Downregulation of spinal astrocytic connexin43 leads to upregulation of interleukin-6 and cyclooxygenase-2 and mechanical hypersensitivity in mice

Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia

(2016) Justin S. Ko et al.   BRAIN BEHAVIOR AND IMMUNITY

CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5

(2016) Bao-Chun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Lycopene ameliorates neuropathic pain by upregulating spinal astrocytic connexin 43 expression

(2016) Fang Fang Zhang et al.   LIFE SCIENCES

Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice

(2016) Norimitsu Morioka et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The role of connexin43–Src interaction in astrocytomas: A molecular puzzle

(2016) A. Tabernero et al.   NEUROSCIENCE

Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats

(2016) Klaudia Kwiatkowski et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Proinflammatory cytokines downregulate connexin 43-gap junctions via the ubiquitin-proteasome system in rat spinal astrocytes

(2015) Fang Fang Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tumor necrosis factor-mediated downregulation of spinal astrocytic connexin43 leads to increased glutamatergic neurotransmission and neuropathic pain in mice

(2015) Norimitsu Morioka et al.   BRAIN BEHAVIOR AND IMMUNITY

Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice

(2014) Gang Chen et al.   BRAIN

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

Downregulation of connexin36 in mouse spinal dorsal horn neurons leads to mechanical allodynia

(2014) Yoki Nakamura et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Antinociceptive Effect of Tetrandrine on LPS-Induced Hyperalgesia via the Inhibition of IKKβ Phosphorylation and the COX-2/PGE2 Pathway in Mice

(2014) Hengguang Zhao et al.   PLoS One

Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells

(2014) F Rinaldi et al.   Cell Death & Disease

Activation of RISK and SAFE pathways is not involved in the effects of Cx43 deficiency on tolerance to ischemia–reperfusion injury and preconditioning protection

(2013) Jose A. Sánchez et al.   BASIC RESEARCH IN CARDIOLOGY

Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain

(2013) Satoshi Imai et al.   BRAIN

GSK-3β Inhibition Attenuates LPS-Induced Death but Aggravates Radiation-Induced Death via Down-Regulation of IL-6

(2013) Bailong Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Importance of glial activation in neuropathic pain

(2013) Joanna Mika et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Astrocytes—Multitaskers in chronic pain

(2013) Rikke Rie Hansen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glycogen synthase kinase 3 beta regulates glial glutamate transporter protein expression in the spinal dorsal horn in rats with neuropathic pain

(2013) Han-Rong Weng et al.   EXPERIMENTAL NEUROLOGY

A β1/2 Adrenergic Receptor-Sensitive Intracellular Signaling Pathway Modulates CCL2 Production in Cultured Spinal Astrocytes

(2013) Norimitsu Morioka et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Spinal astrocytes stimulated by tumor necrosis factor-α and/or interferon-γ attenuate connexin 43-gap junction via c-jun terminal kinase activity

(2013) Fang Fang Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Spinal Astrocyte Gap Junctions Contribute to Oxaliplatin-Induced Mechanical Hypersensitivity

(2013) Seo-Yeon Yoon et al.   JOURNAL OF PAIN

The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes

(2013) Rafael C. Dutra et al.   NEUROBIOLOGY OF DISEASE

Inhibition of glycogen synthase kinase-3β by lithium chloride suppresses 6-hydroxydopamine-induced inflammatory response in primary cultured astrocytes

(2013) Hong-Mei Wang et al.   NEUROCHEMISTRY INTERNATIONAL

The activation of P2Y6 receptor in cultured spinal microglia induces the production of CCL2 through the MAP kinases-NF-κB pathway

(2013) Norimitsu Morioka et al.   NEUROPHARMACOLOGY

Inhibition of glycogen synthase kinase 3beta activity with lithium prevents and attenuates paclitaxel-induced neuropathic pain

(2013) M. Gao et al.   NEUROSCIENCE

Primary cultures of rat cortical microglia treated with nicotine increases in the expression of excitatory amino acid transporter 1 (GLAST) via the activation of the α7 nicotinic acetylcholine receptor

(2013) N. Morioka et al.   NEUROSCIENCE

Inhibition of IL-6 signaling: A novel therapeutic approach to treating spinal cord injury pain

(2013) Jutatip Guptarak et al.   PAIN

Carbenoxolone Enhances TRAIL-Induced Apoptosis Through the Upregulation of Death Receptor 5 and Inhibition of Gap Junction Intercellular Communication in Human Glioma

(2013) Yulyana Yulyana et al.   STEM CELLS AND DEVELOPMENT

Role of connexin-43 in protective PI3K-Akt-GSK-3β signaling in cardiomyocytes

(2012) Satoko Ishikawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid

(2012) Joaquim Duran-Vilaregut et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glycogen synthase kinase-3 beta inhibitor suppresses Porphyromonas gingivalis lipopolysaccharide-induced CD40 expression by inhibiting nuclear factor-kappa B activation in mouse osteoblasts

(2012) Liu Die et al.   MOLECULAR IMMUNOLOGY

Gap junctional channels are parts of multiprotein complexes

(2011) Jean-Claude Hervé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

(2011) Makoto Tsuda et al.   BRAIN

Gap junctions mediate intercellular spread of sodium between hippocampal astrocytes in situ

(2011) Julia Langer et al.   GLIA

Ifenprodil restores GDNF-evoked Ca2+ signalling and Na+/K+-ATPase expression in inflammation-pretreated astrocytes

(2011) Christopher Lundborg et al.   JOURNAL OF NEUROCHEMISTRY

Spinal Astrocytes as Therapeutic Targets for Pathological Pain

(2010) Takayuki Nakagawa et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain

(2009) Y.-J. Gao et al.   JOURNAL OF NEUROSCIENCE

Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS

(2009) Ana G. Barbeito et al.   NEUROBIOLOGY OF DISEASE

Connexin43 is involved in the effect of endothelin-1 on astrocyte proliferation and glucose uptake

(2008) Sandra Herrero-González et al.   GLIA

Evidence for a Role of Connexin 43 in Trigeminal Pain Using RNA Interference In Vivo

(2008) Peter T. Ohara et al.   JOURNAL OF NEUROPHYSIOLOGY

Modulation of astrocyte P2Y1receptors by the carboxyl terminal domain of the gap junction protein Cx43

(2007) Eliana Scemes   GLIA