4.7 Review

Distribution of polybrominated diphenyl ethers in breast milk, cord blood and placentas: a systematic review

期刊

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 24, 期 27, 页码 21548-21573

出版社

SPRINGER HEIDELBERG
DOI: 10.1007/s11356-017-9821-8

关键词

PBDEs; Breast milk; Cord blood; Placenta; Infants; e-waste

资金

  1. Nature Science Research Project of Anhui Province [1408085MH192]
  2. Dr. Research Funds of Anhui Medical University [201201]

向作者/读者索取更多资源

Polybrominated diphenyl ethers (PBDEs) have been extensively used as flame retardants in consumer products. PBDEs rapidly bioaccumulate in the environment, food, wild animals and humans. In this review, we investigated the harmful effects of PBDEs on humans, especially in early life, and summarised the levels of PBDEs in human biological samples (breast milk, cord blood and placentas). In addition, we described the spatiotemporal distribution of PBDEs in this review. PBDE levels in breast milk, cord blood and placentas were generally higher in North America than in other regions, such as Asia, Europe, Oceania and Africa. However, high levels of PBDEs in human biological samples were detected at e-waste recycling sites in South China, East China and South Korea. This finding suggests that newborns living in e-waste regions are exposed to high levels of PBDEs during prenatal and postnatal periods. The time trends of PBDE concentration differed according to the region. Few studies have investigated PBDE levels in humans from 1967 to 2000, but they increased rapidly after 2000. PBDE concentration peaked at approximately 2006 globally. Compared with other PBDE congeners, BDE-47, BDE-153 and BDE-209 were the major components, but the detection rate of BDE-209 was lower than those of others. Future studies should focus on determining the BDE-209 concentration, which requires the implementation of different analytical approaches. Additionally, the levels of PBDEs in human samples and the environment should be monitored, especially in e-waste recycling regions.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Biophysics

Effects of diurnal temperature range on mortality in Hefei city, China

Jing Tang, Chang-chun Xiao, Yu-rong Li, Jun-qing Zhang, Hao-yuan Zhai, Ya Geng, Rui Ding, Jin-xia Zhai

INTERNATIONAL JOURNAL OF BIOMETEOROLOGY (2018)

Article Parasitology

Development of an empirical model to predict malaria outbreaks based on monthly case reports and climate variables in Hefei, China, 1990-2011

J. X. Zhai, Q. Lu, W. B. Hu, S. L. Tong, B. Wang, F. T. Yang, Z. W. Xu, S. P. Xun, X. H. Shen

ACTA TROPICA (2018)

Article Public, Environmental & Occupational Health

Association between air pollution and upper respiratory tract infection in hospital outpatients aged 0-14 years in Hefei, China: a time series study

Y. R. Li, C. C. Xiao, J. Li, J. Tang, X. Y. Geng, L. J. Cui, J. X. Zhai

PUBLIC HEALTH (2018)

Article Environmental Sciences

An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice

Jinxia Zhai, Xiya Geng, Tao Ding, Jun Li, Jing Tang, Daojun Chen, Longjiang Cui, Qizhi Wang

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2019)

Article Biophysics

Impact of ambient temperature on hospital admissions for cardiovascular disease in Hefei City, China

Longjiang Cui, Xiya Geng, Tao Ding, Jing Tang, Jixiang Xu, Jinxia Zhai

INTERNATIONAL JOURNAL OF BIOMETEOROLOGY (2019)

Article Environmental Sciences

Study on the association between ambient air pollution and daily cardiovascular death in Hefei, China

Jixiang Xu, Wenfeng Geng, Xiya Geng, LongJiang Cui, Tao Ding, Changchun Xiao, Junqing Zhang, Jing Tang, Jinxia Zhai

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020)

Article Environmental Sciences

Effects of perinatal exposure to endocrine-disrupting chemicals on the reproductive system of F3 generation male rodents: a meta-analysis

Huan He, Wenjing Chen, Yu Wei, Taifa Zhang, Wenfeng Geng, Jinxia Zhai

Summary: This study found a significant association between endocrine-disrupting chemicals and reproductive system damage in F3 generation male rodents, particularly affecting the testis, prostate, and kidney. However, it does not prove that EDCs are adverse factors for puberty abnormalities.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2022)

Article Pharmacology & Pharmacy

BDE-209 induce spermatocytes arrest at early-pachytene stage during meiotic prophase I in mice

Jinxia Zhai, Wenfeng Geng, Taifa Zhang, Yu Wei, Huan He, Wenjing Chen

Summary: This study found that BDE-209 has detrimental impacts on meiotic prophase I of spermatocytes in mice, including decreased sperm quality, increased oxidative stress and DNA damage, as well as impaired homologous recombination.

TOXICOLOGY (2022)

Article Environmental Sciences

Vitamin C supplementation rescued meiotic arrest of spermatocytes in Balb/c mice exposed to BDE-209

Taifa Zhang, Huan He, Yu Wei, Wenfeng Geng, Jinxia Zhai

Summary: This study investigated the protective effect of vitamin C on meiotic arrest induced by BDE-209 in spermatocytes and its mechanism. The results showed that vitamin C had a protective effect on male reproductive system by reducing testicular damage and abnormal sperm rate. Vitamin C also attenuated the oxidative stress response induced by BDE-209 and restored DNA repair and crossover markers necessary for meiotic division.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022)

Review Environmental Sciences

Do phthalates and their metabolites cause poor semen quality? A systematic review and meta-analysis of epidemiological studies on risk of decline in sperm quality

Houpeng Wang, Huan He, Yu Wei, Xin Gao, Taifa Zhang, Jinxia Zhai

Summary: A systematic review and meta-analysis showed a negative correlation between urine levels of MBP and MBzP, semen levels of DEHP, and semen concentration. However, no significant associations were found between MBP and MBzP with sperm motility and morphology, as well as between MEP, MMP, and MEHP with semen parameters.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2023)

Article Reproductive Biology

BDE-209 disturbed proliferation and differentiation of spermatogonia during mitotic process through estrogen receptor ?

Huan He, Tao Ding, Taifa Zhang, Wenfeng Geng, Jixiang Xu, Yu Wei, Jinxia Zhai

Summary: Deca-bromodiphenyl ether (BDE-209) exposure has been a public concern due to its negative impact on spermatogenesis and sperm quality. The study investigates the mechanism of BDE-209-induced dysfunction in mitosis, specifically the proliferation and differentiation of spermatogonia. The results indicate that BDE-209 exposure leads to a decline in sperm quality and disrupts the seminiferous tubule structure in rats. Furthermore, the study reveals that BDE-209 exposure impairs spermatogonia proliferation and differentiation through the downregulation of PLZF and cKit, as well as the alteration of ER alpha, Wnt3a, and Wnt5a expressions. The findings suggest that ER alpha plays a crucial role in the mitotic process of spermatogonia and provide potential therapeutic implications for improving sperm quality affected by BDE-209 exposure.

REPRODUCTIVE BIOLOGY (2023)

Review Engineering, Environmental

Environmental and occupational exposure to cadmium associated with male reproductive health risk: a systematic review and meta-analysis based on epidemiological evidence

Xin Gao, Guangying Li, Xingchen Pan, Jiajia Xia, Di Yan, Yang Xu, Xiang Ruan, Huan He, Yu Wei, Jinxia Zhai

Summary: There is inconclusive evidence regarding the correlation between cadmium exposure and adverse male reproductive health outcomes, despite the abundance of epidemiological evidence and animal experiments. A literature search was conducted to analyze Cd levels in different biological materials and its correlation with semen parameters and sex hormones. The results showed that Cd was negatively correlated with semen parameters and positively correlated with sex hormones, with blood and urine showing significant correlations in both cases. This suggests that cadmium exposure may be associated with a decline in sperm quality and abnormal levels of sex hormones.

ENVIRONMENTAL GEOCHEMISTRY AND HEALTH (2023)

Review Environmental Sciences

Polychlorinated biphenyls and risk of metabolic syndrome and comparison with the risk of diabetes: A systematic review and meta-analysis

Xin Gao, Di Yan, Guangying Li, Yu Wei, Huan He, Jinxia Zhai

Summary: This meta-analysis explored the relationship between polychlorinated biphenyls (PCBs) and metabolic syndrome (MetS). The results suggested that PCBs may not be a risk factor for MetS, but their high heterogeneity indicates that they are under-represented. Furthermore, total PCBs were found to be a protective factor against diabetes. Subgroup analysis revealed that different types and congerners of PCBs have varying effects on the risk of MetS and diabetes. Therefore, more high-quality research is needed to further understand the role of different species and congerners of PCBs in MetS and diabetes.

SCIENCE OF THE TOTAL ENVIRONMENT (2023)

Review Public, Environmental & Occupational Health

The association of environmental organochlorine pesticides exposure and human semen parameters: a systematic review and meta-analysis

Yang Xu, Yiqing Fan, Xin Gao, Xingchen Pan, Huan He, Jinxia Zhai

Summary: This study analyzed the relationship between environmental exposure to organochlorine pesticides (OCPs) and human semen parameters. The results showed that OCPs exposure was associated with a decrease in semen parameters, including sperm volume, sperm count, sperm concentration, sperm motility, and sperm morphology. Further actions are needed to protect male fertility in the future.

JOURNAL OF PUBLIC HEALTH-HEIDELBERG (2023)

Article Environmental Sciences

N-acetylcysteine rescues meiotic arrest during spermatogenesis in mice exposed to BDE-209

Yu Wei, Wenfeng Geng, Taifa Zhang, Huan He, Jinxia Zhai

Summary: This study aimed to evaluate the protective effects of N-acetylcysteine (NAC) on meiotic arrest in spermatocytes and decreased sperm quality in BDE-209-exposed mice. The results showed that pretreatment with NAC attenuated the oxidative stress status induced by BDE-209, improved testicular histology and sperm quality, and enhanced DNA damage repair. Therefore, NAC may have a protective effect against the spermatogenesis dysfunction caused by BDE-209.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2023)

暂无数据