Multi-analyte biosensor interface for real-time monitoring of 3D microtissue spheroids in hanging-drop networks

3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis

(2015) Jin-Young Kim et al.   JOURNAL OF BIOTECHNOLOGY

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow

(2015) Mandy B. Esch et al.   LAB ON A CHIP

A lung-on-a-chip array with an integrated bio-inspired respiration mechanism

(2015) Andreas O. Stucki et al.   LAB ON A CHIP

Enzyme SU-8 microreactors: simple tools for cell-culture monitoring

(2015) Sara Talaei et al.   Microfluidics and Nanofluidics

Real-time metabolome profiling of the metabolic switch between starvation and growth

(2015) Hannes Link et al.   NATURE METHODS

Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes

(2015) Philippe Beauchamp et al.   TISSUE ENGINEERING PART C-METHODS

How multi-organ microdevices can help foster drug development

(2014) Mandy B. Esch et al.   ADVANCED DRUG DELIVERY REVIEWS

Fully Integrated CMOS Microsystem for Electrochemical Measurements on 32 × 32 Working Electrodes at 90 Frames Per Second

(2014) Joerg Rothe et al.   ANALYTICAL CHEMISTRY

Organs-on-a-chip: a new tool for drug discovery

(2014) Alessandro Polini et al.   Expert Opinion on Drug Discovery

Advances in 3D cell culture technologies enabling tissue-like structures to be createdin vitro

(2014) Eleanor Knight et al.   JOURNAL OF ANATOMY

An in vitro osteosarcoma 3D microtissue model for drug development

(2014) Markus Rimann et al.   JOURNAL OF BIOTECHNOLOGY

Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis

(2014) Olivier Frey et al.   Nature Communications

Advances in Microfluidic Materials, Functions, Integration, and Applications

(2013) Pamela N. Nge et al.   CHEMICAL REVIEWS

Cell culture monitoring for drug screening and cancer research: a transparent, microfluidic, multi-sensor microsystem

(2013) Andreas Weltin et al.   LAB ON A CHIP

Metabolic Multianalyte Microphysiometry Reveals Extracellular Acidosis is an Essential Mediator of Neuronal Preconditioning

(2012) Jennifer R. McKenzie et al.   ACS Chemical Neuroscience

Multi-cell type human liver microtissues for hepatotoxicity testing

(2012) S. Messner et al.   ARCHIVES OF TOXICOLOGY

Microtissue size and hypoxia in HTS with 3D cultures

(2012) Amish Asthana et al.   DRUG DISCOVERY TODAY

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

New Approaches for Carbon Nanotubes-Based Biosensors and Their Application to Cell Culture Monitoring

(2012) C. Boero et al.   IEEE Transactions on Biomedical Circuits and Systems

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Micro Total Analysis Systems for Cell Biology and Biochemical Assays

(2011) Michelle L. Kovarik et al.   ANALYTICAL CHEMISTRY

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Analyzing shear stress-induced alignment of actin filaments in endothelial cells with a microfluidic assay

(2010) A. D. van der Meer et al.   Biomicrofluidics

Enzyme-coated microelectrodes to monitor lactate production in a nanoliter microfluidic cell culture device

(2010) Igor A. Ges et al.   BIOSENSORS & BIOELECTRONICS

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Design and prototyping of a chip-based multi-micro-organoid culture system for substance testing, predictive to human (substance) exposure

(2010) Frank Sonntag et al.   JOURNAL OF BIOTECHNOLOGY

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

Continuous-flow multi-analyte biosensor cartridge with controllable linear response range

(2010) Olivier Frey et al.   LAB ON A CHIP

A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip

(2010) Jong Hwan Sung et al.   LAB ON A CHIP

A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices

(2010) Paul M. van Midwoud et al.   LAB ON A CHIP

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Enzyme electrodes to monitor glucose consumption of single cardiac myocytes in sub-nanoliter volumes

(2009) Igor A. Ges et al.   BIOSENSORS & BIOELECTRONICS

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments

(2009) Chi Zhang et al.   LAB ON A CHIP

Glucose and Lactate Biosensors for Scanning Electrochemical Microscopy Imaging of Single Live Cells

(2008) Madalina Ciobanu et al.   ANALYTICAL CHEMISTRY

Increased levels of superoxide and H2O2mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

(2008) Nùkhet Aykin-Burns et al.   BIOCHEMICAL JOURNAL

3D cell culture opens new dimensions in cell-based assays

(2008) Bradley A. Justice et al.   DRUG DISCOVERY TODAY

Electrochemical Biosensors - Sensor Principles and Architectures

(2008) Dorothee Grieshaber et al.   SENSORS

Integrated Electrochemical Analysis System with Microfluidic and Sensing Functions

(2008) Wataru Satoh et al.   SENSORS

Three-Dimensional Cell Culture Matrices: State of the Art

(2008) Jungwoo Lee et al.   TISSUE ENGINEERING PART B-REVIEWS