Article
Materials Science, Multidisciplinary
Yuxiao Zhou, Warren Grayson
Summary: This article summarizes the application of 3D printing technology in craniofacial bone reconstruction. Through layer-by-layer manufacturing techniques, patient-specific craniofacial structures can be produced for esthetic purposes and functional restoration. The article also discusses the remaining hurdles and opportunities for growth in this technology.
Review
Engineering, Biomedical
Shi Hua Tan, Dun An Cliff Chua, Je Re Jeremiah Tang, Carine Bonnard, David Leavesley, Kun Liang
Summary: In vitro 3D human skin models are critical tools in advancing our understanding of skin physiology and function. Many of the existing reconstructed models are limited in terms of structure and complexity, thus failing to recapitulate native human skin. Hydrogels have been identified as useful scaffold materials for fabricating the dermal equivalent of 3D skin models, allowing for greater flexibility and control in scaffold properties and cellular incorporation. This review aims to provide a critical discussion of the biomaterial selection and design strategies in the construction of hydrogel-based full-thickness skin equivalents. At the same time, insights into future developments and technological advances which can accelerate progress in this field are offered.
ACTA BIOMATERIALIA
(2022)
Review
Polymer Science
Naiyu Cui, Chun-Yu Dai, Xuran Mao, Xun Lv, Yue Gu, Eui-Seok Lee, Heng-Bo Jiang, Yunhan Sun
Summary: Poloxamer, as a triblock copolymer with amphiphilicity and reversible thermal responsiveness, has wide application prospects in biomedicine. It plays a crucial role as injectable scaffolds in tissue engineering and 3D printing, creating an appropriate microenvironment for cell growth and vascular network formation.
Review
Polymer Science
Murugiah Krishani, Wong Yen Shin, Hazwani Suhaimi, Nonni Soraya Sambudi
Summary: Tissue engineering and scaffold fabrication techniques using bio-based natural materials for tissue regeneration applications are discussed in this review article. Bio-based natural materials are biocompatible and safe, making them highly recommended for scaffold development. Combining different materials and choosing appropriate fabrication techniques are important for designing reliable scaffolds.
Article
Polymer Science
Lei Li, Pengfei Lu, Yuting Liu, Junhe Yang, Shengjuan Li
Summary: In this study, 3D bioactive glass/lignocellulose composite scaffolds were successfully fabricated by 3D-printing with NMMO as the ink solvent. The scaffolds showed uniform macropores and rough surfaces, with excellent mechanical properties and hydroxyapatite-forming capability. They also exhibited low cytotoxicity to human bone marrow mesenchymal stem cells. These 3D-printed BG/cellulose scaffolds have potential applications in bone tissue engineering.
Review
Polymer Science
Sandya Shiranthi Athukorala, Tuan Sang Tran, Rajkamal Balu, Vi Khanh Truong, James Chapman, Naba Kumar Dutta, Namita Roy Choudhury
Summary: Electrically conductive hydrogels (ECHs) are a promising class of biomaterials for a wide range of biomedical applications, with 3D printing being an advanced technique for rapid fabrication of future biomedical implants and devices with versatile designs and adjustable functionalities. This review provides an overview of state-of-the-art 3D printed ECHs, discussing mechanisms of electrical conductivity, design considerations, and recent advances in formulation of 3D printable bioinks. Challenges and limitations of 3D printing of ECHs are identified, along with highlighting new 3D printing-based hybrid methods for selective deposition and controlled nanostructure fabrication.
Article
Pharmacology & Pharmacy
Silvia Pisani, Valeria Mauri, Erika Negrello, Valeria Friuli, Ida Genta, Rossella Dorati, Giovanna Bruni, Stefania Marconi, Ferdinando Auricchio, Andrea Pietrabissa, Marco Benazzo, Bice Conti
Summary: In this study, hybrid scaffolds were developed as a versatile platform for soft tissue regeneration. These scaffolds exhibited favorable cell adhesion and proliferation, and allowed for controlled drug release.
Article
Materials Science, Multidisciplinary
Dahong Kim, Jihye Lee, Ji Min Seok, Joo-Yun Jung, Jun Hee Lee, Jun Sik Lee, Kangwon Lee, Su A. Park
Summary: Abalone shell particles (ASPs) embedded in PCL scaffolds through 3D printing show potential for bone regeneration, with ASP25 group demonstrating the best cell viability and proliferation, making it the most suitable choice for bone scaffold fabrication.
MATERIALS & DESIGN
(2021)
Article
Materials Science, Multidisciplinary
Alperen Abaci, Gulden Camci-Unal, Murat Guvendiren
Summary: Three-dimensional (3D) bioprinting is an emerging technology that can fabricate functional tissues and organs, replicating native tissue function. With its precise positioning of cellular materials and utilization of medical images, 3D bioprinting has enormous potential in biomedical applications, such as tissue engineering and regenerative medicine. It is a rapidly progressing field that has shown clinically relevant uses.
Review
Medicine, General & Internal
Seyed Ebrahim Alavi, Max Gholami, Hasan Ebrahimi Shahmabadi, Peter Reher
Summary: This literature review comprehensively discusses various aspects of resorbable scaffolds in bone tissue engineering, including scaffold design, materials, fabrication techniques, and advanced manufacturing methods. The review also explores surface modifications to improve cellular responses and describes the mechanisms of bone regeneration. Furthermore, the review delves into emerging areas of metamaterials and artificial intelligence applications in tissue engineering and regenerative medicine.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Engineering, Manufacturing
Tiandi Wang, Jianchao Zheng, Tianzhou Hu, Hongbo Zhang, Kun Fu, Ruixue Yin, Wenjun Zhang
Summary: 3D printing technology is used to fabricate bone tissue engineering scaffolds with calcium carbonate nanoparticles as a replacement for coral, improving biocompatibility and degradation. In vivo experiments show the scaffolds have the potential to promote bone growth and repair.
3D PRINTING AND ADDITIVE MANUFACTURING
(2021)
Article
Pharmacology & Pharmacy
Noah Z. Laird, Timothy M. Acri, Jaidev L. Chakka, Juliana C. Quarterman, Walla Malkawi, Satheesh Elangovan, Aliasger K. Salem
Summary: Tissue engineering is a interdisciplinary field that aims to create therapies that regenerate functional tissue by combining life sciences and engineering. The use of biologically active materials in scaffolds can enhance regeneration by enabling cell-scaffold interactions or releasing factors that aid in regeneration. Advanced techniques like nanotechnology in combination with 3D printing show promise in enhancing tissue engineering scaffolds for stimulating regeneration and cell interaction.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2021)
Article
Engineering, Biomedical
Santosh Kumar Parupelli, Sheikh Saudi, Narayan Bhattarai, Salil Desai
Summary: In this study, a composite scaffold of poly(epsilon-caprolactone) (PCL) and calcium magnesium phosphate (CMP) bioceramics was fabricated using 3D printing technology. The scaffolds mimic the rough textured architecture, porosity, and chemical composition of natural bone tissue matrices, and provide a favorable microenvironment for bone cell growth by releasing soluble calcium and magnesium ions. These 3D-printed scaffolds are a promising approach for bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Review
Engineering, Multidisciplinary
Andrew Johnston, Anthony Callanan
Summary: The limited regenerative capacity of the human body has created a need for alternative grafting materials. Tissue-engineered grafts, which integrate with host tissue, offer a potential solution. Achieving mechanical compatibility with the graft site is a challenge, and altering the mechanical properties through hybrid materials, multi-layer scaffold designs, and surface modifications have been explored.
Review
Materials Science, Multidisciplinary
Yujie Chen, Xutao Dong, Muhammad Shafiq, Gregory Myles, Norbert Radacsi, Xiumei Mo
Summary: Electrospinning is a technique used to fabricate nanofibrous three-dimensional scaffolds for tissue engineering, mimicking the extracellular matrix. The selection of materials, methods, and post-processing techniques significantly affect the structure, function, and applications of the scaffolds.
ADVANCED FIBER MATERIALS
(2022)
Article
Polymer Science
Krishnamurthy Prasad, Mostafa Nikzad, Cara M. Doherty, Igor Sbarski
JOURNAL OF APPLIED POLYMER SCIENCE
(2019)
Article
Engineering, Chemical
Abul B. M. Saifullah, Venkata V. K. Inampudi, Mostafa Nikzad, Igor Sbarski, Manwar Hussain
POLYMER ENGINEERING AND SCIENCE
(2020)
Article
Polymer Science
Krishnamurthy Prasad, Mostafa Nikzad, Igor Sbarski
JOURNAL OF APPLIED POLYMER SCIENCE
(2020)
Review
Polymer Science
K. Prasad, M. Nikzad, I. Sbarski
Summary: Permeation is a combination of diffusion and sorption phenomena, affected by factors such as polymer composition and different phases in the micro-structure. Computational techniques and semi-empirical modeling are used to simulate permeation. Semi-empirical models offer an effective pathway for predicting properties of composite polymers.
Review
Chemistry, Multidisciplinary
Azadeh Mirabedini, Andrew Ang, Mostafa Nikzad, Bronwyn Fox, Kin-Tak Lau, Nishar Hameed
Article
Chemistry, Multidisciplinary
Lachlan Thompson, Mostafa Nikzad, Igor Sbarski, Jalal Azadmanjiri, Jiawen Ren, Aimin Yu
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
(2020)
Review
Chemistry, Physical
Panneer Ponnusamy, Rizwan Abdul Rahman Rashid, Syed Hasan Masood, Dong Ruan, Suresh Palanisamy
Article
Physics, Applied
P. Prathumrat, I. Sbarski, E. Hajizadeh, M. Nikzad
Summary: Molecular dynamic simulation techniques were used to evaluate three force fields for modeling liquid crystalline elastomers, with SciPCFF showing the best agreement with experimental thermal and viscoelastic properties. The selected force field successfully predicted the shape memory process of LCEs, confirming its suitability for designing and predicting properties of typical LCE polymers.
JOURNAL OF APPLIED PHYSICS
(2021)
Review
Polymer Science
Peerawat Prathumrat, Mostafa Nikzad, Elnaz Hajizadeh, Reza Arablouei, Igor Sbarski
Summary: Shape memory elastomers (SMEs) are intelligent materials that can deform and recover shapes under applied force and external stimuli. With the increasing demand for smart materials and structures, SMEs present significant opportunities in various fields such as robotics, remotely actuated systems, and packaging. This review emphasizes the importance of systematic multi-scale modeling and artificial intelligence-assisted design in harnessing the potential of SMEs. It covers the synthesis, materials chemistry, and applications of SMEs, as well as the use of advanced manufacturing methods and current trends in industrial and biomedical applications.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2022)
Article
Polymer Science
Fareed Tamaddoni Jahromi, Mostafa Nikzad, Krishnamurthy Prasad, Johan Noren, Mats Isaksson, Alaleh Arian, Igor Sbarski
Summary: This study developed a composite material based on polypropylene (PP) for 3D printing and repairing of plastic components in the automotive industry. By adjusting the composition, the crystallinity of the material was reduced, thermal stability was improved, and mechanical properties were enhanced to enable repair of complex geometries. The developed composite filament was successfully used in a robotic cell to repair broken plastic lugs of a car headlight assembly.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Chemistry, Analytical
Metin Pekgor, Reza Arablouei, Mostafa Nikzad, Syed Masood
Summary: RFID tags are used to detect movement in structures, humans, or robots. This paper proposes a method of using passive RFID tags for structural health monitoring and validates its effectiveness through experiments.
Article
Polymer Science
Thanh Kim Mai Dang, Mostafa Nikzad, Vi Khanh Truong, Syed Masood, Chung Kim Nguyen, Igor Sbarski
Summary: This study investigates the use of EGaIn alloy and GnPs as reinforcements in cVE resin, and finds that EGaIn promotes the curing reaction of cVE, while GnPs enhance the strength and toughness of the cVE matrix. Both reinforcements show performance improvements, with EGaIn being more effective in enhancing flexural and impact strength, and GnPs being more effective in improving fracture toughness and fracture energy.
Article
Materials Science, Multidisciplinary
Riyan Rashid, Syed Masood, Dong Ruan, Suresh Palanisamy, Xiaodong Huang, Rizwan Abdul Rahman Rashid
Summary: The laser powder bed fusion (LPBF) method, also known as selective laser melting (SLM), is widely used in metal additive manufacturing (AM). In this study, the design optimization and validation of LPBF-printed AlSi12 metal parts were investigated. Different topologically optimized lattice beams were compared, and it was found that the 1 x 1 lattice beam performed the best in bending tests. The mechanical behavior of these beams was influenced by the design elements and a new material model or simulation technique is needed to overcome this issue.
Review
Chemistry, Multidisciplinary
Pritam K. Chakraborty, Jalal Azadmanjiri, Chokkakula L. P. Pavithra, Xiaojian Wang, Syed H. Masood, Suhash Ranjan Dey, James Wang
Article
Nanoscience & Nanotechnology
Lachlan Thompson, Jalal Azadmanjiri, Mostafa Nikzad, Igor Sbarski, James Wang, Aimin Yu
REVIEWS ON ADVANCED MATERIALS SCIENCE
(2019)
