Article
Microbiology
Signe Marie Mehl Hojgaard, Omid Rezahosseini, Jenny Dahl Knudsen, Natascha Josephine Ulstrand Fuglebjerg, Marianne Skov, Susanne Dam Nielsen, Zitta Barrella Harboe
Summary: Delftia acidovorans (D. acidovorans) is a Gram-negative bacteria that mainly affects male patients with preexisting comorbidities, including malignancies. Most patients have polymicrobial cultures, predominantly with Pseudomonas spp. and Stenotrophomonas maltophilia. More than 85% of D. acidovorans isolates are susceptible to meropenem or ceftazidime, while 88% and 62% of isolates are resistant to gentamicin and colistin, respectively.
MICROBIOLOGY SPECTRUM
(2022)
Article
Biotechnology & Applied Microbiology
Jackson D. Harris, Collin M. Coon, Megan E. Doherty, Eamon A. McHugh, Margaret C. Warner, Conley L. Walters, Olivia M. Orahood, Abigail E. Loesch, David C. Hatfield, John C. Sitko, Erin A. Almand, J. Jordan Steel
Summary: Per- and Polyfluorinated alkyl substances (PFAS) are synthetic compounds widely used worldwide, but recent concerns have arisen over their health effects. This study identified Delftia acidovorans as a microorganism with the potential to degrade PFAS, offering a novel approach for the removal of PFAS contamination through microbial remediation.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY
(2022)
Article
Environmental Sciences
Ana C. Afonso, Ines B. Gomes, Maria Jose Saavedra, Lucia C. Similes, Manuel Similes
Summary: Coaggregation plays an important role in the development of multispecies biofilms. Delftia acidovorans has been found to have coaggregating ability through polysaccharide-protein and protein-protein interactions. Its presence benefits biofilm formation by Citrobacter freundii and Pseudomonas putida strains.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Ke Li, Xue Liu, Wenlu Zuo, Na Wu
Summary: The aim of this study was to reveal the antibiotic resistance genes and pathogenic genes in a novel conditional pathogenic strain-D. acidovorans B804. The experimental results showed that D. acidovorans B804 had multidrug resistance, and 403 genes associated with antibiotic resistances and 89 pathogenic genes were predicted. Some of these genes might be capable of causing diseases to human.
BIOCHEMICAL GENETICS
(2023)
Article
Microbiology
Sooyeon Song, Jun-Seob Kim, Ryota Yamasaki, Sejong Oh, Michael J. Benedik, Thomas K. Wood
Summary: Cryptic prophages are not genomic junk but play a crucial role in stress responses, affecting persister cell resuscitation. Deleting these prophages increases persister cell resuscitation by activating the phosphate import system to control cell exit from dormancy.
ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Tomotaka Ohkubo, Yasuhiko Matsumoto, Otomi Cho, Yuki Ogasawara, Takashi Sugita
Summary: The proportion of Staphylococcus aureus in the skin microbiome is associated with the severity of inflammation in atopic dermatitis, and the balance between Staphylococcus epidermidis and S. aureus is crucial for maintaining healthy skin. Heat-treated culture supernatant of Delftia acidovorans inhibits the growth of S. epidermidis by inducing the production of reactive oxygen species via the TCA cycle.
Article
Immunology
Jaime Gazola Filho, Natalia Leal Vizoto, Maria Luiza de Aguiar Loesch, Marina Dias de Sena, Danielle Mendes da Camara, Karina Sampaio Caiaffa, Renata de Oliveira Mattos-Graner, Cristiane Duque
Summary: The study evaluated the effects of NaF and CHX at sub-MIC levels on the growth and biofilm formation of S. mutans, showing that these agents can influence bacterial growth and biofilm formation in a strain-dependent manner.
MICROBIAL PATHOGENESIS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Tian Zhang, Lingyun Xia, Zhejun Wang, Robert E. W. Hancock, Markus Haapasalo
Summary: DJK-5 treatment quickly killed biofilm bacteria and maintained a high level of dead bacteria for 1 week, while 1018 and CHX had less effective results, and the proportion of dead bacteria doubled within the first 7 days after exposure to CHX and 1018. The recovery time of biofilms was slow but similar after exposure to different treatments, with the recovery time after exposure to DJK-5 being longer.
JOURNAL OF ENDODONTICS
(2021)
Article
Microbiology
Hiu Ham Lee, Preethi Sudhakara, Shreena Desai, Kildare Miranda, Luis R. Martinez
Summary: METH mouth, a consequence of chronic methamphetamine (METH) use, is characterized by severe tooth decay and painful oral tissue inflammation, primarily due to reduced saliva production and increased bacterial growth facilitated by METH. Additionally, compulsive behaviors of METH users further exacerbate this oral condition.
Article
Dentistry, Oral Surgery & Medicine
Naiera Zayed, Nico Boon, Kristel Bernaerts, Ioanna Chatzigiannidou, Wannes Van Holm, Tim Verspecht, Wim Teughels
Summary: The study found that different chlorhexidine mouthrinses have varying effects on oral biofilms, and these effects appear to be product-dependent and influenced by their compositions and formulations.
JOURNAL OF PERIODONTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Heitor Ceolin Araujo, Juliano Pelim Pessan, Anne Caroline Morais Caldeira, Caio Sampaio, Marcelo Jose dos Santos Oliveira, Douglas Henrique Sales, Silvio Rainho Teixeira, Carlos Jose Leopoldo Constantino, Alberto Carlos Botazzo Delbem, Sandra Helena Penha Oliveira, Gordon Ramage, Douglas Roberto Monteiro
Summary: This study developed and characterized a dual nanocarrier of chlorhexidine and fluconazole, and evaluated its antibiofilm and cytotoxic effects. The results showed that the dual nanocarrier had superior antibiofilm effects compared to the combination of chlorhexidine and fluconazole, without increasing cytotoxicity.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jun-Hyuk Choi, Eun-Ha Jung, Eun-Song Lee, Hoi-In Jung, Baek-Il Kim
Summary: This study evaluated the anti-biofilm activity of chlorhexidine-releasing elastomerics (CRE) and found that they exhibited effective anti-biofilm and demineralization-inhibiting effects. Among the CRE variants, CRE 1 using dichloromethane as the solvent showed the most promising results against biofilms.
JOURNAL OF DENTISTRY
(2022)
Article
Microbiology
Jackson Harris, Marie Gross, Jeremy Kemball, Sanaz Farajollahi, Patrick Dennis, John Sitko, J. Jordan Steel, Erin Almand, Nancy Kelley-Loughnane, Vanessa A. Varaljay
Summary: Delftia acidovorans strain D4B is an aerobic bacterium isolated from soil, with a genome size of 6.26 Mbp and a G+C content of 67%. The genome encodes enzymes potentially involved in the degradation of fluorinated compounds.
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2021)
Article
Environmental Sciences
Juan Pablo Portilla Llerena, Raul Lima Coasaca, Herbert Omar Lazo Rodriguez, Sofia Angela Portilla Llerena, Ysabel Diaz Valencia, Paulo Mazzafera
Summary: Cu pollution is a problem in mining areas in Peru. Four species growing in copper-contaminated areas in Arequipa, Peru were evaluated for their phytoextraction capacity, physiological and proteomic responses. The study found that Bacharis salicifolia and Chenopodium murale were the most sensitive species, but had greater Cu phytoextraction capacity and accumulation in the biomass.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Biochemical Research Methods
Razan N. Alnahhas, Mary J. Dunlop
Summary: Stress response mechanisms in bacteria play a crucial role in their survival when facing different challenges. These mechanisms can vary across cells and time, leading to heterogeneous phenotypes at the single-cell level. These phenotypes, along with other cell features, contribute to the overall population-level response to stress and can involve diverging and coordinating actions such as bet-hedging and biofilm production. Understanding the combined impact of these effects is important for the survival of bacterial communities.
CURRENT OPINION IN BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Ran An, Sahar Alshalchi, Peter Breimhurst, Jeannette Munoz-Aguayo, Christian Flores-Figueroa, Sinisa Vidovic
Article
Microbiology
Seyed Asghar Havaei, Mehrdad Halaji, Sinisa Vidovic, Jo-Anne R. Dillon, Mohsen Karbalaei, Fahimeh Ghanbari, Amirmorteza Ebrahimzadeh Namvar, Bahram Nasr Esfahani, Seyed Mehdi Havaei, Amir Azimian
JUNDISHAPUR JOURNAL OF MICROBIOLOGY
(2017)
Article
Microbiology
Sahar Alshalchi, Shivdeep S. Hayer, Ran An, Jeannette Munoz-Aguayo, Christian Flores-Figueroa, Ryan Nguyen, Dale Lauer, Karen Olsen, Julio Alvarez, David Boxrud, Carol Cardona, Sinisa Vidovic
FRONTIERS IN MICROBIOLOGY
(2017)
Article
Biochemical Research Methods
Sinisa Vidovic, Prabhakara Medihala, James J. Dynes, Prasad Daida, Vladimir Vujanovic, Adam P. Hitchcock, Deeksha Shetty, Haixia Zhang, David R. Brown, John R. Lawrence, Darren R. Korber
Article
Microbiology
Sinisa Vidovic, Ran An, Aaron Rendahl
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Environmental Sciences
John R. Lawrence, Marley J. Waiser, George D. W. Swerhone, Julie L. Roy, Armelle Paule, Darren R. Korber
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Deeksha Shetty, Juan E. Abrahante, Samuel M. Chekabab, Xuxiaochen Wu, Darren R. Korber, Sinisa Vidovic
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Article
Biochemistry & Molecular Biology
Xiaoying Liu, Misara Omar, Juan E. Abrahante, Kakambi V. Nagaraja, Sinisa Vidovic
Article
Biochemistry & Molecular Biology
Xiaoying Liu, Misara Omar, Kakambi Nagaraja, Sagar M. Goyal, Sinisa Vidovic
Summary: The lack of the CpxR regulator induces multifaceted stress responses affecting key biomolecules in both the envelope and cytosol. Additionally, the increased cpxR mutant showed specific responses to CHX treatment. These findings provide potential cellular targets for the development of effective antimicrobial agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Saili Chalke, Sinisa Vidovic, Graham C. Fletcher, Jon Palmer, Steve Flint
Summary: In this study, the influence of magnesium, calcium, and sodium on biofilm formation in four isolates of L. monocytogenes from seafood processing environments was investigated. The study showed that magnesium and calcium increased biofilm formation, while sodium had a lesser effect. These cations appeared to have a greater influence on the later stages of biofilm development.
Review
Food Science & Technology
Sinisa Vidovic, Gunaranjan Paturi, Sravani Gupta, Graham C. Fletcher
Summary: Listeria monocytogenes is a major foodborne pathogen with unique ecological and physiological characteristics. Its ability to multiply at refrigeration temperature and persist in the food processing environment has significant implications for food safety. Due to consumer demand for ready-to-eat and minimally processed food, effective approaches to control L. monocytogenes contamination are necessary. This review discusses the distinct lifestyle of L. monocytogenes and emerging food decontamination technologies for better control.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Infectious Diseases
Nikola Vidovic, Sinisa Vidovic
Article
Biology
Sinisa Vidovic, Xiaoying Liu, Ran An, Kristelle M. Mendoza, Juan E. Abrahante, Anup K. Johny, Kent M. Reed
Article
Microbiology
Deeksha Shetty, Alexander A. Grigoryan, Sahar Alshalchi, Niradha Withana Gamage, Julie Roy, John R. Lawrence, Sinisa Vidovic, Darren R. Korber
GENOME ANNOUNCEMENTS
(2017)