Article
Fisheries
Jiaying Zheng, Linyong Zhi, Wenji Wang, Na Ni, Youhua Huang, Qiwei Qin, Xiaohong Huang
Summary: This study investigated the characteristics and functions of the TRIM21 gene in orange spotted grouper. The results showed that EcTRIM21 might be involved in host defense against fish virus infections and exerted antiviral activity through positive regulation of the host interferon response.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Shaoli Liu, Xiaoxia Lei, Helong Cao, Zhuqing Xu, Siting Wu, Hong Chen, Linting Xu, Zhouling Zhan, Qiongyue Xu, Jingguang Wei, Qiwei Qin
Summary: FoxO1 plays a significant role in the innate immune response of organisms. The study demonstrates that EcFoxO1 in grouper has antiviral activity against RGNNV and SGIV, and it regulates the immune response of grouper against these infections.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Riming Wu, Jinze Li, Zhenyu Liang, Honglin Han, Jufen Tang, Yu Huang, Bei Wang, Jichang Jian, Jia Cai
Summary: This study identified an SNX5 homolog (EcSNX5) from an orange-spotted grouper and investigated its role in viral infection. It was found that EcSNX5 can influence viral infections by regulating the expression of interferon factors and inflammatory factors, as well as adjusting virus-induced autophagy.
Article
Immunology
Mengshi Sun, Siting Wu, Shaozhu Kang, Jiaming Liao, Luhao Zhang, Zhuqing Xu, Hong Chen, Linting Xu, Xin Zhang, Qiwei Qin, Jingguang Wei
Summary: This study found that the infection of red-spotted grouper nervous necrosis virus (RGNNV) induced the formation of stress granules (SGs) in grouper spleen cells. The SGs particles co-located with the classic SG marker protein eIF3 eta, and some SGs depolymerized under treatment with a translation inhibitor. Inhibition of the PERK kinase significantly inhibited the formation of SGs and decreased the phosphorylation of eIF2 alpha. Overexpression of G3BP1 in Epinephelus coioides inhibited the replication of RGNNV by up-regulating the interferon and inflammatory response.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Xuzhuo Duan, Kaishan Liang, Min Yang, Minlin Zhang, Xiaoling Zuo, Xianze Jia, Zongyang Li, Jie Yu, Liyuan Luo, Jinhong Shan, Huihong Zhao, Yong Zhang, Qiwei Qin, Qing Wang
Summary: The study conducted a genome-wide association study on the resistance of giant groupers to red-spotted grouper nervous necrosis virus (RGNNV), identifying SNP loci and candidate genes that are significantly associated with RGNNV resistance. G protein-coupled receptor 143 (gpr143) was identified as a candidate gene for disease resistance in giant groupers.
Article
Fisheries
Ya Zhang, Liwei Huang, Xiaolin Gao, Qiwei Qin, Xiaohong Huang, Youhua Huang
Summary: This study investigated the role of USP12 in fish RNA virus replication. The results showed that EcUSP12 interacted with viral coat protein to inhibit virus infection and upregulated the transcription of inflammatory factors and interferon-related genes. The findings highlight the important role of EcUSP12 in antiviral immunity.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Siting Wu, Mengshi Sun, Luhao Zhang, Shaozhu Kang, Jiaming Liao, Zheng Zhu, Hong Chen, Zhuqing Xu, Linting Xu, Xin Zhang, Jingguang Wei, Qiwei Qin
Summary: This study cloned and identified a TRAF3 homolog from orange-spotted grouper (EcTRAF3). The results showed that EcTRAF3 plays an important role in the immune response system of fish and negatively regulates the antiviral response.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Xixi Guo, Wenji Wang, Qi Zheng, Qiwei Qin, Youhua Huang, Xiaohong Huang
Summary: This study compared the transcriptomic analysis of SGIV and RGNNV infected grouper cells, revealing the different cell death mechanisms and host immune responses caused by these two viruses. The results also showed the important roles of cytoskeleton and MAPK signaling pathways in SGIV infection, as well as the relationship between post-translational modifications of MAPK signaling-related proteins and viral replication and vacuole formation during RGNNV infection.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Lingfeng Guan, Xiaozhi Wen, Zihan Zhang, Liqun Wang, Xinyue Zhang, Min Yang, Shaowen Wang, Qiwei Qin
Summary: In this study, a novel Rab1 homolog (EcRab1) from Epinephelus coioides was cloned, and its roles during virus infection and host immune responses were investigated. The results showed that EcRab1 inhibited RGNNV infection and positively regulated interferon (IFN) immune and inflammatory responses.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Ni Wang, Chao Zhang, Min Chen, Zheyi Shi, Ying Zhou, Xiaoxiao Shi, Wenwu Zhou, Zengrong Zhu
Summary: In this study, miRNAs in short-winged female adults of the brown planthopper were identified using Solexa sequencing. A total of 905 miRNAs were identified, and 43 miRNAs showed differential expression in different developmental phases. These differentially expressed miRNAs may play important roles in the reproductive development of the brown planthopper.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Fisheries
Jieliang Fan, Jiaying Zheng, Wenjie Lai, Shijia Liu, Xia Liang, Quan Wang, Youhua Huang, Jingguang Wei, Xiaohong Huang, Qiwei Qin, Sheng Zhou
Summary: A new cell line (ECGI-21) was developed from the intestine of grouper, which provides a useful tool for studying gastrointestinal health, viral pathogenesis, and virus-host interaction in vitro.
Article
Fisheries
Zihong Zou, Qi Zheng, Jia Cai, Jufen Tang, Liqun Xia, Pengfei Li, Jichang Jian
Summary: This study characterized a BAG5 homolog gene from orange-spotted grouper and found that it can inhibit viral replication by regulating the expression of interferon and inflammation-related factors. These findings provide valuable insights into the immune response against viral infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Fisheries
Jiaying Zheng, Jiahui Yang, Zemiao Zhang, Xia Liang, Shijia Liu, Ying Pan, Jingguang Wei, Youhua Huang, Xiaohong Huang, Qiwei Qin
Summary: This study evaluated the protective effect of recombinant coat protein (CP) from red-spotted grouper nervous necrosis virus (RGNNV) fused with grouper beta-defensin (DEFB) as an oral vaccine, delivered using Artemia as a biocarrier. The results showed that the CP-DEFB oral vaccination induced higher levels of anti-RGNNV CP antibodies and exhibited higher neutralization potency. The expression levels of immune and inflammatory factors in the spleen and kidney were also significantly increased in the CP-DEFB group. After challenge with RGNNV, the CP-DEFB group showed higher survival rates and lower viral gene transcription levels compared to the control groups.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Oceanography
Qin Yinghui, Liu Jiaoyun, Lu Yuanan, Liu Xueqin
Summary: This study successfully produced monoclonal antibodies specific to red-grouper nervous necrosis virus (RGNNV), which can recognize the virus particles and have the potential for the development of rapid detection methods.
JOURNAL OF OCEAN UNIVERSITY OF CHINA
(2022)
Article
Fisheries
Jiaoyun Liu, Yinghui Qin, Liming Yan, Wanmeng Liu, Herong Shi, Yuanan Lu, Xueqin Liu
Summary: The highly infectious and lethal Red-spotted Grouper Nervous Necrosis Virus (RGNNV) can be effectively neutralized by IgY extracted from the egg yolks of immunized hens. In vivo protection assays on groupers showed significant protection against RGNNV infection, indicating the potential for developing anti-RGNNV products.
Article
Chemistry, Multidisciplinary
Ying Yan, Kai Niu, Wenbo Zhang, Weiming Sun, Yue Jiang, Zhonghao Jiang, Lijuan Zhao, Ming Yang, Baosheng Li, Ying Hou, Guangshe Li, Ming Yang, Shouhua Feng
Summary: Hard materials usually lack energy dissipation mechanism and self-healing ability, but nature solves this problem by creating multiscale interfaces between high-contrast materials like minerals and biopolymers. Inspired by the enamel-dentin junction in nature, researchers have developed an enamel-like crown with beta-FeOOH nanocolumns and a flexible self-healing layer. The top iron oxide layer has high modulus and hardness, while the bottom layer allows for energy dissipation and self-healing. The biomimetic tooth replicate shows promising adhesive properties and inhibits tooth decay-causing bacteria, making it a potential dental material.
Article
Polymer Science
Guang-Bing Luo, Bo Pang, Xing-Qi Luo, Yi Wang, Hong Zhou, Li-Juan Zhao
Summary: This study incorporated 4-tert-butylpyridine into brominated butyl rubber polymer networks to form a reversible ionic bond, preparing a robust self-healing anticorrosive coating. The TBP-BIIR coating showed a protection efficiency of over 94% in strong acid, strong base, and high salt solutions, with a repaired efficiency exceeding 89%. It demonstrated excellent self-healing abilities.
CHINESE JOURNAL OF POLYMER SCIENCE
(2023)
Article
Geography, Physical
Ziqiang Zou, Yu Tao, Yuhao Gao, Zixuan Liu, Wenkai Li, Zhengchao Tian, Lirong Lin, Yangbo He, Jiazhou Chen
Summary: Gully head collapse in southern China's granite soil slopes is caused by the combination of water and gravity, resulting in the loss of soil and water. This study used a five-year high-time-resolution soil moisture dataset to analyze the soil moisture dynamics near a gully head. The results showed that the soil moisture regimes were heterogeneous near the gully head, with a lower soil water content closer to the gully head and greater variation closer to the surface. The study also found that gully head collapse was triggered by heavy rainfall when the soil water content in the deep sandy soil layer reached a certain threshold.
Article
Plant Sciences
Lijuan Zhao, Qiang Cheng
Summary: The pattern recognition receptor AtRLP23 in Arabidopsis thaliana can recognize and trigger pattern-triggered immunity in hybrid poplar cultivar Shanxin in response to flagellin epitope. The heterologous expression of AtRLP23 confers increased broad-spectrum fungal disease resistance in transgenic Shanxin.
MOLECULAR PLANT PATHOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Xin Yan, Si Chen, Zhengyan Pan, Weichen Zhao, Yukui Rui, Lijuan Zhao
Summary: Seeds are facing more difficult conditions due to climate change. Enhancing seeds' stress resilience is crucial for reducing yield loss. In this study, researchers propose using ROS-generating nanoparticles (NPs) to stimulate seeds, which can enhance their stress resilience by triggering stress/immune responses. The results show that pre-stimulated seeds with AgNPs exhibit faster germination, increased seedling vigor, biomass, and root length compared to seeds treated with hydropriming. Additionally, the researchers found that AgNPs stimulation activated stress signaling and defense-related pathways in rice seeds, and this stress memory can last weeks, providing protection to rice seedlings against salt stress and rice blast fungus. This simple nanobiostimulant-based strategy can contribute to sustainable agriculture by maintaining agricultural production and reducing the use of pesticides.
Article
Chemistry, Multidisciplinary
Yi Wang, Yuanjie Xie, Xiangyan Xie, Di Wu, Haitao Wu, Xingqi Luo, Qi Wu, Lijuan Zhao, Jinrong Wu
Summary: A novel strategy of ferric ion-induced salting out and coordination cross-linking is proposed to prepare a hierarchical hydrogel network with tissue-like mechanical properties. The hydrogel shows low elastic modulus, high strength, high toughness, excellent self-recovery ability, fatigue resistance, high water content, good biocompatibility, and multi-sensory capabilities.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Thermodynamics
Qiang Ma, Wenxuan Fu, Lijuan Zhao, Zhenqian Chen, Huaneng Su, Qian Xu
Summary: This work presents a double-layer porous electrode made of carbon paper and graphite felt for a vanadium-iron redox flow battery. A low-porosity carbon paper electrode near the membrane promotes the kinetics of the vanadium redox reaction and improves the hydrophilicity for better mass transfer. A high-porosity graphite felt electrode deposited with copper nanoparticles reduces resistances and enhances electrochemical activity. Experimental results show that the modified battery achieves higher energy efficiency and peak power density compared to a pristine graphite electrode, demonstrating the superiority of this double-layer electrode design.
Article
Environmental Sciences
Si Chen, Zhao Kang, Jose R. Peralta-Videa, Lijuan Zhao
Summary: Research has found that molybdenum disulfide nanosheets have toxic effects on maize seedlings, including inhibiting plant growth and interfering with nutrient uptake. Additionally, the nanosheets have been shown to alter the structure of soil microbial communities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Chemistry, Multidisciplinary
Si Chen, Xin Yan, Jose R. Peralta-Videa, Ziyao Su, Jie Hong, Lijuan Zhao
Summary: The use of silver nanoparticles (AgNPs) in agriculture has been explored as an alternative pesticide, with potential benefits to crop plants. However, further research is needed to understand the mechanisms of interaction between AgNPs and plants. The environmental implications of AgNPs as a replacement for pesticides also need to be assessed.
ENVIRONMENTAL SCIENCE-NANO
(2023)
Article
Fisheries
Lindan Sun, Feng Lin, Binbin Sun, Zhendong Qin, Keping Chen, Lijuan Zhao, Jun Li, Yulei Zhang, Li Lin
Summary: This study found that Scutellaria polysaccharide (SPS) extracted from the Chinese medicinal herb Scutellaria baicalensis can regulate the immune capacity and enhance the antioxidant capacity of the giant freshwater prawn (Macrobrachium rosenbergii), thus improving its survival rate.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Article
Chemistry, Medicinal
Xing-Jie Dai, Li-Juan Zhao, Long-Hua Yang, Ting Guo, Lei-Peng Xue, Hong-Mei Ren, Zhi-Li Yin, Xiao-Peng Xiong, Ying Zhou, Shi-Kun Ji, Hui-Min Liu, Hong-Min Liu, Ying Liu, Yi-Chao Zheng
Summary: In this study, the antipsychotic drug chlorpromazine was identified as an LSD1 inhibitor, and a series of chlorpromazine derivatives were synthesized. Among them, compound 3s showed the most potent inhibitory activity. Compound 3s inhibited LSD1 at the cellular level, downregulated PD-L1 expression in gastric cancer cells, and enhanced T-cell killing response. Animal studies confirmed that compound 3s can inhibit gastric cancer cell proliferation without significant toxicity in immunocompetent mice. These findings suggest that compound 3s may serve as a lead compound for further development to activate T-cell immunity in gastric cancer.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Public, Environmental & Occupational Health
Yue Hong, Wei Xu, Lijuan Zhao
Summary: This study examined the internal influencing mechanism of grandchild care on the depression levels of Chinese grandparents. It found that the experience of caring for grandchildren had a significant negative correlation with the depression level of Chinese grandparents. Furthermore, children's support played an important mediating role in the relationship between caregiving experience and grandparents' depression.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Optics
Zhao Lijuan, Wu Yujing, Xu Zhiniu, Liu Qi
Summary: Optical fiber sensors are highly valued for their simplicity and resistance to interference. Sagnac interferometer based temperature sensors are widely used due to their high sensitivity and ease of production. Special fiber design in Sagnac rings can improve the sensing performance of Sagnac-type temperature sensors.
ACTA PHOTONICA SINICA
(2023)
Article
Thermodynamics
Li-Juan Zhao, Ying LI, Hong-Fei Duan
Summary: To solve the dust treatment problem of the Permian extra thick coal seam mined by Tashan Coal Mine, a comprehensive dust treatment technology research was conducted focusing on the 8106 and 8210 comprehensive discharge faces of the mine. The research analyzed and studied four aspects, including coal seam water injection process, determination of water injection parameters, inspection of water injection and dust reduction effect, and application promotion prospects.
Article
Multidisciplinary Sciences
Lijuan Zhao, Liguo Han, Haining Zhang, Zifeng Liu, Feng Gao, Shijie Yang, Yadong Wang
Summary: In this study, a coal gangue recognition method based on modal fusion of RGB and infrared is proposed to improve the accuracy of coal gangue recognition and the recognition of mixed gangue rate. A fully mechanized coal gangue transportation test bed is built, and RGB and infrared images are obtained. Classification networks including AlexNet, VGG-16, and ResNet-18 are constructed with modal feature fusion. The results show that ResNet networks achieve higher classification accuracy on RGB and infrared image data compared to AlexNet and VGG-16 networks. The feasibility of the modal fusion method in coal gangue recognition is verified with a recognition rate of 97.92%.
