标题
Genetic Causes of Functional Adrenocortical Adenomas
作者
关键词
-
出版物
ENDOCRINE REVIEWS
Volume 38, Issue 6, Pages 516-537
出版商
The Endocrine Society
发表日期
2017-08-03
DOI
10.1210/er.2017-00189
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma
- (2017) Ute I. Scholl et al. JOURNAL OF CLINICAL INVESTIGATION
- Analysis of ARMC5 expression in human tissues
- (2017) Annabel Berthon et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Armc5 deletion causes developmental defects and compromises T-cell immune responses
- (2017) Yan Hu et al. Nature Communications
- The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes
- (2017) Vin-Cent Wu et al. Scientific Reports
- SFE/SFHTA/AFCE primary aldosteronism consensus: Introduction and handbook
- (2016) Laurence Amar et al. ANNALES D ENDOCRINOLOGIE
- GNAS mutations in adrenal aldosterone-producing adenomas [Rapid Communication]
- (2016) Yasuyo Nakajima et al. ENDOCRINE JOURNAL
- Genetics of primary hyperaldosteronism
- (2016) Ravi Kumar Dutta et al. ENDOCRINE-RELATED CANCER
- Cellular Pathophysiology of an Adrenal Adenoma-Associated Mutant of the Plasma Membrane Ca2+-ATPase ATP2B3
- (2016) Philipp Tauber et al. ENDOCRINOLOGY
- Double adrenocortical adenomas harboring independentKCNJ5andPRKACAsomatic mutations
- (2016) Kazutaka Nanba et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Molecular Heterogeneity in Aldosterone-Producing Adenomas
- (2016) Kazutaka Nanba et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Aldosterone-Producing Adenoma With a Somatic KCNJ5 Mutation Revealing APC-Dependent Familial Adenomatous Polyposis
- (2016) Julien Vouillarmet et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Clinical and Steroidogenic Characteristics of Aldosterone-Producing Adenomas With ATPase orCACNA1DGene Mutations
- (2016) Takumi Kitamoto et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- PRKACASomatic Mutations Are Rare Findings in Aldosterone-Producing Adenomas
- (2016) Yara Rhayem et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism
- (2016) Koshiro Nishimoto et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas WithoutPRKACAp.Leu206Arg Mutation
- (2016) Cristina L. Ronchi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline
- (2016) John W. Funder et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Pregnancy, Primary Aldosteronism, and Somatic CTNNB1 Mutations
- (2016) NEW ENGLAND JOURNAL OF MEDICINE
- Immunohistochemistry of the adrenal in primary aldosteronism
- (2016) Celso E. Gomez-Sanchez et al. Current Opinion in Endocrinology Diabetes and Obesity
- PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development
- (2016) Coralie Drelon et al. Nature Communications
- Activating mutations in CTNNB1 in aldosterone producing adenomas
- (2016) Tobias Åkerström et al. Scientific Reports
- Functional Zonation of the Adult Mammalian Adrenal Cortex
- (2016) Gavin P. Vinson Frontiers in Neuroscience
- CACNA1H Mutations Are Associated With Different Forms of Primary Aldosteronism
- (2016) Georgios Daniil et al. EBioMedicine
- Genetics of Aldosterone-Producing Adenoma in Korean Patients
- (2016) A. Ram Hong et al. PLoS One
- Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotype
- (2015) Ute I. Scholl et al. CLINICAL ENDOCRINOLOGY
- Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas
- (2015) Tobias Åkerström et al. ENDOCRINE-RELATED CANCER
- Pathogenesis of Adrenal Aldosterone-Producing Adenomas Carrying Mutations of the Na+/K+-ATPase
- (2015) J. Stindl et al. ENDOCRINOLOGY
- Genetics of primary bilateral macronodular adrenal hyperplasia: a model for early diagnosis of Cushing's syndrome?
- (2015) Ludivine Drougat et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- PRKACA mutations in cortisol-producing adenomas and adrenal hyperplasia: a single-center study of 60 cases
- (2015) A. Thiel et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- TheARMC5gene shows extensive genetic variance in primary macronodular adrenocortical hyperplasia
- (2015) Ricardo Correa et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- ARMC5mutations in a large French-Canadian family with cortisol-secreting β-adrenergic/vasopressin responsive bilateral macronodular adrenal hyperplasia
- (2015) Isabelle Bourdeau et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Germline PRKACA amplification leads to Cushing syndrome caused by 3 adrenocortical pathologic phenotypes
- (2015) J. Aidan Carney et al. HUMAN PATHOLOGY
- Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing AdenomaNovelty and Significance
- (2015) Fabio Luiz Fernandes-Rosa et al. HYPERTENSION
- Clinical Characteristics of Somatic Mutations in Chinese Patients With Aldosterone-Producing AdenomaNovelty and Significance
- (2015) Fang-Fang Zheng et al. HYPERTENSION
- Comparison of Cardiovascular Complications in Patients with and without KCNJ5 Gene Mutations Harboring Aldosterone-producing Adenomas
- (2015) Takumi Kitamoto et al. Journal of Atherosclerosis and Thrombosis
- ARMC5Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences
- (2015) Stéphanie Espiard et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Meta-Analysis of Somatic KCNJ5 K+Channel Mutations In 1636 Patients With an Aldosterone-Producing Adenoma
- (2015) Livia Lenzini et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- NovelKCNJ5Mutations in Sporadic Aldosterone-Producing Adenoma Reduce Kir3.4 Membrane Abundance
- (2015) Chih-Jen Cheng et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Primary Aldosteronism andARMC5Variants
- (2015) Mihail Zilbermint et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Molecular and Clinical Evidence for anARMC5Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations Are Associated With Both Primary Macronodular Adrenal Hyperplasia and Meningioma
- (2015) Ulf Elbelt et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Prevalence and Characterization of Somatic Mutations in Chinese Aldosterone-Producing Adenoma Patients
- (2015) Baojun Wang et al. MEDICINE
- Paracrine control of steroidogenesis by serotonin in adrenocortical neoplasms
- (2015) H. Lefebvre et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Immunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas
- (2015) Silvia Monticone et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Novel Insertion Mutation in KCNJ5 Channel Produces Constitutive Aldosterone Release From H295R Cells
- (2015) Iris Hardege et al. MOLECULAR ENDOCRINOLOGY
- Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations
- (2015) Ada E.D. Teo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands
- (2015) Koshiro Nishimoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition
- (2015) Aude Salomon et al. Oncotarget
- Prevalence and clinical correlates of somatic mutation in aldosterone producing adenoma-Taiwanese population
- (2015) Vin-Cent Wu et al. Scientific Reports
- Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism
- (2015) Ute I Scholl et al. eLife
- Somatic mutations of the catalytic subunit of cyclic AMP-dependent protein kinase (PRKACA) gene in Japanese patients with several adrenal adenomas secreting cortisol [Rapid Communication]
- (2014) Yasuyo Nakajima et al. ENDOCRINE JOURNAL
- Pharmacology and Pathophysiology of Mutated KCNJ5 Found in Adrenal Aldosterone-Producing Adenomas
- (2014) P. Tauber et al. ENDOCRINOLOGY
- Discordant Genotype-Phenotype Correlation in Familial Hyperaldosteronism Type III with KCNJ5 Gene Mutation: A Patient Report and Review of the Literature
- (2014) Masanori Adachi et al. Hormone Research in Paediatrics
- Role for Germline Mutations and a Rare Coding Single Nucleotide Polymorphism Within the KCNJ5 Potassium Channel in a Large Cohort of Sporadic Cases of Primary Aldosteronism
- (2014) Meena Murthy et al. HYPERTENSION
- Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma
- (2014) Fabio Luiz Fernandes-Rosa et al. HYPERTENSION
- ARMC5Mutations Are Common in Familial Bilateral Macronodular Adrenal Hyperplasia
- (2014) Lucia Gagliardi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- ARMC5Mutations Are a Frequent Cause of Primary Macronodular Adrenal Hyperplasia
- (2014) Guilherme Asmar Alencar et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Channels and Pumps in Aldosterone-Producing Adenomas
- (2014) Celso E. Gomez-Sanchez JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Novel Somatic Mutations in the Catalytic Subunit of the Protein Kinase A as a Cause of Adrenal Cushing's Syndrome: A European Multicentric Study
- (2014) Guido Di Dalmazi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Macronodular Adrenal Hyperplasia due to Mutations in an Armadillo Repeat Containing 5 (ARMC5) Gene: A Clinical and Genetic Investigation
- (2014) Fabio R. Faucz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Novel KCNJ5-insT149 Somatic Mutation Close to, but Outside, the Selectivity Filter Causes Resistant Hypertension by Loss of Selectivity for Potassium
- (2014) Maniselvan Kuppusamy et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Adrenal Nodularity and Somatic Mutations in Primary Aldosteronism: One Node Is the Culprit?
- (2014) T. Dekkers et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors
- (2014) Gerald Goh et al. NATURE GENETICS
- Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome
- (2014) Felix Beuschlein et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome
- (2014) Y. Cao et al. SCIENCE
- Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome
- (2014) Y. Sato et al. SCIENCE
- Primary bilateral macronodular adrenal hyperplasia
- (2014) Agostino De Venanzi et al. Current Opinion in Endocrinology Diabetes and Obesity
- Complementary somatic mutations of KCNJ5, ATP1A1, and ATP2B3 in sporadic aldosterone producing adrenal adenomas
- (2013) Ravi Kumar Dutta et al. ENDOCRINE-RELATED CANCER
- MECHANISMS IN ENDOCRINOLOGY: Autocrine/paracrine regulatory mechanisms in adrenocortical neoplasms responsible for primary adrenal hypercorticism
- (2013) H Lefebvre et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Lack of influence of somatic mutations on steroid gradients during adrenal vein sampling in aldosterone-producing adenoma patients
- (2013) Andrea Oßwald et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production
- (2013) Annabel Berthon et al. HUMAN MOLECULAR GENETICS
- Cardiovascular Complications Associated With Primary Aldosteronism
- (2013) Sébastien Savard et al. HYPERTENSION
- Somatic ATP1A1 , ATP2B3 , and KCNJ5 Mutations in Aldosterone-Producing Adenomas
- (2013) Tracy Ann Williams et al. HYPERTENSION
- Long-Term Cardio- and Cerebrovascular Events in Patients With Primary Aldosteronism
- (2013) Paolo Mulatero et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Novel Y152C KCNJ5 Mutation Responsible for Familial Hyperaldosteronism Type III
- (2013) Silvia Monticone et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling
- (2013) Sheerazed Boulkroun et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension
- (2013) Elena A B Azizan et al. NATURE GENETICS
- Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism
- (2013) Ute I Scholl et al. NATURE GENETICS
- Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension
- (2013) Felix Beuschlein et al. NATURE GENETICS
- ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome
- (2013) Guillaume Assié et al. NEW ENGLAND JOURNAL OF MEDICINE
- Demonstration of Blood Pressure-Independent Noninfarct Myocardial Fibrosis in Primary Aldosteronism
- (2012) E. Marie Freel et al. Circulation-Cardiovascular Imaging
- KCNJ5 mutations in aldosterone- and cortisol-co-secreting adrenal adenomas [Rapid Communication]
- (2012) Masanobu Yamada et al. ENDOCRINE JOURNAL
- Potassium Channel Mutant KCNJ5 T158A Expression in HAC-15 Cells Increases Aldosterone Synthesis
- (2012) Kenji Oki et al. ENDOCRINOLOGY
- Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas
- (2012) Elena A.B. Azizan et al. HYPERTENSION
- Prevalence, Clinical, and Molecular Correlates of KCNJ5 Mutations in Primary Aldosteronism
- (2012) Sheerazed Boulkroun et al. HYPERTENSION
- Phosphodiesterase 11A (PDE11A) Gene Defects in Patients with ACTH-Independent Macronodular Adrenal Hyperplasia (AIMAH): Functional Variants May Contribute to Genetic Susceptibility of Bilateral Adrenal Tumors
- (2012) Delphine Vezzosi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Expression and Mutations of KCNJ5 mRNA in Japanese Patients with Aldosterone-Producing Adenomas
- (2012) Ryo Taguchi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Somatic Mutations in theKCNJ5Gene Raise the Lateralization Index: Implications for the Diagnosis of Primary Aldosteronism by Adrenal Vein Sampling
- (2012) Teresa M. Seccia et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Microarray, qPCR, andKCNJ5Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors
- (2012) Elena A. B. Azizan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Zona glomerulosa cells of the mouse adrenal cortex are intrinsic electrical oscillators
- (2012) Changlong Hu et al. JOURNAL OF CLINICAL INVESTIGATION
- Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma
- (2012) Meena Murthy et al. JOURNAL OF HYPERTENSION
- Adrenal Nodular Hyperplasia in Hereditary Leiomyomatosis and Renal Cell Cancer
- (2012) Brian Shuch et al. JOURNAL OF UROLOGY
- Role of KCNJ5 in familial and sporadic primary aldosteronism
- (2012) Paolo Mulatero et al. Nature Reviews Endocrinology
- Comprehensive Re-Sequencing of Adrenal Aldosterone Producing Lesions Reveal Three Somatic Mutations near the KCNJ5 Potassium Channel Selectivity Filter
- (2012) Tobias Åkerström et al. PLoS One
- Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5
- (2012) U. I. Scholl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aldosterone-Producing Adenoma Formation in the Adrenal Cortex Involves Expression of Stem/Progenitor Cell Markers
- (2011) Sheerazed Boulkroun et al. ENDOCRINOLOGY
- Adrenal involvement in MEN1. Analysis of 715 cases from the Groupe d'étude des Tumeurs Endocrines database
- (2011) B Gatta-Cherifi et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Prevalence of Primary Aldosteronism in Patient's Cohorts and in Population-based Studies - A Review of the Current Literature
- (2011) A. Hannemann et al. HORMONE AND METABOLIC RESEARCH
- Frequency of Familial Hyperaldosteronism Type 1 in a Hypertensive Pediatric Population
- (2011) Marlene Aglony et al. HYPERTENSION
- Prevalence and Characteristics of Familial Hyperaldosteronism
- (2011) Paolo Mulatero et al. HYPERTENSION
- KCNJ5 Mutations in European Families With Nonglucocorticoid Remediable Familial Hyperaldosteronism
- (2011) Paolo Mulatero et al. HYPERTENSION
- Cardiovascular Complications of Patients with Aldosteronism Associated with Autonomous Cortisol Secretion
- (2011) Yasuyo Nakajima et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Concurrent primary aldosteronism and subclinical cortisol hypersecretion
- (2011) Francesco Fallo et al. JOURNAL OF HYPERTENSION
- K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension
- (2011) M. Choi et al. SCIENCE
- Inactivation of the APC Gene Is Constant in Adrenocortical Tumors from Patients with Familial Adenomatous Polyposis but Not Frequent in Sporadic Adrenocortical Cancers
- (2010) S. Gaujoux et al. CLINICAL CANCER RESEARCH
- TASK1 and TASK3 Potassium Channels: Determinants of Aldosterone Secretion and Adrenocortical Zonation
- (2010) S. Bandulik et al. HORMONE AND METABOLIC RESEARCH
- Constitutive β-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development
- (2010) Annabel Berthon et al. HUMAN MOLECULAR GENETICS
- Adrenal Cortex Remodeling and Functional Zona Glomerulosa Hyperplasia in Primary Aldosteronism
- (2010) Sheerazed Boulkroun et al. HYPERTENSION
- Adrenocortical Zonation in Humans under Normal and Pathological Conditions
- (2010) Koshiro Nishimoto et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Cushing Syndrome in the McCune-Albright Syndrome
- (2010) Rebecca J. Brown et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Wnt/β-Catenin Pathway Activation in Adrenocortical Adenomas Is Frequently due to Somatic CTNNB1-Activating Mutations, Which Are Associated with Larger and Nonsecreting Tumors: A Study in Cortisol-Secreting and -Nonsecreting Tumors
- (2010) Stéphane Bonnet et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Signaling complexes of voltage-gated sodium and calcium channels
- (2010) William A. Catterall NEUROSCIENCE LETTERS
- Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC
- (2009) Madhuri Bhandaru et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- ACTH-independent macronodular adrenal hyperplasia
- (2009) André Lacroix BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Clinical and Genetic Heterogeneity, Overlap with Other Tumor Syndromes, and Atypical Glucocorticoid Hormone Secretion in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Compared with Other Adrenocortical Tumors
- (2009) Hui-Pin Hsiao et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Role of DNA methylation in the tissue-specific expression of the CYP17A1 gene for steroidogenesis in rodents
- (2009) Elika Missaghian et al. JOURNAL OF ENDOCRINOLOGY
- SERKAL Syndrome: An Autosomal-Recessive Disorder Caused by a Loss-of-Function Mutation in WNT4
- (2008) Hannah Mandel et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Phosphodiesterase 11A (PDE11A) and Genetic Predisposition to Adrenocortical Tumors
- (2008) R. Libe et al. CLINICAL CANCER RESEARCH
- Targeted disruption of -catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex
- (2008) A. C. Kim et al. DEVELOPMENT
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started