Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)- N -phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors

标题
Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)- N -phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors
作者
关键词
Sirtuins, SIRT2, Epigenetics, Cancer, Structure-based optimization
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 134, Issue -, Pages 230-241
出版商
Elsevier BV
发表日期
2017-04-12
DOI
10.1016/j.ejmech.2017.04.010

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