Article
Medicine, Research & Experimental
Tamas Benkoe, Julia Koenig, Jens M. Theysohn, Clemens Schotten, Fuat H. Saner, Juergen Treckmann, Sonia Radunz
Summary: This study compared the recurrence of HCC after liver transplantation following TACE or radioembolization bridging treatment. The results showed no significant difference in HCC recurrence and overall survival between the radioembolization group and TACE group. Multivariable analysis found recipient age, gender, tumor necrosis, and microvascular invasion to be associated with HCC recurrence.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2022)
Article
Engineering, Biomedical
Guorong Jia, Tao Wang, Rou Li, Xiao Li, Gaofeng Sun, Wei Chen, Ye Peng, Chao Cheng, Jijin Yang, Changjing Zuo
Summary: In interventional treatment, the combination therapy of transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) using multifunctional nanoparticles shows promise in overcoming drug resistance and improving therapeutic effect in hepatocellular carcinoma (HCC).
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Oncology
Sung Won Chung, Heejin Cho, Hyunjae Shin, Jeayeon Park, Ju Yeon Kim, Ji Hoon Hong, Moon Haeng Hur, Min Kyung Park, Yun Bin Lee, Su Jong Yu, Myungsu Lee, Yoon Jun Kim, Jin Chul Paeng, Jung-Hwan Yoon, Jin Wook Chung, Jeong-Hoon Lee, Hyo-Cheol Kim
Summary: Although TARE is a treatment option for large HCC, some patients are ineligible due to high LSF. This study evaluated if TACE treatment for TARE-ineligible patients was associated with early HCC progression.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Sun Young Yim, Ho Soo Chun, Jae Seung Lee, Ji-Hwan Lim, Tae Hyung Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Gyoung Min Kim, Jong Yun Won, Yeon Seok Seo, Yun Hwan Kim, Soon Ho Um, Do Young Kim
Summary: This study investigated the long-term clinical outcomes of patients with hepatocellular carcinoma (HCC) treated with transarterial radioembolization (TARE) in a multi-medical center in Korea. The results showed that TARE is safe and effective for patients with early to advanced HCC.
Review
Oncology
Haomin Lin, Bin Luo, Fangyi Peng, Cheng Fang, Yu Gan, Xiaoli Yang, Bo Li, Yaling Li, Song Su
Summary: The aim of this study was to identify predictors of successful downstaging of unresectable hepatocellular carcinoma (HCC) outside Milan criteria (MC) by transarterial chemoembolization (TACE). The study found that the number and size of tumors, portal vein tumor thrombosis, hepatitis B surface antigen, and alpha-fetoprotein are significant predictors of successful downstaging of unresectable HCC in patients treated with TACE outside the MC.
INVESTIGATIONAL NEW DRUGS
(2022)
Review
Multidisciplinary Sciences
Simon Lemieux, Alex Buies, Alexis F. Turgeon, Julie Hallet, Gaetan Daigle, Francois Cote, Steeve Provencher
Summary: Yttrium-90 transarterial radioembolization did not show significant effects on survival, progression-free survival, time to progression, disease control rate, and incidence of gastro-intestinal ulcers in non-surgical HCC patients, but was associated with significantly lower rates of grade >= 3 adverse events. Further randomized controlled trials are needed to determine optimal treatment.
Article
Oncology
Lisa Ngo, Ahmed Elnahla, Abdallah S. Attia, Mohamed Hussein, Eman A. Toraih, Emad Kandil, Mary Killackey
Summary: This meta-analysis found that for neuroendocrine liver metastases, TACE treatment is associated with better overall survival compared to TARE treatment, despite no significant differences in hepatic progression-free survival and tumor response between the two methods. Further randomized controlled trials are needed to confirm these findings and determine if certain subpopulations benefit from different transarterial methods.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Review
Oncology
Victor Lopez-Lopez, Kohei Miura, Christoph Kuemmerli, Antonio Capel, Dilmurodjon Eshmuminov, David Ferreras, Alberto Baroja-Mazo, Pedro Cascales-Campos, Maria Isabel Jimenez-Mascunan, Jose Antonio Pons, Maria Isabel Castellon, Francisco Sanchez-Bueno, Ricardo Robles-Campos, Pablo Ramirez
Summary: The usefulness of TARE in the treatment of borderline-resectable HCC has been endorsed and recommended, but its role in liver transplant is still under debate and lacks clear guidelines.
Review
Oncology
Rou Li, Danni Li, Guorong Jia, Xiao Li, Gaofeng Sun, Changjing Zuo
Summary: Hepatocellular carcinoma is a major type of primary liver tumor, with TARE being an alternative treatment for patients who failed other therapies or for those in need of downstaging treatment. Various radionuclides can be used in TARE for liver cancer, providing therapeutic benefits and diagnostic information to guide treatment.
FRONTIERS IN ONCOLOGY
(2021)
Review
Surgery
Daniel Seehofer, Henrik Petrowsky, Stefan Schneeberger, Eric Vibert, Jens Ricke, Gonzalo Sapisochin, Jean-Charles Nault, Thomas Berg
Summary: Patients with HCC outside the Milan criteria require more detailed patient selection, with additional parameters such as AFP levels, new criteria like WE/Metroticket 2.0, PET scans, and tumor biopsies playing a crucial role in the selection process. The clinical course during downstaging, especially tumor and AFP response, is of paramount importance as a final selection tool.
TRANSPLANT INTERNATIONAL
(2022)
Article
Gastroenterology & Hepatology
Rui Feng, De-Xin Cheng, Tao Song, Long Chen, Kai-Ping Lu
Summary: This study investigated the clinical value and safety of TACE alone and combined with TARE in the treatment of progression in patients with advanced HCC. The results showed that TACE combined with TARE is more effective in treating advanced HCC, improving postoperative survival rate, reducing adverse effects, and having a better safety profile.
WORLD JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Gastroenterology & Hepatology
Xiao Wu, Allison Kwong, Michael Heller, R. Peter Lokken, Nicholas Fidelman, Neil Mehta
Summary: Transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) are commonly used modalities for patients with hepatocellular carcinoma (HCC) awaiting liver transplant. This study compared the cost-effectiveness of TACE and TARE in downstaging patients with HCC, and found that TARE is the more cost-effective strategy.
LIVER TRANSPLANTATION
(2023)
Article
Multidisciplinary Sciences
A. Bogdanovic, P. Bulajic, D. Masulovic, N. Bidzic, M. Zivanovic, D. Galun
Summary: The study compared short- and long-term outcomes of patients with huge HCC who underwent potentially curative LR or TACE, finding that LR group had higher overall survival rates both before and after propensity score matching. Total bilirubin and TACE treatment were identified as independent prognostic factors associated with long-term survival.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Audrey Fohlen, Remi Beaudouin, Arnaud Alves, Karine Bouhier-Leporrier, Christophe Pasik, Jean-Pierre Pelage
Summary: This study evaluated the tolerability and clinical, biological and radiological tumor response and survival rates in patients with unresectable neuroendocrine liver metastases treated by trans-catheter arterial embolization with conventional chemoembolization, using streptozocin, Lipiodol, and embolization microspheres. The results showed that this procedure using streptozocin is an effective and well-tolerated palliative option for patients with unresectable neuroendocrine liver metastases, with a high objective response rate and non-progressive disease rate. The overall survival rate at different time points was also encouraging.
Article
Gastroenterology & Hepatology
Ahmed Gabr, Laura Kulik, Samdeep Mouli, Ahsun Riaz, Rehan Ali, Kush Desai, Ronald A. Mora, Daniel Ganger, Haripriya Maddur, Steven Flamm, Justin Boike, Christopher Moore, Bartley Thornburg, Ali Alasadi, Talia Baker, Daniel Borja-Cacho, Nitin Katariya, Daniela P. Ladner, Juan Carlos Caicedo, Robert J. Lewandowski, Riad Salem
Summary: This study presents the long-term outcomes of liver transplantation for HCC patients bridged or downstaged by Y90, demonstrating the effectiveness of Y90 in HCC treatment and the benefit of achieving extensive or complete necrosis for improved recurrence-free survival.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jules Gregory, Lambros Tselikas, Caroline Allimant, Thierry de Baere, Irene Bargellini, Jon Bell, Jose Ignacio Bilbao, Antoine Bouvier, Julius Chapiro, Carlo Chiesa, Thomas Decaens, Alban Denys, Rafael Duran, Julien Edeline, Etienne Garin, Julien Ghelfi, Thomas Helmberger, Farah Irani, Marnix Lam, Robert Lewandowski, David Liu, Romaric Loffroy, David C. Madoff, Charles Mastier, Riad Salem, Bruno Sangro, Daniel Sze, Valerie Vilgrain, Michael Vouche, Boris Guiu, Maxime Ronot
Summary: This study aimed to define a textbook outcome (TO) for selective internal radiation therapy (SIRT) of hepatocellular carcinoma. The final TO, determined through expert opinions and an international survey, is a multidimensional standardization tool suitable for routine care, clinical round, and research.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Editorial Material
Gastroenterology & Hepatology
Brandon M. Caldwell, Ahmed Gabr, Pouya Entezari, Alex Sher, Edward Kim, Guy E. Johnson, Riad Salem, Robert J. Lewandowski
LIVER TRANSPLANTATION
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Courtney Sperry, Asad Malik, Allison Reiland, Bartley Thornburg, Rajesh Keswani, Muhammed Sufyaan Ebrahim Patel, Aziz Aadam, Anthony Yang, Ezra Teitelbaum, Riad Salem, Ahsun Riaz
Summary: The study evaluated the feasibility, effectiveness, and outcomes of percutaneous cholecystostomy drain internalization in patients with calculous cholecystitis who were not surgical candidates. Dual cholecystoduodenal stent placement was attempted in 17 patients, with successful placement in 13 patients. The 1-year patency rate was 77%.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrew M. Chiu, Rohan Savoor, Andrew C. Gordon, Ahsun Riaz, Kent T. Sato, Elias Hohlastos, Riad Salem, Robert J. Lewandowski
Summary: A retrospective study found that yttrium-90 radiation segmentectomy is a safe and effective treatment for oligo-metastatic secondary hepatic malignancies, achieving high disease control rate.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Suresh Vedantham, Kush R. Desai, Ido Weinberg, William Marston, Ronald Winokur, Sheena Patel, Kanti Pallav Kolli, Ezana Azene, Kari Nelson
Summary: This paper summarizes the Society of Interventional Radiology (SIR)'s updated position on endovascular management of acute iliofemoral deep vein thrombosis (DVT). Through literature search and expert consensus, 17 recommendations were developed for the use of endovascular venous interventions in treating acute iliofemoral DVT. The study considers endovascular thrombus removal as an acceptable treatment option in selected patients.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Psychology, Clinical
Alyssa M. Vela, Michelle Callegari, Leah Goudy, Cameron Cozzi, Meg Gibson, Michael J. Rooney, Juan Carlos Caicedo
Summary: Despite increased attention to DEI within academic medicine, representation, lack of workforce diversity, and bias within medicine remain persistent problems. A study of surgery departments in the United States found that only 16% included DEI-specific information on their websites, and less than seven percent reported having a DEI committee. This lack of public information may have implications for recruitment, retention, and patient care.
JOURNAL OF CLINICAL PSYCHOLOGY IN MEDICAL SETTINGS
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Gabriel M. Knight, Andrew C. Gordon, Vanessa Gates, Abhinav Talwar, Ahsun Riaz, Riad Salem, Robert Lewandowski
Summary: Yttrium-90 transarterial radioembolization (TARE) has evolved from a salvage or palliative therapy to a versatile and potentially curative treatment for liver cancer patients. Personalized radiation dosimetry has been proven to improve tumor response and overall survival while ensuring patient safety. This review covers the imaging techniques, dosimetry methods, and future developments in TARE.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Srirajkumar Ranganathan, Ahmed Gabr, Pouya Entezari, Andrew C. Gordon, Ahsun Riaz, Kush Desai, Bartley Thornburg, Laura Kulik, Aparna Kalyan, Riad Salem, Robert J. Lewandowski
Summary: This study aims to assess liver function trends in patients with intermediate-stage hepatocellular carcinoma (HCC) who underwent yttrium-90 transarterial radioembolization (TARE). The results suggest that TARE does not negatively affect liver function and allows patients with HCC to be candidates for systemic therapy. The study shows that the median time to persistent CP-B HCC in patients who underwent TARE was 15.4 months.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Suresh Vedantham, Ido Weinberg, Kush R. Desai, Ronald Winokur, Kanti Pallav Kolli, Sheena Patel, Kari Nelson, William Marston, Ezana Azene
Summary: SIR stated their position on the endovascular management of chronic iliofemoral venous obstruction with metallic stents. They believe that endovascular stent placement may be beneficial for selected patients, but the risks and benefits need further quantification through randomized studies. SIR recommends careful patient selection, appropriate stent sizing and quality procedural technique, and urgent completion of well-designed studies. Close patient follow-up is also recommended for optimal antithrombotic therapy, durable symptom response, and early identification of adverse events.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Riad Salem, Allison Reiland, Bartley Thornburg
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Akhilesh K. Sista, Suresh Vedantham, Susan R. Kahn, Kush R. Desai, Samuel Z. Goldhaber
Summary: The 2015 Research Consensus Panel identified a rigorous randomized trial of catheter-directed therapy plus anticoagulation versus anticoagulation alone as the highest research priority for submassive pulmonary embolism (PE). This update presents the current state of endovascular PE practice and highlights the Pulmonary Embolism-Thrombus Removal with Catheter-Directed Therapy trial, the main output from the RCP.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Kush R. Desai
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)