Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs)

Identification of a sulfate metabolite of PCB 11 in human serum

(2017) Fabian A. Grimm et al.   ENVIRONMENT INTERNATIONAL

Induction of micronuclei and cell cycle arrest by some tri- and tetrachlorobiphenyls in mammalian cells deficient in xenobiotic-metabolizing enzymes

(2017) Haiyan Wang et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites

(2017) Eric Uwimana et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Absolute configuration of 2,2′,3,3′,6-pentachlorinatedbiphenyl (PCB 84) atropisomers

(2017) Xueshu Li et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Editor’s Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity

(2017) Izabela Kania-Korwel et al.   TOXICOLOGICAL SCIENCES

Detection of 3,3′-Dichlorobiphenyl in Human Maternal Plasma and Its Effects on Axonal and Dendritic Growth in Primary Rat Neurons

(2017) Sunjay Sethi et al.   TOXICOLOGICAL SCIENCES

Release of Airborne Polychlorinated Biphenyls from New Bedford Harbor Results in Elevated Concentrations in the Surrounding Air

(2017) Andres Martinez et al.   Environmental Science & Technology Letters

Potent mutagenicity of some non-planar tri- and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme

(2016) Yungang Liu et al.   ARCHIVES OF TOXICOLOGY

2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes

(2016) Eric Uwimana et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity

(2016) Gopi S. Gadupudi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

3D QSAR studies of hydroxylated polychlorinated biphenyls as potential xenoestrogens

(2016) Patricia Ruiz et al.   CHEMOSPHERE

Human CYP2E1-dependent mutagenicity of mono- and dichlorobiphenyls in Chinese hamster (V79)-derived cells

(2016) Chiteng Zhang et al.   CHEMOSPHERE

Sulfation of Lower Chlorinated Polychlorinated Biphenyls Increases Their Affinity for the Major Drug-Binding Sites of Human Serum Albumin

(2016) Eric A. Rodriguez et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effect of Pregnancy on the Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) Atropisomers and Their Hydroxylated Metabolites in Female Mice

(2015) Izabela Kania-Korwel et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Modulating inhibitors of transthyretin fibrillogenesis via sulfation: Polychlorinated biphenyl sulfates as models

(2015) Fabian A. Grimm et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Metabolism and metabolites of polychlorinated biphenyls

(2015) Fabian A. Grimm et al.   CRITICAL REVIEWS IN TOXICOLOGY

Parma consensus statement on metabolic disruptors

(2015) Jerrold J. Heindel et al.   Environmental Health

Inventory of PCBs in Chicago and Opportunities for Reduction in Airborne Emissions and Human Exposure

(2015) Caitlin E. Shanahan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Human Serum from Urban and Rural Adolescents and Their Mothers Shows Exposure to Polychlorinated Biphenyls Not Found in Commercial Mixtures

(2015) Wen Xin Koh et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tissue Distribution, Metabolism, and Excretion of 3,3′-Dichloro-4′-sulfooxy-biphenyl in the Rat

(2015) Fabian A. Grimm et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Use of mechanistic data in the IARC evaluations of the carcinogenicity of polychlorinated biphenyls and related compounds

(2015) Béatrice Lauby-Secretan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Identification of a novel hydroxylated metabolite of 2,2′,3,5′,6-pentachlorobiphenyl formed in whole poplar plants

(2015) Cunxian Ma et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Toxicokinetics of chiral polychlorinated biphenyls across different species—a review

(2015) Izabela Kania-Korwel et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Chiral polychlorinated biphenyls: absorption, metabolism and excretion—a review

(2015) Izabela Kania-Korwel et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

(2015) Gopi S. Gadupudi et al.   TOXICOLOGICAL SCIENCES

Detection and measurement of the agonistic activities of PCBs and mono-hydroxylated PCBs to the constitutive androstane receptor using a recombinant yeast assay

(2015) Ryo Kamata et al.   TOXICOLOGY IN VITRO

PCB126 inhibits adipogenesis of human preadipocytes

(2015) Gopi Gadupudi et al.   TOXICOLOGY IN VITRO

Disposition of Phenolic and Sulfated Metabolites after Inhalation Exposure to 4-Chlorobiphenyl (PCB3) in Female Rats

(2014) Kiran Dhakal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Microsomal Oxidation of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Results in Species-Dependent Chiral Signatures of the Hydroxylated Metabolites

(2014) Xianai Wu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Variability in PCB and OH-PCB Serum Levels in Children and Their Mothers in Urban and Rural U.S. Communities

(2014) Rachel F. Marek et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Hepatic Metabolism Affects the Atropselective Disposition of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) in Mice

(2014) Xianai Wu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Occurrence and distribution of PCB metabolites in blood and their potential health effects in humans: a review

(2014) Natalia Quinete et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Predictors of serum polychlorinated biphenyl concentrations in Anniston residents

(2014) M. Pavuk et al.   SCIENCE OF THE TOTAL ENVIRONMENT

PCB 136 Atropselectively Alters Morphometric and Functional Parameters of Neuronal Connectivity in Cultured Rat Hippocampal Neurons via Ryanodine Receptor-Dependent Mechanisms

(2014) Dongren Yang et al.   TOXICOLOGICAL SCIENCES

Chlorinated Biphenyl Quinones and Phenyl-2,5-benzoquinone Differentially Modify the Catalytic Activity of Human Hydroxysteroid Sulfotransferase hSULT2A1

(2013) Xiaoyan Qin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Sulfate Conjugates Are Urinary Markers of Inhalation Exposure to 4-Chlorobiphenyl (PCB3)

(2013) Kiran Dhakal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidation of Polychlorinated Biphenyls by Liver Tissue Slices from Phenobarbital-Pretreated Mice Is Congener-Specific and Atropselective

(2013) Xianai Wu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Atropisomeric determination of chiral hydroxylated metabolites of polychlorinated biphenyls using HPLC-MS

(2013) Guangshu Zhai et al.   Chemistry Central Journal

Interactions of cytosolic sulfotransferases with xenobiotics

(2013) Margaret O. James et al.   DRUG METABOLISM REVIEWS

Body burden of metals and persistent organic pollutants among Inuit in the Canadian Arctic

(2013) Brian D. Laird et al.   ENVIRONMENT INTERNATIONAL

The fate of inhaled 14C-labeled PCB11 and its metabolites in vivo

(2013) Xin Hu et al.   ENVIRONMENT INTERNATIONAL

Sulfated Metabolites of Polychlorinated Biphenyls Are High-Affinity Ligands for the Thyroid Hormone Transport Protein Transthyretin

(2013) Fabian A. Grimm et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Stereoselective Formation of Mono- and Dihydroxylated Polychlorinated Biphenyls by Rat Cytochrome P450 2B1

(2013) Zhe Lu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inhibition of Cytochromes P450 and the Hydroxylation of 4-Monochlorobiphenyl in Whole Poplar

(2013) Guangshu Zhai et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

PCBs and OH-PCBs in Serum from Children and Mothers in Urban and Rural U.S. Communities

(2013) Rachel F. Marek et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Assessment of hydroxylated metabolites of polychlorinated biphenyls as potential xenoestrogens: a QSAR comparative analysis∗

(2013) P. Ruiz et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Metabolism of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent

(2013) Xianai Wu et al.   XENOBIOTICA

Environmental contamination and human exposure to dioxin-related compounds in e-waste recycling sites of developing countries

(2013) Nguyen Minh Tue et al.   Environmental Science-Processes & Impacts

Identification of Sulfated Metabolites of 4-Chlorobiphenyl (PCB3) in the Serum and Urine of Male Rats

(2012) Kiran Dhakal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Role of Environmental Chemicals in Diabetes and Obesity: A National Toxicology Program Workshop Review

(2012) Kristina A. Thayer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) and Its Hydroxylated Metabolites Are Enantiomerically Enriched in Female Mice

(2012) Izabela Kania-Korwel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Assigning atropisomer elution orders using atropisomerically enriched polychlorinated biphenyl fractions generated by microsomal metabolism

(2012) Izabela Kania-Korwel et al.   JOURNAL OF CHROMATOGRAPHY A

Absolute Configuration of Atropisomeric Polychlorinated Biphenyl 183 Enantiomerically Enriched in Human Samples

(2012) Mitsunobu Toda et al.   JOURNAL OF PHYSICAL CHEMISTRY A

2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Is Enantioselectively Oxidized to Hydroxylated Metabolites by Rat Liver Microsomes

(2011) Xianai Wu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure–Activity Relationships for Hydroxylated Polychlorinated Biphenyls As Inhibitors of the Sulfation of Dehydroepiandrosterone Catalyzed by Human Hydroxysteroid Sulfotransferase SULT2A1

(2011) Edugie J. Ekuase et al.   CHEMICAL RESEARCH IN TOXICOLOGY

New hydroxylated metabolites of 4-monochlorobiphenyl in whole poplar plants

(2011) Guangshu Zhai et al.   Chemistry Central Journal

Multivariate toxicity profiles and QSAR modeling of non-dioxin-like PCBs – An investigation of in vitro screening data from ultra-pure congeners

(2011) Mia Stenberg et al.   CHEMOSPHERE

Gas Chromatographic Analysis with Chiral Cyclodextrin Phases Reveals the Enantioselective Formation of Hydroxylated Polychlorinated Biphenyls by Rat Liver Microsomes

(2011) Izabela Kania-Korwel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Enantioselective Biotransformation of Chiral PCBs in Whole Poplar Plants

(2011) Guangshu Zhai et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

PCB-induced changes of a benthic community and expected ecosystem recovery following in situ sorbent amendment

(2011) Elisabeth M.-L. Janssen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Evaluation of EPA’s Tier 1 Endocrine Screening Battery and recommendations for improving the interpretation of screening results

(2011) Christopher J. Borgert et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Dietary Selenium as a Modulator of PCB 126–Induced Hepatotoxicity in Male Sprague-Dawley Rats

(2011) Ian K. Lai et al.   TOXICOLOGICAL SCIENCES

In Vitro Toxicity Profiling of Ultrapure Non–Dioxin-like Polychlorinated Biphenyl Congeners and Their Relative Toxic Contribution to PCB Mixtures in Humans

(2011) Timo Hamers et al.   TOXICOLOGICAL SCIENCES

Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO2-PCBs

(2011) Elsa C. Antunes-Fernandes et al.   TOXICOLOGY LETTERS

Atmospheric PCB congeners across Chicago

(2010) Dingfei Hu et al.   ATMOSPHERIC ENVIRONMENT

Identification of hydroxylated metabolites of 3,3′,4,4′-tetrachlorobiphenyl and metabolic pathway in whole poplar plants

(2010) Guangshu Zhai et al.   CHEMOSPHERE

Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites

(2010) Wei Xie et al.   ENVIRONMENT INTERNATIONAL

Hydroxylated Metabolites of 4-Monochlorobiphenyl and Its Metabolic Pathway in Whole Poplar Plants

(2010) Guangshu Zhai et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

In Vitro Assay Shows That PCB Metabolites Completely Saturate Thyroid Hormone Transport Capacity in Blood of Wild Polar Bears (Ursus maritimus)

(2010) Arno C. Gutleb et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Fate of PCB Congeners in an Industrial Harbor of Lake Michigan†

(2010) Andres Martinez et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The Effect of Hydroxylated Polychlorinated Biphenyl (OH-PCB) on Thyroid Hormone Receptor (TR)-mediated Transcription through Native-Thyroid Hormone Response Element (TRE)

(2010) Izuki AMANO et al.   INDUSTRIAL HEALTH

Cytochrome P450-mediated metabolism in the human gut wall

(2010) Kirstin Thelen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Structure-Activity Relationships for Hydroxylated Polychlorinated Biphenyls as Substrates and Inhibitors of Rat Sulfotransferases and Modification of These Relationships by Changes in Thiol Status

(2009) Y. Liu et al.   DRUG METABOLISM AND DISPOSITION

Assessment of the disposition of chiral polychlorinated biphenyls in female mdr 1a/b knockout versus wild-type mice using multivariate analyses

(2009) Bartłomiej Milanowski et al.   ENVIRONMENT INTERNATIONAL

Polychlorinated biphenyls in the surficial sediment of Indiana Harbor and Ship Canal, Lake Michigan

(2009) Andres Martinez et al.   ENVIRONMENT INTERNATIONAL

Chiral Polychlorinated Biphenyl Transport, Metabolism, and Distribution: A Review†

(2009) Hans-Joachim Lehmler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Clearance of Polychlorinated Biphenyl Atropisomers is Enantioselective in Female C57Bl/6 Mice†

(2009) Izabela Kania-Korwel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inadvertent Polychlorinated Biphenyls in Commercial Paint Pigments†

(2009) Dingfei Hu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Spatial Distribution of Airborne Polychlorinated Biphenyls in Cleveland, Ohio and Chicago, Illinois†

(2009) Carolyn Persoon et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Hydroxylated PCB induces Ca2+oscillations and alterations of membrane potential in cultured cortical cells

(2009) Marina Londoño et al.   JOURNAL OF APPLIED TOXICOLOGY

Mono-hydroxylated polychlorinated biphenyls are potent aryl hydrocarbon receptor ligands in recombinant yeast cells

(2009) Ryo Kamata et al.   TOXICOLOGY IN VITRO

Enantiomeric Enrichment of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) in Mice After Induction of CYP Enzymes

(2008) Izabela Kania-Korwel et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Atropisomers Interact Enantioselectively with Hepatic Microsomal Cytochrome P450 Enzymes

(2008) Izabela Kania-Korwel et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Enantiomeric Specificity of (−)-2,2′,3,3′,6,6′-Hexachlorobiphenyl toward Ryanodine Receptor Types 1 and 2

(2008) Isaac N. Pessah et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidation of 4-Chlorobiphenyl Metabolites to Electrophilic Species by Prostaglandin H Synthase

(2008) Orarat Wangpradit et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Discovery of Non-Aroclor PCB (3,3′-Dichlorobiphenyl) in Chicago Air

(2008) Dingfei Hu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Chiral Polychlorinated Biphenyls Are Biotransformed Enantioselectively by Mammalian Cytochrome P-450 Isozymes to Form Hydroxylated Metabolites

(2008) Nicholas A. Warner et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Gas chromatographic separation of methoxylated polychlorinated biphenyl atropisomers

(2008) Izabela Kania-Korwel et al.   JOURNAL OF CHROMATOGRAPHY A

Prediction of the health effects of polychlorinated biphenyls (PCBs) and their metabolites using quantitative structure–activity relationship (QSAR)☆☆☆

(2008) P. Ruiz et al.   TOXICOLOGY LETTERS

Placental transfer of polychlorinated biphenyls, their hydroxylated metabolites and pentachlorophenol in pregnant women from eastern Slovakia

(2007) June-Soo Park et al.   CHEMOSPHERE

Metabolic activation of PCBs to carcinogens in vivo—A review

(2007) Gabriele Ludewig et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Influence of dietary fat on the enantioselective disposition of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) in female mice

(2007) I. Kania-Korwel et al.   FOOD AND CHEMICAL TOXICOLOGY