4.5 Article

Comorbidity of chronic diseases in the elderly: Patterns identified by a copula design for mixed responses

期刊

COMPUTATIONAL STATISTICS & DATA ANALYSIS
卷 88, 期 -, 页码 28-39

出版社

ELSEVIER
DOI: 10.1016/j.csda.2015.02.001

关键词

R-vine; Pair copula construction; GLM; LSOA II

向作者/读者索取更多资源

Joint modeling of multiple health related random variables is essential to develop an understanding for the public health consequences of an aging population. This is particularly true for patients suffering from multiple chronic diseases. The contribution is to introduce a novel model for multivariate data where some response variables are discrete and some are continuous. It is based on pair copula constructions (PCCs) and has two major advantages over existing methodology. First, expressing the joint dependence structure in terms of bivariate copulas leads to a computationally advantageous expression for the likelihood function. This makes maximum likelihood estimation feasible for large multidimensional data sets. Second, different and possibly asymmetric bivariate (conditional) marginal distributions are allowed which is necessary to accurately describe the limiting behavior of conditional distributions for mixed discrete and continuous responses. The advantages and the favorable predictive performance of the model are demonstrated using data from the Second Longitudinal Study of Aging (LSOA II). (C) 2015 Elsevier B.V. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Health Care Sciences & Services

New Composite Measure for ADL Limitations: Application to Predicting Nursing Home Placement for Michigan MI Choice Clients

Hyokyoung G. Hong, Hong-Su An, Erin Sarzynski, Kathleen Oberst

Summary: The study compared two composite ADL measures created by exploratory factor analysis and additive modeling and found that the self-care-based ADL limitations composite measure performed equally well in predicting nursing home admission as an additive measure considering all ADL limitations. This approach demonstrated improved interpretability while requiring just five measures.

MEDICAL CARE RESEARCH AND REVIEW (2021)

Article Physics, Multidisciplinary

Consistent Estimation of Generalized Linear Models with High Dimensional Predictors via Stepwise Regression

Alex Pijyan, Qi Zheng, Hyokyoung G. Hong, Yi Li

ENTROPY (2020)

Article Statistics & Probability

Inference for High-Dimensional Censored Quantile Regression

Zhe Fei, Qi Zheng, Hyokyoung G. Hong, Yi Li

Summary: This study proposes a novel method within the framework of global censored quantile regression to draw inference on the effects of high-dimensional predictors. The method investigates covariate-response associations over an interval of quantile levels and properly quantifies the uncertainty of the estimates.

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION (2023)

Article Multidisciplinary Sciences

Paramedic interactions with the packaging of medications and medical supplies: Poor package design has the potential to impact patient outcomes

Jiyon Lee, Rebecca E. Cash, Remle P. Crowe, Hyokyoung G. Hong, Ashish R. Panchal, Kami Silk, Marvin Helmker, Laura Bix

Summary: This study investigated packaging difficulties, coping strategies, and potential impacts on patient care in prehospital settings. Results showed that nearly 20% of respondents experienced difficulties identifying or opening medications and medical supplies in the past year, with a small percentage reporting negative impacts on patient care.

PLOS ONE (2021)

Letter Medicine, General & Internal

Comorbid conditions related to readmissions of Chinese older patients

Chunyang Li, Hyokyoung G. Hong, Zhiye Ying, Xiaoxi Zeng, Yi Li

CHINESE MEDICAL JOURNAL (2022)

Article Statistics & Probability

A Bayesian non-linear state space copula model for air pollution in Beijing

Alexander Kreuzer, Luciana Dalla Valle, Claudia Czado

Summary: Air pollution is a serious issue that can cause harm to human health. This paper proposes a new method to estimate the concentration of fine particulate matter and meteorological data in Beijing in 2014, which is flexible and accurately captures unusual high levels of air pollution.

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS (2022)

Article Medicine, General & Internal

Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults

Eleanor L. Watts, Charles E. Matthews, Joshua R. Freeman, Jessica S. Gorzelitz, Hyokyoung G. Hong, Linda M. Liao, Kathleen M. McClain, Pedro F. Saint-Maurice, Eric J. Shiroma, Steven C. Moore

Summary: Higher amounts of physical activity are associated with increased longevity. Different types of leisure time physical activities have different associations with mortality risk. Participating in 7.5 to less than 15 MET hours per week of any activity is significantly associated with reduced mortality risk.

JAMA NETWORK OPEN (2022)

Article Nursing

Utilization of Medicare's chronic care management services by primary care providers

Ann Annis, Hyokyoung G. Hong

Summary: This study conducted an observational study using Medicare Public Use Files from 2015 to 2018. It found that although chronic care management services increased each year, they remained underutilized. Increases in beneficiaries, percentage of dually enrolled, and primary care services predicted higher utilization of chronic care management.

NURSING OUTLOOK (2023)

Article Nutrition & Dietetics

Dietary Quality and Circulating Lipidomic Profiles in 2 Cohorts of Middle-Aged and Older Male Finnish Smokers and American Populations

Ting Zhang, Sabine Naudin, Hyokyoung G. Hong, Demetrius Albanes, Satu Mannisto, Stephanie J. Weinstein, Steven C. Moore, Rachael Z. Stolzenberg-Solomon

Summary: This study examined the associations between dietary quality indices and serum lipidomic profiles. The results showed that adherence to the Healthy Eating Index (HEI)-2015, Alternate HEI-2010 (AHEI-2010), and alternate Mediterranean Diet Index (aMED) were associated with serum lipid species, particularly triacylglycerols and docosahexaenoic acid (DHA)-containing species, which were related to components of seafood and plant proteins, eicosapentaenoic acid-DHA, fish, or fat ratio.

JOURNAL OF NUTRITION (2023)

Article Nutrition & Dietetics

Metabolomic Profiling of an Ultraprocessed Dietary Pattern in a Domiciled Randomized Controlled Crossover Feeding Trial

Lauren E. O'Connor, Kevin D. Hall, Kirsten A. Herrick, Jill Reedy, Stephanie T. Chung, Michael Stagliano, Amber B. Courville, Rashmi Sinha, Neal D. Freedman, Hyokyoung G. Hong, Paul S. Albert, Erikka Loftfield

Summary: This study aimed to identify metabolites that differ between dietary patterns high in or void of ultraprocessed foods (UPF) and provide insights into how UPF influences health. The results showed that there were 257 plasma metabolites and 606 24-hour urine metabolites that differed between the UPF dietary pattern and the unprocessed dietary pattern. These differential metabolites could serve as candidate biomarkers for UPF intake or metabolic response.

JOURNAL OF NUTRITION (2023)

Article Nutrition & Dietetics

Metabolomic Analysis of Vitamin E Supplement Use in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

Jungeun Lim, Hyokyoung G. G. Hong, Stephanie J. Weinstein, Mary C. Playdon, Amanda J. Cross, Rachael Stolzenberg-Solomon, Neal D. Freedman, Jiaqi Huang, Demetrius Albanes

Summary: The effects of vitamin E supplementation on cancer and other chronic diseases are unclear. This study compared the serum metabolomic profile of different vitamin E dosages and found significant associations between vitamin E supplementation and various metabolites, including C-22 lactone sulfate and androgens. The study also discovered distinct responses in steroid hormone pathways based on vitamin E dosages. Further research is needed to better understand the biological effects of vitamin E in relation to cancer and other chronic diseases.

NUTRIENTS (2023)

Article Mathematics, Interdisciplinary Applications

Quantile forward regression for high-dimensional survival data

Eun Ryung Lee, Seyoung Park, Sang Kyu Lee, Hyokyoung G. Hong

Summary: Existing prediction models are not tailored to individual interests and mainly target average people. We propose a quantile forward regression model for high-dimensional survival data to accommodate the heterogeneous characteristics of covariates and provide a flexible risk model.

LIFETIME DATA ANALYSIS (2023)

Article Mathematical & Computational Biology

Varying-coefficients for regional quantile via KNN-based LASSO with applications to health outcome study

Seyoung Park, Eun Ryung Lee, Hyokyoung G. G. Hong

Summary: In this paper, a novel framework for dynamic modeling of the associations between health outcomes and risk factors is proposed, which captures the time-varying effects of age. The proposed method combines varying-coefficients regional quantile regression via K-nearest neighbors fused Lasso to better model the effects of risk factors on health outcomes.

STATISTICS IN MEDICINE (2023)

Article Health Policy & Services

Rethinking the Digital Divide: Using an Internet Survey in a Flint Water Crisis Medicaid Population

Sabrina Ford, Kathleen Oberst, Joan Ilardo, Hong Su An, Nicole Jones, Hyokyoung G. Hong, Karen Clark, Zhehui Luo

Summary: This project examined the preferred mode of response to a health services survey, finding that the majority of participants preferred to respond via the internet, with a significant proportion using smartphones. The study also identified differences in internet usage based on race and income, highlighting the persistence of the digital divide. These findings can inform future health programming and telehealth initiatives, particularly in light of the COVID-19 pandemic.

JOURNAL OF HEALTH CARE FOR THE POOR AND UNDERSERVED (2022)

Article Economics

Vine copula mixture models and clustering for non-Gaussian data

Ozge Sahin, Claudia Czado

Summary: A novel vine copula mixture model is proposed to capture asymmetric tail dependencies and non-elliptical clusters in continuous data. The model selection and parameter estimation problems are discussed, and a new model-based clustering algorithm is formulated.

ECONOMETRICS AND STATISTICS (2022)

Article Computer Science, Interdisciplinary Applications

One point per cluster spatially balanced sampling

Blair Robertson, Chris Price

Summary: Spatial sampling designs are crucial for accurate estimation of population parameters. This study proposes a new design method that generates samples with good spatial spread and performs favorably compared to existing designs.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Simultaneous confidence region of an embedded one-dimensional curve in multi-dimensional space

Hiroya Yamazoe, Kanta Naito

Summary: This paper focuses on the simultaneous confidence region of a one-dimensional curve embedded in multi-dimensional space. An estimator of the curve is obtained through local linear regression on each variable in multi-dimensional data. A method to construct a simultaneous confidence region based on this estimator is proposed, and theoretical results for the estimator and the region are developed. The effectiveness of the region is demonstrated through simulation studies and applications to artificial and real datasets.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Efficient and robust optimal design for quantile regression based on linear programming

Cheng Peng, Drew P. Kouri, Stan Uryasev

Summary: This paper introduces a novel optimal experimental design method for quantifying the distribution tails of uncertain system responses. The method minimizes the variance or conditional value-at-risk of the upper bound of the predicted quantile, and estimates the data uncertainty using quantile regression. The optimal design problems are solved as linear programming problems, making the proposed methods efficient even for large datasets.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Multi-block alternating direction method of multipliers for ultrahigh dimensional quantile fused regression

Xiaofei Wu, Hao Ming, Zhimin Zhang, Zhenyu Cui

Summary: This paper proposes a model that combines quantile regression and fused LASSO penalty, and introduces an iterative algorithm based on ADMM to solve high-dimensional datasets. The paper proves the global convergence and comparable convergence rates of the algorithm, and analyzes the theoretical properties of the model. Numerical experimental results support the superior performance of the model.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Nonparametric augmented probability weighting with sparsity

Xin He, Xiaojun Mao, Zhonglei Wang

Summary: This paper proposes a nonparametric imputation method with sparsity to estimate the finite population mean, using an efficient kernel method and sparse learning for estimation. An augmented inverse probability weighting framework is adopted to achieve a central limit theorem for the proposed estimator under regularity conditions.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Conditional-mean multiplicative operator models for count time series

Christian H. Weiss, Fukang Zhu

Summary: This study introduces a multiplicative error model (CMEMs) for discrete-valued count time series, which is closely related to the integer-valued generalized autoregressive conditional heteroscedasticity (INGARCH) models. It derives the stochastic properties and estimation approaches of different types of INGARCH-CMEMs, and demonstrates their performance and application through simulations and real-world data examples.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Hybrid exact-approximate design approach for sparse functional data

Ming-Hung Kao, Ping-Han Huang

Summary: Optimal designs for sparse functional data under the functional empirical component (FEC) settings are investigated. New computational methods and theoretical results are developed to efficiently obtain optimal exact and approximate designs. A hybrid exact-approximate design approach is proposed and demonstrated to be efficient through simulation studies and a real example.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

GP-BART: A novel Bayesian additive regression trees approach using Gaussian processes

Mateus Maia, Keefe Murphy, Andrew C. Parnell

Summary: The Bayesian additive regression trees (BART) model is a powerful ensemble method for regression tasks, but its lack of smoothness and explicit covariance structure can limit its performance. The Gaussian processes Bayesian additive regression trees (GP-BART) model addresses this limitation by incorporating Gaussian process priors, resulting in superior performance in various scenarios.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Additive partially linear model for pooled biomonitoring data

Xichen Mou, Dewei Wang

Summary: Human biomonitoring is a method of monitoring human health by measuring the accumulation of harmful chemicals in the body. To reduce the high cost of chemical analysis, researchers have adopted a cost-effective approach that combines specimens and analyzes the concentration of toxic substances in the pooled samples. To effectively interpret these aggregated measurements, a new regression framework is proposed by extending the additive partially linear model (APLM). The APLM is versatile in capturing the complex association between outcomes and covariates, making it valuable in assessing the complex interplay between chemical bioaccumulation and potential risk factors.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Laplace approximated quasi-likelihood method for heteroscedastic survival data

Lili Yu, Yichuan Zhao

Summary: The classical accelerated failure time model is a linear model commonly used for right censored survival data, but it cannot handle heteroscedastic survival data. This paper proposes a Laplace approximated quasi-likelihood method with a continuous estimating equation to address this issue, and provides estimation bias and confidence interval estimation formulas.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Standard error estimates in hierarchical generalized linear models

Shaobo Jin, Youngjo Lee

Summary: Hierarchical generalized linear models are widely used for fitting random effects models, but the standard error estimators receive less attention. Current standard error estimation methods are not necessarily accurate, and a sandwich estimator is proposed to improve the accuracy of standard error estimation.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Probability of default estimation in credit risk using mixture cure models

Rebeca Pelaez, Ingrid Van Keilegom, Ricardo Cao, Juan M. Vilar

Summary: This article proposes an estimator for the probability of default (PD) in credit risk, derived from a nonparametric conditional survival function estimator based on cure models. The asymptotic expressions for bias, variance, and normality of the estimator are presented. Through simulation and empirical studies, the performance and practical behavior of the nonparametric estimator are compared with other methods.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Joint modelling of the body and tail of bivariate data

L. M. Andre, J. L. Wadsworth, A. O'Hagan

Summary: This paper proposes a dependence model that captures the entire data range in multi-variable cases. By blending two copulas with different characteristics and using a dynamic weighting function for smooth transition, the model is able to flexibly capture various dependence structures.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Significance test for semiparametric conditional average treatment effects and other structural functions

Niwen Zhou, Xu Guo, Lixing Zhu

Summary: The paper investigates hypothesis testing regarding the potential additional contributions of other covariates to the structural function, given the known covariates. The proposed distance-based test, based on Neyman's orthogonality condition, effectively detects local alternatives and is robust to the influence of nuisance functions. Numerical studies and real data analysis demonstrate the importance of this test in exploring covariates associated with AIDS treatment effects.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)

Article Computer Science, Interdisciplinary Applications

Full uncertainty analysis for Bayesian nonparametric mixture models

Blake Moya, Stephen G. Walker

Summary: A full posterior analysis method for nonparametric mixture models using Gibbs-type prior distributions, including the well known Dirichlet process mixture (DPM) model, is presented. The method removes the random mixing distribution and enables a simple-to-implement Markov chain Monte Carlo (MCMC) algorithm. The removal procedure reduces some of the posterior uncertainty and introduces a novel replacement approach. The method only requires the probabilities of a new or an old value associated with the corresponding Gibbs-type exchangeable sequence, without the need for explicit representations of the prior or posterior distributions. This allows the implementation of mixture models with full posterior uncertainty, including one introduced by Gnedin. The paper also provides numerous illustrations and introduces an R-package called CopRe that implements the methodology.

COMPUTATIONAL STATISTICS & DATA ANALYSIS (2024)