Article
Cardiac & Cardiovascular Systems
Takeru Nabeta, Shunsuke Ishii, Yuki Ikeda, Kenji Maemura, Takumi Oki, Mayu Yazaki, Teppei Fujita, Takashi Naruke, Takayuki Inomata, Junya Ako
Summary: A study on patients with recent-onset DCM found that 28% of patients experienced re-worsening of LVEF after initial improvement. High LGE burden, elevated B-type natriuretic peptide levels, and lower LVEF at initial LVEF recovery were independent predictors of re-worsening of LVEF in DCM patients.
Article
Cardiac & Cardiovascular Systems
Anne G. Raafs, Jacqueline L. Vos, Michiel T. H. M. Henkens, Bram O. Slurink, Job A. J. Verdonschot, Daan Bossers, Kit Roes, Suzanne Gerretsen, Christian Knackstedt, Mark R. Hazebroek, Robin Nijveldt, Stephane R. B. Heymans
Summary: This study evaluated the prognostic value of left atrial strain measured by cardiac magnetic resonance imaging in patients with dilated cardiomyopathy. The study found that left atrial conduit strain is a strong and independent predictor of prognosis in dilated cardiomyopathy, superior to left ventricular global longitudinal strain, left ventricular ejection fraction, and left atrial volume index. Including left atrial conduit strain in the management of dilated cardiomyopathy patients should be considered to improve risk stratification.
JACC-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Eun Kyoung Kim, Ga Yeon Lee, Shin Yi Jang, Sung-A Chang, Sung Mok Kim, Sung-Ji Park, Jin-Oh Choi, Seung Woo Park, Yeon Hyeon Choe, Sang-Chol Lee, Jae K. Oh
Summary: Cardiac magnetic resonance imaging can be used to predict long-term adverse cardiac outcomes in patients with non-ischemic cardiomyopathy, with an extent of late gadolinium enhancement exceeding 12.0 %LV indicating a higher risk of major adverse cardiac events.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sorin Giusca, Henning Steen, Moritz Montenbruck, Amit R. Patel, Burkert Pieske, Jennifer Erley, Sebastian Kelle, Grigorios Korosoglou
Summary: The study found that SENC myocardial strain is highly sensitive and specific for differentiating between athletes and HCM, athletes and HHD, and combining strain with LGE data is useful for distinguishing between HHD and HCM, HCM and cardiac amyloidosis.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Su Jin Lim, Hyun Jung Koo, Min Soo Cho, Gi-Byoung Nam, Joon-Won Kang, Dong Hyun Yang
Summary: This study found that LGE of the LV papillary muscles or ventricular wall in patients with mitral regurgitation is associated with high systolic blood pressure and ventricular arrhythmia, and should not be overlooked on CMR.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Daniele Muser, Gaetano Nucifora, Maurizio Pieroni, Simon A. Castro, Ruben Casado Arroyo, Shingo Maeda, Daniel A. Benhayon, Ioan Liuba, Mouhannad Sadek, Silvia Magnani, Andres Enriquez, Jackson J. Liang, Biagio Sassone, Benoit Desjardins, Sanjay Dixit, Rajat Deo, Fermin C. Garcia, David J. Callans, David S. Frankel, Joseph B. Selvanayagam, Francis E. Marchlinsk, Pasquale Santangeli
Summary: The study showed that in patients with apparently idiopathic nonsustained ventricular arrhythmias, a specific phenotype of LV scar characterized by a ringlike pattern is associated with malignant arrhythmic events and higher prognostic risk.
Article
Medicine, General & Internal
Chen Zhang, Hongbo Zhang, Lei Zhao, Zhipeng Wei, Yongqiang Lai, Xiaohai Ma
Summary: This study found differential expression of miRNAs in myocardial tissues of patients with hypertrophic cardiomyopathy (HCM). Some miRNAs were found to be correlated with left ventricular mass index and late gadolinium enhancement quantification. These myocardial miRNA levels could be potential biomarkers for LV hypertrophy, fibrosis, and remodeling.
Article
Medicine, General & Internal
Wei Huang, Ran Sun, Wenbin Liu, Rong Xu, Ziqi Zhou, Wei Bai, Ruilai Hou, Huayan Xu, Yingkun Guo, Li Yu, Lu Ye
Summary: In this study, the clinical and cardiovascular magnetic resonance data of 75 patients with left ventricular noncompaction were retrospectively analyzed. The results showed a correlation between late gadolinium enhancement types and major adverse cardiovascular events. A specific ring-like pattern and involvement of the free wall or mid-wall were associated with an increased risk of adverse cardiovascular events. The extent of late gadolinium enhancement greater than 7.5% and the presence of ring-like, multiple segments, and free-wall enhancement were significantly associated with major adverse cardiovascular events.
Article
Cardiac & Cardiovascular Systems
Xian Hou, Xing Xiong, Xia Li, Jianhua Bi, Gaofeng Xu, Yining Wang, Shu Jiang
Summary: This study retrospectively analyzed CMR images of 93 HCMpEF patients and 96 controls, finding significantly lower left ventricular mechanical parameters (GLS, GCS, GRS, and MCF) in the HCM group compared to controls. GLS and MCF independently predicted LGE, even in LGE-negative HCM patients. GLS and MCF may be ideal predictors for LGE.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Shingo Ota, Makoto Orii, Tsuyoshi Nishiguchi, Mao Yokoyama, Ryoko Matsushita, Kazushi Takemoto, Takashi Tanimoto, Kumiko Hirata, Takeshi Hozumi, Takashi Akasaka
Summary: This study indicates that patients with multiple LGE lesions in non-ischemic cardiomyopathy have a higher risk of cardiac events and poorer left ventricular reverse remodeling. The LGE pattern may be useful for improved risk stratification in patients with NICM.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Riccardo Cau, Giuseppe Muscogiuri, Francesco Pisu, Lorenzo Mannelli, Sandro Sironi, Jasjit S. Suri, Gianluca Pontone, Luca Saba
Summary: Left atrial function abnormalities in acute myocarditis patients are significantly associated with the location of left ventricle late gadolinium enhancement, but not with the extent of enhancement.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Amy C. O'Brien, Roisin MacDermott, Stephen Keane, David T. Ryan, Niall McVeigh, Rory Durand, Maria Ferre, David J. Murphy, Polakit Teekakirikul, David Keane, Ken McDonald, Mark Ledwidge, Jonathan D. Dodd
Summary: This study evaluated a manual method of measuring cardiac MRI e' as a measure of diastolic dysfunction in patients with hypertrophic cardiomyopathy. The results showed that cardiac MRI e' correlated with LGE and other feature tracking measures of diastolic function. It was also found to be an independent predictor of LGE >= 10% and diastolic dysfunction.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Alexandra Castelo, Silvia Aguiar Rosa, Antonio Fiarresga, Nuno Jalles, Vera Vaz Ferreira, Pedro Garcia Bras, Luisa Moura Branco, Mario Oliveira, Rui Cruz Ferreira
Summary: This study evaluated the relationship between atrial fibrillation and left ventricular late gadolinium enhancement in patients with hypertrophic cardiomyopathy. The results showed that late gadolinium enhancement in the mid inferior interventricular septum was an independent predictor for atrial fibrillation occurrence in these patients. Combining late gadolinium enhancement in the mid inferior interventricular septum and enlarged left atrium improved the prediction of atrial fibrillation.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Yang Ye, ZhongPing Ji, Wenli Zhou, Cailing Pu, Ya Li, Chengqin Zhou, Xiuhua Hu, Chao Chen, Yaxun Sun, Qi Huang, Wenjuan Zhang, Yu'e Qian, Hong Ren, Feidan Yu, Chenyang Jiang, Yankai Mao, Bei Wang, Joao B. Augusto, Dongwu Lai, Hongjie Hu, Guo-sheng Fu
Summary: The study found that scar entropy and %LGE are both independent risk indicators of ventricular arrhythmias in hypertrophic cardiomyopathy patients. A high scar entropy may indicate an arrhythmogenic scar, which could be valuable for clinical assessment of ventricular arrhythmias in these patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Cherry Kim, Chul Hwan Park, Do Yeon Kim, Jaehyung Cha, Bae Young Lee, Chan Ho Park, Eun-Ju Kang, Hyun Jung Koo, Kakuya Kitagawa, Min Jae Cha, Rungroj Krittayaphong, Sang Il Choi, Sanjaya Viswamitra, Sung Min Ko, Sung Mok Kim, Sung Ho Hwang, Nguyen Ngoc Trang, Whal Lee, Young Jin Kim, Jongmin Lee, Dong Hyun Yang
Summary: This study evaluated the effect of implementing the consensus statement on the reliability of cardiac MR with late gadolinium enhancement myocardial viability scoring. The results showed that the implementation of the consensus improved the interobserver agreement and reliability of the scoring.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Ahmed Ibrahim Ahmed, Yushui Han, Ahmed Soliman, Mouaz H. Al-Mallah
JOURNAL OF NUCLEAR CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Ahmed Ibrahim Ahmed, Jean Michel Saad, Moath Said Alfawara, Mouaz H. Al-Mallah
Review
Cardiac & Cardiovascular Systems
Mahmoud Al Rifai, Alka M. Kanaya, Namratha R. Kandula, Jaideep Patel, Mouaz H. Al-Mallah, Matthew Budoff, Miguel Cainzos-Achirica, Michael H. Criqui, Salim S. Virani
Summary: Individuals of South Asian ancestry have a higher risk of atherosclerotic cardiovascular disease. Coronary artery calcium volume and density can identify unique plaque characteristics in this population, providing important prognostic information. Cardiovascular risk factors are associated with CAC density and volume.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Subha Saeed, Jean Michel Saad, Ahmed Ibrahim Ahmed, Yushui Han, Mouaz H. Al-Mallah
Summary: Cardiac amyloidosis presents diagnostic challenges, but specialized amyloid-binding radiotracers may significantly improve diagnostic accuracy and treatment outcomes.
HEART FAILURE REVIEWS
(2022)
Review
Cardiac & Cardiovascular Systems
Jean Michel Saad, Ahmed Ibrahim Ahmed, Yushui Han, Subha Saeed, Payam Pournazari, Mouaz H. Al-Mallah
Summary: Cardiac amyloidosis is a form of restrictive cardiomyopathy that is often underdiagnosed and can rapidly progress to heart failure. Evaluating CA requires a multimodal approach, with the resurgence of technetium-labeled cardiac scintigraphy playing a key role in its diagnosis.
HEART FAILURE REVIEWS
(2022)
Article
Cardiac & Cardiovascular Systems
Alexander R. van Rosendael, Inge J. van den Hoogen, Fay Y. Lin, Umberto Gianni, Yao Lu, Daniele Andreini, Mouaz H. Al-Mallah, Filippo Cademartiri, Kavitha Chinnaiyan, Benjamin J. W. Chow, Edoardo Conte, Ricardo C. Cury, Gudrun Feuchtner, Pedro de Araujo Goncalves, Martin Hadamitzky, Yong-Jin Kim, Jonathon A. Leipsic, Erica Maffei, Hugo Marques, Fabian Plank, Gianluca Pontone, Gilbert L. Raff, Todd C. Villines, Sang-Eun Lee, Subhi J. Al'Aref, Lohendran Baskaran, Iksung Cho, Ibrahim Danad, Heidi Gransar, Matthew J. Budoff, Habib Samady, Renu Virmani, James K. Min, Jagat Narula, Daniel S. Berman, Hyuk-Jae Chang, Leslee J. Shaw, Jeroen J. Bax
Summary: The proportion of calcified plaque in patients with ACS increased significantly with older age, with lower calcification rates in patients younger than 50 years old. A high proportion of high risk markers such as low-attenuation plaque were observed in younger patients, while CACS was found to be >0 in a large percentage of patients older than 50 years.
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
(2022)
Article
Cardiac & Cardiovascular Systems
Yushui Han, Ahmed Ibrahim Ahmed, Chris Schwemmer, Myra Cocker, Talal S. Alnabelsi, Jean Michel Saad, Juan C. Ramirez Giraldo, Mouaz H. Al-Mallah
Summary: This study assessed the interoperator and intraoperator variability of coronary CT angiography-derived FFRCT using a machine learning-based postprocessing prototype. The results showed a high degree of reproducibility for FFRCT and greater variability in distal segments compared to proximal/mid segments.
Article
Cardiac & Cardiovascular Systems
Ahmed Ibrahim Ahmed, Jean Michel Saad, Yushui Han, Maan Malahfji, Mouaz H. Al-Mallah
Summary: This study aimed to determine the prognostic value of positron emission tomography (PET) derived left ventricular mass (LVM) in addition to clinical variables and myocardial flow reserve (MFR). The results showed that LVM was not independently associated with outcomes and had no incremental prognostic value over MFR and clinical variables.
JOURNAL OF NUCLEAR CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Maan Malahfji, Valentina Crudo, Ahmed Ibrahim Ahmed, Mujtaba Saeed, Jean Michel Saad, William A. Zoghbi, Mouaz H. Al-Mallah
JOURNAL OF NUCLEAR CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ahmed Ibrahim Ahmed, Mahmoud Al Rifai, Fares Alahdab, Jean Michel Saad, Yushui Han, Moath Said Alfawara, Faisal Nabi, John J. Mahmarian, Mouaz H. Al-Mallah
Summary: This study aimed to assess the prognostic value of myocardial flow reserve (MFR) using the latest generation of digital PET scanners in patients with suspected or known CAD. The results showed that impaired MFR was significantly associated with adverse events, and it significantly improved the predictive ability over traditional risk factors.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Mouaz H. Al-Mallah, Timothy M. Bateman, Kelley R. Branch, Andrew Crean, Eric L. Gingold, Randall C. Thompson, Sarah E. McKenney, Edward J. Miller, Venkatesh L. Murthy, Koen Nieman, Todd C. Villines, Michael V. Yester, Andrew J. Einstein, John J. Mahmarian
JOURNAL OF NUCLEAR CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Mahmoud Al Rifai, Moyses Szklo, Jaideep Patel, Michael J. Blaha, Christie M. Ballantyne, Vera Bittner, Pamela Morris, John W. McEvoy, Michael D. Shapiro, Mouaz H. Al-Mallah, Philip Greenland, Salim S. Virani
Summary: This observational study found no significant association between statin therapy and incident diabetes mellitus. The presence of baseline coronary artery calcium did not significantly affect the risk of incident diabetes.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Malek Nayfeh, Ahmed Ibrahim Ahmed, Fares Alahdab, Mahmoud Al Rifai, Mouaz Al-Mallah
Editorial Material
Cardiac & Cardiovascular Systems
Abdallah El Bizri, Mouaz H. AL-Mallah
Meeting Abstract
Cardiac & Cardiovascular Systems
Ibrahim Ahmed Ahmed, Jean Michel Saad, Yushui Han, Maan Malahfji, Mouaz H. Al-Mallah
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
