The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial
出版年份 2017 全文链接
标题
The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial
作者
关键词
-
出版物
HEPATOLOGY
Volume 67, Issue 2, Pages 549-559
出版商
Wiley
发表日期
2017-09-12
DOI
10.1002/hep.29514
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease
- (2017) Charlie C. Park et al. GASTROENTEROLOGY
- Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis
- (2017) Parambir S. Dulai et al. HEPATOLOGY
- Hepatic proton density fat fraction correlates with histologic measures of steatosis and is responsive to change in those measures in a multi-center nonalcoholic steatohepatitis clinical trial
- (2017) M.S. Middleton et al. JOURNAL OF HEPATOLOGY
- Longitudinal changes in liver stiffness by magnetic resonance elastography (MRE), liver fibrosis, and serum markers of fibrosis in a multi-center clinical trial in nonalcoholic steatohepatitis (NASH)
- (2017) R. Loomba et al. JOURNAL OF HEPATOLOGY
- Efficacy and safety of simtuzumab for the treatment of nonalcoholic steatohepatitis with bridging fibrosis or cirrhosis: results of two phase 2b, dose-ranging, randomized, placebo-controlled trials
- (2017) A. Sanyal et al. JOURNAL OF HEPATOLOGY
- Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates
- (2017) Pi-Xiao Wang et al. NATURE MEDICINE
- EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
- (2016) et al. DIABETOLOGIA
- Novel Pharmacotherapy Options for NASH
- (2016) Vlad Ratziu DIGESTIVE DISEASES AND SCIENCES
- Serum biomarkers for nonalcoholic fatty liver disease: Are we there yet?
- (2016) Ken Liu et al. HEPATOLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Reduction of Liver Steatosis and Fibrosis with an Ask1 Inhibitor in a Murine Model of Nash is Accompanied by Improvements in Cholesterol, Bile Acid and Lipid Metabolism
- (2016) G. Budas et al. JOURNAL OF HEPATOLOGY
- Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial
- (2016) Jeffrey Cui et al. JOURNAL OF HEPATOLOGY
- MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: Clinical trials to clinical practice
- (2016) Parambir S. Dulai et al. JOURNAL OF HEPATOLOGY
- The therapeutic landscape of non-alcoholic steatohepatitis
- (2016) Hugo Perazzo et al. LIVER INTERNATIONAL
- Hepatic steatosis and fibrosis: Non-invasive assessment
- (2016) Rustam N Karanjia et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
- (2015) Paul Angulo et al. GASTROENTEROLOGY
- Nonalcoholic fatty liver disease: Fibrosis portends a worse prognosis
- (2015) Dawn M. Torres et al. HEPATOLOGY
- Quantitative magnetic resonance imaging of hepatic steatosis: Validation inex vivohuman livers
- (2015) Peter Bannas et al. HEPATOLOGY
- Ezetimibe for the treatment of nonalcoholic steatohepatitis: Assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial)
- (2015) Rohit Loomba et al. HEPATOLOGY
- Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
- (2015) Mattias Ekstedt et al. HEPATOLOGY
- Current efforts and trends in the treatment of NASH
- (2015) Vlad Ratziu et al. JOURNAL OF HEPATOLOGY
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials
- (2013) Mazen Noureddin et al. HEPATOLOGY
- 1319 SIMTUZUMAB, AN ANTIFIBROTIC MONOCLONAL ANTIBODY AGAINST LYSYL OXIDASE-LIKE 2 (LOXL2) ENZYME, APPEARS SAFE AND WELL TOLERATED IN PATIENTS WITH LIVER DISEASE OF DIVERSE ETIOLOGY
- (2013) A.H. Talal et al. JOURNAL OF HEPATOLOGY
- Role of magnetic resonance elastography in compensated and decompensated liver disease
- (2013) Sumeet K. Asrani et al. JOURNAL OF HEPATOLOGY
- Magnetic resonance elastography of liver: Technique, analysis, and clinical applications
- (2013) Sudhakar K. Venkatesh et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- The global NAFLD epidemic
- (2013) Rohit Loomba et al. Nature Reviews Gastroenterology & Hepatology
- Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD
- (2012) Z. Permutt et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: A randomized controlled trial
- (2012) Thuy-Anh Le et al. HEPATOLOGY
- The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
- (2012) Naga Chalasani et al. HEPATOLOGY
- Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
- (2011) G. Vernon et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States
- (2011) Michael R. Charlton et al. GASTROENTEROLOGY
- Pathologic criteria for nonalcoholic steatohepatitis: Interprotocol agreement and ability to predict liver-related mortality
- (2011) Zobair M. Younossi et al. HEPATOLOGY
- Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy
- (2011) Scott B. Reeder et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
- (2009) Cecilia Söderberg et al. HEPATOLOGY
- Relationship of serum fibrosis markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C
- (2008) Robert J. Fontana et al. HEPATOLOGY
- Olmesartan Prevents Cardiovascular Injury and Hepatic Steatosis in Obesity and Diabetes, Accompanied by Apoptosis Signal Regulating Kinase-1 Inhibition
- (2008) Eiichiro Yamamoto et al. HYPERTENSION
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