Outward-Open Model of Thyroid Hormone Transporter Monocarboxylate Transporter 8 Provides Novel Structural and Functional Insights

Few Amino Acid Exchanges Expand the Substrate Spectrum of Monocarboxylate Transporter 10*

(2016) Jörg Johannes et al.   MOLECULAR ENDOCRINOLOGY

Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity

(2015) Bethany Nancolas et al.   BIOCHEMICAL JOURNAL

Further Insights into the Allan-Herndon-Dudley Syndrome: Clinical and Functional Characterization of a Novel MCT8 Mutation

(2015) Christine M. Armour et al.   PLoS One

Atomic-level characterization of transport cycle thermodynamics in the glycerol-3-phosphate:phosphate antiporter

(2015) Mahmoud Moradi et al.   Nature Communications

YASARA View—molecular graphics for all devices—from smartphones to workstations

(2014) Elmar Krieger et al.   BIOINFORMATICS

Psychomotor Retardation Caused by a Defective Thyroid Hormone Transporter: Report of Two Families with Different MCT8 Mutations

(2014) Ahmet Anık et al.   Hormone Research in Paediatrics

Histidines in Potential Substrate Recognition Sites Affect Thyroid Hormone Transport by Monocarboxylate Transporter 8 (MCT8)

(2013) Doreen Braun et al.   ENDOCRINOLOGY

Importance of Cysteine Residues in the Thyroid Hormone Transporter MCT8

(2013) Elaine C. Lima de Souza et al.   ENDOCRINOLOGY

Importance of His192 in the Human Thyroid Hormone Transporter MCT8 for Substrate Recognition

(2013) Stefan Groeneweg et al.   ENDOCRINOLOGY

The Role of Arg445 and Asp498 in the Human Thyroid Hormone Transporter MCT8

(2013) Stefan Groeneweg et al.   ENDOCRINOLOGY

Mutations in MCT8 in Patients with Allan-Herndon-Dudley-Syndrome Affecting Its Cellular Distribution

(2013) Simone Kersseboom et al.   MOLECULAR ENDOCRINOLOGY

Evidence of Evolutionary Conservation of Function between the Thyroxine Transporter Oatp1c1 and Major Facilitator Superfamily Members

(2010) Daniel E. Westholm et al.   ENDOCRINOLOGY

Essential Molecular Determinants for Thyroid Hormone Transport and First Structural Implications for Monocarboxylate Transporter 8

(2010) Anita Kinne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetics and phenomics of thyroid hormone transport by MCT8

(2010) Edith C.H. Friesema et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Structure of a fucose transporter in an outward-open conformation

(2010) Shangyu Dang et al.   NATURE

Pelizaeus-Merzbacher-Like disease presentation of MCT8 mutated male subjects

(2009) Catherine Vaurs-Barrière et al.   ANNALS OF NEUROLOGY

Elevated serum triiodothyronine and intellectual and motor disability with paroxysmal dyskinesia caused by a monocarboxylate transporter 8 gene mutation

(2009) OLIVER FUCHS et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Pathophysiological Importance of Thyroid Hormone Transporters

(2009) Heike Heuer et al.   ENDOCRINOLOGY

Importance of Monocarboxylate Transporter 8 for the Blood-Brain Barrier-Dependent Availability of 3,5,3′-Triiodo-l-Thyronine

(2009) Ainhoa Ceballos et al.   ENDOCRINOLOGY

Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters

(2009) Wendy M van der Deure et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Surface translocation and tri-iodothyronine uptake of mutant MCT8 proteins are cell type-dependent

(2009) Anita Kinne et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8

(2009) Elmar Krieger et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Salt-bridge Dynamics Control Substrate-induced Conformational Change in the Membrane Transporter GlpT

(2008) Christopher J. Law et al.   JOURNAL OF MOLECULAR BIOLOGY

Effective Cellular Uptake and Efflux of Thyroid Hormone by Human Monocarboxylate Transporter 10

(2008) Edith C. H. Friesema et al.   MOLECULAR ENDOCRINOLOGY