna Lebedeva, Ioana Mozos, Giacomo Pucci, Houry Puzantian, Dimitrios Terentes-Printzios, Gunay Yetik-Anacak, Chloe Park, Peter M. Nilsson, Thomas Weber
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)