Article
Environmental Sciences
Shaojing Sun, Qing Wang, Na Wang, Shengjuan Yang, Hong Qi
Summary: Antibiotic resistance genes (ARGs) and antibiotics were found to be more abundant in human dominated ecosystems, particularly in urban wastewater. This study assessed the distribution of ARGs and antibiotics in Northeast China's urban wastewater, including domestic, livestock, hospital, pharmaceutical wastewater, and influent of the wastewater treatment plant (WWTP). ARGs were most abundant in community wastewater, followed by WWTP influent, livestock wastewater, pharmaceutical wastewater, and hospital wastewater. The dominant ARG subtypes varied among the different ecotypes. The concentration of antibiotics was closely related to antibiotic usage and consumption data. The correlation between ARGs and their corresponding antibiotics was ambiguous, but high ecotoxic antibiotics were positively correlated with ARGs and class 1 integrons (intI1). This suggests that ecotoxic compounds may contribute to antimicrobial resistance through horizontal gene transfer of ARGs. Further research is needed to study the coupling mechanism between the ecological risk of antibiotics and bacterial resistance, providing new insights into the impact of environmental pollutants on ARGs in different ecotypes.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Environmental Sciences
Hannah C. Lepper, Meghan R. Perry, Bryan A. Wee, David Wills, Hanne Nielsen, Saria Otani, Moray Simon, Frank M. Aarestrup, Mark E. J. Woolhouse, Bram A. D. van Bunnik
Summary: This study compares the resistome and microbiome of hospital, community, and mixed municipal wastewater and finds that the resistome in hospital wastewater is different from that in other locations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Zamazwi Lukhanyiso Mthiyane, Nkosinathi Makhubela, Hlengilizwe Nyoni, Lawrence Mzukisi Madikizela, Bethusile Rejoice Maseko, Somandla Ncube
Summary: This study investigated the removal of 15 selected antibiotics in African wastewater treatment plants and found that traditional treatment methods were less effective. The sedimentation stage showed positive removal efficiencies for most antibiotics, while negative removal efficiencies were observed in the aeration stage. Overall, only 4 antibiotics had removal efficiencies above 50%.
ENVIRONMENTAL TECHNOLOGY
(2023)
Article
Microbiology
Jose F. Delgado-Blas, Cecilia Valenzuela Agui, Elena Marin Rodriguez, Carlos Serna, Natalia Montero, Courage Kosi Setsoafia Saba, Bruno Gonzalez-Zorn
Summary: Wastewater plays a significant role in antimicrobial resistance (AMR) dynamics and public health. This study analyzed the epidemiological scenario of AMR in wastewater around the Tamale metropolitan area in Ghana, and found that hospital wastewater serves as a hotspot for the emergence and spread of AMR genes and bacteria.
Article
Microbiology
Dengwei Zhang, Ye Peng, Chak-Lun Chan, Hilda On, Hogan Kok-Fung Wai, Sandeep Singh Shekhawat, Akhilendra Bhushan Gupta, Alok Kumar Varshney, Rungtip Chuanchuen, Xudong Zhou, Yankai Xia, Suisha Liang, Keiji Fukuda, Krishna Mohan Medicherla, Hein M. Tun
Summary: Our study in Jaipur City, India, found lower abundance of ARGs in a hospital wastewater treatment plant compared to municipal wastewater treatment plants, which showed enrichment of tetracycline and macrolide-lincosamide-streptogramin resistance genes. Hospital wastewater had a higher abundance of genes conferring resistance to disinfectant-related compounds. Additionally, a strong correlation was found between the numbers of ARGs and BMRGs potentially harbored by common hosts in wastewater systems with more chemicals.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Environmental Sciences
Omuferen-oke Loveth Oharisi, Somandla Ncube, Hlengilizwe Nyoni, Mzukisi Lawrence Madikizela, Oluwole Joshua Olowoyo, Bethusile Rejoice Maseko
Summary: The increased usage of antibiotics has raised concerns about their presence in wastewater worldwide. This study investigated the occurrence of 16 selected antibiotics in wastewater treatment plants and rivers in Pretoria, South Africa. The results showed that antibiotics were present in both influent and effluent samples, with concentrations ranging from 0.12 to 9.89 ng mL-1. The presence of antibiotics in the rivers indicated that there were other sources of contamination besides the treatment plants. The study concluded that wastewater treatment plants were releasing antibiotics into the environment, posing risks to the aquatic ecosystem and public health.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Engineering, Chemical
Jiahuan Li, Xiao Qiu, Shaojie Ren, Hao Liu, Shan Zhao, Zhonghua Tong, Yunkun Wang
Summary: A series of poly-aniline/carbon nanotube-assisted electroactive membranes (PANI/CNT-EMs) were fabricated to remove low-concentration antibiotics, antibiotic-resistant bacteria, and antibiotic resistance genes in wastewater effluent, reducing ecotoxicity and antibiotic resistance pollution.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Microbiology
Maitreyee Mukherjee, Edward Laird, Terry J. Gentry, John P. Brooks, Raghupathy Karthikeyan
Summary: This study revealed wastewater treatment plants as hotspots for the spread of antimicrobial resistance (AMR) and multidrug resistance (MDR), with downstream locations showing significantly higher concentrations of antibiotic-resistant heterotrophs and antibiotic resistance genes (ARGs) compared to upstream sites. The findings support the need for improved environmental regulations and practices to manage AMR/MDR and ARG discharges into the environment.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Agricultural Engineering
Heshan Zheng, Yunfei Zhang, Shuo Li, Xiaochi Feng, Qinglian Wu, Yoong Kit Leong, Jo-Shu Chang
Summary: This study analyzed the ecotoxicity and induction capacity of antibiotic resistance genes (ARGs) in sulfadiazine degradation intermediates resulting from persulfate activation oxidation enhanced by ultraviolet, ultrasound, and microwave. The five degradation pathways and variations in the ecotoxicity of different degradation products were analyzed. Microcosm experiment revealed significant changes in the microbial community in actual water with sulfadiazine and degradation intermediates, and certain ARGs were induced more strongly by the intermediates than by sulfadiazine itself. Network analysis showed potential hosts for sulfonamide ARGs. These findings contribute to a better understanding of antibiotics degradation mechanism and controlling the spread of ARGs.
BIORESOURCE TECHNOLOGY
(2023)
Article
Environmental Sciences
Heshan Zheng, Yitong Ji, Shuo Li, Wei Li, Junfeng Niu
Summary: Studying the ecological risks of antibiotics and their degradation products is important for water environment security and AOPs development. This study found that tetracycline (TC) exhibited differential degradation pathways and resulted in differential growth inhibition trends on determined strains under different free radicals. Microcosm experiments combined with metagenomics revealed significant changes in the microbial community and TC resistance genes in water environment. Additionally, the study investigated the richness of genes related to oxidative stress and their effect on reactive oxygen species production and SOS response caused by TC and its intermediates.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Zeren Beril Gonder, Emel Mataraci Kara, Berna Ozbek Celik, Ilda Vergili, Yasemin Kaya, Serdar Mehmet Altinkum, Yasar Bagdatli, Gulsum Yilmaz
Summary: This study investigated the presence of various classes of micro-pollutants in hospital wastewater in Istanbul, Turkey, as well as antibiotic resistance. The research found significant variations in the concentrations of different pharmaceutical active compounds in wastewater, and observed notable differences in antibiotic resistance rates between seasons.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Engineering, Environmental
Huiqun Zhang, Haoting Quan, Shiliu Song, Lianpeng Sun, Hui Lu
Summary: This study examined the toxicity and environmental risk associated with sulfamethoxazole (SMX) biodegradation in the sulfur-mediated biological process. The results showed that SMX can be effectively biodegraded in the sulfur-mediated biological wastewater system, reducing its toxicity and environmental risk. Additionally, the sulfur-mediated biological system exhibited resistance mechanisms, such as efflux pump and inactivation, to protect against SMX stress.
Article
Environmental Sciences
Ana Puljko, Svjetlana Dekic Rozman, Ivan Barisic, Ana Maravic, Marko Jelic, Ivana Babic, Milena Milakovic, Ines Petric, Nikolina Udikovic-Kolic
Summary: The study aimed to quantify enteric opportunistic pathogens (EOPs), resistance genes, and isolate enterobacterial strains from hospital wastewater. The results revealed high levels of ESBL and carbapenemase-producing Enterobacterales (CPE) isolates, all of which were multidrug-resistant. Therefore, effective pretreatment of hospital wastewater is necessary to prevent the transmission of clinically important pathogens and resistance genes.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Weiwei Li, Zhongjun Yang, Jiamin Hu, Bianfang Wang, Hao Rong, Ziyun Li, Yuqing Sun, Yunkun Wang, Xuhua Zhang, Mingyu Wang, Hai Xu
Summary: This study investigated the extent of resistance to 'last-resort' antibiotics in hospital wastewater. The findings revealed high levels of resistance and prevalent multiple resistance to antibiotics, including 'last-resort' antibiotics. The study also discovered inconsistencies between resistance phenotypes and genotypes, as well as the first occurrence of tet(X4)-containing tigecycline-resistant Gram-positive pathogens. Furthermore, the wastewater treatment processes were effective in preventing the release of 'last -resort' antibiotic resistant pathogens.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Microbiology
Danyan Qiu, Nuohan Xu, Qi Zhang, Wenya Zhou, Yan Wang, Zhenyan Zhang, Yitian Yu, Tao Lu, Liwei Sun, Ning-Yi Zhou, W. J. G. M. Peijnenburg, Haifeng Qian
Summary: This study assessed the effects of abamectin on soil microorganisms by treating plant-soil microcosms with abamectin at concentrations of 0.1 and 1.0 mg/kg. The results showed that although abamectin was degradable, it altered soil microbial communities, disrupted microbial interactions, and decreased community complexity and stability. At the higher concentration, opportunistic human diseases and soil-borne pathogens were enriched in the soil. However, most ecological functions in the soil recovered within 21 days after abamectin treatment.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Environmental Sciences
Delphine Lachassagne, Marilyne Soubrand, Magali Casellas, Adriana Gonzalez-Ospina, Christophe Dagot
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2015)
Article
Environmental Sciences
Jie Wang, Junfeng Wan, Haisong Li, Hongli Li, Christophe Dagot, Yan Wang
ENVIRONMENTAL TECHNOLOGY
(2017)
Article
Infectious Diseases
Pierrette Landrie Simo Tchuinte, Thibault Stalder, Silvia Venditti, Antoinette Ngandjio, Christophe Dagot, Marie-Cecile Ploy, Olivier Barraud
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2016)
Article
Engineering, Environmental
Maryse Michele Um, Olivier Barraud, Monique Kerouredan, Margaux Gaschet, Thibault Stalder, Eric Oswald, Christophe Dagot, Marie-Cecile Ploy, Hubert Brugere, Delphine Bibbal
Article
Environmental Sciences
Teofana Chonova, Vivien Lecomte, Jean-Luc Bertrand-Krajewski, Agnes Bouchez, Jerome Labanowski, Christophe Dagot, Yves Levi, Yves Perrodin, Laure Wiest, Adriana Gonzalez-Ospina, Benoit Cournoyer, Christel Sebastian
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2018)
Article
Environmental Sciences
Elodie Aubertheau, Thibault Stalder, Leslie Mondamert, Marie-Cecile Ploy, Christophe Dagot, Jerome Labanowski
SCIENCE OF THE TOTAL ENVIRONMENT
(2017)
Article
Engineering, Environmental
J. N. Louvet, C. Carrion, T. Stalder, M. Alrhmoun, M. Casellas, O. Potier, M. N. Pons, C. Dagot
Article
Environmental Sciences
Yue Yin, Junfeng Wan, Shaozhen Li, Hongli Li, Christophe Dagot, Yan Wang
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Environmental Sciences
J. N. Louvet, B. Homeky, M. Casellas, M. N. Pons, C. Dagot
Article
Ecology
Thibault Stalder, Olivier Barraud, Thomas Jove, Magali Casellas, Margaux Gaschet, Christophe Dagot, Marie-Cecile Ploy
Article
Engineering, Environmental
Junfeng Wan, Stephane Simon, Veronique Deluchat, Marie-Christine Dictor, Christophe Dagot
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING
(2013)
Article
Engineering, Environmental
Mousaab Alrhmoun, Claire Carrion, Magali Casellas, Christophe Dagot
WATER SCIENCE AND TECHNOLOGY
(2014)
Article
Environmental Sciences
Jie Wang, Junfeng Wan, Zihao Wu, Hongli Li, Haisong Li, Christophe Dagot, Yan Wang
Article
Agricultural Engineering
Qing Liu, Junfeng Wan, Jie Wang, Shunyi Li, Christophe Dagot, Yan Wang
BIORESOURCE TECHNOLOGY
(2017)