Article
Neurosciences
Yiheng Tu, Jin Cao, Seyhmus Guler, Thalia Chai-Zhang, Joan A. Camprodon, Mark Vangel, Randy L. Gollub, Darin D. Dougherty, Jian Kong
Summary: The study focused on assessing the modulatory effects of stimulating target brain regions on fMRI brain dynamics using repeated tDCS-fMRI sessions with healthy participants. Results indicated that enhancing neuronal excitability of certain brain regions significantly affected the occurrence rates and transitions of different CAPs, with these changes persisting over several days.
Article
Clinical Neurology
Qingqing Zhang, Tingting Chen, Shanshan Liu, Xinying Liu, Yifan Zhang, Fengqiong Yu, Gong-Jun Ji, Xiaoming Li, Chunyan Zhu
Summary: This study investigated the effects of anodal high-definition transcranial direct current stimulation (HD-tDCS) on the right ventrolateral prefrontal cortex (rVLPFC) and the right dorsolateral prefrontal cortex (rDLPFC) on implicit emotion regulation (ER). The results showed that stimulation of both the rVLPFC and the rDLPFC could significantly reduce the affective responses caused by social exclusion, and rDLPFC activation may contribute to the involvement of early cognitive resources in the implicit ER process of social pain, thus helping to reduce the subjective negative experience of individuals.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Yen-Yue Lin, Chuan-Chia Chang, Cathy Chia-Yu Huang, Nian-Sheng Tzeng, Yu-Chen Kao, Hsin-An Chang
Summary: Bifrontal tDCS shows rapid and lasting improvement in depression symptoms for both unipolar and bipolar depression patients. Patients also experience enhancements in cognitive performance, anxiety, and psychosocial functioning post-treatment.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neurosciences
Daniela Smirni, Massimiliano Oliveri, Eliana Misuraca, Angela Catania, Laura Vernuccio, Valentina Picciolo, Flora Inzerillo, Mario Barbagallo, Lisa Cipolotti, Patrizia Turriziani
Summary: The study found that cathodal tDCS over the right DLPFC can improve verbal fluency task performance in patients with mild Alzheimer's disease. These improvements may be related to enhancing adaptive patterns of brain activity between functionally connected areas rather than task learning effects.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Neurosciences
Satoshi Yamamoto, Daisuke Ishii, Kiyoshige Ishibashi, Yutaka Kohno
Summary: In this study, the researchers investigated the effects of transcranial direct current electrical stimulation (tDCS) on cognitive tasks related to motor execution. The results showed that a single tDCS session targeting the left dorsolateral prefrontal cortex (DLPFC) improved the performance of cognitive tasks complementary to motor execution. This finding could potentially be used to enhance rehabilitation interventions for patients in the future.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Review
Medicine, General & Internal
James Chmiel, Justyna Chojdak-Lukasiewicz, Jerzy Leszek
Summary: This review discusses the application of transcranial direct current stimulation (tDCS) in treating cocaine addiction. The results indicate that applying tDCS to the right dorsolateral prefrontal cortex (DLPFC) holds promise for reducing drug cravings in individuals with cocaine addiction.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Neurosciences
Vuk Markovic, Carmelo M. Vicario, Fatemeh Yavari, Mohammad A. Salehinejad, Michael A. Nitsche
Summary: Anxiety disorders are prevalent mental disorders and current treatments are moderately successful. Non-invasive brain stimulation methods like rTMS and tDCS have shown potential in modulating fear memory and extinction, particularly when applied over the ventromedial prefrontal cortex. More research is needed to optimize stimulation parameters and protocols for future research and treatment.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Review
Clinical Neurology
Hyun Joon Kim, Nyeonju Kang
Summary: This systematic review and meta-analysis found that bilateral tDCS protocols including anodal tDCS on the right DLPFC and cathodal tDCS on the left DLPFC with multiple sessions may have positive effects on improving symptoms of alcohol use disorder.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Psychiatry
Mitchell Schertz, Yael Karni-Visel, Jacob Genizi, Hofit Manishevitch, Menachem Lam, Ashraf Akawi, Michal Dudai, Andre A. Fenton, Marom Bikson
Summary: The study aimed to examine the safety, feasibility, and efficacy of tDCS combined with CT for treating children with ADHD. Results showed no significant differences between tDCS and sham-tDCS groups post-intervention, with both groups demonstrating improvement in ADHD and executive function measures but mixed results on computerized performance measures. Adverse effects were mild overall, but headaches were experienced by three children in the tDCS group, prompting temporary cessation or removal from the study.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Neurosciences
Shuang Liu, Yuchen He, Dongyue Guo, Xiaoya Liu, Xinyu Hao, Pengchong Hu, Dong Ming
Summary: Recent studies have found that transcranial alternating current stimulation (tACS) has significant effects on emotional attention. In this study, active-tACS at individual alpha frequency (IAF) was delivered to the bilateral dorsolateral prefrontal cortex (dlPFC), resulting in increased alpha entrainment at rest and improved attention in facial emotion processing.
COGNITIVE NEURODYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Giordano D'Urso, Michelangelo Dini, Marta Bonato, Silvia Gallucci, Marta Parazzini, Natale Maiorana, Marco Bortolomasi, Alberto Priori, Roberta Ferrucci
Summary: This open-label pilot study investigated the effect of combining bilateral cerebellar tDCS with bifrontal stimulation in patients with severe depression. The study found that after only five days of treatment, there was a 30% reduction in the severity of depressive symptoms, and younger patients showed greater clinical improvement.
Article
Neurosciences
Vahid Nejati, Maryam Movahed Alavi, Michael A. Nitsche
Summary: The study assessed the impact of transcranial direct current stimulation (tDCS) on inhibitory control in children with ADHD symptoms, finding that stimulation of the right dlPFC plays a crucial role in ongoing inhibition. The effects of tDCS on inhibitory control were partially dependent on symptom severity in children with ADHD.
Article
Geriatrics & Gerontology
Chiara Bagattini, Susana Cid-Fernandez, Martina Bulgari, Carlo Miniussi, Marta Bortoletto
Summary: This study aimed to assess whether age contributes to interindividual variability in the efficacy of transcranial direct current stimulation (tDCS). The results showed opposite effects of tDCS on cognitive tasks between middle-aged (50-64 years) and older (65-81 years) adults, which were supported by the corresponding electroencephalogram results. These findings suggest an age-dependent effect of prefrontal tDCS on cognitive processes.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Psychiatry
Xiaoyu Jiang, Yu Tian, Zhiling Zhang, Changwei Zhou, Jiajin Yuan
Summary: This study aimed to evaluate the effect of transcranial direct current stimulation (tDCS) on behavioral impulsivity in methamphetamine addicts. The results showed that the tDCS intervention counterproductively increased behavioral impulsivity in the addicts. The study suggests that other protocols should be considered for the intervention of methamphetamine addicts in the future.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Yosuke Koshikawa, Keiichiro Nishida, Tomonari Yamane, Masafumi Yoshimura, Ai Onohara, Satsuki Ueda, Ryouhei Ishii, Toshihiko Kinoshita, Yosuke Morishima
Summary: This study aimed to investigate the subcomponents of cognitive inflexibility in major depressive disorder (MDD) and examine the effects of transcranial direct current stimulation (tDCS) on the prefrontal cortex. The results revealed that MDD patients showed increased behavioral cost in task switching, but comparable proactive interference cost to healthy controls. Additionally, anodal tDCS on the dorsomedial prefrontal cortex (DMPFC) improved the response time compared to anodal tDCS on the dorsolateral prefrontal cortex (DLPFC) in MDD.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2022)
Article
Behavioral Sciences
Andrea Gajardo-Vidal, Maxime Montembeault, Diego L. Lorca-Puls, Abigail E. Licata, Rian Bogley, Sabrina Erlhoff, Buddhika Ratnasiri, Zoe Ezzes, Giovanni Battistella, Elena Tsoy, Christa Watson Pereira, Jessica Deleon, Boon Lead Tee, Maya L. Henry, Zachary A. Miller, Katherine P. Rankin, Maria Luisa Mandelli, Katherine L. Possin, Maria Luisa Gorno-Tempini
Summary: This study investigates the potential differences in processing speed and neural correlates among the three variants of Primary Progressive Aphasia (PPA). The findings reveal that non-verbal cognitive abilities, such as processing speed, are significantly impacted in nfvPPA and lvPPA patients compared to healthy controls and svPPA patients. Neuroimaging results confirm the importance of fronto-parietal regions associated with processing speed and executive control.
Article
Behavioral Sciences
Holger Wiese, Tsvetomila Popova, Maya Schipper, Deni Zakriev, Mike Burton, Andrew W. Young
Summary: Previous experiments have shown that brief exposure to unfamiliar individuals leads to the formation of new facial representations, which undergo changes and consolidation within the first day after learning.
Article
Behavioral Sciences
Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Paul Wendiggensen, Veit Roessner, Bernhard Hommel, Christian Beste
Summary: Individuals organize events in their environment by partitioning them into discrete units. This study reveals that the neural activity in the brain plays a critical role in this process, reflecting the key elements of event segmentation.
Article
Behavioral Sciences
Zhenzhen Huo, Zhiyi Chen, Rong Zhang, Junye Xu, Tingyong Feng
Summary: Procrastination has adverse effects on personal growth and social development. Reward sensitivity is positively correlated with procrastination. This study used VBM and RSFC analyses to investigate the neural substrates underlying the association between reward sensitivity and procrastination. The results showed that the functional connectivity of the right parahippocampal gyrus-precuneus mediated the relationship between reward sensitivity and procrastination.
Article
Behavioral Sciences
Stefano Lasaponara, Gabriele Scozia, Silvana Lozito, Mario Pinto, David Conversi, Marco Costanzi, Tim Vriens, Massimo Silvetti, Fabrizio Doricchi
Summary: Cholinergic (Ach), Noradrenergic (NE), and Dopaminergic (DA) pathways are crucial in regulating spatial attention and determining inter-individual differences in temperamental traits. This study found that temperamental traits predict individual differences in the ability to orient spatial attention based on the probabilistic association between cues and targets. These findings highlight the importance of considering temperamental and personality traits in social and professional environments where attention control is essential.
Article
Behavioral Sciences
Darren J. Yeo, Courtney Pollack, Benjamin N. Conrad, Gavin R. Price
Summary: The processing of numerals as visual objects is supported by an Inferior Temporal Numeral Area (ITNA) in the bilateral inferior temporal gyri (ITG). Extant findings suggest some degree of hemispheric asymmetry in how the bilateral ITNAs process numerals. The study found that digit sensitivity did not differ between ITNAs, and digit sensitivity in both left and right ITNAs was associated with calculation skills. The study also revealed a right lateralization in engagement in alphanumeric categorization, and that the right ITNA showed greater discriminability between digits and letters.
Review
Behavioral Sciences
Beste Gulsuna, Abuzer Gungor, Alp O. Borcer, Ugur Ture
Summary: The fiber dissection technique has been used to study the internal structures of the brain, with less focus on white matter. The sagittal stratum, a white matter structure, has not received enough attention and has been a subject of controversy. Recent studies suggest potential functions of the sagittal stratum, emphasizing the importance of understanding this structure accurately.
Article
Behavioral Sciences
Nora Geiser, Brigitte Charlotte Kaufmann, Samuel Elia Johannes Knobel, Dario Cazzoli, Tobias Nef, Thomas Nyffeler
Summary: This study compared the effects of auditory and visual motion stimulation on spatial neglect and found that both interventions were equally effective in improving neglect. Multimodal motion stimulation also improved neglect, but did not show greater improvement than unimodal auditory or visual motion stimulation alone.
Article
Behavioral Sciences
Anna E. Hughes, Anna Nowakowska, Alasdair D. F. Clarke
Summary: This study examines the relationship between search slopes and search efficiency in visual search tasks, introduces the Target Contrast Signal (TCS) Theory, and extends it to a Bayesian multi-level framework. The findings demonstrate that TCS can predict data well, but distinguishing between contrast combination models proves to be difficult.