Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects

Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

(2014) Dao-Fu Dai et al.   AGING CELL

Autophagy is required for extension of yeast chronological life span by rapamycin

(2014) Ashley L. Alvers et al.   Autophagy

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver

(2013) Wilson C. Fok et al.   AGING CELL

Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

(2013) Yimin Fang et al.   Cell Metabolism

Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice

(2013) Joshua C. Drake et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Nutrient Signaling in Protein Homeostasis: An Increase in Quantity at the Expense of Quality

(2013) C. S. Conn et al.   Science Signaling

Rapamycin slows aging in mice

(2012) John E. Wilkinson et al.   AGING CELL

Calorie restriction increases cerebral mitochondrial respiratory capacity in a NO•-mediated mechanism: Impact on neuronal survival

(2012) Fernanda M. Cerqueira et al.   FREE RADICAL BIOLOGY AND MEDICINE

Calorie Restriction Does Not Increase Short-term or Long-term Protein Synthesis

(2012) B. F. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Topograph, a Software Platform for Precursor Enrichment Corrected Global Protein Turnover Measurements

(2012) Edward J. Hsieh et al.   MOLECULAR & CELLULAR PROTEOMICS

Metabolic Labeling Reveals Proteome Dynamics of Mouse Mitochondria

(2012) Tae-Young Kim et al.   MOLECULAR & CELLULAR PROTEOMICS

The Effect of Long Term Calorie Restriction onin VivoHepatic Proteostatis: A Novel Combination of Dynamic and Quantitative Proteomics

(2012) John C. Price et al.   MOLECULAR & CELLULAR PROTEOMICS

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

Eukaryotic elongation factor-2 (eEF2): its regulation and peptide chain elongation

(2011) Gautam Kaul et al.   CELL BIOCHEMISTRY AND FUNCTION

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Analysis of proteome dynamics in the mouse brain

(2010) J. C. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TOR pathway comes of age

(2009) Monique N. Stanfel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Modulation of oxidative phosphorylation machinery signifies a prime mode of anti-ageing mechanism of calorie restriction in male rat liver mitochondria

(2009) Diksha Dani et al.   BIOGERONTOLOGY

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Direct control of mitochondrial function by mTOR

(2009) Arvind Ramanathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic characterization of the murine mitochondrial proteome using functionally validated cardiac mitochondria

(2008) Jun Zhang et al.   PROTEOMICS