Article
Chemistry, Physical
Francisco de Azambuja, Jille Lenie, Tatjana N. Parac-Vogt
Summary: Inorganic clusters, specifically polyoxometalates (POMs), can serve as effective ligands for Hf(IV) Lewis acid metals in homogeneous metal catalysis. The interplay between the dielectric constant of the medium and the ligand structure is crucial for optimizing catalytic activity and promoting efficient amide bond formation. Changes in the dielectric constant can significantly impact the performance of the catalyst, highlighting the importance of understanding the relationship between medium properties and catalyst reactivity.
Article
Chemistry, Multidisciplinary
Kaixue Xie, Martin Oestreich
Summary: Readily available cyclohexa-2,5-dien-1-ylcarbonyl chloride derivatives were used as stable HCl surrogates for transfer hydrochlorination of alkenes and alkynes. B(C6F5)(3) facilitated the stepwise fragmentation of acyl chlorides, allowing the addition of HCl across C-C double and triple bonds with Markovnikov selectivity at room temperature.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Organic
Fanni Bede, Laszlo Kollar, Nandor Lambert, Peter Huszthy, Peter Pongracz
Summary: Palladium-catalyzed hydroaminocarbonylation reactions of olefins using aliphatic amines were successfully performed under carbon monoxide atmosphere. The targeted amides were synthesized in moderate to good isolated yields without the need for acidic additives. The effect of chiral diphosphines on product distribution, including chemo-, regio-, and enantioselectivities, was also investigated.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Damiano Cirri, Tiziano Marzo, Alessandro Pratesi
Summary: This article describes an unprecedented palladium/arsenic-based catalytic cycle for the hydration of nitriles to amides, which takes place under exceptionally mild conditions of neutral pH and moderate temperature (60°C). The versatility of this new catalytic cycle was tested on various nitriles, ranging from aliphatic to aromatic. The effect of ring substitution with electron withdrawing and electron donating groups, as well as potentially interferent functional groups such as hydroxy or pyridinic nitrogen, was investigated. Furthermore, a pilot study on the potential scalability of this approach for industrial production is presented, demonstrating its potential and rapid scale-up capability.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Applied
Shuichi Nakamura, Natsuki Matsumoto, Masato Kibe, Kazuki Abe, Tsunayoshi Takehara, Takeyuki Suzuki
Summary: This study reports the enantiodivergent reaction of ketimines derived from alpha-ketoesters with malononitriles using a single chiral source, resulting in the synthesis of various optically active compounds from the obtained malononitrile-derived alpha-amino acids. A proposed reaction mechanism explains the observed enantiodivergency in high yields with high enantioselectivities.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Biochemistry & Molecular Biology
Nuray Uzunlu, Peter Pongracz, Laszlo Kollar, Attila Takacs
Summary: In this research, bio-derived hemicellulose-based solvents, namely ethyl levulinate, methyl levulinate, and 2-methyltetrahydrofuran, were used as green alternatives in palladium-catalyzed aminocarbonylation reactions. Optimization reactions were conducted using iodobenzene and morpholine under varying conditions, including temperature, pressure, and ligands. The study found that the XantPhos ligand significantly influenced the conversion (98%) and chemoselectivity (100% carboxamide) compared to the monodentate PPh3 ligand. Furthermore, the optimized conditions were applied to expand the range of substrates and amine nucleophiles.
Article
Chemistry, Organic
Kellsie Jurkowski, Eike B. Bauer
Summary: Ferrocenium cations are used as catalysts in organic transformations, and their decomposition rate constants depend on the nature of the counterion, with oxidative process being the main decomposition pathway. The cosolvent and changes in counterions can influence the catalytic activity.
SYNTHESIS-STUTTGART
(2021)
Review
Chemistry, Multidisciplinary
Lionel Massi, Jean-Francois Gal, Elisabet Dunach
Summary: Metal triflates have demonstrated their applicability as catalysts in various organic reactions, primarily in C-O and C-C bond formation. Understanding the interaction between Lewis acids and organic functional groups as ligands helps in selecting suitable metal cations for specific reactions. Electrospray ionization mass spectrometry provides a means for characterizing and quantifying donor/acceptor interactions involved in catalytic processes. By using ligand displacement experiments, quantitative affinity scales of ligands towards metal centers can be established.
Article
Nanoscience & Nanotechnology
Adam Prekob, Gabor Muranszky, Milan Szori, Gabor Karacs, Ferenc Kristaly, Tibor Ferenczi, Bela Fiser, Bela Viskolcz, Laszlo Vanyorek
Summary: Carbon black-supported palladium-platinum catalysts were prepared with and without nickel(II) oxide or iron(III) oxide promoter materials using ultrasonic cavitation technology. The one-step catalyst preparation method without the need for post-treatments showed excellent catalytic activity in the hydrogenation of nitrobenzene, with no significant differences in selectivity and aniline yield observed even when promoters were present.
Article
Chemistry, Multidisciplinary
Taku Kitanosono, Tomoya Hisada, Yasuhiro Yamashita, Shu Kobayashi
Summary: Metal-bound water molecules have been recognized as a new aspect of soft Lewis acid catalysis. A chiral palladium aqua complex was constructed using a chiral ligand and hydrogen-bond donor, allowing efficient functionalization of carbon-hydrogen bonds of indoles in water. The use of aqueous environments enabled highly enantioselective reactions of sigma-indolylpalladium intermediates, presenting a potentially powerful approach for organometallic transformations under mild conditions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Cristiana Margarita, Davide Di Francesco, Helena Lundberg
Summary: Zirconocene triflate is a potent catalyst that can activate C-O bonds in carboxylic acids and alcohols without the need for water scavenging techniques. This article provides an overview of its use in direct amidation, esterification, and etherification reactions, as well as a discussion on the mechanistic aspects and catalyst class.
Article
Chemistry, Organic
Masahiro Abe, Sayasa Nitta, Erina Miura, Tetsutaro Kimachi, Kiyofumi Inamoto
Summary: Herein, we present a simple method for the synthesis of nitriles via base-promoted intramolecular nucleophilic aromatic substitution. This process eliminates the need for toxic cyanide species and transition metals, while maintaining redox-neutral conditions. Our method demonstrates excellent scope and compatibility with various functional groups, resulting in good to excellent yields of (hetero)aromatic nitriles.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Review
Chemistry, Inorganic & Nuclear
Erick Lopez, Sophie C. Thorp, Ram S. Mohan
Summary: Despite the limited availability, high cost, and toxicity of transition metal catalysts, they dominate the field of organic synthesis. In recent years, there has been increased interest in the use of catalysts derived from more readily available main group metals. Bismuth(III) compounds have gained popularity in organic synthesis due to their nontoxic nature, relatively low cost, and non-corrosive properties.
Article
Chemistry, Physical
Jacopo De Bellis, Michael Felderhoff, Ferdi Schuth
Summary: In this study, it was demonstrated that mixing multiple metal sources through ball milling can result in supported alloyed nanoparticles, expanding the method's application to the synthesis of supported bimetallic catalysts. The prepared Au-Pd and Au-Cu nanoparticles supported on MgO or YSZ were characterized using powder X-ray diffraction and electron microscopy, and their catalytic performance in CO oxidation was investigated to understand the impact of the synthetic method on the final catalyst materials.
CHEMISTRY OF MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Niklas Bormann, Jas S. Ward, Ann Kathrin Bergmann, Paula Wenz, Kari Rissanen, Yiwei Gong, Wolf-Benedikt Hatz, Alexander Burbaum, Florian F. Mulks
Summary: This study reports a scalable, convenient, and inexpensive synthesis of stable diiminium-based reagents and investigates their application in acylation reactions. The adducts formed by coordination with pyridine donors exhibit good Lewis acid properties, allowing efficient conversion of acyl esters to amides and imides.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Physical
Lotfi Sellaoui, Huabin Wang, Michael Badawi, Adrian Bonilla-Petriciolet, Zhuqi Chen
JOURNAL OF MOLECULAR LIQUIDS
(2020)
Article
Environmental Sciences
Jia Wang, Min Shen, Qing Gong, Xianghui Wang, Jiayi Cai, Songlin Wang, Zhuqi Chen
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Engineering, Environmental
Jawad Ali, Lei Wenli, Ajmal Shahzad, Jerosha Ifthikar, Gebremedhin G. Aregay, Irshad Ibran Shahib, Zouhair Elkhlifi, Zhulei Chen, Zhuqi Chen
Article
Engineering, Environmental
Jia Wang, Qing Gong, Jawad Ali, Min Shen, Jiayi Cai, Xinquan Zhou, Zhuwei Liao, Songlin Wang, Zhuqi Chen
CHEMICAL ENGINEERING JOURNAL
(2020)
Article
Engineering, Environmental
Ajmal Shahzad, Jawad Ali, Jerosha Ifthikar, Gebremedhin G. Aregay, Jingyi Zhu, Zhulei Chen, Zhuqi Chen
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Review
Neurosciences
Bhavesh D. Kevadiya, Jatin Machhi, Jonathan Herskovitz, Maxim D. Oleynikov, Wilson R. Blomberg, Neha Bajwa, Dhruvkumar Soni, Srijanee Das, Mahmudul Hasan, Milankumar Patel, Ahmed M. Senan, Santhi Gorantla, JoEllyn McMillan, Benson Edagwa, Robert Eisenberg, Channabasavaiah B. Gurumurthy, St Patrick M. Reid, Chamindie Punyadeera, Linda Chang, Howard E. Gendelman
Summary: The COVID-19 pandemic has affected more than 38 million people worldwide through person-to-person transmission of the SARS-CoV-2 virus. Effective treatment options have emerged in recent months, including repurposed antivirals, corticosteroids, and virus-specific antibodies. Complete viral eradication will require an effective, safe, and preventative vaccine.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Sicheng Zhang, Duane D. Miller, Wei Li
Summary: Vitamin D plays a crucial role in human health, not only in the musculoskeletal system but also in other areas. Deficiency of vitamin D is associated with various diseases, including osteoporosis, cardiovascular diseases, and cancer. More research is needed to assess the role of vitamin D in optimizing health and preventing diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Chemistry, Physical
Bhavesh D. Kevadiya, Jatin Machhi, Jonathan Herskovitz, Maxim D. Oleynikov, Wilson R. Blomberg, Neha Bajwa, Dhruvkumar Soni, Srijanee Das, Mahmudul Hasan, Milankumar Patel, Ahmed M. Senan, Santhi Gorantla, JoEllyn McMillan, Benson Edagwa, Robert Eisenberg, Channabasavaiah B. Gurumurthy, St Patrick M. Reid, Chamindie Punyadeera, Linda Chang, Howard E. Gendelman
Summary: The outbreak of SARS-CoV-2 causing COVID-19 has led to diverse and severe symptoms, making accurate diagnosis a key challenge. Rapid diagnosis and treatment measures are crucial in controlling the spread of the virus. The development of diagnostic tools, including nanomaterial-based ones, is essential in the fight against the pandemic.
Article
Chemistry, Multidisciplinary
Ahmed M. Senan, Binru Yin, Yaoyao Zhang, Mustapha M. Nasiru, Yong-Mei Lyu, Muhammad Umair, Javaid A. Bhat, Sicheng Zhang, Li Liu
Summary: This study introduces a novel catalytic method using Fe(III)-cit./Na2S2O8 catalyst for plant oils hydroxylation, producing hydroxy-fatty acids/esters. By adding oxidizing agents to Fe(III) in MeCN with H2O, a new complex of Fe(II)-species is generated, improving the C-H activation efficiency. CHML has potential applications in the food industry for food safety and packaging, with benefits for microbial resistance.
Review
Environmental Sciences
Zaid Ulhassan, Javaid Akhter Bhat, Weijun Zhou, Ahmed M. Senan, Pravej Alam, Parvaiz Ahmad
Summary: Excessive arsenic accumulation in plant tissues can have toxic impacts on growth and human health. Engineered nanoparticles (ENPs) have been found to reduce arsenic accumulation and toxicity, but the mechanisms are not fully understood.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Linda K. Myers, Michael Winstead, John D. Kee, Jeoungeun J. Park, Sicheng Zhang, Wei Li, Ae-Kyung Yi, John M. Stuart, Edward F. Rosloniec, David D. Brand, Robert C. Tuckey, Andrzej T. Slominski, Arnold E. Postlethwaite, Andrew H. Kang
Summary: Vitamin D plays a role in regulating inflammation, with the non-calcemic form 20S(OH)D3 showing promise as a potential therapeutic agent for autoimmune diseases like Rheumatoid Arthritis. These effects on inflammation are at least partly mediated by the natural inhibitory receptor LAIR-1.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Muhammad Umair, Tayyaba Sultana, Zhu Xiaoyu, Ahmed M. Senan, Saqib Jabbar, Labiba Khan, Muhammad Abid, Mian Anjum Murtaza, Dhama Kuldeep, Niyazi A. S. Al-Areqi, Lu Zhaoxin
Summary: This study investigated the antibacterial activities of vine tea against foodborne pathogens and found that one compound (C15H10O7) demonstrated strong antimicrobial activity against Bacillus cereus and Staphylococcus aureus.
FOOD SCIENCE & NUTRITION
(2022)
Article
Chemistry, Multidisciplinary
Niyazi A. S. Al-Areqi, Muhamad Umair, Ahmed M. Senan, Ahlam Al-Alas, Afraah M. A. Alfaatesh, Saba Beg, Kashif-ur-Rehman Khan, Sameh A. Korma, Mohamed T. El-Saadony, Mohammed A. Alshehri, Ahmed Ezzat Ahmed, Ahmed M. Abbas, Riyad A. Alokab, Ilaria Cacciotti
Summary: With the increasing demand for industrial dyes, water conditions have deteriorated, leading to increased attention on the removal of environmentally hazardous pollutants from wastewaters through photocatalytic degradation. This study synthesized three mesoporous nanophases of BiFeVOx.y as visible light photocatalysts and evaluated their photocatalytic activities in degrading organic dyes. The results showed that the synthesis methods and doping strategy played important roles in improving the structure and surface properties of the nanophases, enhancing their adsorption and photocatalytic efficiencies.
Article
Food Science & Technology
Mustapha Muhammad Nasiru, Evans Frimpong Boateng, Fawze Alnadari, Muhammad Umair, Zhaobin Wang, Ahmed M. Senan, Wenjing Yan, Hong Zhuang, Jianhao Zhang
Summary: This study investigated the effects of dielectric barrier discharge cold atmospheric plasma (DBD-CAP) treatment on the functional, rheological, and structural characteristics of egg white proteins (EWPs). The results showed that longer plasma treatment improved the solubility, foam and emulsion stabilities, and water and oil-holding capacities of EWPs. DBD-CAP also altered the secondary structure of EWPs, increasing alpha-helix, beta-sheets, and beta-turns, while decreasing random coils. These findings suggest that mild oxidation induced by plasma treatment enhances the attributes and structure of EWPs, potentially benefiting their utilization in the food industry.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Chemistry, Physical
Ahmed M. Senan, Muhammed Tilahun Muhammed, Laila A. Al-Shuraym, Sadeq K. Alhag, Niyazi A. S. Al-Areqi, Senem Akkoc
Summary: Phenyl ethanol derivatives are important drug molecules with potential anticancer activity. This study demonstrates an efficient catalytic conversion of alkynes to 1-phenyl ethanol derivatives, which could be a promising strategy for the development of anticancer agents.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
