Article
Cell Biology
Hilda Mardiana Pratiwi, Masahiro Hirasawa, Kohki Kato, Keijiro Munakata, Shogo Ueda, Yuuta Moriyama, Reiko Yu, Toru Kawanishi, Mikiko Tanaka
Summary: The development of the anterior and posterior paired appendages in vertebrates exhibits heterochrony, with the posterior ones emerging later than the anterior ones. In zebrafish, the pelvic fin buds appear during metamorphosis, while the pectoral fin buds arise during the embryonic stage. This study investigates how the fate of presumptive pelvic fin cells is maintained from the embryonic stage until metamorphosis, and identifies the role of pitx1 in this process.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Li-Yih Lin, Chieh-An Cheng, Sian-Tai Liu, Jiun-Lin Horng
Summary: This study reveals that ammonia exposure impairs ion regulation in zebrafish embryos by inducing oxidative stress, mitochondrial dysfunction, and cell death. The findings suggest that ammonia is toxic to aquatic animals and can lead to the death of embryos.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2024)
Article
Engineering, Environmental
Bin Huang, Yu-Qing Cui, Wen-Bo Guo, Liuyan Yang, Ai-Jun Miao
Summary: The study highlights the significant impact of NPs on the bioaccumulation of Cd in aquatic organisms, with the aggregation state of NPs further influencing the outcome of metal bioaccumulation.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Marine & Freshwater Biology
Phunsin Kantha, Sian-Tai Liu, Jiun-Lin Horng, Li-Yih Lin
Summary: This study found that nanoplastics can impair skin cells in zebrafish, including damaging the structure of keratinocytes, reducing the number and mitochondrial activity of ionocytes, and inducing oxidative stress in skin cells. Nanoplastics also reduced the expression of antioxidant genes and promoted the expression of apoptosis-related genes.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Chia-Hao Lin, Hung-Chi Chang, Sian-Tai Liu, Huei-Jyun Hu
Summary: Freshwater teleosts have defense mechanisms to maintain the homeostasis of body-fluid ion and acid-base balance. Vitamin D plays an important role in the regulation of Ca2+ uptake and acid secretion in these fish. The present study explored the effect of vitamin D on ionocyte proliferation and differentiation using zebrafish larvae as a model. The results showed that vitamin D treatment increased the number of ionocyte progenitors and mature ionocytes, suggesting a positive effect on ionocyte differentiation and stress adaptation in fish.
FRONTIERS IN MARINE SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Shuangshuang Zhao, Qikun Zhang, Mingyue Liu, Huapeng Zhou, Changle Ma, Pingping Wang
Summary: Plants adapt to high-salt environments by regulating ion balance, activating osmotic stress pathways, mediating plant hormone signaling, and adjusting cytoskeleton dynamics and cell wall composition in response to salt stress signals. Understanding these mechanisms is crucial for improving agricultural crop yields.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Jiun-Lin Horng, Chih-Ying Lee, Sian-Tai Liu, Giun-Yi Hung, Li-Yih Lin
Summary: This study reveals that AgNPs can have differential adverse effects on two types of ionocytes in zebrafish, which may pose a threat to fish survival.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Review
Endocrinology & Metabolism
Yutong Xing, Fan Xuan, Kaixi Wang, Huifeng Zhang
Summary: Aging is a biological process that leads to a progressive decline in physiological function due to interaction between the environment and the body. It can result in dysfunction of vital organ systems and the onset of age-related diseases that significantly impact quality of life. The endocrine system plays a role in coordinating cellular interactions, metabolism, growth, and aging through hormones and related functional factors. This paper explores the mechanisms of growth hormone, thyroid hormone, and estrogen in the aging process, offering insights into endocrine mechanisms associated with aging.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Genetics & Heredity
Yue Zhai, Xin Zhang, Cheng Zhao, Ruijing Geng, Kun Wu, Mingzhe Yuan, Nana Ai, Wei Ge
Summary: This study using zebrafish as a model revealed the critical role of bone morphogenetic protein 15 (BMP15) and inhibin in regulating folliculogenesis and sex determination. BMP15 deficiency led to follicle development arrest and sex reversal, which could be partially rescued by the loss of inhibin.
Review
Biochemistry & Molecular Biology
Tatiana O. Kolesnikova, Konstantin A. Demin, Fabiano Costa, Konstantin N. Zabegalov, Murilo S. de Abreu, Elena Gerasimova, Allan Kalueff
Summary: Channelopathies are systemic disorders associated with dysfunctional ion channels. The zebrafish has become a popular model organism for studying these disorders, but there are still challenges to overcome.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Food Science & Technology
Meifang Wu, Naying Zheng, Xiaoxiao Zhan, Jianzhang He, Min Xiao, Zhenghong Zuo, Chengyong He
Summary: This study demonstrates that Icariin may cause developmental toxicity by disrupting thyroid development and hormone synthesis, highlighting the importance of risk assessments in clinical practice.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
XiaoDong Jin, WenYe Liu, Jing Miao, ZhiPeng Tai, LingYa Li, PengPeng Guan, Jing-Xia Liu
Summary: The study shows that disrupted Cu2+ homeostasis can lead to developmental defects in zebrafish myogenesis, possibly through regulating gene promoter methylation and histone modification to affect signaling transduction pathways.
Article
Environmental Sciences
Liguo Qiu, Shuhui Wei, Yunsheng Wang, Rui Zhang, Shaoguo Ru, Xiaona Zhang
Summary: This study found that BPS affects the visual function of zebrafish larvae and stimulates the metabolism of all-trans-retinoic acid. By modulating the expression of CYP26A1 and TRO, it was found that CYP26A1 plays a crucial role in the oxidative metabolism of atRA and regeneration of retinoids in the visual cycle, and TRO mediates cyp26a1 expression in zebrafish eyes.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Hyunggyu Kim, Kyunghee Ji
Summary: This study investigated the effects of TMBPF on the endocrine system using zebrafish embryos and larvae. The results showed that TMBPF exposure led to reduced body weight, increased triiodothyronine levels, decreased growth hormone levels, and altered gene transcription associated with thyroid hormones and growth hormones.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Biochemistry & Molecular Biology
Somayyeh Heidary, Nagendra Awasthi, Nicole Page, Theo Allnutt, Rowena S. Lewis, Clifford Liongue, Alister C. Ward
Summary: This study aimed to generate a zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (GHISID1) by targeting the stat5.1 gene using CRISPR/Cas9. The zebrafish Stat5.1 mutants exhibited smaller size and increased adiposity, with dysregulation of growth and lipid metabolism genes. The mutants also showed impaired lymphopoiesis with reduced T cells throughout the lifespan, along with broader disruption of the lymphoid compartment in adulthood, including evidence of T cell activation.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2023)
Article
Endocrinology & Metabolism
Xiaomeng Li, Charles Brighton Ndandala, Qi Zhou, Chunyan Huang, Guangli Li, Huapu Chen
Summary: This study investigated the role of estrogen receptors (ERs) in vitellogenesis (Vtgs) regulation in pompano fish. The findings suggest that E2 may regulate the expression of different subtypes of vtg through ERs, displaying a compensatory expression effect on the regulation of ers and vtgs. This provides a theoretical basis for further research on reproductive endocrinology in pompano fish.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Norio Kansaku, Takeshi Ohkubo
Summary: Endocrine changes during bird reproduction, particularly the relationship between prolactin and incubation behavior, were investigated. The study monitored the physiological status and incubation behavior of Silkie hens over 1-2 years. The results showed that most mature hens exhibited incubation behavior multiple times, and there was a noticeable increase in nest occupancy 7-10 days before incubation onset. Protein analysis revealed that secreted prolactin during the reproductive cycle contains various isoforms, suggesting post-translational modifications like glycosylation and phosphorylation.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Minghui Li, Lina Sun, Linyan Zhou, Deshou Wang
Summary: This article summarizes the importance of the Nile tilapia as an excellent animal model for studying reproductive endocrinology in fish, with a focus on the crucial role of estrogen in female development.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Breanna N. Harris, Carolyn M. Bauer, James A. Carr, Caitlin R. Gabor, Jennifer L. Grindstaff, Caleigh Guoynes, Jennifer J. Heppner, Cris C. Ledon-Rettig, Patricia C. Lopes, Sharon E. Lynn, Carla B. Madelaire, Lorin A. Neuman-Lee, Maria G. Palacios, Paul Soto, Jennifer Terry
Summary: The COVID-19 pandemic had a significant impact on academics, particularly on those with minoritized identities or who were early career, caregivers, or had intersecting identities. The pandemic altered the impact factors of academia, including scholarly products, and affected the way individuals could respond. It is predicted that the pandemic will have long-term impacts on the population dynamics, composition, and landscape of the academic ecosystem. The number of journal submissions decreased, especially among women authors, and the pandemic heavily impacted women authors from Asia and the Middle East.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)