An overview of Ca2+mobilization assays in GPCR drug discovery

A comparison of fluorescent Ca2+ indicators for imaging local Ca2+ signals in cultured cells

(2015) Jeffrey T. Lock et al.   CELL CALCIUM

Fast kinetics of calcium signaling and sensor design

(2015) Shen Tang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The therapeutic potential of orphan GPCRs, GPR35 and GPR55

(2015) Derek M. Shore et al.   Frontiers in Pharmacology

Measurement of Inositol 1,4,5-Trisphosphate in Living Cells Using an Improved Set of Resonance Energy Transfer-Based Biosensors

(2015) Gergő Gulyás et al.   PLoS One

A Cell-Based Functional Assay Using a Green Fluorescent Protein-Based Calcium Indicator dCys-GCaMP

(2014) Bin Cai et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Contrasting actions of group I metabotropic glutamate receptors in distinct mouse striatal neurones

(2014) John G. Partridge et al.   JOURNAL OF PHYSIOLOGY-LONDON

A generic microfluidic biosensor of G protein-coupled receptor activation—monitoring cytoplasmic [Ca2+] changes in human HEK293 cells

(2013) Margriet Roelse et al.   BIOSENSORS & BIOELECTRONICS

Monitoring intracellular calcium in response to GPCR activation using thin-film silicon photodiodes with integrated fluorescence filters

(2013) S.A.M. Martins et al.   BIOSENSORS & BIOELECTRONICS

Synthesis and properties of Asante Calcium Red—A novel family of long excitation wavelength calcium indicators

(2013) Krzysztof L. Hyrc et al.   CELL CALCIUM

Circular permutated red fluorescent proteins and calcium ion indicators based on mCherry

(2013) H. J. Carlson et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development

(2012) Bettina C. Kirchmaier et al.   DEVELOPMENTAL BIOLOGY

Disentangling Picosecond Events That Complicate the Quantitative Use of the Calcium Sensor YC3.60

(2012) S. P. Laptenok et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Luminescent proteins for high-speed single-cell and whole-body imaging

(2012) Kenta Saito et al.   Nature Communications

An Expanded Palette of Genetically Encoded Ca2+ Indicators

(2011) Y. Zhao et al.   SCIENCE

Design and application of genetically encoded biosensors

(2011) Amy E. Palmer et al.   TRENDS IN BIOTECHNOLOGY

Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays

(2010) Steven J Charlton et al.   BRITISH JOURNAL OF PHARMACOLOGY

G protein-coupled receptors: novel targets for drug discovery in cancer

(2010) Rosamaria Lappano et al.   NATURE REVIEWS DRUG DISCOVERY

A Photoprotein in Mouse Embryonic Stem Cells Measures Ca2+ Mobilization in Cells and in Animals

(2010) Silvia Cainarca et al.   PLoS One

Auto-Luminescent Genetically-Encoded Ratiometric Indicator for Real-Time Ca2+ Imaging at the Single Cell Level

(2010) Kenta Saito et al.   PLoS One

Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

(2010) Sandip Patel et al.   TRENDS IN CELL BIOLOGY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

Image analysis of Ca2+ signals as a basis for neurotoxicity assays: Promises and challenges

(2009) Rola Barhoumi et al.   NEUROTOXICOLOGY AND TERATOLOGY

Inositol trisphosphate and calcium signalling mechanisms

(2008) Michael J. Berridge   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genetically Encoded Calcium Indicators

(2008) Marco Mank et al.   CHEMICAL REVIEWS

Detection of molecular tags with an integrated amorphous silicon photodetector for biological applications

(2008) J.P. Conde et al.   JOURNAL OF NON-CRYSTALLINE SOLIDS

Characterization and Subcellular Targeting of GCaMP-Type Genetically-Encoded Calcium Indicators

(2008) Tianyi Mao et al.   PLoS One

Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System

(2008) Neil C Chi et al.   PLOS BIOLOGY