Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in Drosophila gene expression and development

Molecular mechanisms that distinguish TFIID housekeeping from regulatable SAGA promoters

(2016) Wim J de Jonge et al.   EMBO JOURNAL

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

(2015) Calley L. Hirsch et al.   GENES & DEVELOPMENT

Conformational Flexibility and Subunit Arrangement of the Modular Yeast Spt-Ada-Gcn5 Acetyltransferase Complex

(2015) Dheva Setiaputra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Usp22 deficiency impairs intestinal epithelial lineage specification in vivo

(2015) Robyn L. Kosinsky et al.   Oncotarget

dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster

(2015) Zoltan Pahi et al.   PLoS One

Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex

(2014) Y. Han et al.   EMBO JOURNAL

Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration

(2014) R. D. Mohan et al.   GENES & DEVELOPMENT

The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription

(2014) Jacques Bonnet et al.   GENES & DEVELOPMENT

Histone acetyltransferase Enok regulates oocyte polarization by promoting expression of the actin nucleation factorspire

(2014) Fu Huang et al.   GENES & DEVELOPMENT

DNA Binding by Sgf11 Protein Affects Histone H2B Deubiquitination by Spt-Ada-Gcn5-Acetyltransferase (SAGA)

(2014) Christian Koehler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional characterization and gene expression profiling of Drosophila melanogaster short dADA2b isoform-containing dSAGA complexes

(2013) Tibor Pankotai et al.   BMC GENOMICS

A global change in RNA polymerase II pausing during the Drosophila midblastula transition

(2013) Kai Chen et al.   eLife

Mammalian Alteration/Deficiency in Activation 3 (Ada3) Is Essential for Embryonic Development and Cell Cycle Progression

(2012) Shakur Mohibi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development

(2012) Zhenghong Lin et al.   MOLECULAR CELL

Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex

(2011) Dominique Helmlinger et al.   EMBO JOURNAL

Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation

(2011) V. M. Weake et al.   GENES & DEVELOPMENT

Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123

(2011) J. M. Schulze et al.   GENES & DEVELOPMENT

Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model

(2011) Yi Chun Chen et al.   HUMAN MOLECULAR GENETICS

SAGA and ATAC Histone Acetyl Transferase Complexes Regulate Distinct Sets of Genes and ATAC Defines a Class of p300-Independent Enhancers

(2011) Arnaud R. Krebs et al.   MOLECULAR CELL

Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes

(2011) K. K. Lee et al.   Molecular Systems Biology

Structural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase Module

(2010) Alwin Köhler et al.   CELL

The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes

(2009) N. Zsindely et al.   NUCLEIC ACIDS RESEARCH

Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes

(2009) Kenneth K Lee et al.   Epigenetics & Chromatin

SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system

(2008) Vikki M Weake et al.   EMBO JOURNAL

The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8

(2008) D. Helmlinger et al.   GENES & DEVELOPMENT

The Human SPT20-Containing SAGA Complex Plays a Direct Role in the Regulation of Endoplasmic Reticulum Stress-Induced Genes

(2008) Z. Nagy et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export

(2008) Alwin Köhler et al.   NATURE CELL BIOLOGY

Drosophila Stem Cells Share a Common Requirement for the Histone H2B Ubiquitin Protease Scrawny

(2008) M. Buszczak et al.   SCIENCE