Whole-protein alanine-scanning mutagenesis of allostery: A large percentage of a protein can contribute to mechanism

What Mutagenesis Can and Cannot Reveal About Allostery

(2016) Gerald M. Carlson et al.   BIOPHYSICAL JOURNAL

Distinguishing the Interactions in the Fructose 1,6-Bisphosphate Binding Site of Human Liver Pyruvate Kinase That Contribute to Allostery

(2015) Arjun Ishwar et al.   BIOCHEMISTRY

Sites Involved in Intra- and Interdomain Allostery Associated with the Activation of Factor VIIa Pinpointed by Hydrogen-Deuterium Exchange and Electron Transfer Dissociation Mass Spectrometry

(2014) Hongjian Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitric Oxide-Induced Conformational Changes in Soluble Guanylate Cyclase

(2014) Eric S. Underbakke et al.   STRUCTURE

Identification of Regions of Rabbit Muscle Pyruvate Kinase Important for Allosteric Regulation by Phenylalanine, Detected by H/D Exchange Mass Spectrometry

(2013) Charulata B. Prasannan et al.   BIOCHEMISTRY

Investigating Models of Protein Function and Allostery With a Widespread Mutational Analysis of a Light-Activated Protein

(2013) Josiah P. Zayner et al.   BIOPHYSICAL JOURNAL

PDBsum additions

(2013) Tjaart A. P. de Beer et al.   NUCLEIC ACIDS RESEARCH

Activation of AMP-Activated Protein Kinase Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry

(2013) Rachelle R. Landgraf et al.   STRUCTURE

Distinguishing the Chemical Moiety of Phosphoenolpyruvate That Contributes to Allostery in Muscle Pyruvate Kinase

(2012) James M. Urness et al.   BIOCHEMISTRY

Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase

(2012) Todd Holyoak et al.   BIOCHEMISTRY

Effector Analogues Detect Varied Allosteric Roles for Conserved Protein−Effector Interactions in Pyruvate Kinase Isozymes

(2011) Aileen Y. Alontaga et al.   BIOCHEMISTRY

DEPTH: a web server to compute depth and predict small-molecule binding cavities in proteins

(2011) Kuan Pern Tan et al.   NUCLEIC ACIDS RESEARCH

The pH dependence of the allosteric response of human liver pyruvate kinase to fructose-1,6-bisphosphate, ATP, and alanine

(2009) Aron W. Fenton et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

An Activating Interaction between the Unphosphorylated N-Terminus of Human Liver Pyruvate Kinase and the Main Body of the Protein Is Interrupted by Phosphorylation

(2009) Aron W. Fenton et al.   BIOCHEMISTRY

Mapping of the Allosteric Network in the Regulation of α-Isopropylmalate Synthase fromMycobacterium tuberculosisby the Feedback Inhibitorl-Leucine: Solution-Phase H/D Exchange Monitored by FT-ICR Mass Spectrometry

(2009) Patrick A. Frantom et al.   BIOCHEMISTRY

Allostery: an illustrated definition for the ‘second secret of life’

(2008) Aron W. Fenton   TRENDS IN BIOCHEMICAL SCIENCES