Article
Chemistry, Applied
Christopher M. A. Parlett, Hamidreza Arandiyan, Lee J. Durndell, Mark A. Isaacs, Antonio Torres Lopez, Roong J. Wong, Karen Wilson, Adam F. Lee
Summary: The article demonstrates a method for continuous flow synthesis of SBA-15 at high yield at 80 degrees C using a simple tube reactor. The resulting SBA-15 exhibits excellent textural properties and far higher productivity than previously reported in batch or flow synthesis.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Environmental Sciences
Zeinab Ezzeddine, Isabelle Batonneau-Gener, Yannick Pouilloux
Summary: The removal of zinc ions from water was studied using two types of ordered mesoporous silica (SBA-15 and SBA-16). Both materials were modified with APTES and EDTA through post grafting methods. The modified adsorbents were characterized by various analytical techniques, and the structural integrity was maintained. Optimal adsorption conditions and maximum adsorption capacity were determined through experimental tests, and the regenerated adsorbent showed no significant decline in adsorption efficiency.
Article
Physics, Applied
Fnu Gorky, Shelby R. Guthrie, Courtney S. Smoljan, James M. Crawford, Moises A. Carreon, Maria L. Carreon
Summary: The mesoporous SBA-15 silica material demonstrated significantly higher efficiency in synthesizing ammonia through atmospheric dielectric barrier discharge plasma, mainly due to its hierarchically ordered pore structure that facilitates the diffusion of plasma discharge into the pores.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Chemistry, Applied
Zhe Wang, Rui Sun, Pengwei Wang, Wei Wang
Summary: This study successfully prepared rod-shaped SBA-15 nanoparticles with 2-3 mesopore channels, showing potential for biomedical applications. Through a specific preparation method, SBA-15NPs exhibited higher surface area, pore volume, and faster adsorption rate in enzyme adsorption tests compared to conventional rod-shaped SBA-15.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Chemistry, Physical
Hongxia Liu, Yijia Lao, Jiayi Wang, Junjie Jiang, Chuanbai Yu, Yuanli Liu
Summary: The development of composite materials with functional additives proved to be an effective way to improve or supplement the required properties of polymers. In this study, mesoporous silica (SBA-15) with different pore sizes were used as functional additives to prepare SBA-15/PF (phenolic resin) nanocomposites. The results revealed that the pore sizes of SBA-15 have a significant effect on the resulting SBA-15/PF hybrid and SBA-15/PF nanocomposites, with enhanced thermal and frictional properties.
Article
Materials Science, Ceramics
Anupam Maity, Subha Samanta, Shubham Roy, Debasish Biswas, Dipankar Chakravorty
Summary: Nanocomposites with different glass compositions were synthesized using a sol-gel process, revealing the presence of Ni2+/Ni3+ ions through TEM and XPS studies. These materials exhibited ideal specific capacity and magnetodielectric parameters, making them suitable for manufacturing supercapacitor devices.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2021)
Article
Chemistry, Inorganic & Nuclear
Selvakumari Ulagesan, Madhappan Santhamoorthy, Thi Phan Vy Phan, Krishnapandi Alagumalai, Kokila Thirupathi, Seong-Cheol Kim, Taek-Jeong Nam, Youn-Hee Choi
Summary: In this study, a mesoporous silica material containing amidoxime ligand groups was successfully synthesized through surface modification. The resulting SBA-15@AMI NPs exhibited a high concentration of amidoxime ligands on the surface, making them suitable for pH-responsive drug delivery applications in cancer therapy.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
Safora Purrostam, Zohreh Rahimi-Ahar, Aziz Babapoor, Ali Nematollahzadeh, Iman Salahshoori, Ahmad Seyfaee
Summary: In this study, a melamine-functionalized mesoporous silica-SBA-15 adsorbent was synthesized to remove Cr(VI) from wastewater. The adsorbent was prepared through hydrothermal synthesis and post-synthesis modification with 3-aminopropyl trimethoxy silane and melamine. The adsorption of Cr(VI) was studied and characterized using various techniques. The optimal conditions for adsorption were determined, and the results showed that the functionalization of the adsorbent surface increased the adsorption efficiency and capacity. The highest adsorption capacity for Cr(VI) was about 50 mg/g.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Applied
Silvia Leccese, Thomas Onfroy, Adjele Wilson, Diana Kirilovsky, Sandra Casale, Saremble Guira, Mohamed Selmane, Claude Jolivalt, Alberto Mezzetti
Summary: This study focuses on the immobilization of the photoactive Orange Carotenoid Protein (OCP) on mesoporous silica nanoparticles and investigates its structural characterization. The results highlight the enhanced immobilization of OCP by pre-photoactivation, leading to photochromic nanoparticles. The study also explores the possibility of releasing OCP from the nanoparticles and suggests potential applications in nanoscale optical devices and antioxidant drug delivery.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Fabio S. De Vicente, Leandro X. Moreno, Marcus V. A. Prado, Luis M. G. Abegao, Leandro A. Melo, Jose J. Rodrigues Jr, Marcio A. R. C. Alencar
Summary: Mesoporous silica SBA-15 with a hexagonal pore structure and high surface area is suitable for filling with luminescent chromophores for optical and photonic applications. Experiments show that SBA-15 infiltrated with RB can generate tunable random laser emissions, indicating the potential for developing solid-state random lasers.
PHYSICAL REVIEW MATERIALS
(2021)
Article
Pharmacology & Pharmacy
Klara Szentmihalyi, Szilvia Klebert, Zoltan May, Eszter Bodis, Miklos Mohai, Laszlo Trif, Tivadar Feczko, Zoltan Karoly
Summary: By immobilizing MTZ molecules on mesoporous silica carriers, this study achieved higher fixation rates and faster dissolution rates, providing a new approach to reduce drug dosage while maintaining high efficiency.
Article
Engineering, Environmental
Eman F. Aboelfetoh, Mohamed E. Zain Elabedien, El-Zeiny M. Ebeid
Summary: This study presents an effective fixed-bed column for wastewater treatment by loading nanoparticles and various fillers to remove pollutants from industrial wastewater. The selection of optimal pH and kinetic models can enhance the efficiency of wastewater treatment.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Physical
Lishil Silvester, Quentin Touloumet, Aiman Kamaruddin, Fernand Chassagneux, Georgeta Postole, Aline Auroux, Laurence Bois
Summary: This study investigated the influence of silica functionalization on SCa composites and found that the nonfunctionalized composite demonstrated the highest water sorption rate and heat storage capacity. The water uptake of all SCa composites was enhanced compared to pure CaCl2 due to the good dispersion of salt particles in the SBA pores.
ACS APPLIED ENERGY MATERIALS
(2021)
Article
Engineering, Chemical
Wenyong Wang, Guohao Wu, Tao Zhu, Yin Yang, Yuanyuan Zhang
Summary: The selective removal of Pb(II) ions was achieved by modifying mesoporous silica materials, SBA-NS and SBA-ENS, which showed improved adsorption performance and selectivity for Pb(II) in binary metal ion systems. The experimental results indicated that the imine N atoms on the two adsorbents played a dominant role during the Pb(II) sorption process, providing a potential solution for waste water treatment and lead recycling.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Green & Sustainable Science & Technology
Huanting Hu, Kangkang Miao, Xiaolin Luo, Sifan Guo, Xueqin Yuan, Fei Pei, Huaming Qian, Guodong Feng
Summary: The study demonstrated that Cu-doped SBA-15 with a Cu/Si molar ratio of 0.133 exhibited the best catalytic activity in the oxidative degradation of high-concentration chlorophenols, with an apparent reaction rate constant of 0.170 min(-1) for 4-chlorophenol. After 300 minutes of reaction, the total organic carbon content in the solution decreased to 23.8%. The results suggest the potential of Cu-doped SBA-15 for effective treatment of industrial wastewater containing high levels of chlorophenols.
JOURNAL OF CLEANER PRODUCTION
(2021)
Review
Polymer Science
Athira John, Klementina Pusnik Cresnar, Dimitrios N. Bikiaris, Lidija Fras Zemljic
Summary: Due to increasing consumer demand, the food packaging industry is opting for packaging materials with active functions. Active compounds are added as coatings to the base packaging material for maintaining physicochemical properties and enhancing efficiency. Colloidal systems, specifically colloidal dispersions, are potential candidates for active coatings due to their controlled release and uniform distribution. This review focuses on analyzing the advantages of using natural bio-based substances and packaging materials like PLA, considering consumer awareness and environmental concerns. It also briefly discusses the antiviral concept through surface application, addressing the current pandemic crisis and cross-infection prevention.
Article
Polymer Science
Dimitra Kourtidou, Dimitrios Karfaridis, Thomas Kehagias, George Vourlias, Dimitrios N. Bikiaris, Konstantinos Chrissafis
Summary: Poly(ethylene 2,5-furandicarboxylate) (PEF) nanocomposites reinforced with Graphene nanoplatelets (GNPs) and Carbon nanotubes (CNTs) were synthesized in situ in this study. The incorporation of fillers resulted in changes in lamellar thickness and increased crystallinity of the PEF matrix, thus broadening its potential applications.
Article
Chemistry, Multidisciplinary
Eleftheria Xanthopoulou, Zoi Terzopoulou, Alexandra Zamboulis, Savvas Koltsakidis, Dimitrios Tzetzis, Katerina Peponaki, Dimitris Vlassopoulos, Nathanael Guigo, Dimitrios N. Bikiaris, George Z. Papageorgiou
Summary: The synthesis of a new high molecular weight aliphatic-aromatic polyester, poly(hexylene vanillate) (PHV), using 4-(6-hydroxyethoxy)-3methoxybenzoic acid via a two-stage melt polycondensation method is reported. The success of the polymerization was confirmed using nuclear magnetic resonance spectroscopy (NMR) and Fourier transformed infrared spectroscopy (FTIR), while the number average molecular weight (Mn) was estimated by size-exclusion chromatography (SEC). The thermal behavior, mechanical properties, and processability of PHV were investigated, showing its potential as a biobased polyester material.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Medicinal
Georgia Michailidou, Alexandra Zamboulis, Dimitrios N. Bikiaris
Summary: In this study, chitosan was derivatized with 2-methoxy-4-vinylphenol in different ratios. The CS-MVP derivatives were characterized and their antioxidant activity was assessed. Blends between CS and CS-MVP in different ratios were prepared and their miscibility was examined. Highly concentrated inks with shear thinning behavior were successfully formed, which could be applied in biomedical and drug delivery applications.
Article
Biochemistry & Molecular Biology
Eleni Evgenidou, Konstantina Vasilopoulou, Lelouda-Athanasia Koronaiou, George Kyzas, Dimitrios Bikiaris, Dimitra Lambropoulou
Summary: This study investigates the photocatalytic transformation of the antiviral drug abacavir using different advanced oxidation processes (AOPs) and assesses their efficiency in removing abacavir in different matrices. The results show that all processes are effective in eliminating abacavir within a short time, but the presence of organic matter or inorganic constituents can hinder the process. The study also identifies major transformation products and their evolution profiles in different matrices, indicating different transformation pathways dominate in each matrix. The toxicity prediction of the major transformation products suggests that only hydroxylation can detoxify the treated solution.
Article
Biochemistry & Molecular Biology
Giulia Fredi, Edoardo Zonta, Alessandro Dussin, Dimitrios N. Bikiaris, George Z. Papageorgiou, Luca Fambri, Andrea Dorigato
Summary: This study successfully prepared and characterized polylactide/poly(propylene 2,5-furandicarboxylate) (PLA/PPF) and polylactide/poly(butylene 2,5-furandicarboxylate) (PLA/PBF) blends in bulk and fiber forms, and investigated the influence of poly(alkylene furanoate) (PAF) concentration and compatibilization on their physical, thermal, and mechanical properties. Both blends were successfully compatibilized by Joncryl, which improved the interfacial adhesion and reduced the size of PPF and PBF domains. PBF was found to effectively toughen PLA in bulk samples, while PPF showed no significant plasticizing effects. In fiber samples, both PPF and PBF exhibited plasticizing effects, resulting in significantly higher strain at break values compared to neat PLA.
Article
Chemistry, Multidisciplinary
Amit Kumar Singh, Dimitrios A. A. Giannakoudakis, Michael Arkas, Konstantinos S. S. Triantafyllidis, Vaishakh Nair
Summary: In this study, composites of bismuth oxyhalide nanoparticles and lignin-based biochar were synthesized for the photocatalytic and adsorptive remediation of methyl orange dye (MO). The optimized conditions achieved 100% degradation of MO after 60 minutes of light exposure. The incorporation of biochar enhanced the photocatalytic performance of the BiOCl photocatalyst, making it a promising and eco-friendly nanomaterial for wastewater treatment.
Article
Chemistry, Multidisciplinary
Michael Arkas, Konstantinos Giannakopoulos, Evangelos P. Favvas, Sergios Papageorgiou, George V. Theodorakopoulos, Artemis Giannoulatou, Michail Vardavoulias, Dimitrios A. Giannakoudakis, Konstantinos S. Triantafyllidis, Efthalia Georgiou, Ioannis Pashalidis
Summary: Two different silica conformations, xerogels and nanoparticles, were tested for uranyl cation sorption at low pHs using dendritic poly (ethylene imine) as a mediator. The study investigated the effect of factors such as temperature, electrostatic forces, adsorbent composition, pollutant accessibility, and organic matrix properties to determine the optimal formulation for water purification. Through various techniques including spectroscopy, light scattering, porosimetry, TGA, and SEM, the results showed that both adsorbents exhibited extraordinary sorption capacities. Xerogels were cost-effective and could be used to create composite purification devices.
Article
Pharmacology & Pharmacy
Georgia K. K. Pouroutzidou, Lambrini Papadopoulou, Maria Lazaridou, Konstantinos Tsachouridis, Chrysanthi Papoulia, Dimitra Patsiaoura, Ioannis Tsamesidis, Konstantinos Chrissafis, George Vourlias, Konstantinos M. M. Paraskevopoulos, Antonios D. D. Anastasiou, Dimitrios N. N. Bikiaris, Eleana Kontonasaki
Summary: In this study, composite akermanite/PLGA/NPs/MOX-loaded scaffolds were fabricated using silica-based nanoparticles enriched with calcium and magnesium, as well as copper and strontium ions, combined with the sol-gel method. The results showed that the composite scaffolds exhibited improved mechanical properties, degradation performance, and hemocompatibility. Moreover, they demonstrated a prolonged release profile of moxifloxacin, making them promising for bone regeneration applications.
Article
Materials Science, Composites
Iouliana Chrysafi, Nina Maria Ainali, Eleftheria Xanthopoulou, Alexandra Zamboulis, Dimitrios N. Bikiaris
Summary: This study investigates the thermal degradation of PESu/hemp fiber composites and identifies that the main degradation pathway is the β-hydrogen scission of the polymeric backbone. The results provide valuable thermal behavior information for the application of these composites as alternative wood plastic composites (WPCs).
JOURNAL OF COMPOSITES SCIENCE
(2023)
Article
Chemistry, Physical
Neda Malesic-Eleftheriadou, Dimitrios G. Trikkaliotis, Eleni Evgenidou, George Z. Kyzas, Dimitrios N. Bikiaris, Dimitra A. Lambropoulou
Summary: The study focused on the synthesis, characterization, and application of new bio-based chitosan derivatives for the adsorption removal of pharmaceutical mixtures from aqueous matrices. Six chitosan/polyvinyl alcohol materials with varying concentrations of graphene oxide and reduced graphene oxide were synthesized. The composites with the highest concentration of GO and rGO showed the highest adsorption capacity, while valsartan and diclofenac exhibited the highest removal efficiency. The Langmuir model provided a better fit for the experimental data, and the adsorption capacity increased with temperature.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Analytical
Lorenzo Martello, Nina Maria Ainali, Dimitrios N. Bikiaris, Dimitra A. Lambropoulou
Summary: In this study, novel molecularly imprinted polymers (MIPs) were synthesized using penconazole as the template and various combinations of functional monomers and cross-linkers. The MIPs showed higher affinity for triazole pesticides in apple juice compared to non-imprinted polymers. The developed MIP-d-SPE-LC-MS method exhibited excellent selectivity and good performance for the enrichment and determination of triazole compounds in apple juice and river water samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Katerina Papadopoulou, Evangelia Tarani, Nina Maria Ainali, Konstantinos Chrissafis, Christian Wurzer, Ondrej Masek, Dimitrios N. Bikiaris
Summary: In this study, PBSu and its bionanocomposites containing different amounts of biochar were prepared to investigate their thermal stability and decomposition mechanism. XPS was used to analyze the surface area of biochar and PBSu/biochar nanocomposites, and it was found that only physical interactions were present between PBSu matrix and biochar nanoadditive. TGA and Py-GC/MS were used to study the thermal stability and decomposition pathway, showing that the addition of biochar slightly reduced the thermal stability of PBSu nanocomposites and affected the decomposition mechanism.
Article
Chemistry, Multidisciplinary
Mariusz Barczak, Dorota Pietras-Ozga, Moaaz K. K. Seliem, Giacomo de Falco, Dimitrios A. A. Giannakoudakis, Konstantinos Triantafyllidis
Summary: Mesoporous silicas with different structural properties were synthesized by varying the time intervals between the addition of different silica monomers. One sample exhibited an unusual isotherm with two hysteresis loops and high pore volume. The materials were characterized and used as adsorbents and release platforms for diclofenac sodium, revealing differences in adsorption and release behavior.
Article
Chemistry, Multidisciplinary
Lazaros Papadopoulos, Lorenzo Pezzana, Natalia Maria Malitowski, Marco Sangermano, Dimitrios. N. N. Bikiaris, Tobias Robert
Summary: In the search for sustainable thermosets, research has been conducted on various polymer classes, including epoxy, benzoxazines, acryl-/methacrylates, etc. Itaconic acid-based unsaturated polyester resins are a particular group that can also be used as sustainable inks for additive manufacturing. This study synthesized a series of itaconic acid-based polyesters with different reactive diluent contents and evaluated their physicochemical properties and reactivity toward UV light. The same formulations were used for 3D printing and their thermomechanical properties were examined.
Article
Pharmacology & Pharmacy
Xuezhi Zhuo, Vito Fodera, Per Larsson, Zarah Schaal, Christel A. S. Bergstrom, Korbinian Lobmann, Aleksei Kabedev
Summary: Our previous work demonstrated that beta-lactoglobulin-stabilized amorphous solid dispersion (ASD) loaded with 70 % indomethacin remains stable for over 12 months. We further investigated the stabilization mechanisms by testing five other drug molecules and using experimental techniques and molecular dynamics simulations. The results showed that steric confinement, hydrogen bonding, and the glass transition temperature of the drug molecule play important roles in stabilizing ASDs with high drug loadings.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Sebastian Schmidt, Ulrike Holzgrabe
Summary: The binding of drugs to plasma proteins, such as human serum albumin (HSA), is crucial for determining pharmacokinetic parameters. This study investigated the enantioselective binding of S- and R-ketamine to HSA. It was found that ketamine has weak affinity to HSA, with no significant differences in binding behavior between the individual enantiomers and the racemate. The aromatic ring and N-methyl group were identified as the most strongly involved structural moieties in the binding of ketamine to HSA.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Yuchen Zhao, Han Wang, Lin Jin, Ziwei Zhang, Lianghu Liu, Mengqi Zhou, Xianzheng Zhang, Lingling Zhang
Summary: Interleukins (ILs) are important for communication between immune cells and non-immune cells, but dysregulation of ILs expression is a characteristic of autoinflammatory diseases. Drugs targeting ILs have significant clinical benefits, but may also cause adverse reactions. Fusion protein technology, with its ability to enhance therapeutic efficacy, has been explored for developing anti-inflammatory drugs. This review discusses the efficacy of fusion protein drugs developed with ILs or their receptors in treating autoinflammatory diseases, highlighting the potential of this technology in future anti-inflammatory drug development.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Serena Bertoni, Elena Simone, Stefano Sangiorgi, Beatrice Albertini, Nadia Passerini
Summary: This study investigated the correlation between the structure and release properties of solid lipid microparticles (MPs) with different liquid additives. The additives accelerated the conversion of the unstable alpha-form of tristearin to the stable beta-polymorph and caused structural modifications in the MPs. The presence of additives prolonged the drug release in water and resulted in higher release profiles in biorelevant media. The findings suggest that the release behavior can be influenced by the polymorphism and supramolecular-level structural modification of lipid formulations containing crystal modifiers.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Juulia Jarvinen, Ahmed B. Montaser, Santosh Kumar Adla, Jukka Leppanen, Marko Lehtonen, Kati-Sisko Vellonen, Tuomo Laitinen, Aaro Jalkanen, William F. Elmquist, Juri Timonen, Kristiina M. Huttunen, Jarkko Rautio
Summary: This study attempted to alter the brain distribution pattern of Palbociclib by creating and assessing two novel prodrugs. Although the prodrug design did not significantly improve Palbociclib brain delivery, the study provides valuable insights for future prodrug development and drug delivery strategies targeting specific transporters.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Review
Pharmacology & Pharmacy
Miao Wang, Xinyu Ma, Shiyu Zong, Yaqiong Su, Rui Su, Hong Zhang, Yang Liu, Chunliu Wang, Ye Li
Summary: This article discusses the potential and limitations of nasal administration in central nervous system drug delivery. Nasal gel viscosity can alleviate the impact of nasal mucociliary clearance on drug delivery, and materials such as gellan gum, chitosan, carbomer, cellulose, and poloxamer can be used to prepare nasal gels.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Bjarke Strom Larsen, Eric Kissi, Liebert Parreiras Nogueira, Natalja Genina, Ingunn Tho
Summary: This study investigates the influence of drug load and polymer molecular weight on the structure of 3D printed tablets. The results show that drug load and polymer molecular weight have a significant impact on the porosity and size of the tablets, while the effect of drug load on the total porosity of the tablets is minimal.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Zhentao Qiao, Fuhang Wang, Dongjian Han, Yuansong Zhuang, Qingjiao Jiang, Yi Zhang, Miaomiao Liu, Quanxu An, Zhiwei Wang, Deliang Shen
Summary: In this study, it was demonstrated that periadventitial delivery of rapamycin-fibrin glue (RPM-FG) can inhibit intimal hyperplasia (IH) in a rat carotid artery injury model without compromising re-endothelialization. This provides a promising direction for the future development of a safe, effective, and minimally invasive perivascular drug delivery method to treat vascular disease.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
Article
Pharmacology & Pharmacy
Neele Puhlmann, Rodrigo Vidaurre, Klaus Kuemmerer
Summary: Active pharmaceutical ingredients and their metabolites and transformation products are pollutants that can harm human and environmental health. Designing greener APIs is an effective strategy to address this issue. The drug discovery and development process can incorporate environmental parameters to achieve this design, and this process is highly flexible.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2024)
