Hepatic IFIT3 predicts interferon-α therapeutic response in patients of hepatocellular carcinoma

Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils

(2016) Yanfang Liu et al.   CANCER CELL

Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling

(2016) Andy J. Minn et al.   CELL

Clearing Persistent Extracellular Antigen of Hepatitis B Virus: An Immunomodulatory Strategy To Reverse Tolerance for an Effective Therapeutic Vaccination

(2016) Danming Zhu et al.   JOURNAL OF IMMUNOLOGY

Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

(2016) Xia Li et al.   NATURE IMMUNOLOGY

Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells

(2016) Tadaatsu Imaizumi et al.   NEUROSCIENCE RESEARCH

Personalized Clinical Trials in Hepatocellular Carcinoma Based on Biomarker Selection

(2016) Bingnan Zhang et al.   Liver Cancer

Immunotherapy in hepatocellular carcinoma: Primed to make a difference?

(2015) James J. Harding et al.   CANCER

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

(2015) Dongjun Peng et al.   NATURE

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

Interferons and the Immunogenic Effects of Cancer Therapy

(2015) Andy J. Minn   TRENDS IN IMMUNOLOGY

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

(2015) Benjamin Ruf et al.   Molecular Therapy-Oncolytics

Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular “pseudoinflammation” contributing to an aggressive phenotype

(2015) Hanno Niess et al.   Oncotarget

Targeting the Tumor Microenvironment with Interferon-β Bridges Innate and Adaptive Immune Responses

(2014) Xuanming Yang et al.   CANCER CELL

Super-infection withStaphylococcus aureusinhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization

(2014) Kathrin Warnking et al.   CELLULAR MICROBIOLOGY

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

(2014) Liufu Deng et al.   IMMUNITY

Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

(2013) Jin Hou et al.   CANCER CELL

Sunitinib Versus Sorafenib in Advanced Hepatocellular Cancer: Results of a Randomized Phase III Trial

(2013) Ann-Lii Cheng et al.   JOURNAL OF CLINICAL ONCOLOGY

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

(2013) Yazan M. Abbas et al.   NATURE

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

(2011) Jin Hou et al.   CANCER CELL

IFN-Induced TPR Protein IFIT3 Potentiates Antiviral Signaling by Bridging MAVS and TBK1

(2011) X.-Y. Liu et al.   JOURNAL OF IMMUNOLOGY

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Targeted delivery of interferon-alpha via fusion to anti-CD20 results in potent antitumor activity against B-cell lymphoma

(2010) C. Xuan et al.   BLOOD

Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): A meta-regression approach

(2010) Ying-Chun Shen et al.   JOURNAL OF HEPATOLOGY

Systematic review and meta-analysis of interferon after curative treatment of hepatocellular carcinoma in patients with viral hepatitis

(2009) S. Breitenstein et al.   BRITISH JOURNAL OF SURGERY

IFN- -Induced Apoptosis in Hepatocellular Carcinoma Involves Promyelocytic Leukemia Protein and TRAIL Independently of p53

(2009) K. Herzer et al.   CANCER RESEARCH

MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer

(2009) Junfang Ji et al.   NEW ENGLAND JOURNAL OF MEDICINE

Respiratory Syncytial Virus Proteins Modulate Suppressors of Cytokine Signaling 1 and 3 and the Type I Interferon Response to Infection by a Toll-Like Receptor Pathway

(2009) Christine M. Oshansky et al.   VIRAL IMMUNOLOGY

Cancer Immunology

(2008) Olivera J. Finn   NEW ENGLAND JOURNAL OF MEDICINE