Article
Gastroenterology & Hepatology
Vineet S. Rolston, Jessica Kimmel, Violeta Popov, Brian P. Bosworth, David Hudesman, Lisa B. Malter, Simon Hong, Shannon Chang
Summary: The meta-analysis found that there was no significant difference in rates of serious or mild/moderate adverse events between Ustekinumab and placebo in randomized controlled trials.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Gregory B. Lim
Summary: Data from the TRAVERSE trial suggests that testosterone-replacement therapy in men with hypogonadism and a high risk of cardiovascular disease does not pose an increased risk of adverse cardiac events.
NATURE REVIEWS CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Patrick M. Wanner, Dirk U. Wulff, Mirjana Djurdjevic, Wolfgang Korte, Thomas W. Schnider, Miodrag Filipovic
Summary: This study found that targeting higher intraoperative mean arterial blood pressures (75 mm Hg) in cardiovascular risk patients undergoing major noncardiac surgery did not significantly reduce the incidence of postoperative major adverse cardiovascular events. Despite a shorter duration of hypotensive time during surgery, there were no significant differences in outcomes such as acute myocardial injury and 30-day MACE/AKI between the higher and lower blood pressure target groups.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Editorial Material
Gastroenterology & Hepatology
Adam S. Faye, Jordan E. Axelrad
Summary: This article is related to Moens et al papers.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Reeva C. Mincer, Renna Hazboun Zahr, Evelyn M. Chung, Bernard Kubak, Eric C. Sung
Summary: Preoperative dental intervention before cardiovascular surgery does not increase the risk of adverse events, as shown by this study. The research suggests that elimination of oral infection prior to CVS is safe in terms of morbidity and mortality.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Article
Surgery
Kiavash Koko, Jonathan T. Carter
Summary: A routine resting preoperative echocardiography did not significantly improve the cardiopulmonary risk stratification of patients undergoing bariatric surgery. High-risk patients, particularly those with a history of coronary artery disease and coronary revascularization, can be identified based on their medical history.
SURGERY FOR OBESITY AND RELATED DISEASES
(2021)
Article
Multidisciplinary Sciences
Shunsuke Tsuzuki, Shotaro Nakanishi, Mitsuyoshi Tamaki, Takuma Oshiro, Jun Miki, Hiroki Yamada, Tatsuya Shimomura, Takahiro Kimura, Nozomu Furuta, Seiichi Saito, Shin Egawa
Summary: A retrospective study of 233 CRPC patients found that reducing the initial dose of enzalutamide did not significantly decrease the incidence rate of AEs and resulted in poorer PSA response rate. There is currently no clear rationale for using a reduced initial dose of enzalutamide to reduce the incidence of AEs.
Article
Multidisciplinary Sciences
Shunsuke Tsuzuki, Shotaro Nakanishi, Mitsuyoshi Tamaki, Takuma Oshiro, Jun Miki, Hiroki Yamada, Tatsuya Shimomura, Takahiro Kimura, Nozomu Furuta, Seiichi Saito, Shin Egawa
Summary: The study found that initiating treatment with a reduced dose of enzalutamide in patients with CRPC did not significantly decrease the incidence rate of adverse events (AEs) and showed poorer PSA response rate. There is no clear rationale for treating with a reduced initial dose of enzalutamide to reduce the incidence of AEs.
Article
Medicine, General & Internal
Kosuke Mizutani, Toshiki Ito, Kiyoshi Takahara, Ryosuke Ando, Takuma Ishihara, Takahiro Yasui, Ryoichi Shiroki, Hideaki Miyake, Takuya Koie
Summary: In RCC patients treated with nivolumab, there is a correlation between the number of previous targeted therapies and immune-related adverse events (irAE). Close monitoring of patients is required regardless of the number of prior treatments.
Article
Medicine, General & Internal
Odeya Barayev, Chelsea E. Hawley, Helen Wellman, Hanna Gerlovin, Whitney Hsu, Julie M. Paik, Ernest I. Mandel, Christine K. Liu, Luc Djousse, J. Michael Gaziano, David R. Gagnon, Ariela R. Orkaby
Summary: This study evaluates the association of statin use with all-cause mortality and major adverse cardiovascular events (MACE) in US veterans with CKD stages 3 to 4. The results suggest that statin initiation is significantly associated with a lower risk of all-cause mortality but not MACE in older US veterans with CKD.
Article
Immunology
Maria Elena Flacco, Cecilia Acuti Martellucci, Graziella Soldato, Giuseppe Di Martino, Roberto Carota, Marco De Benedictis, Graziano Di Marco, Giustino Parruti, Rossano Di Luzio, Antonio Caponetti, Lamberto Manzoli
Summary: This cohort study examined the incidence of potentially vaccine-related serious adverse events (PVR-SAEs) in the entire population of an Italian Province based on COVID-19 vaccination status. The findings showed that vaccinated individuals did not have an increased risk of death or PVR-SAEs compared to the unvaccinated. These results were consistent across different demographics, vaccine types, and infection statuses. Further research is needed to assess the long-term safety of COVID-19 vaccines.
Article
Multidisciplinary Sciences
Clementine Seguigne, Michel Begue, Carl Meyer, Johann Mourier, Eric Clua
Summary: A criticism of provisioning ecotourism is that it alters the natural behavior and ecology of species. This study evaluated its impact on tiger sharks in French Polynesia and found that the sharks exhibited low site fidelity and there was no increase in fidelity over time. Furthermore, the number of tiger sharks sighted did not increase. Therefore, a strict code of conduct should be implemented during any future provisioning activities.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Andrea Picchianti Diamanti, Assunta Navarra, Gilda Cuzzi, Alessandra Aiello, Simonetta Salemi, Roberta Di Rosa, Chiara De Lorenzo, Daniele Vio, Giandomenico Sebastiani, Mario Ferraioli, Maurizio Benucci, Francesca Li Gobbi, Fabrizio Cantini, Vittoria Polidori, Maurizio Simmaco, Esmeralda Cialdi, Palma Scolieri, Vincenzo Bruzzese, Emanuele Nicastri, Raffaele D'Amelio, Bruno Lagana, Delia Goletti
Summary: This multicenter prospective study analyzed the safety of the BNT162b2 vaccine in rheumatoid arthritis patients. The vaccine showed good safety profile with low incidence of adverse events. Flares occurred in a small percentage of patients after vaccination. Influenza vaccination was inversely associated with adverse events after the second dose. Effectiveness of the vaccine against breakthrough infections decreased after the third dose, possibly due to Omicron variants. Overall, the study findings are important for understanding vaccine safety and effectiveness in autoimmune rheumatic diseases.
Article
Physics, Multidisciplinary
Lotte Mertens, Jasper van Wezel
Summary: The argument of environment-assisted invariance (envariance) is commonly used in quantum measurement models to justify their ability to produce accurate statistics, particularly linear models. However, recent research has shown that linear collapse models cannot reproduce Born's rule. In this study, we address this contradiction and identify an inconsistency in the assumptions underlying envariance-based arguments. By explicitly considering the construction of a measurement machine, we demonstrate that envariance does not guarantee that every measurement will follow Born's rule. Instead, it implies that a measurement machine can be constructed for every quantum state, which yields Born's rule when measuring that specific state. This resolution aligns with the recent finding that objective collapse models must be nonlinear.
Article
Endocrinology & Metabolism
Oksana Maksymchuk, Angela Shysh, Dmytro Stroy
Summary: Long-term treatment with omega-3 PUFAs does not increase the risk of CYP2E1-dependent oxidative stress and development of liver pathology but prevents some diabetic ultrastructural damage to hepatocytes.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Gastroenterology & Hepatology
M. Halland, K. V. Grooteman, T. H. Baron
DISEASES OF THE ESOPHAGUS
(2016)
Article
Surgery
Tomas DaVee, Shayan Irani, Cadman L. Leggett, Manuel Berzosa Corella, Karina V. Grooteman, Louis-Michel Wong Kee Song, Michael B. Wallace, Richard A. Kozarek, Todd H. Baron
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2016)
Article
Gastroenterology & Hepatology
Karina V. Grooteman, Erwin J. M. van Geenen, Joost P. H. Drenth
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2016)
Meeting Abstract
Gastroenterology & Hepatology
Karina Grooteman, Wietske Kievit, Alba Rocco, Grainne Holleran, Paulo Salgueiro, Thomas Aparicio, Giuseppe Scaglione, Raul Manzano, Denis Sautereau, Spyridon Michopoulos, Deirdre McNamara, Joost Drenth, Erwin van Geenen
Meeting Abstract
Gastroenterology & Hepatology
Karina Grooteman, Mijntje Matheeuwsen, Erwin van Geenen, Joost Drenth
Article
Multidisciplinary Sciences
Karina V. Grooteman, Mijntje Matheeuwsen, Erwin J. M. van Geenen, Joost P. H. Drenth
Article
Gastroenterology & Hepatology
K. V. Grooteman, E. J. M. van Geenen, W. Kievit, J. P. H. Drenth
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2017)
Article
Gastroenterology & Hepatology
Xavier J. N. M. Smeets, Iris Knoester, Karina Grooteman, Vikesh K. Singh, Peter A. Banks, Georgios Papachristou, Andres Duarte-Rojo, Guillermo Robles-Diaz, Wietske Kievit, Marc G. H. Besselink, Robert C. Verdonk, Hjalmar C. Van Santvoort, Joost P. H. Drenth, Michael Belias, Erwin J. M. Van Geenen
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2019)
Letter
Hematology
Steven Kroon, Repke J. Snijder, Johannes J. Mager, Martijn C. Post, Jacco Tenthof van Noorden, Erwin J. M. van Geenen, Joost P. H. Drenth, Karina V. Grooteman
AMERICAN JOURNAL OF HEMATOLOGY
(2019)
Review
Gastroenterology & Hepatology
K. V. Grooteman, G. Holleran, M. Matheeuwsen, E. J. M. van Geenen, D. McNamara, J. P. H. Drenth
DIGESTIVE DISEASES AND SCIENCES
(2019)
Review
Gastroenterology & Hepatology
Lia C. M. J. Goltstein, Karina Grooteman, Alba Rocco, Grainne Holleran, Santiago Frago, Paulo S. Salgueiro, Thomas Aparicio, Giuseppe Scaglione, Stefania Chetcuti Zammit, Raul Prados-Manzano, Robert Benamouzig, Gerardo Nardone, Deirdre McNamara, Mourad Benallaoua, Spyridon Michopoulos, Reena Sidhu, Wietske Kievit, Joost P. H. Drenth, Erwin J. M. van Geenen
Summary: In a meta-analysis of individual patient data, somatostatin analogues were found to significantly reduce the number of red blood cell transfusions in patients with gastrointestinal angiodysplasias, with a good response observed in the majority of patients. Patients with angiodysplasias located in the small bowel and colon showed better treatment responses, and octreotide therapy appeared to be more effective than lanreotide therapy.
LANCET GASTROENTEROLOGY & HEPATOLOGY
(2021)
Meeting Abstract
Gastroenterology & Hepatology
Liat Goltstein, Lucas H. Bernts, Karina V. Grooteman, Bob Scheffer, Robert Laheij, Lennard Gilissen, Ruud W. Schrauwen, Nynke C. Talstra, Abraham T. Zuur, Henri Braat, Muhammed Hadithi, Johannes T. Brouwer, Wouter B. Nagengast, Frank A. Oort, Jacco Tenthof van Noorden, Wietske Kievit, Erwin-Jan M. Van Geenen, Joost Drenth
Meeting Abstract
Gastroenterology & Hepatology
Lia Goltstein, Karina V. Grooteman, Alba Rocco, Grainne Holleran, Santiago Frago, Paulo Salgueiro, Thomas Aparicio, Giuseppe Scaglione, Stefania Chetcuti Zammit, Raul Manzano, Robert Benamouzig, Deirdre Monamara, Mourad Benallaoua, Spyridon Michopoulos, Reena Sidhu, Wietske Kievit, Joost Drenth, Erwin-Jan M. Van Geenen
Article
Medicine, General & Internal
M. S. Krijbolder, K. V. Grooteman, S. K. Bogers, D. J. de Jong
NETHERLANDS JOURNAL OF MEDICINE
(2018)