Review
Nutrition & Dietetics
Hanna Dziewiecka, Harpal S. Buttar, Anna Kasperska, Joanna Ostapiuk-Karolczuk, Malgorzata Domagalska, Justyna Cichon, Anna Skarpanska-Stejnborn
Summary: This review examines the role of BC supplementation in improving gut permeability among athletes. The results suggest that BC supplementation may help reverse the increased gut permeability caused by vigorous exercise and could be highly beneficial in improving gut permeability in athletes. However, more well-designed studies are needed to evaluate the long-term safety and efficacy of BC supplementation and determine the optimal dosage schedules for high-performance athletes.
Article
Nutrition & Dietetics
Anna Skarpanska-Stejnborn, Miroslawa Cieslicka, Hanna Dziewiecka, Slawomir Kujawski, Anita Marcinkiewicz, Jerzy Trzeciak, Piotr Basta, Dariusz Maciejewski, Ewa Latour
Summary: The study examined the effects of long-term supplementation of bovine colostrum on the response of immune function during physical exercise testing in athletes, and found that the supplementation did not significantly affect the dynamics of immune system function indicators.
Article
Multidisciplinary Sciences
Charles K. Crawford, Veronica Lopez Cervantes, Mary L. Quilici, Anibal G. Armien, Maria Questa, Muhammad S. Matloob, Leon D. Huynh, Aeelin Beltran, Sophie J. Karchemskiy, Katti R. Crakes, Amir Kol
Summary: This study investigates the direct effects of three inflammatory cytokines (TNF alpha, IFN gamma, and IL-18) on the bovine intestinal barrier. The results show that TNF alpha and IFN gamma treatment lead to intestinal epithelial barrier dysfunction and alterations in tight junction morphology and cellular turnover.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Birna Asbjornsdottir, Alba Miranda-Ribera, Maria Fiorentino, Takumi Konno, Murat Cetinbas, Jinggang Lan, Ruslan I. I. Sadreyev, Larus S. S. Gudmundsson, Magnus Gottfredsson, Bertrand Lauth, Bryndis Eva Birgisdottir, Alessio Fasano
Summary: The microbiota-gut-brain axis involves bidirectional communication between intestinal microbiota and various systems in the body, such as the gastrointestinal tract, central nervous system, and neuroendocrine/neuroimmune systems. This study investigates the effects of bovine colostrum administration on the intestinal microbiota and behavior in two mouse models and suggests its potential use in prophylactic approaches in the future.
Article
Biochemistry & Molecular Biology
Zhenqi Liu, Alison B. Lansley, Tu Ngoc Duong, John D. Smart, Ananth S. Pannala
Summary: This study investigated the potential of novel polymer-surfactant-based formulations to improve the solubility and permeability of curcumin. The results showed that formulation A, containing Soluplus (R) and vitamin E TPGs, significantly increased the permeation and cellular uptake of curcumin compared to other samples.
Article
Agriculture, Dairy & Animal Science
Victoria Ortin-Piqueras, Tobias L. Freitag, Leif C. Andersson, Sanna H. Lehtonen, Seppo K. Meri, Thomas Spillmann, Rafael Frias
Summary: Intestinal permeability tests using iohexol in mouse models show that a 6 h cumulative urine sample may be sufficient to evaluate small intestinal permeability. Increased urinary excretion of iohexol is correlated with increased severity of duodenitis, suggesting potential as a marker for intestinal damage assessment. Reducing cage periods from 24 to 6 hours can improve animal welfare during these tests.
Article
Multidisciplinary Sciences
Ewa Sadowska-Krepa, Michal Rozpara, Adam Rzetecki, Sebastian Bankowski, Aleksandra Zebrowska, Wanda Pilch
Summary: This study found that a strenuous 12-hour run disrupts the prooxidant-antioxidant balance in middle-aged men, promotes inflammation, and impairs intestinal permeability.
Article
Food Science & Technology
Anne Vuholm Sunds, Apichaya Bunyatratchata, Randall Robinson, Maria Glantz, Marie Paulsson, Daiva Leskauskaite, Anne Pihlanto, Ragnhild Inglingstad, Tove G. Devold, Gerd E. Vegarud, Bryndis Eva Birgisdottir, Maria Gudjonsdottir, Daniela Barile, Lotte Bach Larsen, Nina Aagaard Poulsen
Summary: This study characterized milk oligosaccharides from native North European cattle breeds for the first time, identifying various monosaccharide compositions and isomers. Western Finncattle milk had the highest abundance of oligosaccharides, Eastern Finncattle milk had higher levels of acidic oligosaccharides, and Icelandic cattle milk had higher levels of fucosylated oligosaccharides.
INTERNATIONAL DAIRY JOURNAL
(2021)
Article
Nutrition & Dietetics
Miroslawa Cieslicka, Joanna Ostapiuk-Karolczuk, Harpal S. Buttar, Hanna Dziewiecka, Anna Kasperska, Anna Skarpanska-Stejnborn
Summary: The study aimed to evaluate the effects of 6-month bovine colostrum supplementation on oxidative stress level, inflammation, and iron metabolism biomarkers in highly trained female athletes. The results showed that bovine colostrum supplementation significantly reduced TBARS level and increased IL-6, SOD activity, transferrin, and lactoferrin levels. These findings suggest that bovine colostrum supplementation can reduce harmful effects of free radicals, oxidative stress, and inflammation, and positively affect iron homeostasis in female athletes.
Article
Agriculture, Dairy & Animal Science
Guadalupe Ceja, Jacquelyn P. Boerman, Rafael C. Neves, Nicholas S. Johnson, Jon P. Schoonmaker, Matthew W. Jorgensen, Jay S. Johnson
Summary: Urethral catheterization can be used to evaluate gastrointestinal tract permeability in 1- and 6-wk-old Holstein heifer calves, providing valuable information for treatment and mitigation strategies.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Multidisciplinary Sciences
Stephanie Kung, Michael N. Vakula, Youngwook Kim, Derek L. England, Janet Bergeson, Eadric Bressel, Michael Lefevre, Robert Ward
Summary: The study aimed to investigate the effects of supplemental flavonoid intake on intestinal health and cycling performance. The results showed that the intake of flavonoids did not alleviate exercise-induced intestinal injury during submaximal cycling.
Article
Pharmacology & Pharmacy
Frederic Moens, Gies Vandevijver, Anke De Blaiser, Adam Larsson, Fabio Spreafico, Patrick Augustijns, Massimo Marzorati
Summary: This study developed the Diamod(R) model as a dynamic gastrointestinal transfer model with physically interconnected permeation, and validated its accuracy in simulating the impact of intraluminal dilution and negative food effect on drug exposure. The Diamod(R) accurately simulated the impact of water intake on the gastrointestinal behavior of itraconazole solution and the negative food effect for indinavir sulfate, providing a useful in vitro model for studying drug performance in the gastrointestinal tract.
INTERNATIONAL JOURNAL OF PHARMACEUTICS-X
(2023)
Article
Agriculture, Dairy & Animal Science
B. S. Henrichs, K. N. Brost, C. A. Hayes, J. M. Campbell, J. K. Drackley
Summary: The study aimed to determine the effects of increasing SDP inclusion in MR on growth and health of calves fed at a high plane of nutrition. Results indicated that SDP can be included at up to 10% with improvements in average daily gain. Additionally, a 1:1 SDP plus wheat protein blend can be used at 12% inclusion with no difference in most health and growth parameters.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Maria Fernanda Roca Rubio, Ulrika Eriksson, Robert J. Brummer, Julia Konig
Summary: This study investigated the effect of sauna-induced dehydration on intestinal barrier function and found that sauna dehydration increased intestinal permeability without substantial damage to enterocytes. Additionally, it led to changes in inflammatory markers.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Da-Yeon Lee, Chan-Yang Lee, Jin-Na Shin, Jeong-Ho Oh, Soon-Mi Shim
Summary: The combination of soy lecithin, zinc oxide, and methylsulfonylmethane significantly increases the bioavailability of branched-chain amino acids in protein mixtures and enhances their intestinal transport. This suggests that the co-consumption of proteins equally consisting of plant and animal sources with these excipients could improve the health benefits associated with branched-chain amino acids.
Correction
Geriatrics & Gerontology
J. Dyer, G. Davison, S. M. Marcora, Alexis R. Mauger
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Sport Sciences
Henry B. Ogden, Joanne L. Fallowfield, Robert B. Child, Glen Davison, Simon C. Fleming, Simon K. Delves, Alison Millyard, Caroline S. Westwood, Joseph D. Layden
Summary: The study found that acute low-dose glutamine (GLN) supplementation may worsen intestinal permeability before high-intensity exertional-heat stress, but does not influence small intestinal epithelial injury or microbial translocation.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Jorge Berlanga-Acosta, Maday Fernandez-Mayola, Yssel Mendoza-Mari, Ariana Garcia-Ojalvo, Indira Martinez-Jimenez, Nadia Rodriguez-Rodriguez, Raymond J. Playford, Osvaldo Reyes-Acosta, Laura Lopez-Marin, Gerardo Guillen-Nieto
Summary: Lower-extremity arterial disease is a serious health issue that can lead to amputation, disability, and death. This study suggests the existence of a vascular tissue memory that can be transferred from humans to animals, causing arterial wall thickening and other vascular pathologies. The researchers found that the infiltration of arteriosclerotic tissue homogenates into rats resulted in significant thickening of arteriolar walls and other vascular changes. These findings may contribute to a better understanding of atherosclerosis pathobiology.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Hospitality, Leisure, Sport & Tourism
Eleanor Perkins, Glen Davison
Summary: The study investigated the relationship between salivary EBV DNA and URS in professional football players, finding that salivary IgA is a useful marker for URS risk but EBV DNA is not. Further research is needed to fully determine the utility of these markers in predicting URS episodes.
RESEARCH QUARTERLY FOR EXERCISE AND SPORT
(2022)
Meeting Abstract
Oncology
C. Harper-Wynne, J. L. Glendenning, G. Davison
ANNALS OF ONCOLOGY
(2022)
Review
Nutrition & Dietetics
Daniel S. March, Thomas J. Wilkinson, Thomas Burnell, Roseanne E. Billany, Katherine Jackson, Luke A. Baker, Amal Thomas, Katherine A. Robinson, Emma L. Watson, Matthew P. M. Graham-Brown, Arwel W. Jones, James O. Burton
Summary: This study systematically reviewed the effects of interventions on outcome measures associated with sarcopenia in end-stage kidney disease (ESKD). The findings suggest that intradialytic exercise can increase hand grip strength and sit-to-stand test performance, while L-carnitine and nandrolone-decanoate show potential for increasing muscle mass in the dialysis population.
Article
Medicine, General & Internal
Anne E. Holland, Arwel W. Jones, Ajay Mahal, Natasha A. Lannin, Narelle Cox, Graham Hepworth, Paul O'Halloran, Christine F. McDonald
Summary: This study aims to examine the effects of offering patients a choice of pulmonary rehabilitation locations (home or centre) compared with offering only the traditional centre-based model. It is a two-arm cluster randomised trial where participants with COPD will be recruited and allocated to intervention or control groups. The primary outcome is unplanned hospitalisations in the 12 months following rehabilitation.
Article
Microbiology
Matthew J. W. Furber, Gregory R. Young, Giles S. Holt, Simone Pyle, Glen Davison, Michael G. Roberts, Justin D. Roberts, Glyn Howatson, Darren L. Smith
Summary: This study investigated the impact of high-protein or high-carbohydrate diets on endurance performance and gut microbial communities. It found that high-carbohydrate diets improved performance, while high-protein diets reduced performance. The gut phageome, specifically bacteriophage communities, were most affected by dietary manipulation. Stable gut microbial communities were associated with better athletic performance.
Article
Physiology
Sarah Chantler, Alex Griffiths, Padraic Phibbs, Gregory Roe, Carlos Ramirez-Lopez, Glen Davison, Ben Jones, Kevin Deighton
Summary: The study aimed to assess the impact of rugby training on intestinal endothelial cell damage and permeability in academy rugby players. The results showed that rugby training led to increased intestinal endothelial cell damage and permeability, and this effect persisted after six weeks of preseason training.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Review
Respiratory System
Anne E. Holland, Bruna Wageck, Mariana Hoffman, Annemarie L. Lee, Arwel W. Jones
Summary: In this study, it was found that pulmonary rehabilitation programs mainly address deconditioning but pay less attention to other treatable traits. Treating multiple treatable traits did not show significant differences in exercise capacity and health-related quality of life outcomes.
EUROPEAN RESPIRATORY REVIEW
(2022)
Editorial Material
Environmental Sciences
Glen Davison
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Editorial Material
Nutrition & Dietetics
David C. Nieman, Glen Davison, Vassilis Mougios, Laurel M. Wentz
FRONTIERS IN NUTRITION
(2023)
Article
Clinical Neurology
Anna Ferrusola-Pastrana, Glen Davison, Stephen N. Meadows
Summary: A weekly community-based multimodal exercise program can improve and maintain physical and cognitive function in individuals with Parkinson's Disease. The program showed significant improvements in walking capacity, functional mobility, lower extremity strength, grip strength, cognition, and BDNF levels.
PARKINSONISM & RELATED DISORDERS
(2023)
Article
Nutrition & Dietetics
Arwel W. Jones, Adrian Mironas, Luis A. J. Mur, Manfred Beckmann, Rhys Thatcher, Glen Davison
Summary: The study aimed to investigate the effects of vitamin D status on exercise-induced immune dysfunction. The results showed that deficiency in vitamin D led to a decrease in lymphocyte count and an increase in neutrophil:lymphocyte ratio. It also affected metabolomic profiles, including purine/pyrimidine catabolites, inflammatory markers, lactate, and tyrosine/adrenaline.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Review
Respiratory System
Joanna Y. T. Lee, Gabriella Tikellis, Leona Dowman, Arwel W. Jones, Mariana Hoffman, Christie R. Mellerick, Carla Malaguti, Yet H. Khor, Anne E. Holland
Summary: This review examined the common self-management components, outcome measures, and impact in individuals with pulmonary fibrosis (PF). The results showed that education, symptom management, and psychosocial well-being were common self-management components. These components were predominantly delivered in pulmonary rehabilitation settings and no studies tested PF-specific self-management packages.
EUROPEAN RESPIRATORY REVIEW
(2023)