Depolarization causes the formation of a ternary complex between GlialCAM, MLC1 and ClC-2 in astrocytes: implications in megalencephalic leukoencephalopathy

Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes

(2016) Angela Lanciotti et al.   HUMAN MOLECULAR GENETICS

Discovery of CLC transport proteins: cloning, structure, function and pathophysiology

(2015) Thomas J. Jentsch   JOURNAL OF PHYSIOLOGY-LONDON

Regulatory-auxiliary subunits of CLC chloride channel-transport proteins

(2015) Alejandro Barrallo-Gimeno et al.   JOURNAL OF PHYSIOLOGY-LONDON

Secondary paroxysmal kinesigenic dyskinesia associated with CLCN2 gene mutation

(2015) Hasmet A. Hanagasi et al.   PARKINSONISM & RELATED DISORDERS

TMEM16, LRRC8A, bestrophin: chloride channels controlled by Ca2+ and cell volume

(2015) Karl Kunzelmann   TRENDS IN BIOCHEMICAL SCIENCES

Mice with megalencephalic leukoencephalopathy with cysts: A developmental angle

(2014) Mohit Dubey et al.   ANNALS OF NEUROLOGY

GlialCAM, a CLC-2 Cl - Channel Subunit, Activates the Slow Gate of CLC Chloride Channels

(2014) Elena Jeworutzki et al.   BIOPHYSICAL JOURNAL

Megalencephalic leukoencephalopathy with subcortical cysts protein 1 regulates glial surface localization of GLIALCAM from fish to humans

(2014) Sònia Sirisi et al.   HUMAN MOLECULAR GENETICS

Functional Analyses of Mutations inHEPACAMCausing Megalencephalic Leukoencephalopathy

(2014) Tanit Arnedo et al.   HUMAN MUTATION

Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: Relevance to MLC disease pathogenesis

(2014) Maria S. Brignone et al.   NEUROBIOLOGY OF DISEASE

Subclinical leukodystrophy and infertility in a man with a novel homozygous CLCN2 mutation

(2014) D. Di Bella et al.   NEUROLOGY

Regional Diversity and Developmental Dynamics of the AMPA-Receptor Proteome in the Mammalian Brain

(2014) Jochen Schwenk et al.   NEURON

Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents

(2013) Xavier Capdevila-Nortes et al.   HUMAN MOLECULAR GENETICS

Brain white matter oedema due to ClC-2 chloride channel deficiency: an observational analytical study

(2013) Christel Depienne et al.   LANCET NEUROLOGY

Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations

(2012) Angela Lanciotti et al.   HUMAN MOLECULAR GENETICS

Megalencephalic leukoencephalopathy with subcortical cysts: chronic white matter oedema due to a defect in brain ion and water homoeostasis

(2012) Marjo S van der Knaap et al.   LANCET NEUROLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

GlialCAM, a Protein Defective in a Leukodystrophy, Serves as a ClC-2 Cl− Channel Auxiliary Subunit

(2012) Elena Jeworutzki et al.   NEURON

Mutant GlialCAM Causes Megalencephalic Leukoencephalopathy with Subcortical Cysts, Benign Familial Macrocephaly, and Macrocephaly with Retardation and Autism

(2011) Tania López-Hernández et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts

(2011) Tania López-Hernández et al.   HUMAN MOLECULAR GENETICS

Extending the Dynamic Range of Label-free Mass Spectrometric Quantification of Affinity Purifications

(2011) Wolfgang Bildl et al.   MOLECULAR & CELLULAR PROTEOMICS

Knockdown of MLC1 in primary astrocytes causes cell vacuolation: A MLC disease cell model

(2011) Anna Duarri et al.   NEUROBIOLOGY OF DISEASE

The β1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis

(2010) Maria S. Brignone et al.   HUMAN MOLECULAR GENETICS

Extracellular high K+ stimulates vesicular glutamate release from astrocytes by activating voltage-dependent calcium channels

(2010) Takahiro Yaguchi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: Role of a tyrosine endocytosis motif in surface retrieval

(2009) Isabel Cornejo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system

(2009) J.E. Rash   NEUROSCIENCE

GlialCAM, an immunoglobulin-like cell adhesion molecule is expressed in glial cells of the central nervous system

(2008) Linda Favre-Kontula et al.   GLIA

Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects

(2008) A. Duarri et al.   HUMAN MOLECULAR GENETICS

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY