A comparison of ALK gene rearrangement and ALK protein expression in primary lung carcinoma and matched metastasis

Mutational status of synchronous and metachronous tumor samples in patients with metastatic non-small-cell lung cancer

(2016) Gilles Quéré et al.   BMC CANCER

Custom Gene Capture and Next-Generation Sequencing to Resolve Discordant ALK Status by FISH and IHC in Lung Adenocarcinoma

(2016) Jin Sung Jang et al.   Journal of Thoracic Oncology

ALK Protein Analysis by IHC Staining after Recent Regulatory Changes: A Comparison of Two Widely Used Approaches, Revision of the Literature, and a New Testing Algorithm

(2016) Antonio Marchetti et al.   Journal of Thoracic Oncology

Feasibility of cytological specimens for ALK fusion detection in patients with advanced NSCLC using the method of RT-PCR

(2016) Yan Wang et al.   LUNG CANCER

High concordance of ALK rearrangement between primary tumor and paired metastatic lymph node in patients with lung adenocarcinoma

(2016) Likun Hou et al.   Journal of Thoracic Disease

Cytopathology of pulmonary adenocarcinoma with a single histological pattern using the proposed International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society (IASLC/ATS/ERS) classification

(2015) Erika F. Rodriguez et al.   CANCER CYTOPATHOLOGY

French multicentric validation ofALKrearrangement diagnostic in 547 lung adenocarcinomas

(2015) Sylvie Lantuejoul et al.   EUROPEAN RESPIRATORY JOURNAL

Intratumoral Heterogeneity of ALK-Rearranged and ALK/EGFR Coaltered Lung Adenocarcinoma

(2015) Weijing Cai et al.   JOURNAL OF CLINICAL ONCOLOGY

Heterogeneity of Anaplastic Lymphoma Kinase Gene Rearrangement in Non–Small-Cell Lung Carcinomas: A Comparative Study Between Small Biopsy and Excision Samples

(2015) Hideyuki Abe et al.   Journal of Thoracic Oncology

Clinical Implications of Variant ALK FISH Rearrangement Patterns

(2015) Xin Gao et al.   Journal of Thoracic Oncology

ALK Testing in Lung Adenocarcinoma: Technical Aspects to Improve FISH Evaluation in Daily Practice

(2015) Vittoria Martin et al.   Journal of Thoracic Oncology

EML4-ALK Fusion Detected by RT-PCR Confers Similar Response to Crizotinib as Detected by FISH in Patients with Advanced Non-Small-Cell Lung Cancer

(2015) Yan Wang et al.   Journal of Thoracic Oncology

Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended

(2015) Spasenija Savic et al.   LUNG CANCER

Fluorescence In Situ Hybridization, Immunohistochemistry, and Next-Generation Sequencing for Detection of EML4-ALK Rearrangement in Lung Cancer

(2015) M. Pekar-Zlotin et al.   ONCOLOGIST

Correlation of Cytomorphology and Molecular Findings in EGFR+, KRAS+, and ALK+ Lung Carcinomas

(2014) Zaibo Li et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Immunohistochemistry, Fluorescence in Situ Hybridization, and Reverse Transcription–Polymerase Chain Reaction for the Detection of Anaplastic Lymphoma Kinase Gene Rearrangements in Patients With Non–Small Cell Lung Cancer: Potential Advantages and Methodologic Pitfalls

(2014) Irina Demidova et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Clinicopathologic characteristics of ALK rearrangements in primary lung adenocarcinoma with identified EGFR and KRAS status

(2014) Jinghui Wang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Prevalence and Clinical Outcomes for Patients With ALK-Positive Resected Stage I to III Adenocarcinoma: Results From the European Thoracic Oncology Platform Lungscape Project

(2014) Fiona H. Blackhall et al.   JOURNAL OF CLINICAL ONCOLOGY

Canadian Anaplastic Lymphoma Kinase Study: A Model for Multicenter Standardization and Optimization of ALK Testing in Lung Cancer

(2014) Jean-Claude Cutz et al.   Journal of Thoracic Oncology

A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material

(2014) John Le Quesne et al.   Journal of Thoracic Oncology

Multicenter Immunohistochemical ALK-Testing of Non–Small-Cell Lung Cancer Shows High Concordance after Harmonization of Techniques and Interpretation Criteria

(2014) Maximilian von Laffert et al.   Journal of Thoracic Oncology

An International Interpretation Study Using the ALK IHC Antibody D5F3 and a Sensitive Detection Kit Demonstrates High Concordance between ALK IHC and ALK FISH and between Evaluators

(2014) Murry W. Wynes et al.   Journal of Thoracic Oncology

Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology

(2013) Neal I. Lindeman et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Cytologic subtyping of lung adenocarcinoma by using the proposed International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society (IASLC/ATS/ERS) adenocarcinoma classification

(2013) Erika F. Rodriguez et al.   CANCER CYTOPATHOLOGY

ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non-Small Cell Lung Cancer

(2013) J. F. Gainor et al.   CLINICAL CANCER RESEARCH

Next-Generation Sequencing Reveals High Concordance of Recurrent Somatic Alterations Between Primary Tumor and Metastases From Patients With Non–Small-Cell Lung Cancer

(2013) Stéphane Vignot et al.   JOURNAL OF CLINICAL ONCOLOGY

MET and EGFR Mutations Identified in ALK-Rearranged Pulmonary Adenocarcinoma: Molecular Analysis of 25 ALK-Positive Cases

(2013) Jennifer M. Boland et al.   Journal of Thoracic Oncology

Combined Use of ALK Immunohistochemistry and FISH for Optimal Detection of ALK-Rearranged Lung Adenocarcinomas

(2013) Lynette M. Sholl et al.   Journal of Thoracic Oncology

Discordance between anaplastic lymphoma kinase status in primary non-small-cell lung cancers and their corresponding metastases

(2012) Hyojin Kim et al.   HISTOPATHOLOGY

Immunohistochemistry is a Reliable Screening Tool for Identification of ALK Rearrangement in Non–Small-Cell Lung Carcinoma and is Antibody Dependent

(2012) Chris M.J. Conklin et al.   Journal of Thoracic Oncology

Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study

(2012) D Ross Camidge et al.   LANCET ONCOLOGY

ALKoma: A Cancer Subtype with a Shared Target

(2012) Hiroyuki Mano   Cancer Discovery

Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma

(2011) Yasushi Yatabe et al.   JOURNAL OF CLINICAL ONCOLOGY

Evaluation of ALK Gene Status in Primary Lung Adenocarcinoma and Matched Metastases

(2011) Antonio Rossi et al.   Journal of Thoracic Oncology

Histologic subtypes, immunohistochemistry, FISH or molecular screening for the accurate diagnosis of ALK-rearrangement in lung cancer: A comprehensive study of Caucasian non-smokers

(2011) Pierre-Alexandre Just et al.   LUNG CANCER

KRAS mutation status in primary nonsmall cell lung cancer and matched metastases

(2010) Alexis B. Cortot et al.   CANCER

Optimizing the Detection of Lung Cancer Patients Harboring Anaplastic Lymphoma Kinase (ALK) Gene Rearrangements Potentially Suitable for ALK Inhibitor Treatment

(2010) D. R. Camidge et al.   CLINICAL CANCER RESEARCH

Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

(2010) Eunice L. Kwak et al.   NEW ENGLAND JOURNAL OF MEDICINE

EML4-ALK Rearrangement in Non-Small Cell Lung Cancer and Non-Tumor Lung Tissues

(2009) Maria Paola Martelli et al.   AMERICAN JOURNAL OF PATHOLOGY

EGFR/KRAS/BRAF Mutations in Primary Lung Adenocarcinomas and Corresponding Locoregional Lymph Node Metastases

(2009) K. Schmid et al.   CLINICAL CANCER RESEARCH

Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC

(2008) A Kalikaki et al.   BRITISH JOURNAL OF CANCER