11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice

Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation

(2016) Lynne E. Ramage et al.   Cell Metabolism

Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation

(2016) Xing Zeng et al.   GENES & DEVELOPMENT

Cold Exposure Partially Corrects Disturbances in Lipid Metabolism in a Male Mouse Model of Glucocorticoid Excess

(2015) Johanna C. van den Beukel et al.   ENDOCRINOLOGY

Glucocorticoids Transcriptionally Regulate miR-27b Expression Promoting Body Fat Accumulation Via Suppressing the Browning of White Adipose Tissue

(2014) Xiaocen Kong et al.   DIABETES

Effects of glucocorticoids on human brown adipocytes

(2014) Johanna L Barclay et al.   JOURNAL OF ENDOCRINOLOGY

Identification of Factor H–like Protein 1 as the Predominant Complement Regulator in Bruch’s Membrane: Implications for Age-Related Macular Degeneration

(2014) Simon J. Clark et al.   JOURNAL OF IMMUNOLOGY

11 -HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess

(2014) S. A. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits

(2014) Tharappel M Anil et al.   BMC Pharmacology & Toxicology

UCP1 mRNA does not produce heat

(2013) Jan Nedergaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors Still Improve Metabolic Phenotype in Male 11β-HSD1 Knockout Mice Suggesting Off-Target Mechanisms

(2013) Erika Harno et al.   ENDOCRINOLOGY

Regulation of Lipid Metabolism by Glucocorticoids and 11β-HSD1 in Skeletal Muscle

(2013) Stuart A. Morgan et al.   ENDOCRINOLOGY

11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects

(2013) Ana Tiganescu et al.   JOURNAL OF CLINICAL INVESTIGATION

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Fat cells directly sense temperature to activate thermogenesis

(2013) L. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential roles of 11β-HSD1 in regulating brown adipocyte function

(2012) Juan Liu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Glucocorticoids induce mitochondrial gene transcription in HepG2 cells

(2011) Anna-Maria G. Psarra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type diet

(2011) Guoping Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Adipogenic and lipolytic effects of chronic glucocorticoid exposure

(2010) Jonathan E. Campbell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Changed Metabolic World with Human Brown Adipose Tissue: Therapeutic Visions

(2010) Jan Nedergaard et al.   Cell Metabolism

Mitochondrial translocation of the glucocorticoid receptor in double-positive thymocytes correlates with their sensitivity to glucocorticoid-induced apoptosis

(2009) Gergely Talabér et al.   INTERNATIONAL IMMUNOLOGY

Dynamic regulation of mitochondrial function by glucocorticoids

(2009) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA