Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

(2016) Piotr Ponikowski et al.   EUROPEAN JOURNAL OF HEART FAILURE

2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure: An Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure

(2016) Clyde W. Yancy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Worsening heart failure during hospitalization for acute heart failure: Insights from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF)

(2015) Jacob P. Kelly et al.   AMERICAN HEART JOURNAL

Agents with vasodilator properties in acute heart failure: how to design successful trials

(2015) Alexandre Mebazaa et al.   EUROPEAN JOURNAL OF HEART FAILURE

Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial

(2015) Robert J. Mentz et al.   EUROPEAN JOURNAL OF HEART FAILURE

In-hospital worsening heart failure

(2015) Javed Butler et al.   EUROPEAN JOURNAL OF HEART FAILURE

Heart failure as a general pandemic in Asia

(2015) Hiroaki Shimokawa et al.   EUROPEAN JOURNAL OF HEART FAILURE

Serelaxin and acute heart failure

(2015) Jeremy Tietjens et al.   HEART

Worsening Heart Failure Following Admission for Acute Heart Failure

(2015) Beth A. Davison et al.   JACC-Heart Failure

Renal Hemodynamic Effects of Serelaxin in Patients With Chronic Heart Failure

(2014) Adriaan A. Voors et al.   Circulation-Heart Failure

Influence of Previous Heart Failure Hospitalization on Cardiovascular Events in Patients With Reduced and Preserved Ejection Fraction

(2014) Natalie A. Bello et al.   Circulation-Heart Failure

Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction

(2014) Søren L. Kristensen et al.   EUROPEAN JOURNAL OF HEART FAILURE

Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study

(2014) Gad Cotter et al.   EUROPEAN JOURNAL OF HEART FAILURE

Forecasting the Impact of Heart Failure in the United States

(2013) Paul A. Heidenreich et al.   Circulation-Heart Failure

Serelaxin in acute heart failure patients with preserved left ventricular ejection fraction: results from the RELAX-AHF trial

(2013) G. Filippatos et al.   EUROPEAN HEART JOURNAL

Risk following hospitalization in stable chronic systolic heart failure

(2013) Putte Abrahamsson et al.   EUROPEAN JOURNAL OF HEART FAILURE

2013 ACCF/AHA Guideline for the Management of Heart Failure

(2013) Clyde W. Yancy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Relaxin Family Peptides and Their Receptors

(2013) R. A. D. Bathgate et al.   PHYSIOLOGICAL REVIEWS

Effect of Levosimendan on the Short-Term Clinical Course of Patients With Acutely Decompensated Heart Failure

(2013) Milton Packer et al.   JACC-Heart Failure

The Causes, Treatment, and Outcome of Acute Heart Failure in 1006 Africans From 9 Countries

(2012) Albertino Damasceno et al.   ARCHIVES OF INTERNAL MEDICINE

Cinaciguat, a soluble guanylate cyclase activator, unloads the heart but also causes hypotension in acute decompensated heart failure†

(2012) Erland Erdmann et al.   EUROPEAN HEART JOURNAL

Effect of Serelaxin on Cardiac, Renal, and Hepatic Biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) Development Program

(2012) Marco Metra et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rehospitalization for Heart Failure

(2012) Mihai Gheorghiade et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

(2012) John R Teerlink et al.   LANCET

Dyspnoea and worsening heart failure in patients with acute heart failure: results from the Pre-RELAX-AHF study

(2010) Marco Metra et al.   EUROPEAN JOURNAL OF HEART FAILURE

Rolofylline, an Adenosine A1−Receptor Antagonist, in Acute Heart Failure

(2010) Barry M. Massie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Physician-Determined Worsening Heart Failure: A Novel Definition for Early Worsening Heart Failure in Patients Hospitalized for Acute Heart Failure – Association with Signs and Symptoms, Hospitalization Duration, and 60-Day Outcomes

(2009) Gad Cotter et al.   CARDIOLOGY

The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea study

(2009) A. Mebazaa et al.   EUROPEAN HEART JOURNAL

Early worsening heart failure in patients admitted with acute heart failure - a new outcome measure associated with long-term prognosis?

(2009) Beth Davison Weatherley et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Early Worsening Heart Failure in Patients Admitted for Acute Heart Failure: Time Course, Hemodynamic Predictors, and Outcome

(2009) Guillermo Torre-Amione et al.   JOURNAL OF CARDIAC FAILURE

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study

(2009) John R Teerlink et al.   LANCET

Cardiovascular effects of relaxin: from basic science to clinical therapy

(2009) Xiao-Jun Du et al.   Nature Reviews Cardiology

Incident Heart Failure Hospitalization and Subsequent Mortality in Chronic Heart Failure: A Propensity-Matched Study

(2008) Ali Ahmed et al.   JOURNAL OF CARDIAC FAILURE

A graphical approach to sequentially rejective multiple test procedures

(2008) Frank Bretz et al.   STATISTICS IN MEDICINE