Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

(2016) H. Efsun Arda et al.   Cell Metabolism

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice

(2016) Selvi Durmus et al.   DRUG RESISTANCE UPDATES

Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets

(2015) J. Tian et al.   GENETICS

SLC transporters as therapeutic targets: emerging opportunities

(2015) Lawrence Lin et al.   NATURE REVIEWS DRUG DISCOVERY

Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro

(2015) Kristine Kloster-Jensen et al.   TRANSPLANT INTERNATIONAL

Structural similarities and differences between the human and the mouse pancreas

(2015) Jurij Dolenšek et al.   Islets

The Furan Fatty Acid Metabolite CMPF Is Elevated in Diabetes and Induces β Cell Dysfunction

(2014) Kacey J. Prentice et al.   Cell Metabolism

OATP1B3 Is Expressed in Pancreatic  -Islet Cells and Enhances the Insulinotropic Effect of the Sulfonylurea Derivative Glibenclamide

(2013) H. E. Meyer zu Schwabedissen et al.   DIABETES

The SLCO (former SLC21) superfamily of transporters

(2013) Bruno Hagenbuch et al.   MOLECULAR ASPECTS OF MEDICINE

Modulation of OATP1B-Type Transporter Function Alters Cellular Uptake and Disposition of Platinum Chemotherapeutics

(2013) C. S. Lancaster et al.   MOLECULAR CANCER THERAPEUTICS

Organic Anion Transporting Polypeptides Expressed in Pancreatic Cancer May Serve As Potential Diagnostic Markers and Therapeutic Targets for Early Stage Adenocarcinomas

(2013) Amanda Hays et al.   PHARMACEUTICAL RESEARCH

 -Cell Mass and Turnover in Humans: Effects of obesity and aging

(2012) Y. Saisho et al.   DIABETES CARE

Vesicular Nucleotide Transporter-Mediated ATP Release Regulates Insulin Secretion

(2012) Jessica C. Geisler et al.   ENDOCRINOLOGY

A Cancer-Specific Variant of the SLCO1B3 Gene Encodes a Novel Human Organic Anion Transporting Polypeptide 1B3 (OATP1B3) Localized Mainly in the Cytoplasm of Colon and Pancreatic Cancer Cells

(2012) Nilay Thakkar et al.   MOLECULAR PHARMACEUTICS

Importance of oestrogen receptors to preserve functional β-cell mass in diabetes

(2012) Joseph P. Tiano et al.   Nature Reviews Endocrinology

Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes

(2012) Joseph P. Tiano et al.   Islets

The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in Cancer

(2011) Amanda Obaidat et al.   Annual Review of Pharmacology and Toxicology

Drug Transporters in Drug Efficacy and Toxicity

(2011) M.K. DeGorter et al.   Annual Review of Pharmacology and Toxicology

Mitochondrial T3 receptor p43 regulates insulin secretion and glucose homeostasis

(2011) Emilie Blanchet et al.   FASEB JOURNAL

Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity

(2011) Ute I. Schwarz et al.   Pharmacogenetics and Genomics

Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of Progression

(2011) Heather Pressler et al.   PLoS One

Functions of OATP1A and 1B transporters in vivo: insights from mouse models

(2011) Dilek Iusuf et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets

(2011) Evangelos Briasoulis et al.   OncoTargets and Therapy

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

(2010) Smitha Sreedharan et al.   BMC GENOMICS

The HMG-CoA Reductase Inhibitor Pravastatin Stimulates Insulin Secretion through Organic Anion Transporter Polypeptides

(2010) Michiaki Abe et al.   Drug Metabolism and Pharmacokinetics

Integrin α3, But Not β1, Regulates Islet Cell Survival and Function via PI3K/Akt Signaling Pathways

(2010) Mansa Krishnamurthy et al.   ENDOCRINOLOGY

Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine

(2010) Alexandra G. Ianculescu et al.   Molecular BioSystems

Alterations in Hepatic mRNA Expression of Phase II Enzymes and Xenobiotic Transporters after Targeted Disruption of Hepatocyte Nuclear Factor 4 Alpha

(2010) Hong Lu et al.   TOXICOLOGICAL SCIENCES

Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

(2009) Michael J. Knauer et al.   CIRCULATION RESEARCH

Species-Specific Differences in the Expression of the HNF1A, HNF1B and HNF4A Genes

(2009) Lorna W. Harries et al.   PLoS One