Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2

Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury

(2016) Conrad A. Farrar et al.   JOURNAL OF CLINICAL INVESTIGATION

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1

(2016) Franca Orsini et al.   Journal of Neuroinflammation

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

(2016) József Dobó et al.   Scientific Reports

Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement

(2015) Andrew P. Herbert et al.   JOURNAL OF IMMUNOLOGY

Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4

(2014) Elham Asgari et al.   FASEB JOURNAL

Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway

(2014) Minoru Takahashi et al.   JOURNAL OF IMMUNOLOGY

Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

(2014) Søren E. Degn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigations on Collectin Liver 1

(2013) Esben Axelgaard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heteromeric Complexes of Native Collectin Kidney 1 and Collectin Liver 1 Are Found in the Circulation with MASPs and Activate the Complement System

(2013) M. L. Henriksen et al.   JOURNAL OF IMMUNOLOGY

Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia

(2012) Franca Orsini et al.   CIRCULATION

Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components

(2012) S. Thiel et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

(2012) Dávid Héja et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collectin-11/MASP Complex Formation Triggers Activation of the Lectin Complement Pathway - The Fifth Lectin Pathway Initiation Complex

(2012) Ying Jie Ma et al.   Journal of Innate Immunity

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

(2012) Youssif M. Ali et al.   PLoS Pathogens

Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections

(2011) Hany Ibrahim Kenawy et al.   IMMUNOBIOLOGY

The Role of Mannose-Binding Lectin-Associated Serine Protease-3 in Activation of the Alternative Complement Pathway

(2011) D. Iwaki et al.   JOURNAL OF IMMUNOLOGY

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

(2011) W. J. Schwaeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Mannose-binding Lectin/Ficolin-associated Protein Is Highly Expressed in Heart and Skeletal Muscle Tissues and Inhibits Complement Activation

(2010) Mikkel-Ole Skjoedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Inhibition of the Lectin Pathway of Complement with Phage Display Selected Peptides against Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 and -2: Significant Contribution of MASP-1 to Lectin Pathway Activation

(2010) A. Kocsis et al.   JOURNAL OF IMMUNOLOGY

Collectin 11 (CL-11, CL-K1) Is a MASP-1/3-Associated Plasma Collectin with Microbial-Binding Activity

(2010) S. Hansen et al.   JOURNAL OF IMMUNOLOGY

Paths reunited: Initiation of the classical and lectin pathways of complement activation

(2009) Russell Wallis et al.   IMMUNOBIOLOGY

Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

(2009) Minoru Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation

(2009) S. E. Degn et al.   JOURNAL OF IMMUNOLOGY

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

(2009) A. Dieudonne-Vatran et al.   JOURNAL OF IMMUNOLOGY

The down-stream effects of mannan-induced lectin complement pathway activation depend quantitatively on alternative pathway amplification

(2009) Morten Harboe et al.   MOLECULAR IMMUNOLOGY