Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression

The contribution of neutrophils to CNS autoimmunity

(2018) Emily R. Pierson et al.   CLINICAL IMMUNOLOGY

Can we predict benign multiple sclerosis? Results of a 20-year long-term follow-up study

(2017) Arianna Sartori et al.   JOURNAL OF NEUROLOGY

IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination

(2017) Julian Zimmermann et al.   MOLECULAR NEUROBIOLOGY

Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

(2017) Stefan A. Berghoff et al.   Nature Communications

Acute axonal damage in three different murine models of multiple sclerosis: A comparative approach

(2016) Katharina Marie Höflich et al.   BRAIN RESEARCH

Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model

(2016) Debbie Le Blon et al.   Journal of Neuroinflammation

Neurodegeneration Triggers Peripheral Immune Cell Recruitment into the Forebrain

(2016) M. Scheld et al.   JOURNAL OF NEUROSCIENCE

Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury

(2016) Dearbhaile Dooley et al.   Stem Cell Reports

Extensive acute axonal damage in pediatric multiple sclerosis lesions

(2015) Sabine Pfeifenbring et al.   ANNALS OF NEUROLOGY

Promotion of experimental autoimmune encephalomyelitis upon neutrophil granulocytes’ stimulation with formyl-methionyl-leucyl-phenylalanine (fMLP) peptide

(2015) Ahmet Kasim Kilic et al.   AUTOIMMUNITY

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

(2015) Tim Clarner et al.   JOURNAL OF IMMUNOLOGY

Preferential Recruitment of Neutrophils into the Cerebellum and Brainstem Contributes to the Atypical Experimental Autoimmune Encephalomyelitis Phenotype

(2015) Yudong Liu et al.   JOURNAL OF IMMUNOLOGY

Transfer of Myelin-Reactive Th17 Cells Impairs Endogenous Remyelination in the Central Nervous System of Cuprizone-Fed Mice

(2015) E. G. Baxi et al.   JOURNAL OF NEUROSCIENCE

Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica

(2015) Laura Hertwig et al.   Multiple Sclerosis Journal

Aggressive multiple sclerosis: proposed definition and treatment algorithm

(2015) Carolina A. Rush et al.   Nature Reviews Neurology

Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica

(2015) Laura Hertwig et al.   Multiple Sclerosis Journal

The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination

(2014) A Slowik et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases

(2014) Benoit Aubé et al.   JOURNAL OF IMMUNOLOGY

Conditional Ablation of Astroglial CCL2 Suppresses CNS Accumulation of M1 Macrophages and Preserves Axons in Mice with MOG Peptide EAE

(2014) M. Moreno et al.   JOURNAL OF NEUROSCIENCE

Chemokine (C-C Motif) Receptor 1 Is Required for Efficient Recruitment of Neutrophils during Respiratory Infection with Modified Vaccinia Virus Ankara

(2014) P. J. R. Price et al.   JOURNAL OF VIROLOGY

The most fulminant course of the Marburg variant of multiple sclerosis—autopsy findings

(2014) JC Nunes et al.   Multiple Sclerosis Journal

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Glial influence on the blood brain barrier

(2013) Jorge Ivan Alvarez et al.   GLIA

Neutrophils Amplify Autoimmune Central Nervous System Infiltrates by Maturing Local APCs

(2013) K. Steinbach et al.   JOURNAL OF IMMUNOLOGY

Neuroaxonal Regeneration is More Pronounced in Early Multiple Sclerosis than in Traumatic Brain Injury Lesions

(2012) Lucas Schirmer et al.   BRAIN PATHOLOGY

Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma

(2012) Susan Noell et al.   CELL AND TISSUE RESEARCH

Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

(2012) Tim Clarner et al.   GLIA

Differential Regulation of CD4+ T Cell Adhesion to Cerebral Microvascular Endothelium by the β-Chemokines CCL2 and CCL3

(2012) Kenneth Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease

(2012) Laura Codarri et al.   TRENDS IN IMMUNOLOGY

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI

(2011) Susann Boretius et al.   NEUROIMAGE

Extensive infiltration of neutrophils in the acute phase of experimental autoimmune encephalomyelitis in C57BL/6 mice

(2010) Fenglan Wu et al.   HISTOCHEMISTRY AND CELL BIOLOGY

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

(2010) LiPing Liu et al.   NATURE NEUROSCIENCE

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Cerebellar Cortical Demyelination in the Murine Cuprizone Model

(2009) Thomas Skripuletz et al.   BRAIN PATHOLOGY

Cuprizone Treatment Induces Distinct Demyelination, Astrocytosis, and Microglia Cell Invasion or Proliferation in the Mouse Cerebellum

(2009) Angela Groebe et al.   CEREBELLUM

Long-term follow-up of benign multiple sclerosis in Hordaland County, Western Norway

(2009) SB Glad et al.   Multiple Sclerosis Journal

17β-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice

(2008) Peter Acs et al.   GLIA

The Th17–ELR+CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

(2008) Thaddeus Carlson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MHC class II exacerbates demyelination in vivo independently of T cells

(2008) Meenaxi M. Hiremath et al.   JOURNAL OF NEUROIMMUNOLOGY

Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus

(2008) Akvile Norkute et al.   JOURNAL OF NEUROSCIENCE RESEARCH

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

(2008) Satoshi Serada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA