Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC

标题
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC
作者
关键词
Epidermal growth factor receptor, Tyrosine kinase inhibitors, Non-small cell lung cancer, T790M, Mutant-selective
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 140, Issue -, Pages 510-527
出版商
Elsevier BV
发表日期
2017-09-21
DOI
10.1016/j.ejmech.2017.08.061

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