Article
Chemistry, Applied
Jiayue Guo, Amy Ellis, Yanqi Zhang, Lingyan Kong, Libo Tan
Summary: This study investigated the potential of starch-ascorbyl palmitate (AP) inclusion complexes (ICs) as a new type of slowly digested carbohydrate (RS5) for the prevention of type 2 diabetes. The ICs produced using the annealing followed by acid hydrolysis (ANN-ACH) method showed a more favorable digestion pattern and lower glycemic response in vitro and in vivo compared to the ICs produced by the dimethyl sulfoxide (DMSO) method. The ANN-ACH V6h-AP IC exhibited the lowest estimated glycemic index (GI) and glycemic response among all tested samples, suggesting its great potential as a new RS5.
CARBOHYDRATE POLYMERS
(2023)
Article
Food Science & Technology
Masatsugu Tamura, Hiroki Tsujii, Takahiro Saito, Yoshimasa Sasahara
Summary: The study investigated the relationship between starch digestibility and physicochemical properties of aged rice grains. It found that aged polished rice had higher levels of degradation compared to fresh rice, which correlated with the starch digestibility of the cooked grains.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Nutrition & Dietetics
Agnes Demangeat, Hugo Hornero-Ramirez, Alexandra Meynier, Philippe Sanoner, Fiona S. Atkinson, Julie-Anne Nazare, Sophie Vinoy
Summary: Dietary polyphenols, starch digestibility, and dietary fibers may play a role in modulating high glycemic response. This study formulated cereal products with high contents of these compounds and found that they have a low glycemic index and insulin index.
Article
Nutrition & Dietetics
Joanna Nadia, Alexander G. Olenskyj, Natascha Stroebinger, Suzanne M. Hodgkinson, Talia G. Estevez, Parthasarathi Subramanian, Harjinder Singh, R. Paul Singh, Gail M. Bornhorst
Summary: This study investigated how the physical structure of starch-rich foods affects small intestinal digestion and glycemic response in growing pigs. The results showed that food structure influenced the pigs' glycemic response and starch digestion kinetics.
JOURNAL OF NUTRITION
(2023)
Review
Food Science & Technology
Konstantinos Korompokis, Kristin Verbeke, Jan A. Delcour
Summary: This article focuses on the molecular structure of starch and its impact on digestibility and human health, discusses how to reduce the digestibility of starch through specific enzymes, and introduces relevant research and food applications.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Review
Food Science & Technology
Joanna Nadia, John Bronlund, Rajinder Paul Singh, Harjinder Singh, Gail M. Bornhorst
Summary: This review discusses the physical breakdown of starch-based foods in the mouth and stomach, the quantification of these breakdown processes, and their links to physiological outcomes, such as gastric emptying and glycemic response. It emphasizes that the physical breakdown prior to small intestinal digestion, especially during gastric digestion, should not be neglected in understanding the digestion of solid starch-based foods.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Article
Biochemistry & Molecular Biology
Babatunde Olawoye, Oladapo Fisoye Fagbohun, Oyekemi Olabisi Popoola, Saka Olasunkami Gbadamosi, Charles Taiwo Akanbi
Summary: In this study, cardaba banana starch was modified using various methods and the properties of both the modified and native starch were evaluated. The results showed that modification significantly influenced the properties of the starch and improved its suitability for food processing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Putlih Adzra Pautong, Joanne Jerenice Anonuevo, Maria Krishna de Guzman, Rodolfo Sumayao, Christiani Jeyakumar Henry, Nese Sreenivasulu
Summary: This study found that the fine structure components of starch and simulated digestion parameters can be used to predict the glycemic index (GI) of rice. The measurement of amylose, amylopectin, and resistant starch showed high correlation with GI. The extent of starch hydrolysis and the corresponding area under the digestion curve were found to be even more strongly correlated with GI, even within shorter digestion periods.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Hui Si Audrey Koh, Jin Er Leonard Chong, Jun Lu, Weibiao Zhou
Summary: This study found that adding fucoidan to bread can lower the glycemic index of the bread, and fucoidan is retained in the bread after baking. Although the in vitro bioavailability of fucoidan is low, it has high in vitro bioaccessibility, suggesting potential for absorption through other modes.
Review
Nutrition & Dietetics
Yeming Bai, Robert G. Gilbert
Summary: Obesity and type II diabetes are closely related to rapid starch digestion. Pectins, as plant polysaccharides, have diverse effects on starch digestion and can influence it through multiple mechanisms simultaneously, such as increasing digesta viscosity, inhibiting amylase activity, and regulating in vivo physiological responses.
Article
Chemistry, Applied
Hai-Teng Li, Zaifen Li, Glen P. Fox, Michael J. Gidley, Sushil Dhital
Summary: The study revealed that the increased protein content in native HAW flour and thermal stability of starch in HAW noodles lead to higher food integrity and consequently enhance the resistance against alpha-amylase digestion. Overall, the diversity of starch-protein interactions in wheat-based food products underlies the nutritional value of natural whole foods.
Article
Nutrition & Dietetics
Gautier Cesbron-Lavau, Aurelie Goux, Fiona Atkinson, Alexandra Meynier, Sophie Vinoy
Summary: This study evaluated the impact of different processing technologies on the starch digestibility profile of cereal-based foods, using advanced imaging techniques and in vivo evaluation methods. Rotary molding technology preserved starch in its intact form, resulting in the highest amount of slowly digestible starch and a lower glycemic and insulinemic response. The disruption of starch structure by the other processing technologies led to lower levels of slowly digestible starch.
Review
Chemistry, Applied
Xueer Yi, Cheng Li
Summary: The review evaluates the main factors affecting the resistant starch content of cooked white rice, aiming to assist the food industry in developing strategies to increase the resistant starch content.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Applied
Josephine Yee, Laura Roman, Joana Pico, Andres Aguirre-Cruz, Luis Arturo Bello-Perez, Eric Bertoft, Mario M. Martinez
Summary: This study analyzed the starch from six Musa cultivars and found significant differences in starch structure among them, including differences in amylose ratio, amylose branching degree, and the average length of long amylose unit chains. The cultivar Manzano, in particular, showed a dramatically lower extension of in vitro starch digestion compared to other cultivars.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
Yudy Duarte-Correa, Oscar Vega-Castro, Nataly Lopez-Baron, Jaspreet Singh
Summary: This study investigated the effects of impregnating vitamin E, vitamin C, and calcium through vacuum impregnation on the physico-chemical properties of potato chips, resulting in reduced starch hydrolysis and a consequent decrease in estimated glycemic index (eGI).
Article
Food Science & Technology
Carolina Bravo, Jose L. Santos, Gabriel Castillo, Gabriela Olivares, Javier Parada
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2020)
Article
Biochemistry & Molecular Biology
Cristina Vergara, Maria Teresa Pino, Olga Zamora, Javier Parada, Ricardo Perez, Marco Uribe, Julio Kalazich
Article
Chemistry, Applied
Estefania Gonzalez, Ana Maria Gomez-Caravaca, Begona Gimenez, Ruben Cebrian, Mercedes Maqueda, Javier Parada, Antonio Martinez-Ferez, Antonio Segura-Carretero, Paz Robert
Article
Endocrinology & Metabolism
Rodrigo Fernandez-Verdejo, Mauricio Castro-Sepulveda, Juan Gutierrez-Pino, Lorena Malo-Vintimilla, Antonio Lopez-Fuenzalida, Pablo Olmos, Jose L. Santos, Jose E. Galgani
Article
Chemistry, Medicinal
Luz Veronica Pacheco, Javier Parada, Jose Ricardo Perez-Correa, Maria Salome Mariotti-Celis, Fernanda Erpel, Angara Zambrano, Mauricio Palacios
Review
Endocrinology & Metabolism
Jose L. Santos, Victor A. Cortes
Summary: Most known types of nonsyndromic monogenic obesity are caused by rare mutations in genes of the leptin-melanocortin pathway controlling appetite and adiposity, while congenital generalized lipodystrophy is the most extreme form of leanness in humans caused by recessive mutations in four genes. Both conditions result in altered eating behavior and metabolic abnormalities, but exogenous leptin or drug treatments can have beneficial effects.
Article
Chemistry, Applied
Sergio Benavides, Maria Salome Mariotti-Celis, Maria Jose Carolina Paredes, Javier A. Parada, Wendy V. Franco
Summary: The study found that the distribution of thyme essential oil inside the microspheres was heterogeneous, and the microspheres experienced agglomeration and loss of sphericity after the drying process. Under gastric conditions, the acidic pH limited the swelling of TEO-MS, while the slightly alkaline intestinal pH favored their swelling and release rate.
JOURNAL OF MICROENCAPSULATION
(2021)
Article
Nutrition & Dietetics
Jose L. Santos, Bernardo J. Krause, Luis Rodrigo Cataldo, Javier Vega, Francisca Salas-Perez, Paula Mennickent, Raul Gallegos, Fermin I. Milagro, Pedro Prieto-Hontoria, J. Ignacio Riezu-Boj, Carolina Bravo, Albert Salas-Huetos, Ana Arpon, Jose E. Galgani, J. Alfredo Martinez
Review
Nutrition & Dietetics
Gigliola Alberti, Juan Cristobal Gana, Jose L. Santos
Article
Pediatrics
Victoria L. Buchanan, Yujie Wang, Estela Blanco, Mariaelisa Graff, Cecilia Albala, Raquel Burrows, Jose L. Santos, Barbara Angel, Betsy Lozoff, Venkata Saroja Voruganti, Xiuqing Guo, Kent D. Taylor, Yii-Der Ida Chen, Jie Yao, Jingyi Tan, Carolina Downie, Heather M. Highland, Anne E. Justice, Sheila Gahagan, Kari E. North
Summary: A novel variant in the CSMD1 gene was found to be associated with fasting insulin levels in Hispanic/Latino adolescents. Including diverse ancestral populations and adolescent participants in genetic studies can help uncover new risk loci and enhance our understanding of disease etiology.
Article
Biochemistry & Molecular Biology
Nils Leander Huaman-Castilla, David Campos, Diego Garcia-Rios, Javier Parada, Maximiliano Martinez-Cifuentes, Maria Salome Mariotti-Celis, Jose Ricardo Perez-Correa
Summary: The study revealed that grape pomace polyphenols can inhibit enzymes related to Type 2 Diabetes Mellitus, showing good antioxidant capacity and inhibitory effects on alpha-amylase and alpha-glucosidase. Higher temperatures during hot pressurized liquid extraction (HPLE) of Carmenere pomace resulted in increased polyphenol content and antioxidant capacity, while decreasing the inhibitory concentration.
Article
Biochemistry & Molecular Biology
Fernanda Erpel, Maria Salome Mariotti-Celis, Javier Parada, Franco Pedreschi, Jose Ricardo Perez-Correa
Summary: Brown seaweed phlorotannins have shown potential health benefits, with extracts from different anatomical parts of seaweed exhibiting varying polyphenol content and antioxidant capacity. Durvillaea incurvata seaweed from Niebla in central Chile showed the strongest alpha-glucosidase inhibitory activity. However, potentially hazardous cadmium levels and substantial mannitol concentrations were found in most seaweed samples and extracts, suggesting further purification steps may be necessary.
Article
Endocrinology & Metabolism
Jose Patricio Miranda, Maria Cecilia Lardone, Fernando Rodriguez, Gordon B. Cutler, Jose Luis Santos, Camila Corvalan, Ana Pereira, Veronica Mericq
Summary: The study identified one variant significantly associated with DHEAS concentrations at the genome-wide level, as well as several variants with suggestive associations that may be involved in the genetic regulation of adrenarche.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Cardiac & Cardiovascular Systems
Daeeun Kim, Annie Green Howard, Estela Blanco, Raquel Burrows, Paulina Correa-Burrows, Aylin Memili, Cecilia Albala, Jose L. Santos, Barbara Angel, Betsy Lozoff, Anne E. Justice, Penny Gordon-Larsen, Sheila Gahagan, Kari E. North
Summary: This study identified dynamic relationships between body fat and adipokines levels from late adolescence to young adulthood, particularly in a Hispanic/Latino population. These findings highlight the importance of this period of the life course in the development of obesity.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Cardiac & Cardiovascular Systems
Jose L. Santos, Miguel Ruiz-Canela, Cristina Razquin, Clary B. Clish, Marta Guasch-Ferre, Nancy Babio, Dolores Corella, Enrique Gomez-Gracia, Miquel Fiol, Ramon Estruch, Jose Lapetra, Montserrat Fito, Fernando Aros, Lluis Serra-Majem, Liming Liang, Maria Angeles Martinez, Estefania Toledo, Jordi Salas-Salvado, Frank B. Hu, Miguel A. Martinez-Gonzalez
Summary: This study aimed to evaluate the association between baseline and 1-year levels of plasma citric acid cycle (CAC) metabolites and cardiovascular disease (CVD) incidence, and their interaction with Mediterranean diet interventions.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
